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KR940021079A - 항독소제를 함유하는 안과용 렌즈 - Google Patents

항독소제를 함유하는 안과용 렌즈 Download PDF

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Publication number
KR940021079A
KR940021079A KR1019940003948A KR19940003948A KR940021079A KR 940021079 A KR940021079 A KR 940021079A KR 1019940003948 A KR1019940003948 A KR 1019940003948A KR 19940003948 A KR19940003948 A KR 19940003948A KR 940021079 A KR940021079 A KR 940021079A
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South Korea
Prior art keywords
lens
ester
glyceryl
present
toxins
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KR1019940003948A
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Inventor
지. 반더란 더글라스
케이. 브라운-스크로버트 수잔
엘. 슐츠 클라이드
Original Assignee
로버트 엘. 조카
존슨 앤드 존슨 비젼 프로덕츠, 인코포레이티드
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Publication of KR940021079A publication Critical patent/KR940021079A/ko
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L12/00—Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor
    • A61L12/08—Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor using chemical substances
    • A61L12/14—Organic compounds not covered by groups A61L12/10 or A61L12/12
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B1/00—Optical elements characterised by the material of which they are made; Optical coatings for optical elements
    • G02B1/04—Optical elements characterised by the material of which they are made; Optical coatings for optical elements made of organic materials, e.g. plastics
    • G02B1/041—Lenses
    • G02B1/043—Contact lenses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/14—Eye parts, e.g. lenses or corneal implants; Artificial eyes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28—Materials for coating prostheses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/216—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials with other specific functional groups, e.g. aldehydes, ketones, phenols, quaternary phosphonium groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/22—Lipids, fatty acids, e.g. prostaglandins, oils, fats, waxes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/16—Materials or treatment for tissue regeneration for reconstruction of eye parts, e.g. intraocular lens, cornea

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Physics & Mathematics (AREA)
  • Transplantation (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Biomedical Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Cardiology (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Materials For Medical Uses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Eyeglasses (AREA)
  • Prostheses (AREA)
  • Medicinal Preparation (AREA)
  • Optical Filters (AREA)
  • Apparatus For Disinfection Or Sterilisation (AREA)

Abstract

본 발명은 눈의 앞면에 착용하는 안과용 렌즈에 관한 것이다. 알콜 잔기가 하나 이상의 하이드록실 그룹을 갖는 다가 지방족 알콜과 지방산의 에스테르에 렌즈를 함침시키거나 렌즈 표면에 이를 피복한다. 에스테르는 렌즈를 이들 독소에 노출시킬 때 세균성 독소의 방출을 방지하거나 감소시키기에 효과적인 양으로 존재한다. 렌즈는 연질 하이드로겔 콘택트 렌즈가 특히 적합하고 유리하게는 각막염을 제거, 최소화 또는 방지한다. 세균성 각막염은 눈의 각막에 감염되는데, 이는 렌즈를 오래 착용하면 발생되고 각막의 궤양을 유발시킨다.

Description

항독소제를 함유하는 안과용 렌즈
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (18)

  1. 다가 지방족 알콜과 지방산의 에스테르[여기서, 에스테르는, 렌즈를 독소에 노출시킬 때, 세균성 독소의 방출을 방지하거나 감소시키는데 효과적인 양으로 존재하고, 다가 지방족 알콜과 탄소수가 8 내지 18인 지방산의 모노에스테르(여기서, 모노에스테르는 이의 지방족 알콜 잔기와 관련된 하나 이상의 하이드록실 그룹을 갖는다) (a) 다가 지방족 알콜과 탄소수가 8 내지 18인 지방산의 디에스테르(여기서, 디에스테르는 이의 지방족 알콜 잔기와 관련된 하나 이상의 하이드록실 그룹을 갖는다) (b) 및 모노에스테르와 디에스테르의 혼합물 (c)로 이루어진 그룹중에서 선택된다]를 표면에 침투시키거나 피복시킴을 특징으로 하는, 눈의 앞면에 착용하는 안과용 렌즈.
  2. 제1항에 있어서, 콘택트 렌즈 또는 각막 밴디지 렌즈인 렌즈.
  3. 제2항에 있어서, 콘택트 렌즈인 렌즈.
  4. 제3항에 있어서, 콘택트 렌즈가 연질 하이드로겔 콘택트 렌즈인 렌즈.
  5. 제4항에 있어서, 에스테르가 침투된 렌즈.
  6. 제5항에 있어서, 에스테르가 렌즈의 중량을 기준으로 약 0.05 내지 약 5.0중량%의 양으로 존재하는 렌즈.
  7. 제6항에 있어서, 에스테르가 약 0.5 내지 약 1.0중량%의 양으로 존재하는 렌즈.
  8. 제7항에 있어서, 지방산이 라우르산인 렌즈.
  9. 제8항에 있어서, 다가 알콜이 글리세롤인 렌즈.
  10. 제9항에 있어서, 에스테르가 글리세릴 모노라우레이트인 렌즈.
  11. 제7항에 있어서, 에스테르가 글리세릴 모노라우레이트와 글리세릴 디라우레이트의 혼합물을 포함하는 렌즈.
  12. 제7항에 있어서, 에스테르가 글리세릴 모노카프릴레이트인 렌즈.
  13. 제7항에 있어서, 에스테르가 글리세릴 카프레이트인 렌즈.
  14. 제7항에 있어서, 에스테르가 글리세릴 모노카프릴레이트와 글리세릴 카프레이트의 혼합물을 포함하는 렌즈.
  15. 제7항에 있어서, 에스테르가 글리세릴 모노미리스테이트인 렌즈.
  16. 제7항에 있어서, 에스테르가 글리세릴 모노팔미테이트인 렌즈.
  17. 제7항에 있어서, 에스테르가 글리세릴 모노스테아레이트인 렌즈.
  18. 제7항에 있어서, 에스테르가 글리세릴 모노올레이트인 렌즈.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019940003948A 1993-03-02 1994-03-02 항독소제를 함유하는 안과용 렌즈 Withdrawn KR940021079A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/025,018 1993-03-02
US08/025,018 US5472703A (en) 1993-03-02 1993-03-02 Ophthalmic lens with anti-toxin agent

