KR900700080A - 제법에 있어서 불용상들을 포함하는 다공성 입자 - Google Patents
제법에 있어서 불용상들을 포함하는 다공성 입자Info
- Publication number
- KR900700080A KR900700080A KR1019890702419A KR890702419A KR900700080A KR 900700080 A KR900700080 A KR 900700080A KR 1019890702419 A KR1019890702419 A KR 1019890702419A KR 890702419 A KR890702419 A KR 890702419A KR 900700080 A KR900700080 A KR 900700080A
- Authority
- KR
- South Korea
- Prior art keywords
- phase
- composition
- liquid
- microns
- solid particles
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J9/00—Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof
- C08J9/28—Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof by elimination of a liquid phase from a macromolecular composition or article, e.g. drying of coagulum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/0241—Containing particulates characterized by their shape and/or structure
- A61K8/0283—Matrix particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/60—Particulates further characterized by their structure or composition
- A61K2800/65—Characterized by the composition of the particulate/core
- A61K2800/654—The particulate/core comprising macromolecular material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q1/00—Make-up preparations; Body powders; Preparations for removing make-up
- A61Q1/02—Preparations containing skin colorants, e.g. pigments
- A61Q1/04—Preparations containing skin colorants, e.g. pigments for lips
- A61Q1/06—Lipsticks
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dispersion Chemistry (AREA)
- Birds (AREA)
- Mathematical Physics (AREA)
- Physics & Mathematics (AREA)
- Dermatology (AREA)
- Materials Engineering (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Cosmetics (AREA)
- Manufacturing Of Micro-Capsules (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Description
Claims (17)
- 제1상과 거의 불용인 제2상에서 제1상의 안정한 현탁액을 형성하는 방법에 있어서, (a) 외부에 개방된 기공이 거의 연속적인 네트워크를 형성하는 고체입자에 모세관 현상으로 상기 기공에 유지되는 제1상을 제공하고; (b) 상기 입자를 상기 제2상에 분산시키는 것을 포함하는 방법.
- 제1항에 있어서, 상기 고체입자가 약 1 내지 100미크론의 평균직경을 가지는 방법.
- 제1항에 있어서, 상기 고체입자가 약 0.01cc/g 내지 약 4.0cc/g의 총기공체적, 약 1㎡/g 내지 약 500㎡/g의 표면적 및 약 0.001 미크론 내지 약 3.0 미크론의 평균 기공 직경을 가지는 방법.
- 제1항에 있어서, 상기 고체 입자가 스티렌과 디비닐벤젠의 공중합체 또는 메틸메타크릴레이트와 에틸렌 글리콜 디메타크릴레이트인 가교된 중합체로 형성되는 방법.
- 제1항에 있어서, 상기 고체입자와 상기 제1상이 상기 현탁액의 약 1체적% 내지 약 50체적%를 포함하는 방법.
- 제1항에 있어서, 상기 제1상이 거의 비극성의 소수성 물질이고 상기 제2상은 거의 극성의 친수성 액체인 방법.
- 제1항에 있어서, 상기 제1액체상이 거의 극성의 친수성 액체 연석제이고, 상기 제2상은 거의 비극성의 소수성 물질인 방법.
- 제1항에 있어서, 상기 제1액체상이 거의 극성의 친수성 용매이고 상기 제2상은 거의 비극성의 소수성물질인 방법.
- 제1항에 있어서, 상기 제1액체상은 프로필렌 글리콜과 프로필렌 카르보네이트로 구성되는 그룹으로부터 선택된 극성 용매에 함유된 코르티코스테로이드 용액이고, 상기 제2상이 와셀린(petrolatum)인 방법.
- 연속상에 분산되고, 제각기 외부에 개방된 기공이 거의 연속적인 네트워크를 형성하고, 상기 기공에 유지된 상기 연속상과 거의 불용인 물질을 가진 교체입자를 포함하는 조성물.
- 제10항에 있어서, 상기 고체입자가 약 1미크론 내지 약 100미크론의 평균직경을 가지는 조성물.
- 제10항에 있어서, 상기 교체입자가 약 0.01cc/g 내지 약 4.0cc/g의 총기공 체적, 약 1㎡/g 내지 약 500㎡/g의 표면적 및 약 0.001 미크론 내지 약 3.0 미크론의 평균기공 직경을 가지는 조성물.
- 제10항에 있어서, 상기 교체입자가 스티렌과 디비닐벤젠의 공중합체 또는 메틸메타크릴레이트와 에틸글리콜 디메타크릴레이트인 가교된 중합체로 형성되는 조성물.
- 제10항에 있어서, 상기 고체입자와 상기 액체가 상기 현택액의 약 1체적% 내지 약 50체적%를 포함하는 조성물.
- 제10항에 있어서, 상기 물질이 거의 비극성의 소수성 액체이고 상기 연속상은 거의 극성의 친수성 액체인 조성물.
