MA25403A1 - Ligandes de recepteur de melanocortine - Google Patents
Ligandes de recepteur de melanocortineInfo
- Publication number
- MA25403A1 MA25403A1 MA26340A MA26340A MA25403A1 MA 25403 A1 MA25403 A1 MA 25403A1 MA 26340 A MA26340 A MA 26340A MA 26340 A MA26340 A MA 26340A MA 25403 A1 MA25403 A1 MA 25403A1
- Authority
- MA
- Morocco
- Prior art keywords
- receptor ligands
- melanocortine
- melanocortine receptor
- ligands
- receptor
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/665—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
- C07K14/68—Melanocyte-stimulating hormone [MSH]
- C07K14/685—Alpha-melanotropin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
- A61P5/40—Mineralocorticosteroids, e.g. aldosterone; Drugs increasing or potentiating the activity of mineralocorticosteroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/665—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
- C07K14/68—Melanocyte-stimulating hormone [MSH]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Endocrinology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Neurology (AREA)
- Gastroenterology & Hepatology (AREA)
- Genetics & Genomics (AREA)
- Diabetes (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Reproductive Health (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Gynecology & Obstetrics (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Psychology (AREA)
- Obesity (AREA)
- Pregnancy & Childbirth (AREA)
- Child & Adolescent Psychology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US12667399P | 1999-03-29 | 1999-03-29 |
Publications (1)
Publication Number | Publication Date |
---|---|
MA25403A1 true MA25403A1 (fr) | 2002-04-01 |
Family
ID=22426131
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA26340A MA25403A1 (fr) | 1999-03-29 | 2001-09-26 | Ligandes de recepteur de melanocortine |
Country Status (34)
Country | Link |
---|---|
US (2) | US6613874B1 (fr) |
EP (1) | EP1165613B1 (fr) |
JP (1) | JP2002542159A (fr) |
KR (2) | KR100519201B1 (fr) |
CN (1) | CN1249086C (fr) |
AR (1) | AR023201A1 (fr) |
AT (1) | ATE393783T1 (fr) |
AU (1) | AU763510B2 (fr) |
BR (1) | BR0009497A (fr) |
CA (1) | CA2368431C (fr) |
CO (1) | CO5170531A1 (fr) |
CZ (1) | CZ20013407A3 (fr) |
DE (1) | DE60038734T2 (fr) |
DK (1) | DK1165613T3 (fr) |
ES (1) | ES2304345T3 (fr) |
HK (1) | HK1044954B (fr) |
HU (1) | HUP0202203A3 (fr) |
ID (1) | ID30262A (fr) |
IL (1) | IL145406A0 (fr) |
MA (1) | MA25403A1 (fr) |
MX (1) | MXPA01009881A (fr) |
MY (1) | MY126585A (fr) |
NO (1) | NO20014568L (fr) |
NZ (1) | NZ514141A (fr) |
PE (1) | PE20001641A1 (fr) |
PL (1) | PL350095A1 (fr) |
PT (1) | PT1165613E (fr) |
RU (1) | RU2213098C2 (fr) |
SA (1) | SA00210192B1 (fr) |
SK (1) | SK13082001A3 (fr) |
TR (1) | TR200102765T2 (fr) |
TW (1) | TWI250990B (fr) |
WO (1) | WO2000058361A1 (fr) |
ZA (1) | ZA200107411B (fr) |
Families Citing this family (75)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2002064091A2 (fr) | 2001-02-13 | 2002-08-22 | Palatin Technologies, Inc. | Metallopeptides de melanocortine pour le traitement de dysfonctions sexuelles |
US7192713B1 (en) | 1999-05-18 | 2007-03-20 | President And Fellows Of Harvard College | Stabilized compounds having secondary structure motifs |
