DK0747385T3 - Prodrugs af paclitaxel-derivater - Google Patents

Prodrugs af paclitaxel-derivater

Info

Publication number: DK0747385T3
Authority: DK; Denmark
Prior art keywords: prodrugs; paclitaxel derivatives; paclitaxel; derivatives
Prior art date: 1995-06-06

Application number

DK96109044T

Other languages

English (en)

Inventor

Dolatrai M Vyas

John F Kadow

Paul M Scola

Original Assignee

Bristol Myers Squibb Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-06-06

Filing date

1996-06-05

Publication date

2002-12-16

1996-06-05 Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co

2002-12-16 Application granted granted Critical

2002-12-16 Publication of DK0747385T3 publication Critical patent/DK0747385T3/da

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
- C07F9/65586—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system at least one of the hetero rings does not contain nitrogen as ring hetero atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/655—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
- C07F9/6551—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a four-membered ring
- C07F9/65512—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a four-membered ring condensed with carbocyclic rings or carbocyclic ring systems

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Epoxy Compounds (AREA)

DK96109044T 1995-06-06 1996-06-05 Prodrugs af paclitaxel-derivater DK0747385T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US46924795A	1995-06-06	1995-06-06

Publications (1)

Publication Number	Publication Date
DK0747385T3 true DK0747385T3 (da)	2002-12-16

Family

ID=23863053

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK96109044T DK0747385T3 (da)	1995-06-06	1996-06-05	Prodrugs af paclitaxel-derivater

Country Status (23)

Country	Link
EP (1)	EP0747385B1 (da)
JP (1)	JPH08337589A (da)
KR (1)	KR100375956B1 (da)
CN (1)	CN1066151C (da)
AR (1)	AR002756A1 (da)
AT (1)	ATE222259T1 (da)
AU (1)	AU695959B2 (da)
CA (1)	CA2176191A1 (da)
CZ (1)	CZ291516B6 (da)
DE (1)	DE69622933T2 (da)
DK (1)	DK0747385T3 (da)
ES (1)	ES2181824T3 (da)
HU (1)	HUP9601524A3 (da)
IL (1)	IL118526A (da)
MX (1)	MX9601994A (da)
NO (1)	NO315233B1 (da)
NZ (1)	NZ286723A (da)
PL (1)	PL187883B1 (da)
PT (1)	PT747385E (da)
RU (1)	RU2162082C2 (da)
SG (1)	SG72692A1 (da)
TW (1)	TW354293B (da)
ZA (1)	ZA964261B (da)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6395770B1 (en) *	1995-10-26	2002-05-28	Baker Norton Pharmaceuticals, Inc.	Method and compositions for administering taxanes orally to human patients
AU7130098A (en) *	1995-10-26	1998-12-30	Baker Norton Pharmaceuticals, Inc.	Method and compositions for administering taxanes orally to human patients
US6515016B2 (en)	1996-12-02	2003-02-04	Angiotech Pharmaceuticals, Inc.	Composition and methods of paclitaxel for treating psoriasis
US6495579B1 (en)	1996-12-02	2002-12-17	Angiotech Pharmaceuticals, Inc.	Method for treating multiple sclerosis
US6204257B1 (en)	1998-08-07	2001-03-20	Universtiy Of Kansas	Water soluble prodrugs of hindered alcohols
AU776511B2 (en) *	1999-02-18	2004-09-09	Baylor University	Compositions and methods for use in targeting vascular destruction
US6362172B2 (en) *	2000-01-20	2002-03-26	Bristol-Myers Squibb Company	Water soluble prodrugs of azole compounds
HUP0200756A3 (en)	2000-02-02	2005-02-28	Univ Florida State Res Found	C7 carbonate substituted taxanes as antitumor agents and pharmaceutical compositions containing them
AR030188A1 (es)	2000-02-02	2003-08-13	Univ Florida State Res Found	Compuestos de taxano sustituidos con esteres en el c7; composiciones farmaceuticas que los contienen y proceso para tratar un sujeto mamifero que sufre de una condicion que responde a los taxanos
US6750246B1 (en)	2000-02-03	2004-06-15	Bristol-Myers Squibb Company	C-4 carbonate taxanes
US6916942B2 (en)	2000-02-03	2005-07-12	Bristol-Myers Squibb Company	Process for the preparation of C-4 carbonate taxanes
US7063977B2 (en)	2001-08-21	2006-06-20	Bristol-Myers Squibb Company	Enzymatic resolution of t-butyl taxane derivatives
KR20030049023A (ko) *	2001-12-13	2003-06-25	주식회사 코오롱	방사선 감작제용 파클리탁셀 유도체
AR048078A1 (es)	2004-03-05	2006-03-29	Univ Florida State Res Found	Taxanos con sustituyente lactiloxilo en el c7
EP3345632A1 (en) *	2005-02-18	2018-07-11	Abraxis BioScience, LLC	Drugs with improved hydrophobicity for incorporation in medical devices
EP3492470A1 (en)	2013-03-15	2019-06-05	Concert Pharmaceuticals, Inc.	Deuterated palbociclib with improved metabolic stability
WO2015009889A1 (en)	2013-07-18	2015-01-22	Concert Pharmaceuticals, Inc.	Deuterated intedanib derivatives and their use for the treatment of proliferative disorders
SG10202112588PA (en) *	2015-11-19	2021-12-30	Biohaven Pharm Holding Co Ltd	Amine prodrugs of pharmaceutical compounds

