MA23837A1 - Benzamides pour le traitement de degenerescenses neurologiques - Google Patents

Benzamides pour le traitement de degenerescenses neurologiques

Info

Publication number: MA23837A1
Authority: MA; Morocco
Prior art keywords: degeneres; benzamides; neurological; treatment; neurological degeneres
Prior art date: 1995-04-03

Application number

MA24193A

Other languages

English (en)

Inventor

D Filter W

L Wilcox A

A Garland W

E Raylod R

Original Assignee

Centaur Pharmaceuticals Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-04-03

Filing date

1996-04-01

Publication date

1996-12-31

1995-04-03 Priority claimed from US08/415,248 external-priority patent/US5659082A/en

1995-04-03 Priority claimed from US08/415,694 external-priority patent/US5658953A/en

1995-04-03 Priority claimed from US08/415,847 external-priority patent/US5643965A/en

1996-04-01 Application filed by Centaur Pharmaceuticals Inc filed Critical Centaur Pharmaceuticals Inc

1996-12-31 Publication of MA23837A1 publication Critical patent/MA23837A1/fr

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
- C07C237/38—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having the nitrogen atom of the carboxamide group bound to a carbon atom of a ring other than a six-membered aromatic ring
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/166—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/64—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings
- C07C233/65—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
- C07C237/30—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having the nitrogen atom of the carboxamide group bound to hydrogen atoms or to acyclic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
- C07C237/42—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/02—Systems containing only non-condensed rings with a three-membered ring

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Epidemiology (AREA)
Psychology (AREA)
Hospice & Palliative Care (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

MA24193A 1995-04-03 1996-04-01 Benzamides pour le traitement de degenerescenses neurologiques MA23837A1 (fr)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
US41567795A	1995-04-03	1995-04-03
US08/415,248 US5659082A (en)	1995-04-03	1995-04-03	Nitro- and aminobenzamide compounds for neurodegenerative disorders
US08/415,694 US5658953A (en)	1995-04-03	1995-04-03	Pharmaceutical compositions of acetamidobenzamide compounds for neurodegenerative disorders
US08/415,847 US5643965A (en)	1995-04-03	1995-04-03	Aminobenzamide compounds for the treatment of neurodegenerative disorders

Publications (1)

Publication Number	Publication Date
MA23837A1 true MA23837A1 (fr)	1996-12-31

Family

ID=27503636

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
MA24193A MA23837A1 (fr)	1995-04-03	1996-04-01	Benzamides pour le traitement de degenerescenses neurologiques

Country Status (39)

