KR970000222A - 팩리택셀 유도체의 전구약물 - Google Patents

팩리택셀 유도체의 전구약물

Info

Publication number: KR970000222A
Authority: KR; South Korea
Prior art keywords: patricaxel; prodrugs; derivatives; patricaxel derivatives
Prior art date: 1995-06-06

Application number

KR1019960019825A

Other languages

English (en)

Other versions

KR100375956B1 (ko

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-06-06

Filing date

1996-06-04

Publication date

1997-01-21

1996-06-04 Application filed filed Critical

1997-01-21 Publication of KR970000222A publication Critical patent/KR970000222A/ko

2003-04-21 Application granted granted Critical

2003-04-21 Publication of KR100375956B1 publication Critical patent/KR100375956B1/ko

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
- C07F9/65586—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system at least one of the hetero rings does not contain nitrogen as ring hetero atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/655—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
- C07F9/6551—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a four-membered ring
- C07F9/65512—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a four-membered ring condensed with carbocyclic rings or carbocyclic ring systems

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Epoxy Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

KR1019960019825A 1995-06-06 1996-06-04 팩리택셀유도체의전구약물 KR100375956B1 (ko)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US46924795A	1995-06-06	1995-06-06
US469,247		1995-06-06

Publications (2)

Publication Number	Publication Date
KR970000222A true KR970000222A (ko)	1997-01-21
KR100375956B1 KR100375956B1 (ko)	2003-04-21

Family

ID=23863053

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
KR1019960019825A KR100375956B1 (ko)	1995-06-06	1996-06-04	팩리택셀유도체의전구약물

Country Status (23)

Country	Link
EP (1)	EP0747385B1 (ko)
JP (1)	JPH08337589A (ko)
KR (1)	KR100375956B1 (ko)
CN (1)	CN1066151C (ko)
AR (1)	AR002756A1 (ko)
AT (1)	ATE222259T1 (ko)
AU (1)	AU695959B2 (ko)
CA (1)	CA2176191A1 (ko)
CZ (1)	CZ291516B6 (ko)
DE (1)	DE69622933T2 (ko)
DK (1)	DK0747385T3 (ko)
ES (1)	ES2181824T3 (ko)
HU (1)	HUP9601524A3 (ko)
IL (1)	IL118526A (ko)
MX (1)	MX9601994A (ko)
NO (1)	NO315233B1 (ko)
NZ (1)	NZ286723A (ko)
PL (1)	PL187883B1 (ko)
PT (1)	PT747385E (ko)
RU (1)	RU2162082C2 (ko)
SG (1)	SG72692A1 (ko)
TW (1)	TW354293B (ko)
ZA (1)	ZA964261B (ko)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6395770B1 (en) *	1995-10-26	2002-05-28	Baker Norton Pharmaceuticals, Inc.	Method and compositions for administering taxanes orally to human patients
US6515016B2 (en)	1996-12-02	2003-02-04	Angiotech Pharmaceuticals, Inc.	Composition and methods of paclitaxel for treating psoriasis
US6495579B1 (en)	1996-12-02	2002-12-17	Angiotech Pharmaceuticals, Inc.	Method for treating multiple sclerosis
CN1261275A (zh) *	1997-05-27	2000-07-26	巴克·诺顿药物有限公司	给予病人口服紫杉烷类药物的方法和组合物
US6204257B1 (en)	1998-08-07	2001-03-20	Universtiy Of Kansas	Water soluble prodrugs of hindered alcohols
US6538038B1 (en) *	1999-02-18	2003-03-25	Oxigene, Inc.	Compositions and methods for use in targeting vascular destruction
US6362172B2 (en) *	2000-01-20	2002-03-26	Bristol-Myers Squibb Company	Water soluble prodrugs of azole compounds
PL350315A1 (en)	2000-02-02	2002-12-02	Univ Florida State Res Found	C7 carbonate substituted taxanes as antitumor agents
CO5280224A1 (es)	2000-02-02	2003-05-30	Univ Florida State Res Found	Taxanos sustituidos con ester en c7, utiles como agentes antitumorales y composiciones farmaceuticas que los contienen
US6916942B2 (en)	2000-02-03	2005-07-12	Bristol-Myers Squibb Company	Process for the preparation of C-4 carbonate taxanes
US6750246B1 (en)	2000-02-03	2004-06-15	Bristol-Myers Squibb Company	C-4 carbonate taxanes
US7063977B2 (en)	2001-08-21	2006-06-20	Bristol-Myers Squibb Company	Enzymatic resolution of t-butyl taxane derivatives
KR20030049023A (ko) *	2001-12-13	2003-06-25	주식회사 코오롱	방사선 감작제용 파클리탁셀 유도체
SV2006002036A (es)	2004-03-05	2006-03-16	Univ Florida State Res Found	Taxanos con sustituyente lactiloxilo en el c7
EP2896412A1 (en) *	2005-02-18	2015-07-22	Abraxis BioScience, LLC	Drugs with improved hydrophobicity for incorporation in medical devices
EP3492470A1 (en)	2013-03-15	2019-06-05	Concert Pharmaceuticals, Inc.	Deuterated palbociclib with improved metabolic stability
WO2015009889A1 (en)	2013-07-18	2015-01-22	Concert Pharmaceuticals, Inc.	Deuterated intedanib derivatives and their use for the treatment of proliferative disorders
WO2017087594A1 (en) *	2015-11-19	2017-05-26	Biohaven Pharmaceutical Holding Company Ltd.	Amine prodrugs of pharmaceutical compounds