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
MX9308012A (es) *	1992-12-24	1994-08-31	Bristol Myers Squibb Co	Eteres fosfonooximetilicos de derivados de taxano, solubles en agua y composiciones farmaceuticas que los incluyen.
CA2129288C (en) *	1993-08-17	2000-05-16	Jerzy Golik	Phosphonooxymethyl esters of taxane derivatives

1996
- 1996-04-27 TW TW085105043A patent/TW354293B/zh active
- 1996-05-09 CA CA002176191A patent/CA2176191A1/en not_active Abandoned
- 1996-05-27 MX MX9601994A patent/MX9601994A/es not_active IP Right Cessation
- 1996-05-27 ZA ZA9604261A patent/ZA964261B/xx unknown
- 1996-05-29 CZ CZ19961563A patent/CZ291516B6/cs not_active IP Right Cessation
- 1996-05-31 NO NO19962231A patent/NO315233B1/no not_active Application Discontinuation
- 1996-06-02 IL IL11852696A patent/IL118526A/en not_active IP Right Cessation
- 1996-06-03 AR ARP960102865A patent/AR002756A1/es active IP Right Grant
- 1996-06-03 JP JP8139795A patent/JPH08337589A/ja active Pending
- 1996-06-04 KR KR1019960019825A patent/KR100375956B1/ko not_active IP Right Cessation
- 1996-06-04 NZ NZ286723A patent/NZ286723A/en unknown
- 1996-06-05 EP EP96109044A patent/EP0747385B1/en not_active Expired - Lifetime
- 1996-06-05 HU HU9601524A patent/HUP9601524A3/hu unknown
- 1996-06-05 PT PT96109044T patent/PT747385E/pt unknown
- 1996-06-05 AT AT96109044T patent/ATE222259T1/de not_active IP Right Cessation
- 1996-06-05 ES ES96109044T patent/ES2181824T3/es not_active Expired - Lifetime
- 1996-06-05 DK DK96109044T patent/DK0747385T3/da active
- 1996-06-05 RU RU96111012/04A patent/RU2162082C2/ru not_active IP Right Cessation
- 1996-06-05 AU AU54718/96A patent/AU695959B2/en not_active Ceased
- 1996-06-05 DE DE69622933T patent/DE69622933T2/de not_active Expired - Fee Related
- 1996-06-05 PL PL31463796A patent/PL187883B1/pl not_active IP Right Cessation
- 1996-06-06 SG SG1996009989A patent/SG72692A1/en unknown
- 1996-06-06 CN CN96106851A patent/CN1066151C/zh not_active Expired - Fee Related

