LT3506886T - Labai koncentruoti mažo klampumo masp-2 slopinančių antikūnų preparatai, rinkiniai ir būdai - Google Patents

Labai koncentruoti mažo klampumo masp-2 slopinančių antikūnų preparatai, rinkiniai ir būdai

Info

Publication number: LT3506886T
Authority: LT; Lithuania
Prior art keywords: kits; methods; low viscosity; highly concentrated; inhibitory antibody
Prior art date: 2016-08-31

Application number

LTEPPCT/US2017/049415T

Other languages

English (en)

Inventor

Gregory A. Demopulos

Kenneth M. Ferguson

William Joseph Lambert

John Steven Whitaker

Original Assignee

Omeros Corporation

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2016-08-31

Filing date

2017-08-30

Publication date

2024-09-10

2017-08-30 Application filed by Omeros Corporation filed Critical Omeros Corporation

2024-09-10 Publication of LT3506886T publication Critical patent/LT3506886T/lt

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39591—Stabilisation, fragmentation
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
- C07K2317/53—Hinge
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Epidemiology (AREA)
Organic Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Oil, Petroleum & Natural Gas (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Immunology (AREA)
Dermatology (AREA)
Diabetes (AREA)
Biophysics (AREA)
Hematology (AREA)
Genetics & Genomics (AREA)
Psychiatry (AREA)
Microbiology (AREA)
Mycology (AREA)
Endocrinology (AREA)
Urology & Nephrology (AREA)
Psychology (AREA)
Hospice & Palliative Care (AREA)
Ophthalmology & Optometry (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Medicinal Preparation (AREA)
Peptides Or Proteins (AREA)

LTEPPCT/US2017/049415T 2016-08-31 2017-08-30 Labai koncentruoti mažo klampumo masp-2 slopinančių antikūnų preparatai, rinkiniai ir būdai LT3506886T (lt)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US201662382156P	2016-08-31	2016-08-31
PCT/US2017/049415 WO2018045054A1 (en)	2016-08-31	2017-08-30	Highly concentrated low viscosity masp-2 inhibitory antibody formulations, kits, and methods

Publications (1)

Publication Number	Publication Date
LT3506886T true LT3506886T (lt)	2024-09-10

Family

ID=61301617

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
LTEPPCT/US2017/049415T LT3506886T (lt)	2016-08-31	2017-08-30	Labai koncentruoti mažo klampumo masp-2 slopinančių antikūnų preparatai, rinkiniai ir būdai

Country Status (39)

Country	Link
US (2)	US11628217B2 (lt)
EP (2)	EP3506886B1 (lt)
JP (2)	JP6864747B2 (lt)
KR (2)	KR20190043161A (lt)
CN (3)	CN116327917A (lt)
AR (1)	AR109494A1 (lt)
AU (2)	AU2017321605B2 (lt)
CA (1)	CA3035252C (lt)
CL (1)	CL2019000508A1 (lt)
CO (1)	CO2019002239A2 (lt)
CR (1)	CR20190150A (lt)
CU (1)	CU20190015A7 (lt)
DK (1)	DK3506886T3 (lt)
EA (1)	EA201990598A1 (lt)
EC (1)	ECSP19021312A (lt)
ES (1)	ES2986902T3 (lt)
FI (1)	FI3506886T3 (lt)
GE (1)	GEP20217252B (lt)
HR (1)	HRP20241131T1 (lt)
HU (1)	HUE068084T2 (lt)
IL (1)	IL265071B2 (lt)
JO (1)	JOP20170170B1 (lt)
LT (1)	LT3506886T (lt)
MA (1)	MA46109A (lt)
MX (2)	MX2019002338A (lt)
MY (1)	MY189411A (lt)
PE (1)	PE20190469A1 (lt)
PH (1)	PH12019500365A1 (lt)
PL (1)	PL3506886T3 (lt)
PT (1)	PT3506886T (lt)
RS (1)	RS65845B1 (lt)
SG (2)	SG10202100697PA (lt)
SI (1)	SI3506886T1 (lt)
SM (1)	SMT202400333T1 (lt)
TW (2)	TWI730310B (lt)
UA (1)	UA122733C2 (lt)
UY (1)	UY37391A (lt)
WO (1)	WO2018045054A1 (lt)
ZA (1)	ZA201901891B (lt)