EP1187614A4 (fr) | 1999-06-04 | 2005-06-22 | Merck & Co Inc | Piperidines substituees en tant qu'agonistes du recepteur de melanocortine-4 |
US7235625B2 (en) | 1999-06-29 | 2007-06-26 | Palatin Technologies, Inc. | Multiple agent therapy for sexual dysfunction |
EP1251865A1 (fr) | 2000-01-18 | 2002-10-30 | Merck & Co., Inc. | Peptides cycliques utilises comme antagonistes puissants et selectifs du recepteur de la melanocortine-4 |
YU15603A (sh) | 2000-08-30 | 2006-05-25 | F. Hoffmann-La Roche Ag. | Selektivni ciklični peptidi |
KR100519204B1 (ko) * | 2000-09-27 | 2005-10-06 | 더 프록터 앤드 갬블 캄파니 | 멜라노코르틴 수용체 리간드 |
US7342089B2 (en) * | 2001-07-11 | 2008-03-11 | Palatin Technologies, Inc. | Cyclic peptides for treatment for cachexia |
US7345144B2 (en) * | 2001-07-11 | 2008-03-18 | Palatin Technologies, Inc. | Cyclic peptides for treatment of cachexia |
EP1441750A4 (fr) | 2001-07-11 | 2006-10-18 | Palatin Technologies Inc | Peptides lineaires et cycliques specifiques du recepteur de melanocortine |
US20030195187A1 (en) * | 2002-02-04 | 2003-10-16 | Chiron Corporation | Guanidino compounds |
US7034004B2 (en) * | 2002-05-07 | 2006-04-25 | University Of Florida | Peptides and methods for the control of obesity |
US7323462B2 (en) | 2002-12-10 | 2008-01-29 | Pfizer Inc. | Morpholine dopamine agonists |
WO2005000339A2 (fr) * | 2003-06-19 | 2005-01-06 | Eli Lilly And Company | Agonistes du recepteur 4 de la melanocortine (mc4) et utilisations |
WO2005000338A1 (fr) * | 2003-06-19 | 2005-01-06 | Eli Lilly And Company | Utilisation de peptides agonistes du recepteur de la melanocortine-3 (mc3r) |
WO2005030797A2 (fr) * | 2003-09-30 | 2005-04-07 | Novo Nordisk A/S | Nouveaux agonistes du recepteur de la melanocortine |
AU2015201062B2 (en) * | 2003-11-05 | 2017-03-09 | Dana-Farber Cancer Institute, Inc. | Stabilized alpha helical peptides and uses thereof |
EP2332968B1 (fr) | 2003-11-05 | 2016-05-04 | Dana-Farber Cancer Institute, Inc. | Peptides alpha-hélicaux pour l'activation ou l'inhibition de la mort cellulaire |
JP4874811B2 (ja) | 2004-01-21 | 2012-02-15 | ノボ ノルディスク ヘルス ケア アクチェンゲゼルシャフト | ペプチドのトランスグルタミナーゼ媒介性の結合 |
US6974187B2 (en) * | 2004-01-28 | 2005-12-13 | Tachi-S Co., Ltd. | Vehicle seat structure |
EP1732586A1 (fr) * | 2004-03-29 | 2006-12-20 | Eli Lilly And Company | Utilisations de peptides agonistes du recepteur de la melanocortine 4 (mc4r) administres par perfusion continue |
EP1804798A4 (fr) * | 2004-10-05 | 2008-01-23 | Merck & Co Inc | Procedes de traitement d'un abus d'une substance d'une addiction a cette substance |
WO2006060873A1 (fr) * | 2004-12-09 | 2006-06-15 | Prince Henry's Institute Of Medical Research | Procede de restauration de la fonction reproductrice |
WO2006073771A2 (fr) * | 2005-01-05 | 2006-07-13 | Eli Lilly And Company | Peptides d'agonistes mc4r ou mc3r lies au polyethyleneglycol |
WO2006073772A1 (fr) * | 2005-01-05 | 2006-07-13 | Eli Lilly And Company | Peptides agonistes de mc4r ou de mc3r lies a un polyethyleneglycol |
US20070021433A1 (en) | 2005-06-03 | 2007-01-25 | Jian-Qiang Fan | Pharmacological chaperones for treating obesity |