Country	Link
EP (1)	EP0819113B1 (fr)
JP (1)	JP3479658B2 (fr)
KR (1)	KR100429120B1 (fr)
CN (1)	CN1073552C (fr)
AR (1)	AR002978A1 (fr)
AT (1)	ATE202552T1 (fr)
AU (1)	AU721045B2 (fr)
BG (1)	BG63384B1 (fr)
CA (1)	CA2215166A1 (fr)
CO (1)	CO4700431A1 (fr)
CZ (1)	CZ295852B6 (fr)
DE (1)	DE69613567T2 (fr)
DK (1)	DK0819113T3 (fr)
DZ (1)	DZ2012A1 (fr)
EA (1)	EA002031B1 (fr)
EE (1)	EE03437B1 (fr)
ES (1)	ES2160240T3 (fr)
GR (1)	GR3036466T3 (fr)
HK (1)	HK1016964A1 (fr)
HR (1)	HRP960156B1 (fr)
HU (1)	HUP9801759A3 (fr)
IL (1)	IL117629A (fr)
IS (1)	IS1919B (fr)
MA (1)	MA23837A1 (fr)
MX (1)	MX9707596A (fr)
MY (1)	MY121206A (fr)
NO (1)	NO318441B1 (fr)
NZ (1)	NZ306204A (fr)
PL (1)	PL184121B1 (fr)
PT (1)	PT819113E (fr)
RO (1)	RO116190B1 (fr)
SA (1)	SA96160739B1 (fr)
SI (1)	SI0819113T1 (fr)
SK (1)	SK282900B6 (fr)
TN (1)	TNSN96051A1 (fr)
TR (1)	TR199701114T1 (fr)
TW (1)	TW381073B (fr)
WO (1)	WO1996031462A1 (fr)
YU (1)	YU21096A (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0912171A1 (fr) *	1996-04-17	1999-05-06	Centaur Pharmaceuticals, Inc.	Traitement par benzamides de la demence associee a l'infection par le virus du sida (vih-1)
WO1999021543A1 (fr)	1997-10-27	1999-05-06	Sumitomo Pharmaceuticals Co., Ltd.	Derives d'amide
EP1079820A1 (fr) *	1998-05-19	2001-03-07	Centaur Pharmaceuticals, Inc.	Medicament a base de benzamide, destine au traitement des affections inflammatoires de l'intestin
US6271265B1 (en)	1998-05-19	2001-08-07	Centaur Pharmaceuticals, Inc.	Amide therapeutics for the treatment of inflammatory bowel disease
AU3679800A (en) *	1999-04-23	2000-11-10	Sumitomo Pharmaceuticals Company, Limited	Apoptosis inhibitors
CN101817761B (zh) *	2010-01-29	2014-06-25	浙江大学	苯甲酸酯类衍生物及制备方法和应用
JP5850321B2 (ja) *	2010-02-10	2016-02-03	公立大学法人横浜市立大学	神経選択的転写抑制因子ＮＲＳＦに特異的に結合するｍＳｉｎ３Ｂに結合する化合物の利用
WO2014155184A1 (fr) *	2013-03-28	2014-10-02	Rhenovia Pharma	Traitement pour maladie de parkinson
CN115594603A (zh) *	2022-10-09	2023-01-13	湖北师范大学（Cn）	微通道反应器制备n-叔丁基-4-氨基苯甲酰胺的方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IT1069882B (it) *	1975-12-22	1985-03-25	Mallinckrodt Inc	3 5 bis acilammino benzammidi particolarmente utili come agenti di contrasto per raffi x e procedimento per la loro preparazione
JPS5721320A (en) *	1980-07-11	1982-02-04	Chugai Pharmaceut Co Ltd	Blood sugar level depressing agent
JPS5867657A (ja) *	1981-10-15	1983-04-22	Chugai Pharmaceut Co Ltd	ペンズアミド誘導体
US5472983A (en) *	1994-04-14	1995-12-05	Centaur Pharmaceuticals, Inc.	Benzamide-containing pharmaceutical compositions

