ATE373957T1 - Verfahren und vorrichtung zur transdermalen verabreichung von lithium - Google Patents
Verfahren und vorrichtung zur transdermalen verabreichung von lithiumInfo
- Publication number
- ATE373957T1 ATE373957T1 AT98952191T AT98952191T ATE373957T1 AT E373957 T1 ATE373957 T1 AT E373957T1 AT 98952191 T AT98952191 T AT 98952191T AT 98952191 T AT98952191 T AT 98952191T AT E373957 T1 ATE373957 T1 AT E373957T1
- Authority
- AT
- Austria
- Prior art keywords
- lithium
- transdermal administration
- disclosed
- substantially constant
- constant rate
- Prior art date
Links
- WHXSMMKQMYFTQS-UHFFFAOYSA-N Lithium Chemical compound [Li] WHXSMMKQMYFTQS-UHFFFAOYSA-N 0.000 title 1
- 229910052744 lithium Inorganic materials 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/20—Applying electric currents by contact electrodes continuous direct currents
- A61N1/30—Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0009—Galenical forms characterised by the drug release technique; Application systems commanded by energy involving or responsive to electricity, magnetism or acoustic waves; Galenical aspects of sonophoresis, iontophoresis, electroporation or electroosmosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/0404—Electrodes for external use
- A61N1/0408—Use-related aspects
- A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
- A61N1/0432—Anode and cathode
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/325—Applying electric currents by contact electrodes alternating or intermittent currents for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Dermatology (AREA)
- Inorganic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Electrotherapy Devices (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US6214897P | 1997-10-09 | 1997-10-09 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE373957T1 true ATE373957T1 (de) | 2007-10-15 |
Family
ID=22040523
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT98952191T ATE373957T1 (de) | 1997-10-09 | 1998-10-09 | Verfahren und vorrichtung zur transdermalen verabreichung von lithium |
Country Status (7)
Country | Link |
---|---|
US (2) | US6375990B1 (de) |
EP (1) | EP1030560B1 (de) |
AT (1) | ATE373957T1 (de) |
AU (1) | AU9794798A (de) |
CA (1) | CA2308489A1 (de) |
DE (1) | DE69838485T2 (de) |
WO (1) | WO1999018797A1 (de) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU9794798A (en) | 1997-10-09 | 1999-05-03 | Emory University | Method and devices for transdermal delivery of lithium |
US6792306B2 (en) * | 2000-03-10 | 2004-09-14 | Biophoretic Therapeutic Systems, Llc | Finger-mounted electrokinetic delivery system for self-administration of medicaments and methods therefor |
US20030044413A1 (en) * | 2000-08-15 | 2003-03-06 | Regents Of The University Of Minnesota | Methods of limiting apoptosis of cells |
US20020141970A1 (en) * | 2001-03-05 | 2002-10-03 | Pettit Dean K. | Stable aqueous solutions of granulocyte macrophage colony-stimulating factor |
US7378111B2 (en) * | 2002-02-20 | 2008-05-27 | The Trustees Of The University Of Pennsylvania | Regulation of GSK-3α activity for the treatment or prevention of Alzheimer's disease |
GB0507298D0 (en) | 2005-04-11 | 2005-05-18 | Novartis Ag | Organic compounds |
WO2008067409A2 (en) * | 2006-11-28 | 2008-06-05 | Polyplus Battery Company | Protected lithium electrodes for electro-transport drug delivery |
WO2009006349A2 (en) * | 2007-06-29 | 2009-01-08 | Polyplus Battery Company | Electrotransport devices, methods and drug electrode assemblies |
US20090069740A1 (en) * | 2007-09-07 | 2009-03-12 | Polyplus Battery Company | Protected donor electrodes for electro-transport drug delivery |
JP5687901B2 (ja) * | 2007-10-15 | 2015-03-25 | アルザ・コーポレーシヨン | 日に1回の取り替えによるフェンタニルの経皮投与 |
US8280481B2 (en) * | 2007-11-02 | 2012-10-02 | Tyco Healthcare Group Lp | Electrodes possessing pH indicator |
WO2012007387A1 (en) | 2010-07-13 | 2012-01-19 | Medesis Pharma | Low- dose lithium for the treatment of neurodegenerative disorders |
US9114258B2 (en) | 2011-01-04 | 2015-08-25 | Kato Medical Systems Llc | Electrokinetic nerve stimulator |
