CO2019010503A2 - Plataforma de identificación de péptidos inmunogénicos personalizada - Google Patents
Plataforma de identificación de péptidos inmunogénicos personalizadaInfo
- Publication number
- CO2019010503A2 CO2019010503A2 CONC2019/0010503A CO2019010503A CO2019010503A2 CO 2019010503 A2 CO2019010503 A2 CO 2019010503A2 CO 2019010503 A CO2019010503 A CO 2019010503A CO 2019010503 A2 CO2019010503 A2 CO 2019010503A2
- Authority
- CO
- Colombia
- Prior art keywords
- custom
- methods
- immunogenic peptide
- identification platform
- peptide identification
- Prior art date
Links
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 5
- 230000002163 immunogen Effects 0.000 title abstract 2
- 239000012634 fragment Substances 0.000 abstract 4
- 229920001184 polypeptide Polymers 0.000 abstract 4
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 4
- 239000008194 pharmaceutical composition Substances 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
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- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
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- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Abstract
La descripción se refiere a métodos para identificar fragmentos de un polipéptido que son inmunogénicos para un sujeto humano específico, métodos para preparar composiciones farmacéuticas personalizadas que comprenden dichos fragmentos de polipéptido, composiciones farmacéuticas específicas para un sujeto humano que comprenden dichos fragmentos de polipéptido y métodos de tratamiento que utilizan dichas composiciones. Los métodos comprenden identificar un fragmento del polipéptido que se une a múltiples HLA del sujeto.
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PCT/EP2018/055231 WO2018158456A1 (en) | 2017-03-03 | 2018-03-02 | Personalised immunogenic peptide identification platform |
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CONC2019/0010503A CO2019010503A2 (es) | 2017-03-03 | 2019-09-26 | Plataforma de identificación de péptidos inmunogénicos personalizada |
CONC2019/0010698A CO2019010698A2 (es) | 2017-03-03 | 2019-09-27 | Vacunas de peptidos |
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