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JPS5334784A - Nnsubstitued quinazoline - Google Patents

Nnsubstitued quinazoline

Info

Publication number
JPS5334784A
JPS5334784A JP8402477A JP8402477A JPS5334784A JP S5334784 A JPS5334784 A JP S5334784A JP 8402477 A JP8402477 A JP 8402477A JP 8402477 A JP8402477 A JP 8402477A JP S5334784 A JPS5334784 A JP S5334784A
Authority
JP
Japan
Prior art keywords
nnsubstitued
quinazoline
nnsubstitued quinazoline
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP8402477A
Other languages
English (en)
Inventor
Binsento Mishieru
Rumondo Jiyorujie
Robi Mishieru
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Science Union et Cie
Original Assignee
Science Union et Cie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Science Union et Cie filed Critical Science Union et Cie
Publication of JPS5334784A publication Critical patent/JPS5334784A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10—Spiro-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56—Nitrogen atoms
    • C07D211/58—Nitrogen atoms attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D211/74—Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP8402477A 1976-07-14 1977-07-13 Nnsubstitued quinazoline Pending JPS5334784A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB29317/76A GB1583753A (en) 1976-07-14 1976-07-14 Piperidine derivatives processes for their preparation and pharmaceutical compositions containing them

Publications (1)

Publication Number Publication Date
JPS5334784A true JPS5334784A (en) 1978-03-31

Family

ID=10289639

Family Applications (1)

Application Number Title Priority Date Filing Date
JP8402477A Pending JPS5334784A (en) 1976-07-14 1977-07-13 Nnsubstitued quinazoline

Country Status (12)

Country Link
US (1) US4166117A (ja)
JP (1) JPS5334784A (ja)
BE (1) BE856784A (ja)
CA (1) CA1103671A (ja)
CH (1) CH625518A5 (ja)
DE (1) DE2731299A1 (ja)
ES (2) ES460699A1 (ja)
FR (1) FR2361385A1 (ja)
GB (1) GB1583753A (ja)
NL (1) NL7707785A (ja)
OA (1) OA05707A (ja)
SU (1) SU751324A3 (ja)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994019342A1 (en) * 1993-02-18 1994-09-01 Kyowa Hakko Kogyo Co., Ltd. Adenosine incorporation inhibitor
JP2008156358A (ja) * 2004-02-13 2008-07-10 Banyu Pharmaceut Co Ltd 縮環４−オキソ−ピリミジン誘導体

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3066434D1 (en) * 1979-11-21 1984-03-08 Kyowa Hakko Kogyo Kk Novel piperidine derivatives, method for the preparation thereof and pharmaceutical compositions containing them
US4344945A (en) * 1980-03-10 1982-08-17 Kyowa Hakko Kogyo Co., Ltd. Piperidine derivatives
US4684654A (en) * 1985-08-14 1987-08-04 American Cyanamid Company 3-heteroalkyl-2,4-quinzaolinediones
PH23565A (en) * 1986-09-05 1989-08-25 Sumitomo Chemical Co Novel pyrimidinylpyrimidine derivatives and a plant disease protectant containing them as the active ingredient
FI95572C (fi) * 1987-06-22 1996-02-26 Eisai Co Ltd Menetelmä lääkeaineena käyttökelpoisen piperidiinijohdannaisten tai sen farmaseuttisen suolan valmistamiseksi
JP2959765B2 (ja) * 1997-12-12 1999-10-06 日本たばこ産業株式会社 ３−ピペリジル−４−オキソキナゾリン誘導体及びそれを含有してなる医薬組成物
US6258819B1 (en) * 1999-08-05 2001-07-10 Syntex (U.S.A.) Llc Substituted 2(4-piperidyl)-4(3H)-quinazolinones and 2-(4-piperidyl)-4(3H)-azaquinazolinones
TW200836743A (en) * 2007-01-29 2008-09-16 Xenon Pharmaceuticals Inc Quinazolinone and fused pyrimidinone compounds and their use in treating sodium channel-mediated diseases or conditions
WO2014102592A2 (en) 2012-12-27 2014-07-03 Purdue Pharma L.P. Oxime/substituted quinoxaline-type piperidine compounds and uses thereof
JO3512B1 (ar) 2014-03-26 2020-07-05 Astex Therapeutics Ltd مشتقات كينوكسالين مفيدة كمعدلات لإنزيم fgfr كيناز
SI3353164T1 (sl) 2015-09-23 2022-02-28 Janssen Pharmaceutica, N.V. Bi-heteroaril substituiran 1,4-benzodiazepini in njihove uporabe za zdravljenje raka
EP3353177B1 (en) 2015-09-23 2020-06-03 Janssen Pharmaceutica NV Tricyclic heterocycles for the treatment of cancer

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2694711A (en) * 1952-12-02 1954-11-16 American Cyanamid Co Quinazolone antimalarial compounds
US3086910A (en) * 1960-03-09 1963-04-23 Wallace & Tiernan Inc Central nervous system depressants 3-(2'-pyridyl)-4-quinazolones
US3257397A (en) * 1963-07-26 1966-06-21 Rexall Drug Chemical Substituted 2, 3-dihydro-4(1h)-quinazolinones
US4027028A (en) * 1975-11-10 1977-05-31 Science Union Et Cie Arylethers and pharmaceutical compositions

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994019342A1 (en) * 1993-02-18 1994-09-01 Kyowa Hakko Kogyo Co., Ltd. Adenosine incorporation inhibitor
JP2008156358A (ja) * 2004-02-13 2008-07-10 Banyu Pharmaceut Co Ltd 縮環４−オキソ−ピリミジン誘導体

Also Published As

Publication number Publication date
BE856784A (fr) 1978-01-13
CA1103671A (fr) 1981-06-23
ES472563A1 (es) 1979-10-16
FR2361385A1 (fr) 1978-03-10
US4166117A (en) 1979-08-28
GB1583753A (en) 1981-02-04
SU751324A3 (ru) 1980-07-23
NL7707785A (nl) 1978-01-17
DE2731299A1 (de) 1978-01-19
OA05707A (fr) 1981-05-31
FR2361385B1 (ja) 1983-10-07
ES460699A1 (es) 1978-12-01
CH625518A5 (ja) 1981-09-30

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