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JPS57142911A - Absorption-improving agent - Google Patents

Absorption-improving agent

Info

Publication number
JPS57142911A
JPS57142911A JP2766381A JP2766381A JPS57142911A JP S57142911 A JPS57142911 A JP S57142911A JP 2766381 A JP2766381 A JP 2766381A JP 2766381 A JP2766381 A JP 2766381A JP S57142911 A JPS57142911 A JP S57142911A
Authority
JP
Japan
Prior art keywords
oil
ubiquinone
absorption
starch
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2766381A
Other languages
Japanese (ja)
Inventor
Shimesu Motoyama
Satoru Sato
Seiichi Umeda
Hirotsune Yasumi
Emiko Sudo
Takuichi Tsujino
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
FUROINTO SANGYO KK
Freund Corp
Original Assignee
FUROINTO SANGYO KK
Freund Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by FUROINTO SANGYO KK, Freund Corp filed Critical FUROINTO SANGYO KK
Priority to JP2766381A priority Critical patent/JPS57142911A/en
Publication of JPS57142911A publication Critical patent/JPS57142911A/en
Pending legal-status Critical Current

Links

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  • Medicinal Preparation (AREA)

Abstract

PURPOSE: To provide a ubiquinone preparation having improved peroral absorption of hardly water-soluble ubiquinone through the digestive tracts to the lymph, by dispersing ubiquinone in an oil, and adsorbing the dispersion to powder.
CONSTITUTION: Ubiquinone is dispersed in a water-insoluble or hardly soluble oil which is preferably liquid at normal temperature and is composed of an oil or fat, lipoid, wax, essential oil and/or mineral oil. The titled agent can be prepared by adsorbing the dispersion to non-toxic powder having preferably high adsorption capacity, e.g. granulated β-starch obtained by granulating β-starch with a fluidized bed granulator, etc. using α-starch liquid as a binder. Said preparation gives large AUC (area under the curve of blood concentration), exhibits high bioavailability, and is advantageous because the active component is transferred to the lymph and is not metabolized in the liver. Addition of digestive enzyme to the preparation further improves the absorption-improving effect.
COPYRIGHT: (C)1982,JPO&Japio
JP2766381A 1981-02-28 1981-02-28 Absorption-improving agent Pending JPS57142911A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2766381A JPS57142911A (en) 1981-02-28 1981-02-28 Absorption-improving agent

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2766381A JPS57142911A (en) 1981-02-28 1981-02-28 Absorption-improving agent

Publications (1)

Publication Number Publication Date
JPS57142911A true JPS57142911A (en) 1982-09-03

Family

ID=12227170

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2766381A Pending JPS57142911A (en) 1981-02-28 1981-02-28 Absorption-improving agent

Country Status (1)

Country Link
JP (1) JPS57142911A (en)

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4684520A (en) * 1984-04-09 1987-08-04 Seuref A.G. Pharmaceutical compositions having cerebral antianoxic and metabolic activities
JPH08268914A (en) * 1994-10-17 1996-10-15 Akzo Nobel Nv Solid pharmaceutical composition comprising an excipient capable of binding water
WO2003061395A1 (en) * 2002-01-18 2003-07-31 Kaneka Corporation Ubiquinol-enriched fat-containing foods
WO2003061396A1 (en) * 2002-01-18 2003-07-31 Kaneka Corporation Ubiquinone-enriched foods
JP2007501218A (en) * 2003-08-04 2007-01-25 ファイザー・プロダクツ・インク Pharmaceutical composition of adsorbate of amorphous drug and lipophilic microphase-forming substance
US8158162B2 (en) 2001-11-14 2012-04-17 Jarrow Formulas, Inc. Eutectic-based self-nanoemulsified drug delivery system
US8506995B2 (en) 1999-03-29 2013-08-13 Soft Gel Technologies, Inc. Coenzyme Q10 formulation and process methodology for soft gel capsules manufacturing
US10166192B2 (en) 2003-09-29 2019-01-01 Soft Gel Technologies, Inc. Solubilized CoQ-10
US10314793B2 (en) 2003-09-29 2019-06-11 Soft Gel Technologies, Inc. Solubilized CoQ-10

Cited By (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4684520A (en) * 1984-04-09 1987-08-04 Seuref A.G. Pharmaceutical compositions having cerebral antianoxic and metabolic activities
JPH08268914A (en) * 1994-10-17 1996-10-15 Akzo Nobel Nv Solid pharmaceutical composition comprising an excipient capable of binding water
US8506995B2 (en) 1999-03-29 2013-08-13 Soft Gel Technologies, Inc. Coenzyme Q10 formulation and process methodology for soft gel capsules manufacturing
US8158162B2 (en) 2001-11-14 2012-04-17 Jarrow Formulas, Inc. Eutectic-based self-nanoemulsified drug delivery system
US8790723B2 (en) 2001-11-14 2014-07-29 Jarrow Formulas, Inc. Eutectic-based self-nanoemulsified drug delivery system
JPWO2003061395A1 (en) * 2002-01-18 2005-05-19 株式会社カネカ Oil-containing food enriched with ubiquinol
CN100448359C (en) * 2002-01-18 2009-01-07 钟渊化学工业株式会社 Ubiquinone-enriched foods
JP2009278994A (en) * 2002-01-18 2009-12-03 Kaneka Corp Ubiquinol-enriched fat-containing foods
US7678404B2 (en) 2002-01-18 2010-03-16 Kaneka Corporation Ubiquinone-enriched foods
US7897169B2 (en) 2002-01-18 2011-03-01 Kaneka Corporation Ubiquinol-enriched fat-containing foods
WO2003061396A1 (en) * 2002-01-18 2003-07-31 Kaneka Corporation Ubiquinone-enriched foods
WO2003061395A1 (en) * 2002-01-18 2003-07-31 Kaneka Corporation Ubiquinol-enriched fat-containing foods
JP2007501218A (en) * 2003-08-04 2007-01-25 ファイザー・プロダクツ・インク Pharmaceutical composition of adsorbate of amorphous drug and lipophilic microphase-forming substance
US10166192B2 (en) 2003-09-29 2019-01-01 Soft Gel Technologies, Inc. Solubilized CoQ-10
US10166193B2 (en) 2003-09-29 2019-01-01 Soft Gel Technologies, Inc. Method of making a soft gel capsule comprising CoQ-10 solubilized in a monoterpene
US10314793B2 (en) 2003-09-29 2019-06-11 Soft Gel Technologies, Inc. Solubilized CoQ-10

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