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KR102564616B1 (ko) *	2016-01-05	2023-08-08	유니버시티 오브 레스터	필요로 하는 대상체에서 섬유증의 억제 방법
JOP20170170B1 (ar) *	2016-08-31	2022-09-15	Omeros Corp	صيغ لجسم مضاد تثبيطية لـ masp-2 بتركيز عالي ولزوجة منخفضة وأطقم، وطرق
JOP20190068A1 (ar) *	2016-10-13	2019-04-01	Omeros Corp	طرق لتقليل البول البروتيني في خاضع بشري يعاني من الاعتلال الكلوي a الناتج عن الجلوبيولين المناعي
EP3672994A4 (en) *	2017-08-25	2021-06-02	Omeros Corporation	HIGHLY CONCENTRATED LOW VISCOSITY MASP-2 INHIBITIVE ANTIBODY FORMULATIONS, KITS, AND METHODS FOR TREATING PEOPLE WITH ATYPICAL HEMOLYTIC SYNDROME
CN119350433A (zh)	2018-05-29	2025-01-24	奥默罗斯公司	Masp-2抑制剂和使用方法
AU2020225202B2 (en)	2019-02-18	2023-10-26	Eli Lilly And Company	Therapeutic antibody formulation
WO2021013689A1 (en) *	2019-07-19	2021-01-28	Ichnos Sciences SA	Lyophilized antibody formulation
BR112022010078A2 (pt) *	2019-11-26	2022-12-13	Omeros Corp	Métodos para tratar um sujeito humano sofrendo de síndrome da pneumonia idiopática, de síndrome do vazamento capilar, de sobrecarga de fluído e de síndrome do enxerto a seguir do transplante de célula tronco hematopoiética
US12030853B2 (en)	2019-12-04	2024-07-09	Omeros Corporation	MASP-2 inhibitors and methods of use
IL293588A (en)	2019-12-04	2022-08-01	Omeros Corp	Masp-2 inhibitor compounds, compositions comprising same and uses thereof
BR112022010881A2 (pt)	2019-12-04	2022-08-23	Omeros Corp	Composto, composição farmacêutica, e, método para tratar uma doença ou distúrbio associado a serina protease-2 associada à lectina de ligação ao manan
KR20220110530A (ko)	2019-12-04	2022-08-08	오메로스 코포레이션	Masp-2 억제자 및 사용 방법
IL300245A (en)	2020-07-31	2023-03-01	Alamab Therapeutics Inc	Anti-connexin antibody formulations
IL302213A (en) *	2020-10-22	2023-06-01	Allakos Inc	Anti-siglec-8 antibody formulations
US20240141069A1 (en) *	2021-06-08	2024-05-02	Shanghai Jemincare Pharmaceutical Co., Ltd	Anti-masp-2 antibody and use thereof
US20230265215A1 (en)	2021-12-10	2023-08-24	Omeros Corporation	Therapeutic antibodies that bind to the serine protease domain of masp-2 and uses thereof
US20240228499A1 (en)	2022-11-30	2024-07-11	Omeros Corporation	Masp-2 inhibitors and methods of use
TW202440159A (zh) *	2022-12-29	2024-10-16	大陸商蘇州創勝醫藥集團有限公司	含有治療性抗體的藥物製劑及其用途
US12216123B2 (en)	2023-04-25	2025-02-04	Nuvance Health	Extracellular vesicle derived MASP-2 directed cancer treatment methods
WO2024226573A2 (en) *	2023-04-25	2024-10-31	Nuvance Health	Masp-2 directed cancer treatment methods
CN116712390B (zh) *	2023-08-04	2023-11-14	上海览屹医药科技有限公司	一种高浓度高稳定性的抗体制剂及其制备方法

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US7919094B2 (en)	2004-06-10	2011-04-05	Omeros Corporation	Methods for treating conditions associated with MASP-2 dependent complement activation
US8840893B2 (en)	2004-06-10	2014-09-23	Omeros Corporation	Methods for treating conditions associated with MASP-2 dependent complement activation
WO2007076062A2 (en)	2005-12-21	2007-07-05	Wyeth	Protein formulations with reduced viscosity and uses thereof
PT2488203T (pt)	2009-10-16	2017-03-10	Univ Leicester	Métodos para tratamento de coagulação intravascular disseminada através da inibição da activação do complemento dependente de masp-2
MX355648B (es)	2011-04-08	2018-04-26	Univ Leicester	El uso de un agente inhibidor de masp-2 para tratar condiciones asociadas con la activacion del complemento dependiente de masp-2.
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TWI723339B (zh) *	2011-05-02	2021-04-01	美商千禧製藥公司	抗-α4β7抗體之調配物
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WO2014141149A1 (en)	2013-03-15	2014-09-18	Glaxosmithkline Intellectual Property (No.2) Limited	Formulations with reduced viscosity
RS61351B1 (sr) *	2013-10-17	2021-02-26	Omeros Corp	Postupci za lečenje stanja udruženih sa aktivacijom komplementa zavisnom od masp-2
AU2015310879A1 (en) *	2014-09-03	2017-03-02	Medimmune Limited	Stable anti-IL-4R-alpha antibody formulation
WO2016109822A1 (en)	2014-12-31	2016-07-07	Novelmed Therapeutics, Inc.	Formulation of aglycosylated therapeutic antibodies
BR112018009311A8 (pt)	2015-11-09	2019-02-26	Omeros Corporation E Univ Of Leicester	?método para tratar um sujeito humano sofrendo de tma persistente associada com transplante de célula tronco hematopoiética?
US20170253667A1 (en)	2016-01-05	2017-09-07	University Of Leicester	Methods for inhibiting fibrosis in a subject in need thereof
KR102564616B1 (ko)	2016-01-05	2023-08-08	유니버시티 오브 레스터	필요로 하는 대상체에서 섬유증의 억제 방법
CN109152834A (zh)	2016-03-31	2019-01-04	奥默罗斯公司	抑制有需要的受试者的血管发生的方法
JOP20170170B1 (ar)	2016-08-31	2022-09-15	Omeros Corp	صيغ لجسم مضاد تثبيطية لـ masp-2 بتركيز عالي ولزوجة منخفضة وأطقم، وطرق