- 제10항에 있어서, 상기 물질이 거의 극성의 친수성 액체 연석제이고 상기 연속상은 거의 비극성의 소수성 액체인 조성물.
- 제10항에 있어서, 상기 물질이 프로필렌 글리콜과 프로필렌 카르보네이트로 구성되는 그룹으로부터 선택된 극성 용매에 함유된 코르티코스테로이드 용액이고, 상기 제2상이 와셀린(petrolatum)인 조성물.※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US18520488A | 1988-04-22 | 1988-04-22 | |
US185,204 | 1988-04-22 | ||
PCT/US1989/001678 WO1989010132A1 (en) | 1988-04-22 | 1989-04-20 | Porous particles in preparations involving immiscible phases |
Publications (2)
Publication Number | Publication Date |
---|---|
KR900700080A true KR900700080A (ko) | 1990-08-11 |
KR960009406B1 KR960009406B1 (en) | 1996-07-19 |
Family
ID=22680033
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR89702419A KR960009406B1 (en) | 1988-04-22 | 1989-12-21 | Porous particles in preparations involving immiscible phases |
Country Status (7)
Country | Link |
---|---|
US (1) | US5135740A (ko) |
EP (1) | EP0374217A4 (ko) |
JP (1) | JPH03500507A (ko) |
KR (1) | KR960009406B1 (ko) |
AU (1) | AU612839B2 (ko) |
WO (1) | WO1989010132A1 (ko) |
ZA (1) | ZA892859B (ko) |
Families Citing this family (48)
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US5035890A (en) * | 1989-04-10 | 1991-07-30 | Dow Corning Corporation | Emulsifier-free hand and body lotion |
US5320835A (en) * | 1989-10-25 | 1994-06-14 | Avon Products, Inc. | Cosmetic formulation having a palette of color shades renewable by mechanical action |
US5422117A (en) * | 1990-06-28 | 1995-06-06 | Edko Trading And Representation Company Ltd. | Multiphase pharmaceutical formulations |
US5281413A (en) * | 1990-10-05 | 1994-01-25 | Dow Corning Corporation | Antiperspirant stick containing a macroporous polymer |
US5387411A (en) * | 1990-10-05 | 1995-02-07 | Dow Corning Corporation | Antiperspirant containing a hydrophobic macroporous polymer as the suspending agent |
US5135660A (en) * | 1991-01-07 | 1992-08-04 | Dow Corning Corporation | Method of recovering oil from the surface of water |
US5145685A (en) * | 1991-04-08 | 1992-09-08 | Dow Corning Corporation | Skin treatment method and composition |
FR2675377B1 (fr) * | 1991-04-22 | 1995-02-03 | Oreal | Microspheres poreuses enrobees a l'aide d'une huile perfluoree, d'une huile de silicone fluoree ou d'une gomme de silicone et leur utilisation en cosmetique. |
US5683707A (en) * | 1992-11-12 | 1997-11-04 | Johnson; Richard R. | Biostatic media for active agents |
US5603927A (en) * | 1992-12-08 | 1997-02-18 | Kabushiki Kaisha Toyota Chuo Kenkyusho | Material for removing offensive odor |
US5583162A (en) * | 1994-06-06 | 1996-12-10 | Biopore Corporation | Polymeric microbeads and method of preparation |
US5534265A (en) * | 1994-08-26 | 1996-07-09 | The Procter & Gamble Company | Thickened nonabrasive personal cleansing compositions |
EP0777464A1 (en) * | 1994-08-26 | 1997-06-11 | The Procter & Gamble Company | Personal cleansing compositions |
US6107429A (en) * | 1994-10-24 | 2000-08-22 | Amcol International Corporation | Process for producing an oil and water adsorbent polymer capable of entrapping solid particles and liquids and the product thereof |
US5837790A (en) | 1994-10-24 | 1998-11-17 | Amcol International Corporation | Precipitation polymerization process for producing an oil adsorbent polymer capable of entrapping solid particles and liquids and the product thereof |
US5830967A (en) * | 1994-10-24 | 1998-11-03 | Amcol International Corporation | Process for producing an oil and water adsorbent polymer capable of entrapping solid particles and liquids and the product thereof |
US6214300B1 (en) | 1994-12-02 | 2001-04-10 | The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration | Microencapsulation and electrostatic processing device |
EP0749746B1 (fr) * | 1995-06-21 | 1997-09-03 | L'oreal | Composition cosmétique comprenant une dispersion de particule de polymère |
FR2742355B1 (fr) * | 1995-12-14 | 1998-02-06 | Aimco Sa | Procede pour disperser de facon homogene au moins un reactif dans une matrice fluide et produits obtenus |
US5851538A (en) * | 1995-12-29 | 1998-12-22 | Advanced Polymer Systems, Inc. | Retinoid formulations in porous microspheres for reduced irritation and enhanced stability |