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA2111527C (en) *	1992-12-24	2000-07-18	Jerzy Golik	Phosphonooxymethyl ethers of taxane derivatives
CA2129288C (en) *	1993-08-17	2000-05-16	Jerzy Golik	Phosphonooxymethyl esters of taxane derivatives

1996
- 1996-04-27 TW TW085105043A patent/TW354293B/zh active
- 1996-05-09 CA CA002176191A patent/CA2176191A1/en not_active Abandoned
- 1996-05-27 ZA ZA9604261A patent/ZA964261B/xx unknown
- 1996-05-27 MX MX9601994A patent/MX9601994A/es not_active IP Right Cessation
- 1996-05-29 CZ CZ19961563A patent/CZ291516B6/cs not_active IP Right Cessation
- 1996-05-31 NO NO19962231A patent/NO315233B1/no not_active Application Discontinuation
- 1996-06-02 IL IL11852696A patent/IL118526A/en not_active IP Right Cessation
- 1996-06-03 AR ARP960102865A patent/AR002756A1/es active IP Right Grant
- 1996-06-03 JP JP8139795A patent/JPH08337589A/ja active Pending
- 1996-06-04 KR KR1019960019825A patent/KR100375956B1/ko not_active IP Right Cessation
- 1996-06-04 NZ NZ286723A patent/NZ286723A/en unknown
- 1996-06-05 ES ES96109044T patent/ES2181824T3/es not_active Expired - Lifetime
- 1996-06-05 PL PL31463796A patent/PL187883B1/pl not_active IP Right Cessation
- 1996-06-05 EP EP96109044A patent/EP0747385B1/en not_active Expired - Lifetime
- 1996-06-05 PT PT96109044T patent/PT747385E/pt unknown
- 1996-06-05 AT AT96109044T patent/ATE222259T1/de not_active IP Right Cessation
- 1996-06-05 AU AU54718/96A patent/AU695959B2/en not_active Ceased
- 1996-06-05 DE DE69622933T patent/DE69622933T2/de not_active Expired - Fee Related
- 1996-06-05 HU HU9601524A patent/HUP9601524A3/hu unknown
- 1996-06-05 RU RU96111012/04A patent/RU2162082C2/ru not_active IP Right Cessation
- 1996-06-05 DK DK96109044T patent/DK0747385T3/da active
- 1996-06-06 SG SG1996009989A patent/SG72692A1/en unknown
- 1996-06-06 CN CN96106851A patent/CN1066151C/zh not_active Expired - Fee Related

Also Published As

Publication number	Publication date
AR002756A1 (es)	1998-04-29
NZ286723A (en)	1998-03-25
IL118526A (en)	2001-05-20
IL118526A0 (en)	1996-10-16
DK0747385T3 (da)	2002-12-16
PT747385E (pt)	2002-11-29
HUP9601524A2 (en)	1997-05-28
ZA964261B (en)	1997-11-27
PL187883B1 (pl)	2004-10-29
HUP9601524A3 (en)	2000-03-28
ES2181824T3 (es)	2003-03-01
DE69622933D1 (de)	2002-09-19
AU5471896A (en)	1996-12-19
NO962231D0 (no)	1996-05-31
CA2176191A1 (en)	1996-12-07
CN1066151C (zh)	2001-05-23
NO962231L (no)	1996-12-09
KR100375956B1 (ko)	2003-04-21
TW354293B (en)	1999-03-11
CZ291516B6 (cs)	2003-03-12
NO315233B1 (no)	2003-08-04
MX9601994A (es)	1997-08-30
AU695959B2 (en)	1998-08-27
HU9601524D0 (en)	1996-07-29
EP0747385B1 (en)	2002-08-14
PL314637A1 (en)	1996-12-09
SG72692A1 (en)	2000-05-23
DE69622933T2 (de)	2003-04-24
CZ156396A3 (en)	1996-12-11
EP0747385A1 (en)	1996-12-11
CN1144805A (zh)	1997-03-12
ATE222259T1 (de)	2002-08-15
JPH08337589A (ja)	1996-12-24
RU2162082C2 (ru)	2001-01-20