US7754691B1 (en) | 2005-07-07 | 2010-07-13 | Palatin Technologies, Inc. | Linear melanocortin receptor-specific peptides for cachexia |
ES2386862T3 (es) * | 2005-07-08 | 2012-09-03 | Ipsen Pharma | Ligandos de los receptores de la melanocortina |
WO2007008684A2 (fr) | 2005-07-08 | 2007-01-18 | Societe De Conseils De Recherches Et D'applications Scientifiques S.A.S. | Ligands de recepteurs de melanocortine |
WO2007077112A1 (fr) * | 2005-12-30 | 2007-07-12 | F. Hoffmann-La Roche Ag | Procede de synthese de peptides contenant arginine |
CA2688485C (fr) | 2006-06-09 | 2016-01-05 | Action Pharma A/S | Derives de phenyl pyrrole aminoguanidine |
WO2008076904A1 (fr) | 2006-12-14 | 2008-06-26 | Aileron Therapeutics, Inc. | Systèmes de macrocyclisation bis-sulfhydryle |
US7981998B2 (en) | 2006-12-14 | 2011-07-19 | Aileron Therapeutics, Inc. | Bis-sulfhydryl macrocyclization systems |
EP2952522B1 (fr) | 2007-01-31 | 2019-10-30 | Dana-Farber Cancer Institute, Inc. | Peptides p53 stabilisés et leurs utilisations |
CA2678941C (fr) | 2007-02-23 | 2018-11-27 | Aileron Therapeutics, Inc. | Systemes macrocycliques de triazole |
ES2610531T3 (es) * | 2007-03-28 | 2017-04-28 | President And Fellows Of Harvard College | Polipéptidos cosidos |
WO2008147556A2 (fr) * | 2007-05-25 | 2008-12-04 | Ipsen Pharma S.A.S. | Ligands de récepteurs de la mélanocortine modifiés au moyen d'hydantoïne |
CN101980718A (zh) * | 2008-02-08 | 2011-02-23 | 爱勒让治疗公司 | 治疗性的拟肽大环化合物 |
US20110144303A1 (en) * | 2008-04-08 | 2011-06-16 | Aileron Therapeutics, Inc. | Biologically Active Peptidomimetic Macrocycles |
WO2009126292A2 (fr) * | 2008-04-08 | 2009-10-15 | Aileron Therapeutics, Inc. | Macrocycles peptidomimétiques biologiquement actifs |
KR101687037B1 (ko) | 2008-06-09 | 2016-12-15 | 팔라틴 테크놀로지스 인코포레이티드 | 성기능 장애 치료용 멜라노코르틴 수용체-특이적 펩티드 |
UY31877A (es) * | 2008-06-09 | 2010-01-29 | Palatin Technologies Inc | Péptidos específicos de los receptores de melanocortina para el tratamiento de la obesidad / 669 |
WO2010011313A2 (fr) * | 2008-07-23 | 2010-01-28 | President And Fellows Of Harvard College | Ligature de polypeptides agrafés |
CA2737921C (fr) | 2008-09-22 | 2019-01-15 | Aileron Therapeutics, Inc. | Methodes de preparation de compositions de macrocycles peptidomimetiques alpha-helicoidaux purifies ayant des taux faibles de ppm de metal |
AU2010204648B2 (en) | 2009-01-14 | 2016-09-01 | Aileron Therapeutics, Inc. | Peptidomimetic macrocycles |
UY32690A (es) | 2009-06-08 | 2011-01-31 | Astrazeneca Ab | Péptidos específicos para receptores de melanocortina |
EA020959B1 (ru) | 2009-06-08 | 2015-03-31 | Палатин Текнолоджиз, Инк. | Пептиды, специфичные к меланокортиновым рецепторам |
WO2010144341A2 (fr) | 2009-06-08 | 2010-12-16 | Palatin Technologies, Inc. | Peptides spécifiques des récepteurs aux mélanocortines à pont lactame |
JP2012532929A (ja) | 2009-07-13 | 2012-12-20 | プレジデント アンド フェロウズ オブ ハーバード カレッジ | 二機能性のステープリングされたポリペプチドおよびそれらの使用 |
AU2010298338A1 (en) | 2009-09-22 | 2012-04-12 | Aileron Therapeutics, Inc. | Peptidomimetic macrocycles |
WO2011060355A1 (fr) * | 2009-11-16 | 2011-05-19 | Ipsen Pharma S.A.S | Procede de synthese de ac-arg-cyclo(cys-d-ala-his-d-phe-arg-trp-cys)-nh2 |