Also Published As

Publication number	Publication date
JPH08337589A (ja)	1996-12-24
PL314637A1 (en)	1996-12-09
CA2176191A1 (en)	1996-12-07
ZA964261B (en)	1997-11-27
EP0747385A1 (en)	1996-12-11
ATE222259T1 (de)	2002-08-15
RU2162082C2 (ru)	2001-01-20
CZ156396A3 (en)	1996-12-11
IL118526A0 (en)	1996-10-16
CZ291516B6 (cs)	2003-03-12
NO962231L (no)	1996-12-09
PL187883B1 (pl)	2004-10-29
NO315233B1 (no)	2003-08-04
KR100375956B1 (ko)	2003-04-21
TW354293B (en)	1999-03-11
AU5471896A (en)	1996-12-19
NO962231D0 (no)	1996-05-31
SG72692A1 (en)	2000-05-23
HU9601524D0 (en)	1996-07-29
AR002756A1 (es)	1998-04-29
HUP9601524A2 (en)	1997-05-28
EP0747385B1 (en)	2002-08-14
ES2181824T3 (es)	2003-03-01
PT747385E (pt)	2002-11-29
DE69622933D1 (de)	2002-09-19
NZ286723A (en)	1998-03-25
CN1144805A (zh)	1997-03-12
KR970000222A (ko)	1997-01-21
HUP9601524A3 (en)	2000-03-28
IL118526A (en)	2001-05-20
DE69622933T2 (de)	2003-04-24
AU695959B2 (en)	1998-08-27
CN1066151C (zh)	2001-05-23
MX9601994A (es)	1997-08-30

Publication	Publication Date	Title
DK0747385T3 (da)	2002-12-16	Prodrugs af paclitaxel-derivater
DK0851855T3 (da)	2002-09-23	Derivater af melatonin deraf som lægemiddel
DK0833828T3 (da)	2003-03-17	Rapamycinderivater
DK0977748T3 (da)	2003-07-21	Substituerede benzopyranderivater tilbehandling af inflammation
BR9611130A (pt)	1999-03-30	Derivados de 3-aril-5-halógeno-pirona
DE69611361D1 (de)	2001-02-01	Chinazolin-derivate
DE69522717D1 (de)	2001-10-18	Chinazolinderivate
DE69610698D1 (de)	2000-11-23	Chinazolin-derivate
ATE199150T1 (de)	2001-02-15	Diphenylmethylenpiperidin-derivate
NO964667D0 (no)	1996-11-05	Purin-6-on-derivater
DE69601527D1 (de)	1999-03-25	Pyrrolylbenzimidazol-Derivate
ATA100695A (de)	1998-03-15	Prothrombin-derivate
ATE224891T1 (de)	2002-10-15	Chromon-derivate
ATE240307T1 (de)	2003-05-15	Diarylalkenylamin-derivate
DE69627830D1 (de)	2003-06-05	Pyrazol-derivate
BR9607046A (pt)	1997-12-30	Derivados de 3-pirrolidiliden-2-ona-cefalosporinas
DE59607054D1 (de)	2001-07-19	4-Amino-benzoylguanidin-Derivate
ATE177102T1 (de)	1999-03-15	Chromanderivate
DE59610106D1 (de)	2003-03-13	Fluorbenzylether-Derivate
DK0681580T3 (da)	1997-08-18	Prolægemidler af anti-inflammatoriske 3-acyl-2-oxindol-1-carboxamider
BR9609723A (pt)	1999-03-16	Derivados da tricetona
DE69624122D1 (de)	2002-11-07	Aza-anthracyclinone-derivate
ATE202088T1 (de)	2001-06-15	4-mercapto-benzoylguanidin-derivate
DK0847400T3 (da)	2002-03-25	Polymorfer af prolægemidlet 6-N-(L-ALA-L-ALA)-trovafloxacin
DE69620514D1 (de)	2002-05-16	5-aminoflavon-derivate