Publications (1)

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KR940021079A true KR940021079A (ko) 1994-10-17

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Country Link
US (1) US5472703A (ko)
EP (1) EP0613694B1 (ko)
JP (1) JP3390999B2 (ko)
KR (1) KR940021079A (ko)
CN (1) CN1099605C (ko)
AT (1) ATE171077T1 (ko)
AU (1) AU675101B2 (ko)
BR (1) BR9400787A (ko)
CA (1) CA2116834A1 (ko)
CZ (1) CZ46194A3 (ko)
DE (1) DE69413271T2 (ko)
ES (1) ES2122163T3 (ko)
FI (1) FI940976L (ko)
GR (1) GR1002257B (ko)
GT (1) GT199400014A (ko)
HU (1) HU214060B (ko)
IL (1) IL108820A (ko)
NO (1) NO940707L (ko)
NZ (1) NZ260004A (ko)
PH (1) PH31000A (ko)
RU (1) RU94007090A (ko)
SG (1) SG63541A1 (ko)
TW (1) TW289094B (ko)
UY (1) UY23735A1 (ko)
ZA (1) ZA941430B (ko)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20210093609A (ko) 2020-01-20 2021-07-28 이원계 승용차의 창을 통해 내부로 유입되는 공기배출시스템
KR20220152722A (ko) 2021-05-10 2022-11-17 이원계 주행 중 승용차의 측면창을 통해 내부로 유입되는 공기배출시스템
KR20240146355A (ko) 2023-03-29 2024-10-08 이원계 승용차의 회전판 배기도어

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Cited By (3)

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Publication number Priority date Publication date Assignee Title
KR20210093609A (ko) 2020-01-20 2021-07-28 이원계 승용차의 창을 통해 내부로 유입되는 공기배출시스템
KR20220152722A (ko) 2021-05-10 2022-11-17 이원계 주행 중 승용차의 측면창을 통해 내부로 유입되는 공기배출시스템
KR20240146355A (ko) 2023-03-29 2024-10-08 이원계 승용차의 회전판 배기도어

Also Published As

Publication number Publication date
BR9400787A (pt) 1994-11-22
ZA941430B (en) 1995-09-01
CZ46194A3 (en) 1994-10-19
HU214060B (en) 1997-12-29
JPH06343686A (ja) 1994-12-20
FI940976A0 (fi) 1994-03-01
FI940976L (fi) 1994-09-03
NO940707D0 (no) 1994-03-01
SG63541A1 (en) 1999-03-30
NZ260004A (en) 1995-12-21
RU94007090A (ru) 1996-08-20
JP3390999B2 (ja) 2003-03-31
DE69413271D1 (de) 1998-10-22
PH31000A (en) 1997-12-23
AU675101B2 (en) 1997-01-23
AU5649394A (en) 1994-09-08
HU9400618D0 (en) 1994-05-30
NO940707L (no) 1994-09-05
TW289094B (ko) 1996-10-21
IL108820A (en) 1997-02-18
CN1099605C (zh) 2003-01-22
ATE171077T1 (de) 1998-10-15
HUT67519A (en) 1995-04-28
GR1002257B (en) 1996-04-23
CA2116834A1 (en) 1994-09-03
EP0613694A1 (en) 1994-09-07
EP0613694B1 (en) 1998-09-16
IL108820A0 (en) 1994-06-24
CN1101722A (zh) 1995-04-19
ES2122163T3 (es) 1998-12-16
UY23735A1 (es) 1994-06-16
GT199400014A (es) 1995-08-23
US5472703A (en) 1995-12-05
DE69413271T2 (de) 1999-04-08

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