2017
- 2017-08-28 JO JOP/2017/0170A patent/JOP20170170B1/ar active
- 2017-08-29 TW TW108111015A patent/TWI730310B/zh active
- 2017-08-29 TW TW106129287A patent/TWI719245B/zh active
- 2017-08-30 IL IL265071A patent/IL265071B2/en unknown
- 2017-08-30 UA UAA201903034A patent/UA122733C2/uk unknown
- 2017-08-30 GE GEAP201715038A patent/GEP20217252B/en unknown
- 2017-08-30 SI SI201731539T patent/SI3506886T1/sl unknown
- 2017-08-30 EA EA201990598A patent/EA201990598A1/ru unknown
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- 2017-08-30 RS RS20240925A patent/RS65845B1/sr unknown
- 2017-08-30 CR CR20190150A patent/CR20190150A/es unknown
- 2017-08-30 CN CN202210971376.1A patent/CN116327917A/zh active Pending
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- 2017-08-30 JP JP2019531596A patent/JP6864747B2/ja active Active
- 2017-08-30 LT LTEPPCT/US2017/049415T patent/LT3506886T/lt unknown
- 2017-08-30 CN CN202210971401.6A patent/CN116327695A/zh active Pending
- 2017-08-30 KR KR1020197008678A patent/KR20190043161A/ko not_active Ceased
- 2017-08-30 PL PL17847485.4T patent/PL3506886T3/pl unknown
- 2017-08-30 HU HUE17847485A patent/HUE068084T2/hu unknown
- 2017-08-30 KR KR1020217035424A patent/KR102444154B1/ko active Active
- 2017-08-30 HR HRP20241131TT patent/HRP20241131T1/hr unknown
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- 2017-08-30 SM SM20240333T patent/SMT202400333T1/it unknown
- 2017-08-30 CN CN201780051640.7A patent/CN109890367B/zh active Active
- 2017-08-30 AU AU2017321605A patent/AU2017321605B2/en active Active
- 2017-08-30 MA MA046109A patent/MA46109A/fr unknown
- 2017-08-30 EP EP24160975.9A patent/EP4438060A3/en active Pending
- 2017-08-30 ES ES17847485T patent/ES2986902T3/es active Active
- 2017-08-30 PE PE2019000408A patent/PE20190469A1/es unknown
- 2017-08-30 WO PCT/US2017/049415 patent/WO2018045054A1/en active Application Filing
- 2017-08-30 FI FIEP17847485.4T patent/FI3506886T3/fi active
- 2017-08-30 MY MYPI2019000424A patent/MY189411A/en unknown
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2019
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2020
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2021
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2023
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Also Published As