Publication	Publication Date	Title
BR9611130A (pt)	1999-03-30	Derivados de 3-aril-5-halógeno-pirona
DE69522717D1 (de)	2001-10-18	Chinazolinderivate
DE69611361D1 (de)	2001-02-01	Chinazolin-derivate
NO974103D0 (no)	1997-09-05	Arylsulfonylaminohydroksamsyre-derivater
DE69610698D1 (de)	2000-11-23	Chinazolin-derivate
BR9507179A (pt)	1997-10-07	Derivados de 3-aril-4-hidróxi-delta3-dihidrotiofena
PT833828E (pt)	2003-02-28	Derivados de rapamicina
BR9611834A (pt)	1999-03-09	Derivados de oximetóxi-3-aril-pirona
ATE199150T1 (de)	2001-02-15	Diphenylmethylenpiperidin-derivate
NO964667D0 (no)	1996-11-05	Purin-6-on-derivater
KR970000222A (ko)	1997-01-21	팩리택셀 유도체의 전구약물
DE69601527D1 (de)	1999-03-25	Pyrrolylbenzimidazol-Derivate
ATA100695A (de)	1998-03-15	Prothrombin-derivate
PT856007E (pt)	2004-09-30	Derivados de ciclopeptidos
DE69627830D1 (de)	2003-06-05	Pyrazol-derivate
DE69628200D1 (de)	2003-06-18	Diarylalkenylamin-derivate
BR9607046A (pt)	1997-12-30	Derivados de 3-pirrolidiliden-2-ona-cefalosporinas
DE59607054D1 (de)	2001-07-19	4-Amino-benzoylguanidin-Derivate
DE59610106D1 (de)	2003-03-13	Fluorbenzylether-Derivate
ATE177102T1 (de)	1999-03-15	Chromanderivate
BR9609723A (pt)	1999-03-16	Derivados da tricetona
DK0843675T3 (da)	2003-02-10	Aza-anthracyclinonderivater
BR9603508A (pt)	1998-05-12	Derivados de alquenil-benzoilguanidina
ATE202088T1 (de)	2001-06-15	4-mercapto-benzoylguanidin-derivate
DE69620514D1 (de)	2002-05-16	5-aminoflavon-derivate

Legal Events

Date	Code	Title	Description
1996-06-04	PA0109	Patent application	Patent event code: PA01091R01D Comment text: Patent Application Patent event date: 19960604
1997-01-21	PG1501	Laying open of application
2000-07-26	A201	Request for examination
2000-07-26	PA0201	Request for examination	Patent event code: PA02012R01D Patent event date: 20000726 Comment text: Request for Examination of Application Patent event code: PA02011R01I Patent event date: 19960604 Comment text: Patent Application
2002-07-26	E902	Notification of reason for refusal
2002-07-26	PE0902	Notice of grounds for rejection	Comment text: Notification of reason for refusal Patent event date: 20020726 Patent event code: PE09021S01D
2003-01-27	E701	Decision to grant or registration of patent right
2003-01-27	PE0701	Decision of registration	Patent event code: PE07011S01D Comment text: Decision to Grant Registration Patent event date: 20030127
2003-02-28	GRNT	Written decision to grant
2003-02-28	PR0701	Registration of establishment	Comment text: Registration of Establishment Patent event date: 20030228 Patent event code: PR07011E01D
2003-02-28	PR1002	Payment of registration fee	Payment date: 20030303 End annual number: 3 Start annual number: 1
2003-04-21	PG1601	Publication of registration
2006-02-23	FPAY	Annual fee payment	Payment date: 20060223 Year of fee payment: 4
2006-02-23	PR1001	Payment of annual fee	Payment date: 20060223 Start annual number: 4 End annual number: 4
2007-03-01	LAPS	Lapse due to unpaid annual fee
2007-03-01	PC1903	Unpaid annual fee	Termination category: Default of registration fee Termination date: 20080110