US20120270860A1 (en) | 2011-04-19 | 2012-10-25 | Gihyun Yoon | Methods for treating or preventing alcohol-related disorders or craving-related disorders |
GB2524777A (en) * | 2014-04-02 | 2015-10-07 | Microarray Ltd | Dressing comprising electrodes |
WO2024232931A1 (en) * | 2023-05-11 | 2024-11-14 | Yon Doo Ough | Apparatus and method for contact free delivery and administration of magnesium as a drug |
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US5252333A (en) | 1987-04-27 | 1993-10-12 | Scotia Holdings Plc | Lithium salt-containing pharmaceutical compositions |
US5162042A (en) | 1988-07-05 | 1992-11-10 | Alza Corporation | Electrotransport transdermal system |
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US5496266A (en) | 1990-04-30 | 1996-03-05 | Alza Corporation | Device and method of iontophoretic drug delivery |
CA2001444C (en) | 1988-10-28 | 2000-07-25 | Darrel F. Untereker | Iontophoresis electrode |
US5057072A (en) | 1988-10-28 | 1991-10-15 | Medtronic, Inc. | Iontophoresis electrode |
US5252334A (en) | 1989-09-08 | 1993-10-12 | Cygnus Therapeutic Systems | Solid matrix system for transdermal drug delivery |
US4950229A (en) | 1989-09-25 | 1990-08-21 | Becton, Dickinson And Company | Apparatus for an electrode used for iontophoresis |
US5320597A (en) | 1991-02-08 | 1994-06-14 | Becton, Dickinson And Company | Device and method for renewing electrodes during iontophoresis |
US5167616A (en) | 1989-12-14 | 1992-12-01 | Alza Corporation | Iontophoretic delivery method |
US5302172A (en) | 1990-03-15 | 1994-04-12 | North Carolina State University | Method and composition for iontophoresis |
AU657681B2 (en) | 1990-03-30 | 1995-03-23 | Alza Corporation | Device and method for iontophoretic drug delivery |
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US5084006A (en) | 1990-03-30 | 1992-01-28 | Alza Corporation | Iontopheretic delivery device |
US5213568A (en) | 1990-03-30 | 1993-05-25 | Medtronic Inc. | Activity controlled electrotransport drug delivery device |
US5162043A (en) | 1990-03-30 | 1992-11-10 | Alza Corporation | Iontophoretic delivery device |
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US5158537A (en) | 1990-10-29 | 1992-10-27 | Alza Corporation | Iontophoretic delivery device and method of hydrating same |
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US5405317A (en) | 1991-05-03 | 1995-04-11 | Alza Corporation | Iontophoretic delivery device |
US5131403A (en) | 1991-06-05 | 1992-07-21 | Becton Dickinson And Company | Method for obtaining blood using iontophoresis |
US5203768A (en) | 1991-07-24 | 1993-04-20 | Alza Corporation | Transdermal delivery device |
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US5411737A (en) | 1991-10-15 | 1995-05-02 | Merck & Co., Inc. | Slow release syneresing polymeric drug delivery device |
CA2121372C (en) | 1991-12-03 | 2003-02-04 | Ronald P. Haak | Iontophoretic delivery device and power supply therefor |
US5256137A (en) | 1992-03-10 | 1993-10-26 | Becton Dickinson And Company | Biphasic power source for use in an iontophoretic drug delivery system |
US5246418A (en) | 1991-12-17 | 1993-09-21 | Becton Dickinson And Company | Iontophresis system having features for reducing skin irritation |
US5260066A (en) * | 1992-01-16 | 1993-11-09 | Srchem Incorporated | Cryogel bandage containing therapeutic agent |
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IL105073A0 (en) | 1992-03-17 | 1993-07-08 | Becton Dickinson Co | User activated iontophoretic device and method for using same |
US5310403A (en) | 1992-05-18 | 1994-05-10 | Becton, Dickinson And Company | Iontophoretic drug delivery device and circuit therefor |
US5310404A (en) | 1992-06-01 | 1994-05-10 | Alza Corporation | Iontophoretic delivery device and method of hydrating same |
DE69407061T2 (de) | 1992-06-02 | 1998-06-04 | Alza Corp., Palo Alto, Calif. | Abgabevorrichtung zur elektrischen übertragung von arzneimitteln |
US5312326A (en) | 1992-06-02 | 1994-05-17 | Alza Corporation | Iontophoretic drug delivery apparatus |
US5264219A (en) | 1992-08-07 | 1993-11-23 | Minnesota Mining And Manufacturing Company | Transdermal drug delivery backing |