JP2013511554A (ja) | 2009-11-23 | 2013-04-04 | パラティン テクノロジーズ,インコーポレイテッド | メラノコルチン−1受容体特異的線状ペプチド |
EP2504352B1 (fr) | 2009-11-23 | 2018-11-14 | Palatin Technologies, Inc. | Peptides cycliques spécifiques du récepteur de la mélanocortine-1 |
CN101824415A (zh) * | 2010-03-31 | 2010-09-08 | 华东师范大学 | 黑素皮质1型受体基因的snp及其应用 |
RU2582678C2 (ru) | 2010-08-13 | 2016-04-27 | Эйлерон Терапьютикс, Инк. | Пептидомиметические макроциклы |
US8957026B2 (en) | 2010-09-22 | 2015-02-17 | President And Fellows Of Harvard College | Beta-catenin targeting peptides and uses thereof |
US9018395B2 (en) | 2011-01-27 | 2015-04-28 | Université de Montréal | Pyrazolopyridine and pyrazolopyrimidine derivatives as melanocortin-4 receptor modulators |
US9487562B2 (en) | 2011-06-17 | 2016-11-08 | President And Fellows Of Harvard College | Stabilized polypeptides as regulators of RAB GTPase function |
AR088392A1 (es) | 2011-10-18 | 2014-05-28 | Aileron Therapeutics Inc | Macrociclos peptidomimeticos |
MX362492B (es) | 2012-02-15 | 2019-01-21 | Aileron Therapeutics Inc | Macrociclos peptidomiméticos. |
US8987414B2 (en) | 2012-02-15 | 2015-03-24 | Aileron Therapeutics, Inc. | Triazole-crosslinked and thioether-crosslinked peptidomimetic macrocycles |
PT2920197T (pt) | 2012-09-26 | 2021-06-11 | Harvard College | Péptidos agrafados com bloqueio de prolina e suas utilizações |
AU2013337388B2 (en) | 2012-11-01 | 2018-08-02 | Aileron Therapeutics, Inc. | Disubstituted amino acids and methods of preparation and use thereof |
SG10201913593WA (en) | 2013-03-13 | 2020-02-27 | Harvard College | Stapled and stitched polypeptides and uses thereof |
BR112015031277A2 (pt) | 2013-06-14 | 2017-09-19 | Harvard College | Moduladores do receptor de insulina de polipeptídeos estabilizados, análogos de insulina, composições farmacêuticas compreendendo os referidos polipeptídeos e métodos de preparação e usos dos mesmos |
IL288147B2 (en) | 2014-05-21 | 2024-03-01 | Harvard College | Ras inhibitory peptides and uses thereof |
BR112017005598A2 (pt) | 2014-09-24 | 2017-12-12 | Aileron Therapeutics Inc | macrociclos peptidomiméticos e usos dos mesmos |
AU2015320545C1 (en) | 2014-09-24 | 2020-05-14 | Aileron Therapeutics, Inc. | Peptidomimetic macrocycles and formulations thereof |
KR20170129879A (ko) | 2015-03-20 | 2017-11-27 | 에일러론 테라퓨틱스 인코포레이티드 | 펩티드모방 거대고리 및 이의 용도 |
US10059741B2 (en) | 2015-07-01 | 2018-08-28 | Aileron Therapeutics, Inc. | Peptidomimetic macrocycles |
JP2018528217A (ja) | 2015-09-10 | 2018-09-27 | エルロン・セラピューティクス・インコーポレイテッドAileron Therapeutics,Inc. | Mcl−1のモジュレーターとしてのペプチド模倣大環状分子 |
CN110681362B (zh) * | 2019-09-26 | 2020-09-11 | 浙江大学 | 以羧基和吲哚基为功能基团的混合模式层析介质 |
US11590209B2 (en) | 2020-01-21 | 2023-02-28 | Palatin Technologies, Inc. | Use of bremelanotide in patients with controlled hypertension |
US11932628B2 (en) | 2021-01-04 | 2024-03-19 | Regents Of The University Of Minnesota | Selective small molecule peptidomimetic melanocortin ligands |
IL309104A (en) | 2021-06-21 | 2024-02-01 | Synact Pharma Aps | Salts of phenyl pyrrole aminoguanidine and polymorphs of phenyl pyrrole aminoguanidinium salts |