1996
- 1996-03-24 IL IL11762996A patent/IL117629A/xx active IP Right Grant
- 1996-03-27 DZ DZ960053A patent/DZ2012A1/fr active
- 1996-03-28 AR AR10196396A patent/AR002978A1/es unknown
- 1996-03-28 TW TW085103754A patent/TW381073B/zh active
- 1996-04-01 MA MA24193A patent/MA23837A1/fr unknown
- 1996-04-02 CO CO96016205A patent/CO4700431A1/es unknown
- 1996-04-02 YU YU21096A patent/YU21096A/sh unknown
- 1996-04-03 HR HR960156A patent/HRP960156B1/xx not_active IP Right Cessation
- 1996-04-03 ES ES96911550T patent/ES2160240T3/es not_active Expired - Lifetime
- 1996-04-03 CA CA002215166A patent/CA2215166A1/fr not_active Abandoned
- 1996-04-03 EA EA199700287A patent/EA002031B1/ru not_active IP Right Cessation
- 1996-04-03 PL PL96322625A patent/PL184121B1/pl not_active IP Right Cessation
- 1996-04-03 KR KR1019970706966A patent/KR100429120B1/ko not_active IP Right Cessation
- 1996-04-03 NZ NZ306204A patent/NZ306204A/xx unknown
- 1996-04-03 DE DE69613567T patent/DE69613567T2/de not_active Expired - Fee Related
- 1996-04-03 SK SK1325-97A patent/SK282900B6/sk unknown
- 1996-04-03 TN TNTNSN96051A patent/TNSN96051A1/fr unknown
- 1996-04-03 AT AT96911550T patent/ATE202552T1/de not_active IP Right Cessation
- 1996-04-03 JP JP53043896A patent/JP3479658B2/ja not_active Expired - Fee Related
- 1996-04-03 CN CN96193000A patent/CN1073552C/zh not_active Expired - Fee Related
- 1996-04-03 EP EP96911550A patent/EP0819113B1/fr not_active Expired - Lifetime
- 1996-04-03 TR TR97/01114T patent/TR199701114T1/xx unknown
- 1996-04-03 RO RO97-01826A patent/RO116190B1/ro unknown
- 1996-04-03 CZ CZ19973098A patent/CZ295852B6/cs not_active IP Right Cessation
- 1996-04-03 DK DK96911550T patent/DK0819113T3/da active
- 1996-04-03 SI SI9630313T patent/SI0819113T1/xx unknown
- 1996-04-03 EE EE9700235A patent/EE03437B1/xx not_active IP Right Cessation
- 1996-04-03 HU HU9801759A patent/HUP9801759A3/hu unknown
- 1996-04-03 WO PCT/US1996/004538 patent/WO1996031462A1/fr active IP Right Grant
- 1996-04-03 MY MYPI96001225A patent/MY121206A/en unknown
- 1996-04-03 AU AU54404/96A patent/AU721045B2/en not_active Ceased
- 1996-04-03 PT PT96911550T patent/PT819113E/pt unknown
- 1996-04-15 SA SA96160739A patent/SA96160739B1/ar unknown
1997
- 1997-09-25 IS IS4569A patent/IS1919B/is unknown
- 1997-09-29 BG BG101929A patent/BG63384B1/bg unknown
- 1997-10-02 MX MX9707596A patent/MX9707596A/es not_active IP Right Cessation
- 1997-10-02 NO NO19974569A patent/NO318441B1/no unknown
1998
- 1998-11-18 HK HK98112098A patent/HK1016964A1/xx not_active IP Right Cessation
2001
- 2001-08-30 GR GR20010401321T patent/GR3036466T3/el not_active IP Right Cessation

Also Published As

Publication number	Publication date
HRP960156A2 (en)	1997-10-31
IS1919B (is)	2004-03-15
SK132597A3 (en)	1998-09-09
CN1182416A (zh)	1998-05-20
ATE202552T1 (de)	2001-07-15
GR3036466T3 (en)	2001-11-30
AR002978A1 (es)	1998-05-27
EP0819113B1 (fr)	2001-06-27
AU721045B2 (en)	2000-06-22
HUP9801759A3 (en)	2001-06-28
BG101929A (en)	1998-04-30
SA96160739B1 (ar)	2005-10-15
PT819113E (pt)	2001-10-30
IS4569A (is)	1997-09-25
CA2215166A1 (fr)	1996-10-10
WO1996031462A1 (fr)	1996-10-10
HK1016964A1 (en)	1999-11-12
TNSN96051A1 (fr)	2005-03-15
AU5440496A (en)	1996-10-23
PL184121B1 (pl)	2002-09-30
ES2160240T3 (es)	2001-11-01
TW381073B (en)	2000-02-01
MX9707596A (es)	1998-06-30
EA199700287A1 (ru)	1998-04-30
BG63384B1 (bg)	2001-12-29
EP0819113A1 (fr)	1998-01-21
NO974569D0 (no)	1997-10-02
IL117629A (en)	2000-08-13
CZ309897A3 (cs)	1998-12-16
DK0819113T3 (da)	2001-10-15
KR19980703562A (ko)	1998-11-05
RO116190B1 (ro)	2000-11-30
DZ2012A1 (fr)	2002-07-21
PL322625A1 (en)	1998-02-02
EE03437B1 (et)	2001-06-15
JPH11501319A (ja)	1999-02-02
DE69613567T2 (de)	2002-04-18
CO4700431A1 (es)	1998-12-29
DE69613567D1 (de)	2001-08-02
YU21096A (sh)	1999-03-04
TR199701114T1 (xx)	1998-02-21
MY121206A (en)	2006-01-28
EA002031B1 (ru)	2001-12-24
NO974569L (no)	1997-11-21
JP3479658B2 (ja)	2003-12-15
CZ295852B6 (cs)	2005-11-16
IL117629A0 (en)	1996-07-23
CN1073552C (zh)	2001-10-24
SK282900B6 (sk)	2003-01-09
SI0819113T1 (en)	2001-10-31
NZ306204A (en)	1999-01-28
HUP9801759A2 (hu)	1998-12-28
HRP960156B1 (en)	2002-04-30
EE9700235A (et)	1998-04-15
NO318441B1 (no)	2005-03-21
KR100429120B1 (ko)	2004-08-18

