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KR900700080A - 제법에 있어서 불용상들을 포함하는 다공성 입자 - Google Patents

제법에 있어서 불용상들을 포함하는 다공성 입자

Info

Publication number
KR900700080A
KR900700080A KR1019890702419A KR890702419A KR900700080A KR 900700080 A KR900700080 A KR 900700080A KR 1019890702419 A KR1019890702419 A KR 1019890702419A KR 890702419 A KR890702419 A KR 890702419A KR 900700080 A KR900700080 A KR 900700080A
Authority
KR
South Korea
Prior art keywords
phase
composition
liquid
microns
solid particles
Prior art date
Application number
KR1019890702419A
Other languages
English (en)
Other versions
KR960009406B1 (en
Inventor
마틴 카츠
충 헹 청
Original Assignee
원본미기재
어드배스드 폴리머 시스템 인코오포레이티드
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 원본미기재, 어드배스드 폴리머 시스템 인코오포레이티드 filed Critical 원본미기재
Publication of KR900700080A publication Critical patent/KR900700080A/ko
Application granted granted Critical
Publication of KR960009406B1 publication Critical patent/KR960009406B1/ko

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Classifications

    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08JWORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J9/00Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof
    • C08J9/28Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof by elimination of a liquid phase from a macromolecular composition or article, e.g. drying of coagulum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/02Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0241Containing particulates characterized by their shape and/or structure
    • A61K8/0283Matrix particles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1635Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/60Particulates further characterized by their structure or composition
    • A61K2800/65Characterized by the composition of the particulate/core
    • A61K2800/654The particulate/core comprising macromolecular material
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q1/00Make-up preparations; Body powders; Preparations for removing make-up
    • A61Q1/02Preparations containing skin colorants, e.g. pigments
    • A61Q1/04Preparations containing skin colorants, e.g. pigments for lips
    • A61Q1/06Lipsticks

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dispersion Chemistry (AREA)
  • Birds (AREA)
  • Mathematical Physics (AREA)
  • Physics & Mathematics (AREA)
  • Dermatology (AREA)
  • Materials Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

내용 없음

Description

제법에 있어서 불용상들을 포함하는 다공성 입자
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (17)

  1. 제1상과 거의 불용인 제2상에서 제1상의 안정한 현탁액을 형성하는 방법에 있어서, (a) 외부에 개방된 기공이 거의 연속적인 네트워크를 형성하는 고체입자에 모세관 현상으로 상기 기공에 유지되는 제1상을 제공하고; (b) 상기 입자를 상기 제2상에 분산시키는 것을 포함하는 방법.
  2. 제1항에 있어서, 상기 고체입자가 약 1 내지 100미크론의 평균직경을 가지는 방법.
  3. 제1항에 있어서, 상기 고체입자가 약 0.01cc/g 내지 약 4.0cc/g의 총기공체적, 약 1㎡/g 내지 약 500㎡/g의 표면적 및 약 0.001 미크론 내지 약 3.0 미크론의 평균 기공 직경을 가지는 방법.
  4. 제1항에 있어서, 상기 고체 입자가 스티렌과 디비닐벤젠의 공중합체 또는 메틸메타크릴레이트와 에틸렌 글리콜 디메타크릴레이트인 가교된 중합체로 형성되는 방법.
  5. 제1항에 있어서, 상기 고체입자와 상기 제1상이 상기 현탁액의 약 1체적% 내지 약 50체적%를 포함하는 방법.
  6. 제1항에 있어서, 상기 제1상이 거의 비극성의 소수성 물질이고 상기 제2상은 거의 극성의 친수성 액체인 방법.
  7. 제1항에 있어서, 상기 제1액체상이 거의 극성의 친수성 액체 연석제이고, 상기 제2상은 거의 비극성의 소수성 물질인 방법.
  8. 제1항에 있어서, 상기 제1액체상이 거의 극성의 친수성 용매이고 상기 제2상은 거의 비극성의 소수성물질인 방법.
  9. 제1항에 있어서, 상기 제1액체상은 프로필렌 글리콜과 프로필렌 카르보네이트로 구성되는 그룹으로부터 선택된 극성 용매에 함유된 코르티코스테로이드 용액이고, 상기 제2상이 와셀린(petrolatum)인 방법.
  10. 연속상에 분산되고, 제각기 외부에 개방된 기공이 거의 연속적인 네트워크를 형성하고, 상기 기공에 유지된 상기 연속상과 거의 불용인 물질을 가진 교체입자를 포함하는 조성물.
  11. 제10항에 있어서, 상기 고체입자가 약 1미크론 내지 약 100미크론의 평균직경을 가지는 조성물.
  12. 제10항에 있어서, 상기 교체입자가 약 0.01cc/g 내지 약 4.0cc/g의 총기공 체적, 약 1㎡/g 내지 약 500㎡/g의 표면적 및 약 0.001 미크론 내지 약 3.0 미크론의 평균기공 직경을 가지는 조성물.
  13. 제10항에 있어서, 상기 교체입자가 스티렌과 디비닐벤젠의 공중합체 또는 메틸메타크릴레이트와 에틸글리콜 디메타크릴레이트인 가교된 중합체로 형성되는 조성물.
  14. 제10항에 있어서, 상기 고체입자와 상기 액체가 상기 현택액의 약 1체적% 내지 약 50체적%를 포함하는 조성물.
  15. 제10항에 있어서, 상기 물질이 거의 비극성의 소수성 액체이고 상기 연속상은 거의 극성의 친수성 액체인 조성물.
  16. 제10항에 있어서, 상기 물질이 거의 극성의 친수성 액체 연석제이고 상기 연속상은 거의 비극성의 소수성 액체인 조성물.
  17. 제10항에 있어서, 상기 물질이 프로필렌 글리콜과 프로필렌 카르보네이트로 구성되는 그룹으로부터 선택된 극성 용매에 함유된 코르티코스테로이드 용액이고, 상기 제2상이 와셀린(petrolatum)인 조성물.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR89702419A 1988-04-22 1989-12-21 Porous particles in preparations involving immiscible phases KR960009406B1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US18520488A 1988-04-22 1988-04-22
US185,204 1988-04-22
PCT/US1989/001678 WO1989010132A1 (en) 1988-04-22 1989-04-20 Porous particles in preparations involving immiscible phases

Publications (2)

Publication Number Publication Date
KR900700080A true KR900700080A (ko) 1990-08-11
KR960009406B1 KR960009406B1 (en) 1996-07-19

Family

ID=22680033

Family Applications (1)

Application Number Title Priority Date Filing Date
KR89702419A KR960009406B1 (en) 1988-04-22 1989-12-21 Porous particles in preparations involving immiscible phases

Country Status (7)

Country Link
US (1) US5135740A (ko)
EP (1) EP0374217A4 (ko)
JP (1) JPH03500507A (ko)
KR (1) KR960009406B1 (ko)
AU (1) AU612839B2 (ko)
WO (1) WO1989010132A1 (ko)
ZA (1) ZA892859B (ko)

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Also Published As

Publication number Publication date
KR960009406B1 (en) 1996-07-19
EP0374217A1 (en) 1990-06-27
EP0374217A4 (en) 1990-12-05
US5135740A (en) 1992-08-04
WO1989010132A1 (en) 1989-11-02
ZA892859B (en) 1989-12-27
JPH03500507A (ja) 1991-02-07
AU3556889A (en) 1989-11-24
AU612839B2 (en) 1991-07-18

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