Publication number	Publication date
JOP20170170B1 (ar)	2022-09-15
AU2020277135B2 (en)	2023-11-02
ECSP19021312A (es)	2019-04-30
SG10202100697PA (en)	2021-02-25
EP3506886A1 (en)	2019-07-10
KR20190043161A (ko)	2019-04-25
CO2019002239A2 (es)	2019-03-18
CL2019000508A1 (es)	2019-06-28
ES2986902T3 (es)	2024-11-13
IL265071B2 (en)	2023-12-01
MX2023014120A (es)	2023-12-12
CN109890367A (zh)	2019-06-14
UA122733C2 (uk)	2020-12-28
FI3506886T3 (fi)	2024-08-20
BR112019003479A2 (pt)	2019-05-21
JP2019531341A (ja)	2019-10-31
AU2017321605B2 (en)	2020-10-08
US20230226178A1 (en)	2023-07-20
US11628217B2 (en)	2023-04-18
IL265071B1 (en)	2023-08-01
TW201811365A (zh)	2018-04-01
CN116327917A (zh)	2023-06-27
NZ751988A (en)	2021-09-24
TWI730310B (zh)	2021-06-11
CN109890367B (zh)	2022-08-30
KR20210135618A (ko)	2021-11-15
TW201944983A (zh)	2019-12-01
CR20190150A (es)	2019-05-14
PH12019500365A1 (en)	2019-11-04
CN116327695A (zh)	2023-06-27
DK3506886T3 (da)	2024-08-19
SG11201901444PA (en)	2019-03-28
EA201990598A1 (ru)	2019-07-31
JP7197623B2 (ja)	2022-12-27
ZA201901891B (en)	2019-12-18
WO2018045054A1 (en)	2018-03-08
HUE068084T2 (hu)	2024-12-28
CA3035252A1 (en)	2018-03-08
AU2017321605A1 (en)	2019-02-07
MY189411A (en)	2022-02-10
JP6864747B2 (ja)	2021-04-28
SMT202400333T1 (it)	2024-09-16
AR109494A1 (es)	2018-12-12
AU2020277135A1 (en)	2020-12-24
HRP20241131T1 (hr)	2024-11-22
CA3035252C (en)	2021-08-10
KR102444154B1 (ko)	2022-09-16
US20180153988A1 (en)	2018-06-07
SI3506886T1 (sl)	2024-09-30
EP3506886A4 (en)	2019-10-09
MX2019002338A (es)	2019-08-16
CU20190015A7 (es)	2019-11-04
RS65845B1 (sr)	2024-09-30
PE20190469A1 (es)	2019-04-04
IL265071A (lt)	2019-04-30
EP4438060A3 (en)	2024-12-25
EP3506886B1 (en)	2024-05-22
TWI719245B (zh)	2021-02-21
JP2021105033A (ja)	2021-07-26
PL3506886T3 (pl)	2024-12-16
JOP20170170A1 (ar)	2019-01-30
PT3506886T (pt)	2024-08-21
MA46109A (fr)	2019-07-10
EP4438060A2 (en)	2024-10-02
GEP20217252B (en)	2021-05-13
UY37391A (es)	2018-02-28

Publication	Publication Date	Title
ZA201901891B (en)	2019-12-18	Highly concentrated low viscosity masp-2 inhibitory antibody formulations, kits, and methods
IL262497A (en)	2018-12-31	Anti-il-33 antibodies, compositions, methods and uses thereof
HUE048313T2 (hu)	2020-07-28	Anti-TIGIT antitestek, anti-PVRIG antitestek és kombinációik
BR112016018521A2 (pt)	2017-10-17	composição, e, kit.
EP3186277A4 (en)	2018-01-17	Antibodies, compositions, and uses
EP3104865A4 (en)	2017-11-22	Micro-organoids, and methods of making and using the same
IL264161B1 (en)	2025-02-01	TGFB Antibodies, Methods and Uses
WO2015179658A3 (en)	2016-01-21	Anti-gpc3 antibodies and immunoconjugates
EP3492591A4 (en)	2020-04-01	ANTI-B7-H4 ANTIBODIES
GB201617572D0 (en)	2016-11-30	Use, method, kit, composition and antibodies
GB201715769D0 (en)	2017-11-15	Methods, Compositions and uses relating thereto
EP3124569A4 (en)	2017-03-15	Polishing composition, and polishing method using same
GB201715768D0 (en)	2017-11-15	Methods, compositions and uses relating thereto
GB201706349D0 (en)	2017-06-07	Methods, compositions and uses relating thereto
EP3702789A4 (en)	2020-12-23	MICROCHIP
EP3481863A4 (en)	2020-03-11	HUMANIZED ANTI-S100A9 ANTIBODY AND USES THEREOF
PT3545144T (pt)	2021-10-06	Elementos de nó, kits e métodos
GB201616670D0 (en)	2016-11-16	Methods, compositions and uses relating thereto
GB201715770D0 (en)	2017-11-15	Methods, compositions and uses relating thereto
GB201616674D0 (en)	2016-11-16	Methods, compositions and uses relating thereto
GB201616666D0 (en)	2016-11-16	Methods, compositions and uses relating thereto
GB201618515D0 (en)	2016-12-14	Combinations comprising antibodies, uses and methods
GB201620279D0 (en)	2017-01-11	Anti-fPSA scFv, B8H8
AU2016904779A0 (en)	2016-12-08	Antibody
GB201616648D0 (en)	2016-11-16	Methods, compositions and uses relating thereto