Family Cites Families (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5462927A (en) | 1985-04-30 | 1995-10-31 | The Administrators Of The Tulane Educational Fund | Peptides aiding nerve regeneration |
DE3851002T2 (de) | 1987-05-22 | 1995-02-02 | University Patents, Inc., Westport, Conn. | Lineare und zyklische Analoge von alpha-MSH-Fragmenten mit ausserordentlicher Wirkung. |
WO1989002897A1 (fr) | 1987-09-24 | 1989-04-06 | The Administrators Of The Tulane Educational Fund | Peptides a usage therapeutique |
ZA908610B (en) | 1989-11-03 | 1991-08-28 | Univ Tulane | Peptides aiding nerve regeneration |
US5352659A (en) | 1991-02-15 | 1994-10-04 | Takeda Chemical Industries | Endothelin analogs and uses thereof |
DK0528312T3 (da) | 1991-08-13 | 1997-12-29 | Takeda Chemical Industries Ltd | Cykliske peptider og anvendelse deraf |
EP0552417B1 (fr) | 1991-11-19 | 1999-07-07 | Takeda Chemical Industries, Ltd. | Peptides cycliques et leurs utilisations |
EP0547317A1 (fr) | 1991-12-19 | 1993-06-23 | Takeda Chemical Industries, Ltd. | Antagonistes d'endothéline |
DE9203901U1 (de) | 1992-03-24 | 1992-07-16 | Croon & Lucke Maschinenfabrik Gmbh, 7947 Mengen | Gestell zum Lagern von flächigen Werkstücken |
US5569741A (en) | 1992-07-27 | 1996-10-29 | Biomeasure, Inc. | Cyclic octapeptide neuromedin B receptor antagonists |
JP3553062B2 (ja) | 1992-07-27 | 2004-08-11 | ジ アドミニストレイターズ オブ ザ トュラン エデュケーショナル ファンド | ニューロメジンb受容体拮抗物質 |
AU673731B2 (en) | 1993-06-03 | 1996-11-21 | Banyu Pharmaceutical Co., Ltd. | Novel endothelin antagonistic peptide |
EP0714909A1 (fr) | 1994-12-01 | 1996-06-05 | Takeda Chemical Industries, Ltd. | Composition pour la prévention et le traitement de maladies de la circulation pulmonaire |
US5731408A (en) * | 1995-04-10 | 1998-03-24 | Arizona Board Of Regents On Behalf Of The University Of Arizona | Peptides having potent antagonist and agonist bioactivities at melanocortin receptors |
US6054556A (en) * | 1995-04-10 | 2000-04-25 | The Arizona Board Of Regents On Behalf Of The University Of Arizona | Melanocortin receptor antagonists and agonists |
CN1183104A (zh) | 1995-04-28 | 1998-05-27 | 武田药品工业株式会社 | Lh-rh受体拮抗剂 |
US5817750A (en) | 1995-08-28 | 1998-10-06 | La Jolla Cancer Research Foundation | Structural mimics of RGD-binding sites |
AU3257297A (en) | 1996-06-11 | 1998-01-07 | Novartis Ag | Combination of a somatostatin analogue and a rapamycin |
EP0967222A4 (fr) | 1996-06-25 | 2001-08-22 | Nisshin Flour Milling Co | Depsipeptides cycliques et medicaments contenant ces composes comme ingredient actif |
US6251861B1 (en) | 1996-06-27 | 2001-06-26 | Takeda Chemical Industries, Ltd. | Treatment of cerebral infarction using cyclic hexapeptides |
US5770380A (en) | 1996-09-13 | 1998-06-23 | University Of Pittsburgh | Synthetic antibody mimics--multiple peptide loops attached to a molecular scaffold |
IT1288388B1 (it) | 1996-11-19 | 1998-09-22 | Angeletti P Ist Richerche Bio | Uso di sostanze che attivano il recettore del cntf ( fattore neurotrofico ciliare) per la preparazione di farmaci per la terapia |
JP2001506996A (ja) | 1996-12-17 | 2001-05-29 | クアドラント ホールディングス ケンブリッジ リミテッド | メラノコルチン受容体3、4又は5の特異結合のためのメラノコルチン誘導体 |
