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KR930700179A - 이온 영동 전달 장치 - Google Patents

이온 영동 전달 장치

Info

Publication number
KR930700179A
KR930700179A KR1019920702367A KR920702367A KR930700179A KR 930700179 A KR930700179 A KR 930700179A KR 1019920702367 A KR1019920702367 A KR 1019920702367A KR 920702367 A KR920702367 A KR 920702367A KR 930700179 A KR930700179 A KR 930700179A
Authority
KR
South Korea
Prior art keywords
reservoir
counter electrode
drug
electrolyte
conductive filler
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
KR1019920702367A
Other languages
English (en)
Other versions
KR0159909B1 (ko
Inventor
패트릭 제이. 류
제이 리챠드 죠리
Original Assignee
에드워드 엘.맨델
앨자 코포레이션
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 에드워드 엘.맨델, 앨자 코포레이션 filed Critical 에드워드 엘.맨델
Publication of KR930700179A publication Critical patent/KR930700179A/ko
Application granted granted Critical
Publication of KR0159909B1 publication Critical patent/KR0159909B1/ko
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/20—Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30—Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0448—Drug reservoir
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0432—Anode and cathode
    • A61N1/0436—Material of the electrode

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Electrotherapy Devices (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • External Artificial Organs (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Conductive Materials (AREA)
  • Inks, Pencil-Leads, Or Crayons (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

내용 없음.

Description

이온 영동 전달 장치
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
제1도는 본 발명의 이온 영동 약물 전달 장치의 개요도,
제2도는 본 발명의 이온 영동 전달 장치의 또다른 실시태양의 개요도이고,
제3도는 실시예 Ⅱ에 기재된 전극 어셈블리에 있어서 시간의 경과에 따른 전류밀도의 그래프이다.

Claims (22)

  1. 약제를 함유하고 신체 표면에 약제를 전달하도록 놓여진 약제 저장기를 포함하는 공여 전극 어셈블리, 대항 전극 어셈블리, 및 공여 전극 어셈블리 및 대항 전극 어셈블리에 전기적으로 연결되는 전기 동력원을 포함하며, 공여 전극이 전기 동력원에 전기적으로 연결되고, 약제 저장기와 접촉하는 표면을 갖는, 전기 동력 이온 영동 약제 전달 장치로서 약제 저장기가 친수성 중합체 약 10 내지 60중량%, 소수성 중합체 약 10 내지 60중량% 및 약제 약 50중량% 이하로 이루어짐을 특징으로 하는 전기 동력 이온 영동 약제 전달 장치.
  2. 제1항에 있어서, 공여 전극이 금속 호일로 이루어지는 장치.
  3. 제2항에 있어서, 금속이 은 및 아연으로 이루어지는 군 중에서 선택되는 장치.
  4. 제1항에 있어서, 공여 전극이 전도성 충진제를 함유하는 소수성 중합체 매트리스로 이루어지는 장치.
  5. 제4항에 있어서, 전도성 충진제가 금속 입자로 이루어지는 장치.
  6. 제4항에 있어서, 전도성 충진제가 탄소 섬유로 이루어지는 장치.
  7. 제1항에 있어서, 소수성 중합체가 에틸렌 비닐 아세테이트 공중합체로 이루어지는 장치.
  8. 제1항에 있어서, 친수성 중합체가 폴리비닐피롤리돈으로 이루어지는 장치.
  9. 제4항에 있어서, 약제 저장기 및 공여 전극 각각이 필름 형태인 장치.
  10. 제9항에 있어서, 공여 전극 및 약제 저장기가 서로 라미네이트된 장치.
  11. 제10항에 있어서, 라미네이트된 필름이 이온 전도성 접착제로 서로 접착된 장치.
  12. 제1항에 있어서, 대항 전극 어셈블리가, 전기 동력원에 전기적으로 연결되며 전해질 저장기에 접촉하는 표면을 갖는 대항 전극 및 신체 표면에 전해질을 전달하도록 놓여지는 전해질 저장기를 포함하며 전해질 저장기는 친수성 중합체 약 10 내지 60중량%, 소수성 중합체 약 10 내지 60중량% 및 전해질 약 50중량% 이하로 이루어지는 장치.
  13. 제12항에 있어서, 대항 전극이 금속 호일로 이루어지는 장치.
  14. 제13항에 있어서, 금속이 은 및 아연으로 이루어지는 군 중에서 선택되는 장치.
  15. 제12항에 있어서, 대항 전극이 전도성 충진제를 함유하는 소수성 중합체로 이루어지는 장치.
  16. 제15항에 있어서, 전도성 충진제가 금속 입자로 이루어지는 장치.
  17. 제15항에 있어서, 전도성 충진제가 탄소 섬유로 이루어지는 장치.
  18. 제12항에 있어서, 전해질 저장기 중의 소수성 중합체가 에틸렌 비닐 아세테이트 공중합체로 이루어지는 장치.
  19. 제12항에 있어서, 전해질 저장기 중의 친수성 중합체가 폴리비닐피롤리돈으로 이루어지는 장치.
  20. 제15항에 있어서, 대항 전극 및 전해질 저장기 각각이 필름 형태인 장치.
  21. 제20항에 있어서, 대항 전극 및 전해질 저장기가 서로 라미네이트된 장치.
  22. 제22항에 있어서, 라미네이트된 필름이 이온 전도성 접착제로 서로 접착된 장치.
    ※ 참고사항 : 최초출원 내용에 의하여 공개되는 것임.
KR1019920702367A 1990-03-30 1991-03-25 이온 영동 전달 장치 Expired - Lifetime KR0159909B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US07/502,608 US5084006A (en) 1990-03-30 1990-03-30 Iontopheretic delivery device
US502,608 1990-03-30
PCT/US1991/001975 WO1991015259A1 (en) 1990-03-30 1991-03-25 Iontophoretic delivery device

Publications (2)

Publication Number Publication Date
KR930700179A true KR930700179A (ko) 1993-03-13
KR0159909B1 KR0159909B1 (ko) 1999-02-18

Family

ID=23998583

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019920702367A Expired - Lifetime KR0159909B1 (ko) 1990-03-30 1991-03-25 이온 영동 전달 장치

Country Status (18)

Country Link
US (2) US5084006A (ko)
EP (1) EP0522011B1 (ko)
JP (1) JP2924922B2 (ko)
KR (1) KR0159909B1 (ko)
AT (1) ATE107866T1 (ko)
AU (1) AU636744B2 (ko)
CA (1) CA2038968C (ko)
DE (1) DE69102699T2 (ko)
DK (1) DK0522011T3 (ko)
ES (1) ES2056646T3 (ko)
FI (1) FI924343A0 (ko)
IE (1) IE64973B1 (ko)
MX (1) MX172532B (ko)
NO (1) NO923591L (ko)
NZ (1) NZ237560A (ko)
PT (1) PT97140B (ko)
WO (1) WO1991015259A1 (ko)
ZA (1) ZA912227B (ko)

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