US5925607A (en) * | 1996-04-01 | 1999-07-20 | Sara Lee Corporation | Cleaning and polishing composition |
US5753607A (en) * | 1996-04-01 | 1998-05-19 | Sara Lee Corporation | Cleaning and polishing composition |
US5904918A (en) * | 1996-11-04 | 1999-05-18 | L'oreal S.A. | Cosmetic powder composition |
US6048908A (en) * | 1997-06-27 | 2000-04-11 | Biopore Corporation | Hydrophilic polymeric material |
JPH11130617A (ja) * | 1997-10-28 | 1999-05-18 | Pola Chem Ind Inc | のびのある皮膚外用剤 |
US6228894B1 (en) | 1998-04-17 | 2001-05-08 | Enhanced Derm Technologies, Inc. | Softgel-compatible composition containing retinol |
US5891470A (en) * | 1998-04-17 | 1999-04-06 | Advanced Polymer Systems, Inc. | Softgel formulation containing retinol |
US6670335B2 (en) | 2001-03-05 | 2003-12-30 | A. P. Pharma, Inc. | Fluorouracil-containing formulation |
US20030152630A1 (en) * | 2001-05-11 | 2003-08-14 | Ng Steven Y. | PEG-POE, PEG-POE-PEG, and POE-PEG-POE block copolymers |
US6590059B2 (en) * | 2001-05-11 | 2003-07-08 | Ap Pharma, Inc. | Bioerodible polyorthoesters from dioxolane-based diketene acetals |
US6524606B1 (en) | 2001-11-16 | 2003-02-25 | Ap Pharma, Inc. | Bioerodible polyorthoesters containing amine groups |
US20040105906A1 (en) * | 2002-03-22 | 2004-06-03 | Arbiser Jack L. | Antiagionecic, antitumor, chemopreventative agents |
US7098252B2 (en) * | 2002-04-01 | 2006-08-29 | Rohm And Haas Company | Preparation of macroreticular polymers |
SE0201623D0 (sv) * | 2002-05-30 | 2002-05-30 | Amersham Biosciences Ab | Macroporous cross-linked polymer particles |
AU2003301672A1 (en) * | 2002-10-21 | 2004-05-13 | Allegiance Corporation | Coating composition for skin-contacting surface of elastomeric articles and articles containing the same |
US20050107581A1 (en) * | 2003-11-17 | 2005-05-19 | Bruce Rosenbaum | Process for the removal of porogens from temperature sensitive macroreticular polymers using steam at reduced pressure |
WO2006065991A2 (en) * | 2004-12-17 | 2006-06-22 | Dr. Reddy's Laboratories Ltd. | Dispersion for delivering active agents |
US8053000B2 (en) | 2005-06-07 | 2011-11-08 | Dr. Reddy's Laboratories Limited | Compositions for drug delivery |
US20080020023A1 (en) | 2006-07-20 | 2008-01-24 | Shiping Wang | Nonaqueous coating composition for elastomeric articles and articles containing the same |
US20100183688A1 (en) * | 2006-07-24 | 2010-07-22 | Amcol International Corporation | Delivery System and Method of Manufacturing the Same |
WO2010089763A2 (en) | 2008-06-30 | 2010-08-12 | Reliance Life Sciences Pvt. Ltd. | Poly(n-vinyl caprolactam-co-acrylamide) microparticles for controlled release applications |
SG10201704847WA (en) * | 2009-10-01 | 2017-07-28 | Adare Pharmaceuticals Inc | Orally administered corticosteroid compositions |
EP2603318B1 (en) | 2010-08-13 | 2020-05-13 | Shell Oil Company | A chelant and polar additive containing composition for hydroprocessing of hydrocarbon feedstocks |
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JP6101346B2 (ja) | 2012-06-08 | 2017-03-22 | バイオトロニック アクチェンゲゼルシャフト | ラパマイシン−40−o−環状炭化水素エステル、組成物及び方法 |
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-
1989
- 1989-04-19 ZA ZA892859A patent/ZA892859B/xx unknown
- 1989-04-20 JP JP1505253A patent/JPH03500507A/ja active Pending
- 1989-04-20 EP EP19890905520 patent/EP0374217A4/en not_active Withdrawn
- 1989-04-20 AU AU35568/89A patent/AU612839B2/en not_active Ceased
- 1989-04-20 WO PCT/US1989/001678 patent/WO1989010132A1/en not_active Application Discontinuation
- 1989-10-02 US US07/418,776 patent/US5135740A/en not_active Expired - Lifetime
- 1989-12-21 KR KR89702419A patent/KR960009406B1/ko active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
KR960009406B1 (en) | 1996-07-19 |
EP0374217A1 (en) | 1990-06-27 |
EP0374217A4 (en) | 1990-12-05 |
US5135740A (en) | 1992-08-04 |
WO1989010132A1 (en) | 1989-11-02 |
ZA892859B (en) | 1989-12-27 |
JPH03500507A (ja) | 1991-02-07 |
AU3556889A (en) | 1989-11-24 |
AU612839B2 (en) | 1991-07-18 |
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