SE9700620D0 (sv) * | 1997-02-21 | 1997-02-21 | Wapharm Ab | Cykliska peptider med selektivitet för MSH-receptor subtyper |
GB9827500D0 (en) | 1998-12-14 | 1999-02-10 | Wapharm Ab | Compounds for control of eating, growth and body weight |
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2000
- 2000-03-21 CA CA002368431A patent/CA2368431C/fr not_active Expired - Fee Related
- 2000-03-21 AT AT00919500T patent/ATE393783T1/de not_active IP Right Cessation
- 2000-03-21 BR BR0009497-8A patent/BR0009497A/pt not_active IP Right Cessation
- 2000-03-21 DE DE60038734T patent/DE60038734T2/de not_active Expired - Fee Related
- 2000-03-21 CN CNB008057540A patent/CN1249086C/zh not_active Expired - Fee Related
- 2000-03-21 ID IDW00200102111A patent/ID30262A/id unknown
- 2000-03-21 AU AU40179/00A patent/AU763510B2/en not_active Ceased
- 2000-03-21 DK DK00919500T patent/DK1165613T3/da active
- 2000-03-21 ES ES00919500T patent/ES2304345T3/es not_active Expired - Lifetime
- 2000-03-21 EP EP00919500A patent/EP1165613B1/fr not_active Expired - Lifetime
- 2000-03-21 HU HU0202203A patent/HUP0202203A3/hu unknown
- 2000-03-21 NZ NZ514141A patent/NZ514141A/xx unknown
- 2000-03-21 TR TR2001/02765T patent/TR200102765T2/xx unknown
- 2000-03-21 WO PCT/US2000/007473 patent/WO2000058361A1/fr not_active Application Discontinuation
- 2000-03-21 SK SK1308-2001A patent/SK13082001A3/sk unknown
- 2000-03-21 PL PL00350095A patent/PL350095A1/xx not_active Application Discontinuation
- 2000-03-21 CZ CZ20013407A patent/CZ20013407A3/cs unknown
- 2000-03-21 JP JP2000608653A patent/JP2002542159A/ja active Pending
- 2000-03-21 PT PT00919500T patent/PT1165613E/pt unknown
- 2000-03-21 KR KR10-2001-7012436A patent/KR100519201B1/ko not_active IP Right Cessation
- 2000-03-21 MX MXPA01009881A patent/MXPA01009881A/es active IP Right Grant
- 2000-03-21 IL IL14540600A patent/IL145406A0/xx unknown
- 2000-03-21 KR KR1020047019303A patent/KR100558131B1/ko not_active IP Right Cessation
- 2000-03-21 RU RU2001128890/04A patent/RU2213098C2/ru not_active IP Right Cessation
- 2000-03-27 MY MYPI20001220A patent/MY126585A/en unknown
- 2000-03-28 TW TW089105726A patent/TWI250990B/zh not_active IP Right Cessation
- 2000-03-28 CO CO00022068A patent/CO5170531A1/es not_active Application Discontinuation
- 2000-03-29 US US09/537,789 patent/US6613874B1/en not_active Expired - Fee Related
- 2000-03-29 AR ARP000101405A patent/AR023201A1/es active IP Right Grant
- 2000-03-29 PE PE2000000267A patent/PE20001641A1/es not_active Application Discontinuation
- 2000-06-26 SA SA00210192A patent/SA00210192B1/ar unknown
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2001
- 2001-09-07 ZA ZA200107411A patent/ZA200107411B/xx unknown
- 2001-09-20 NO NO20014568A patent/NO20014568L/no not_active Application Discontinuation
- 2001-09-26 MA MA26340A patent/MA25403A1/fr unknown
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2002
- 2002-06-24 HK HK02104687.8A patent/HK1044954B/zh not_active IP Right Cessation
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2003
- 2003-07-02 US US10/612,104 patent/US6951916B2/en not_active Expired - Fee Related
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