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JPS6471822A - Ophthalmic sustained release preparation - Google Patents

Ophthalmic sustained release preparation

Info

Publication number
JPS6471822A
JPS6471822A JP22925087A JP22925087A JPS6471822A JP S6471822 A JPS6471822 A JP S6471822A JP 22925087 A JP22925087 A JP 22925087A JP 22925087 A JP22925087 A JP 22925087A JP S6471822 A JPS6471822 A JP S6471822A
Authority
JP
Japan
Prior art keywords
high polymer
soluble
water
preparation
base
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP22925087A
Other languages
Japanese (ja)
Inventor
Seiji Azuma
Yoko Mitani
Kazuya Taniguchi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rohto Pharmaceutical Co Ltd
Original Assignee
Rohto Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rohto Pharmaceutical Co Ltd filed Critical Rohto Pharmaceutical Co Ltd
Priority to JP22925087A priority Critical patent/JPS6471822A/en
Publication of JPS6471822A publication Critical patent/JPS6471822A/en
Pending legal-status Critical Current

Links

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  • Medicinal Preparation (AREA)

Abstract

PURPOSE:To obtain the titled preparation having excellent local affinity, controlling action on release of drug, capable of maintaining medicinal effects for a long time, by dispersing particles of a high polymer of specific properties into a water-soluble high polymer. CONSTITUTION:One or more of ophthalmic remedying active substances (e.g. beta-adrenergic blocker such as timolol or befunolol) are dispersed into a base for preparation. The base is obtained by dispersing granules comprising a water- insoluble high polymer (e.g. methyl cellulose), a high polymer (e.g. polyglycolic acid) decomposable in organisms or a high polymer soluble in a limited pH range (soluble at pH 4-6) into a water-soluble high polymer. In pharmaceutical preparation, the dispersion is molded into a filmy, sheet-like or disclike solid substance or a gelatinous or ointment semisolid.
JP22925087A 1987-09-12 1987-09-12 Ophthalmic sustained release preparation Pending JPS6471822A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP22925087A JPS6471822A (en) 1987-09-12 1987-09-12 Ophthalmic sustained release preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP22925087A JPS6471822A (en) 1987-09-12 1987-09-12 Ophthalmic sustained release preparation

Publications (1)

Publication Number Publication Date
JPS6471822A true JPS6471822A (en) 1989-03-16

Family

ID=16889167

Family Applications (1)

Application Number Title Priority Date Filing Date
JP22925087A Pending JPS6471822A (en) 1987-09-12 1987-09-12 Ophthalmic sustained release preparation

Country Status (1)

Country Link
JP (1) JPS6471822A (en)

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2688694A1 (en) * 1992-03-20 1993-09-24 Vetoquinol Sa BIOADHESIVE OPHTHALMIC INSERT.
WO1994005257A1 (en) * 1992-09-08 1994-03-17 Allergan, Inc. Sustained release of ophthalmic drugs from a soluble polymer drug delivery vehicle
US5296228A (en) * 1992-03-13 1994-03-22 Allergan, Inc. Compositions for controlled delivery of pharmaceutical compounds
JPH09509166A (en) * 1994-02-18 1997-09-16 チバ−ガイギー アクチエンゲゼルシャフト Sustained release delivery system for ophthalmic liquids
JP2007056014A (en) * 2005-07-29 2007-03-08 Santen Pharmaceut Co Ltd Noninvasive drug delivery system to posterior part tissue of eye by using gel-like composition
JP2007056015A (en) * 2005-07-29 2007-03-08 Santen Pharmaceut Co Ltd Noninvasive drug delivery system to posterior part tissue of eye by using solid composition
JP2008502727A (en) * 2004-06-10 2008-01-31 グラット エアー テクニクス インコーポレーテッド Sustained release base pharmaceutical preparation
JP2008533204A (en) * 2005-03-21 2008-08-21 マクサイト， インコーポレイテッド Drug delivery system for treatment of disease or condition
JP2009524652A (en) * 2006-01-27 2009-07-02 シージェイ チェイルジェダン コーポレイション Zaltoprofen-containing sustained release tablet and method for producing the same
JP2011037892A (en) * 2002-09-30 2011-02-24 Mark A Babizhayev Treatment means
JP2013129604A (en) * 2011-12-20 2013-07-04 Kowa Co Sustained release film preparation containing glaucoma treating agent

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5296228A (en) * 1992-03-13 1994-03-22 Allergan, Inc. Compositions for controlled delivery of pharmaceutical compounds
FR2688694A1 (en) * 1992-03-20 1993-09-24 Vetoquinol Sa BIOADHESIVE OPHTHALMIC INSERT.
WO1994005257A1 (en) * 1992-09-08 1994-03-17 Allergan, Inc. Sustained release of ophthalmic drugs from a soluble polymer drug delivery vehicle
JPH09509166A (en) * 1994-02-18 1997-09-16 チバ−ガイギー アクチエンゲゼルシャフト Sustained release delivery system for ophthalmic liquids
JP2011037892A (en) * 2002-09-30 2011-02-24 Mark A Babizhayev Treatment means
JP2008502727A (en) * 2004-06-10 2008-01-31 グラット エアー テクニクス インコーポレーテッド Sustained release base pharmaceutical preparation
JP2013216711A (en) * 2004-06-10 2013-10-24 Glatt Air Techniques Inc Controlled release matrix pharmaceutical dosage formulation
JP2008533204A (en) * 2005-03-21 2008-08-21 マクサイト， インコーポレイテッド Drug delivery system for treatment of disease or condition
JP2007056014A (en) * 2005-07-29 2007-03-08 Santen Pharmaceut Co Ltd Noninvasive drug delivery system to posterior part tissue of eye by using gel-like composition
JP2007056015A (en) * 2005-07-29 2007-03-08 Santen Pharmaceut Co Ltd Noninvasive drug delivery system to posterior part tissue of eye by using solid composition
JP2009524652A (en) * 2006-01-27 2009-07-02 シージェイ チェイルジェダン コーポレイション Zaltoprofen-containing sustained release tablet and method for producing the same
JP2013129604A (en) * 2011-12-20 2013-07-04 Kowa Co Sustained release film preparation containing glaucoma treating agent

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