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FR07C0046I2 (fr)	2008-05-09	Beta-l-2'-desoxy-nucleosides pour le traitement de l'hepatite b
NO961483D0 (no)	1996-04-12	Fremgangsmåte for behandling av oljeholdig formasjon
FR12C0077I2 (fr)	2013-08-16	Composition pour le traitement des condylomes génitaux
DE59608738D1 (de)	2002-03-21	Verwendung von epinastin für die behandlung von schmerzen
ZA9610139B (en)	1997-06-17	Treatment of the cns effects of hiv
NO963785D0 (no)	1996-09-10	Fremgangsmåte for behandling av 5HT2B-reseptor-relaterte betingelser
DE69635708D1 (de)	2006-03-30	Tetrandrin zur behandlung von augenentzündungen
EP0673384A4 (fr)	1996-10-09	Polypeptides utiles pour traiter des troubles inflammatoires.
DE69627414D1 (de)	2003-05-22	Zusammensetzung effektiv für die Entfernung von Asphalten
FR2705966B1 (fr)	1995-08-25	Compositions antimousse utiles notamment pour le traitement de troubles gastriques.
EP0761604A3 (fr)	1997-06-25	Agent pour le traitement des eaux
IL119459A0 (en)	1997-01-10	Pharmaceutical agents for the treatment of acute and chronic inflammatory diseases
MA23837A1 (fr)	1996-12-31	Benzamides pour le traitement de degenerescenses neurologiques
FR2694575B1 (fr)	1995-09-29	Procede pour le traitement de revetements en mcralz.
FR2746658B1 (fr)	1998-06-19	Valve de drainage implantable pour le traitement de l'hydrocephalie
FR2758465B1 (fr)	1999-04-09	Composition pour le traitement de l'amiante
EP0828503A4 (fr)	1999-10-13	Traitement destine a inhiber la progression de maladies auto-immunes
FR2694384B1 (fr)	1994-10-28	Traitement de la surface de réfractaires.
DZ1988A1 (fr)	2002-07-20	Thérapie de combinaison pour le traitement de l'hiv.
NO973366D0 (no)	1997-07-21	Fremgangsmåte for behandling av multippel sklerose
FR2658419B1 (fr)	1995-01-27	Medicament pour le traitement de la dermatite.
FR2719240B1 (fr)	1996-06-07	Procédé de traitement des suspensions huileuses.
EP0667157A4 (fr)	1995-11-08	Traitement symptomatique des troubles circulatoires.
FR2751637B1 (fr)	1998-10-02	Cellule d'electrocoagulation pour le traitement d'effluents
MA26908A1 (fr)	2004-12-20	S-methyl-dihydro-ziprasidone pour le traitement de troubles psychiatriques et oculaires