US5306235A (en) | 1992-09-30 | 1994-04-26 | Becton Dickinson And Company | Failsafe iontophoresis drug delivery system |
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US5427585A (en) | 1993-03-29 | 1995-06-27 | Bettinger; David S. | On-demand iontophoretic system |
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US5458569A (en) | 1993-06-08 | 1995-10-17 | Becton Dickinson And Company | Wearable iontophoresis system |
US5645854A (en) | 1993-06-23 | 1997-07-08 | Masiz; John J. | Molecular transdermal transport system |
US5460821A (en) | 1993-06-23 | 1995-10-24 | Masiz; John J. | Molecular transdermal transport system |
USD352113S (en) | 1993-08-05 | 1994-11-01 | Becton Dickinson And Company | Iontophoretic drug delivery system |
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US5744155A (en) | 1993-08-13 | 1998-04-28 | Friedman; Doron | Bioadhesive emulsion preparations for enhanced drug delivery |
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US5540669A (en) | 1993-09-30 | 1996-07-30 | Becton, Dickinson And Company | Iontophoretic drug delivery system and method for using same |
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US5645526A (en) | 1994-09-30 | 1997-07-08 | Becton Dickinson And Company | Apparatus and method for ensuring compatibility of a reusable iontophoretic controller with an iontophoretic patch |
US5688231A (en) | 1994-09-30 | 1997-11-18 | Becton Dickinson And Company | Iontophoresis assembly including cleanable electrical contacts |
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JPH10509694A (ja) | 1994-09-30 | 1998-09-22 | ベクトン・ディッキンソン・アンド・カンパニー | 安定性及び在庫期間を増すためにイオン浸透療法による薬剤投与パッチ等を形成し且つ包装するための方法 |
US5498235A (en) | 1994-09-30 | 1996-03-12 | Becton Dickinson And Company | Iontophoresis assembly including patch/controller attachment |
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US5736580A (en) | 1994-11-14 | 1998-04-07 | Alza Croporation | Composition, device, and method for electrotransport agent delivery |
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US5688232A (en) | 1995-09-28 | 1997-11-18 | Becton Dickinson And Company | Iontophoretic drug delivery device having an improved controller |
AU7254496A (en) | 1995-09-29 | 1997-04-17 | Becton Dickinson & Company | Low-cost electrodes for an iontophoretic device |
WO1997012644A1 (en) | 1995-09-29 | 1997-04-10 | Becton Dickinson And Company | Improved iontophoretic reservoir apparatus |
US6060638A (en) | 1995-12-22 | 2000-05-09 | Kimberly-Clark Worldwide, Inc. | Matched permeability liner/absorbent structure system for absorbent articles and the like |
IT1284849B1 (it) * | 1996-06-10 | 1998-05-22 | Ist Farmacoterapico It Spa | Cerotto a rilascio controllato di litio. |
US5693024A (en) | 1996-09-27 | 1997-12-02 | Becton Dickinson And Company | Iontophoretic drug delivery system, including method for determining hydration of patch |
AU9794798A (en) * | 1997-10-09 | 1999-05-03 | Emory University | Method and devices for transdermal delivery of lithium |
-
1998
- 1998-10-09 AU AU97947/98A patent/AU9794798A/en not_active Abandoned
- 1998-10-09 US US09/529,248 patent/US6375990B1/en not_active Expired - Lifetime
- 1998-10-09 CA CA002308489A patent/CA2308489A1/en not_active Abandoned
- 1998-10-09 DE DE69838485T patent/DE69838485T2/de not_active Expired - Lifetime
- 1998-10-09 WO PCT/US1998/021320 patent/WO1999018797A1/en active IP Right Grant
- 1998-10-09 EP EP98952191A patent/EP1030560B1/de not_active Expired - Lifetime
- 1998-10-09 AT AT98952191T patent/ATE373957T1/de not_active IP Right Cessation
-
2002
- 2002-04-22 US US10/127,257 patent/US20020160056A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
AU9794798A (en) | 1999-05-03 |
WO1999018797A1 (en) | 1999-04-22 |
US6375990B1 (en) | 2002-04-23 |
CA2308489A1 (en) | 1999-04-22 |
DE69838485D1 (de) | 2007-11-08 |
US20020160056A1 (en) | 2002-10-31 |
EP1030560A1 (de) | 2000-08-30 |
EP1030560B1 (de) | 2007-09-26 |
DE69838485T2 (de) | 2008-06-26 |
EP1030560A4 (de) | 2004-11-17 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |