JP2007500027A - 生物医学的な使用のための複合マトリックス - Google Patents
生物医学的な使用のための複合マトリックス Download PDFInfo
- Publication number
- JP2007500027A JP2007500027A JP2006521630A JP2006521630A JP2007500027A JP 2007500027 A JP2007500027 A JP 2007500027A JP 2006521630 A JP2006521630 A JP 2006521630A JP 2006521630 A JP2006521630 A JP 2006521630A JP 2007500027 A JP2007500027 A JP 2007500027A
- Authority
- JP
- Japan
- Prior art keywords
- polymer
- matrix
- cross
- molecular weight
- moles
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Images
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
- A61K31/728—Hyaluronic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
- C08B37/0024—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid beta-D-Glucans; (beta-1,3)-D-Glucans, e.g. paramylon, coriolan, sclerotan, pachyman, callose, scleroglucan, schizophyllan, laminaran, lentinan or curdlan; (beta-1,6)-D-Glucans, e.g. pustulan; (beta-1,4)-D-Glucans; (beta-1,3)(beta-1,4)-D-Glucans, e.g. lichenan; Derivatives thereof
- C08B37/0027—2-Acetamido-2-deoxy-beta-glucans; Derivatives thereof
- C08B37/003—Chitin, i.e. 2-acetamido-2-deoxy-(beta-1,4)-D-glucan or N-acetyl-beta-1,4-D-glucosamine; Chitosan, i.e. deacetylated product of chitin or (beta-1,4)-D-glucosamine; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
- C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
- C08B37/0072—Hyaluronic acid, i.e. HA or hyaluronan; Derivatives thereof, e.g. crosslinked hyaluronic acid (hylan) or hyaluronates
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
- C08L5/08—Chitin; Chondroitin sulfate; Hyaluronic acid; Derivatives thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Polymers & Plastics (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Materials Engineering (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Physical Education & Sports Medicine (AREA)
- Dermatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Immunology (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Materials For Medical Uses (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Medicinal Preparation (AREA)
- Biological Depolymerization Polymers (AREA)
- Polyesters Or Polycarbonates (AREA)
- Compositions Of Macromolecular Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0309401 | 2003-07-30 | ||
PCT/FR2004/002052 WO2005012364A2 (fr) | 2003-07-30 | 2004-07-30 | Matrice complexe a usage biomedical |
Publications (1)
Publication Number | Publication Date |
---|---|
JP2007500027A true JP2007500027A (ja) | 2007-01-11 |
Family
ID=34112706
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2006521630A Pending JP2007500027A (ja) | 2003-07-30 | 2004-07-30 | 生物医学的な使用のための複合マトリックス |
Country Status (10)
Country | Link |
---|---|
US (1) | US20060246137A1 (ru) |
EP (1) | EP1648942A2 (ru) |
JP (1) | JP2007500027A (ru) |
KR (1) | KR20070012306A (ru) |
CN (1) | CN1829743B (ru) |
AU (1) | AU2004261752B2 (ru) |
BR (1) | BRPI0413086A (ru) |
CA (1) | CA2534033A1 (ru) |
RU (1) | RU2360928C2 (ru) |
WO (1) | WO2005012364A2 (ru) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2010036032A (ja) * | 2008-08-01 | 2010-02-18 | Anteis Sa | 高い残留性及び容量を与える高い能力を有する注入可能なヒドロゲル |
JP2011529762A (ja) * | 2008-08-04 | 2011-12-15 | アラーガン・アンデュストリー・ソシエテ・パール・アクシオン・サンプリフィエ | 麻酔剤を含有するヒアルロン酸系ゲル |
JP2013063943A (ja) * | 2011-09-16 | 2013-04-11 | China Medical Univ | 炎症を抑制するための医薬組成物、及び方法 |
Families Citing this family (62)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7338433B2 (en) | 2002-08-13 | 2008-03-04 | Allergan, Inc. | Remotely adjustable gastric banding method |
EP1553878B1 (en) | 2002-08-28 | 2010-02-24 | Allergan, Inc. | Fatigue-resistant gastric banding device |
FR2861734B1 (fr) | 2003-04-10 | 2006-04-14 | Corneal Ind | Reticulation de polysaccharides de faible et forte masse moleculaire; preparation d'hydrogels monophasiques injectables; polysaccharides et hydrogels obtenus |
PT2399528E (pt) | 2004-01-23 | 2013-02-26 | Allergan Inc | Banda gástrica regulável de uma só peça, que pode ser fixada de forma amovível |
DK1725193T3 (da) | 2004-03-08 | 2009-11-30 | Allergan Medical S A | Lukkesystem til rörformede organer |
BRPI0418661A (pt) | 2004-03-18 | 2008-06-10 | Allergan Inc | aparelho e método para ajuste de volume de balões intragástricos |
US8251888B2 (en) | 2005-04-13 | 2012-08-28 | Mitchell Steven Roslin | Artificial gastric valve |
US7798954B2 (en) | 2006-01-04 | 2010-09-21 | Allergan, Inc. | Hydraulic gastric band with collapsible reservoir |
US8043206B2 (en) | 2006-01-04 | 2011-10-25 | Allergan, Inc. | Self-regulating gastric band with pressure data processing |
JP5317058B2 (ja) | 2006-03-08 | 2013-10-16 | ピュラック バイオケム ビー. ブイ. | 有機アミン−乳酸錯体の調製方法 |
FR2909285A1 (fr) * | 2006-12-01 | 2008-06-06 | Anteis Sa | "utilisation d'un gel anti-adhesif et anti fibrotique" |
JP2010528046A (ja) | 2007-05-23 | 2010-08-19 | アラーガン、インコーポレイテッド | 架橋コラーゲンおよびその使用 |
US8318695B2 (en) | 2007-07-30 | 2012-11-27 | Allergan, Inc. | Tunably crosslinked polysaccharide compositions |
US8697044B2 (en) * | 2007-10-09 | 2014-04-15 | Allergan, Inc. | Crossed-linked hyaluronic acid and collagen and uses thereof |
EP2818184B1 (en) | 2007-11-16 | 2018-10-31 | Allergan, Inc. | Compositions and methods for treating Purpura |
US8394784B2 (en) | 2007-11-30 | 2013-03-12 | Allergan, Inc. | Polysaccharide gel formulation having multi-stage bioactive agent delivery |
US8394782B2 (en) | 2007-11-30 | 2013-03-12 | Allergan, Inc. | Polysaccharide gel formulation having increased longevity |
AU2015252122A1 (en) * | 2008-08-04 | 2015-11-26 | Allergan Industrie Sas | Hyaluronic acid-based gels including anesthetic agents |
CA2735173C (en) | 2008-09-02 | 2017-01-10 | Tautona Group Lp | Threads of hyaluronic acid and/or derivatives thereof, methods of making thereof and uses thereof |
US20100305397A1 (en) * | 2008-10-06 | 2010-12-02 | Allergan Medical Sarl | Hydraulic-mechanical gastric band |
EP2362762A1 (en) | 2008-10-06 | 2011-09-07 | Allergan Medical Sàrl | Mechanical gastric band with cushions |
US20100185049A1 (en) | 2008-10-22 | 2010-07-22 | Allergan, Inc. | Dome and screw valves for remotely adjustable gastric banding systems |
FR2938187B1 (fr) | 2008-11-07 | 2012-08-17 | Anteis Sa | Composition injectable a base d'acide hyaluronique ou l'un de ses sels, de polyols et de lidocaine, sterilisee a la chaleur |
ES2662064T3 (es) * | 2009-03-30 | 2018-04-05 | Scivision Biotech Inc. | Método para producir ácido hialurónico reticulado |
US9371402B2 (en) | 2009-04-09 | 2016-06-21 | Scivision Biotech Inc. | Method for producing cross-linked hyaluronic acid |
US8390326B2 (en) * | 2009-05-05 | 2013-03-05 | William Marsh Rice University | Method for fabrication of a semiconductor element and structure thereof |
US9114188B2 (en) | 2010-01-13 | 2015-08-25 | Allergan, Industrie, S.A.S. | Stable hydrogel compositions including additives |
US20110172180A1 (en) | 2010-01-13 | 2011-07-14 | Allergan Industrie. Sas | Heat stable hyaluronic acid compositions for dermatological use |
US8758221B2 (en) | 2010-02-24 | 2014-06-24 | Apollo Endosurgery, Inc. | Source reservoir with potential energy for remotely adjustable gastric banding system |
US8840541B2 (en) * | 2010-02-25 | 2014-09-23 | Apollo Endosurgery, Inc. | Pressure sensing gastric banding system |
KR101764451B1 (ko) | 2010-03-12 | 2017-08-02 | 알러간 인더스트리 에스에이에스 | 피부 상태 개선을 위한 히알루론안 폴리머 및 만니톨을 포함하는 유체 조성물 |
WO2011119468A1 (en) | 2010-03-22 | 2011-09-29 | Allergan, Inc. | Polysaccharide and protein-polysaccharide cross-linked hydrogels for soft tissue augmentation |
US9028394B2 (en) | 2010-04-29 | 2015-05-12 | Apollo Endosurgery, Inc. | Self-adjusting mechanical gastric band |
US9044298B2 (en) | 2010-04-29 | 2015-06-02 | Apollo Endosurgery, Inc. | Self-adjusting gastric band |
US20110270024A1 (en) | 2010-04-29 | 2011-11-03 | Allergan, Inc. | Self-adjusting gastric band having various compliant components |
US20110270025A1 (en) | 2010-04-30 | 2011-11-03 | Allergan, Inc. | Remotely powered remotely adjustable gastric band system |
US8517915B2 (en) | 2010-06-10 | 2013-08-27 | Allergan, Inc. | Remotely adjustable gastric banding system |
US8697057B2 (en) | 2010-08-19 | 2014-04-15 | Allergan, Inc. | Compositions and soft tissue replacement methods |
US9005605B2 (en) | 2010-08-19 | 2015-04-14 | Allergan, Inc. | Compositions and soft tissue replacement methods |
US8889123B2 (en) | 2010-08-19 | 2014-11-18 | Allergan, Inc. | Compositions and soft tissue replacement methods |
US8883139B2 (en) | 2010-08-19 | 2014-11-11 | Allergan Inc. | Compositions and soft tissue replacement methods |
US20120059216A1 (en) | 2010-09-07 | 2012-03-08 | Allergan, Inc. | Remotely adjustable gastric banding system |
US8961393B2 (en) | 2010-11-15 | 2015-02-24 | Apollo Endosurgery, Inc. | Gastric band devices and drive systems |
US20130096081A1 (en) | 2011-06-03 | 2013-04-18 | Allergan, Inc. | Dermal filler compositions |
US9393263B2 (en) | 2011-06-03 | 2016-07-19 | Allergan, Inc. | Dermal filler compositions including antioxidants |
US9408797B2 (en) | 2011-06-03 | 2016-08-09 | Allergan, Inc. | Dermal filler compositions for fine line treatment |
CA2838237C (en) | 2011-06-03 | 2020-05-26 | Allergan, Inc. | Dermal filler compositions including antioxidants |
US9662422B2 (en) | 2011-09-06 | 2017-05-30 | Allergan, Inc. | Crosslinked hyaluronic acid-collagen gels for improving tissue graft viability and soft tissue augmentation |
US20130244943A1 (en) | 2011-09-06 | 2013-09-19 | Allergan, Inc. | Hyaluronic acid-collagen matrices for dermal filling and volumizing applications |
FR2983483B1 (fr) | 2011-12-02 | 2014-11-14 | Vivacy Lab | Procede de substitution et reticulation simultanees d'un polysaccharide via ses fonctions hydroxyles |
US8876694B2 (en) | 2011-12-07 | 2014-11-04 | Apollo Endosurgery, Inc. | Tube connector with a guiding tip |
US8961394B2 (en) | 2011-12-20 | 2015-02-24 | Apollo Endosurgery, Inc. | Self-sealing fluid joint for use with a gastric band |
CN102863631B (zh) * | 2012-09-29 | 2013-11-13 | 杭州嘉伟生物制品有限公司 | 外科整形用组织填充剂交联透明质酸钠凝胶及其制备方法 |
EP3049055B1 (en) | 2013-09-27 | 2018-04-25 | Anteis S.A. | Method for obtaining an injectable hydrogel based on hyaluronic acid containing lidocaine added in powder form, and an alkaline agent, sterilized with heat |
CZ308492B6 (cs) * | 2013-10-25 | 2020-09-23 | Contipro A.S. | Kosmetická kompozice na bázi kyseliny hyaluronové, způsob její přípravy a použití |
CN106661133A (zh) * | 2014-05-29 | 2017-05-10 | 盖尔德玛公司 | 与右旋糖酐接枝的交联的透明质酸 |
US10722444B2 (en) | 2014-09-30 | 2020-07-28 | Allergan Industrie, Sas | Stable hydrogel compositions including additives |
EP3040348A1 (en) | 2014-12-29 | 2016-07-06 | Galderma S.A. | Graft copolymer |
WO2016128783A1 (en) | 2015-02-09 | 2016-08-18 | Allergan Industrie Sas | Compositions and methods for improving skin appearance |
JP7274817B2 (ja) | 2015-02-13 | 2023-05-17 | アラーガン・アンデュストリー・ソシエテ・パール・アクシオン・サンプリフィエ | 顎先等の顔面の容貌を造形し、拡張し、または補正するためのインプラント |
CZ306662B6 (cs) * | 2015-06-26 | 2017-04-26 | Contipro A.S. | Deriváty sulfatovaných polysacharidů, způsob jejich přípravy, způsob jejich modifikace a použití |
KR20180027126A (ko) | 2016-09-06 | 2018-03-14 | (주)한국비엠아이 | 가교화 히알루론산 유도체 매트릭스가 포함된 지혈 조성물 |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS61138601A (ja) * | 1984-12-06 | 1986-06-26 | バイオマトリツクス,インコ−ポレイテツド | 架橋ヒアルロン酸ゲル組成物 |
JPS63105003A (ja) * | 1986-10-13 | 1988-05-10 | フィディーア・ソシエタ・ペル・アチオニ | ヒアルロン酸の架橋エステル |
JPH0912603A (ja) * | 1995-06-22 | 1997-01-14 | Hercules Inc | 酸化防止剤グラフト多糖類及びそれらの用途 |
JPH10324701A (ja) * | 1988-05-13 | 1998-12-08 | Fidia Spa | 架橋したカルボキシ多糖類 |
JP2002536465A (ja) * | 1999-02-05 | 2002-10-29 | ビトロライフ ユーケイ リミティッド | ヒアルロン酸をポリマーに架橋する方法 |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4582640A (en) * | 1982-03-08 | 1986-04-15 | Collagen Corporation | Injectable cross-linked collagen implant material |
US4605691A (en) * | 1984-12-06 | 1986-08-12 | Biomatrix, Inc. | Cross-linked gels of hyaluronic acid and products containing such gels |
US4851521A (en) * | 1985-07-08 | 1989-07-25 | Fidia, S.P.A. | Esters of hyaluronic acid |
SE452469B (sv) * | 1986-06-18 | 1987-11-30 | Pharmacia Ab | Material bestaende av en tverbunden karboxylgrupphaltig polysackarid och forfarande vid framstellning av detsamma |
JPH01265970A (ja) * | 1988-04-19 | 1989-10-24 | Shiseido Co Ltd | ヒアルロン酸を含有させたコラーゲン水溶液又は水分散液 |
DE3841401A1 (de) * | 1988-12-08 | 1990-06-13 | Martin Lemperle | Alloplastisches implantat |
US7060287B1 (en) * | 1992-02-11 | 2006-06-13 | Bioform Inc. | Tissue augmentation material and method |
US5451406A (en) * | 1994-07-14 | 1995-09-19 | Advanced Uroscience, Inc. | Tissue injectable composition and method of use |
US5827937A (en) * | 1995-07-17 | 1998-10-27 | Q Med Ab | Polysaccharide gel composition |
US5792478A (en) * | 1996-07-08 | 1998-08-11 | Advanced Uro Science | Tissue injectable composition and method of use |
DE69822285T2 (de) * | 1998-02-27 | 2005-01-27 | Stichting Hyppomedics | Verfahren zur Herstellung von vernetzter Hyaluronsäure |
FR2811996B1 (fr) * | 2000-07-19 | 2003-08-08 | Corneal Ind | Reticulation de polysaccharide(s), preparation d'hydrogel(s) ; polysaccharide(s) et hydrogel(s) obtenus,leurs utilisations |
US20020025340A1 (en) * | 2000-08-30 | 2002-02-28 | Dyer Wallace K. | Methods and compositions for tissue augmentation |
WO2003072143A1 (en) * | 2002-02-27 | 2003-09-04 | Pharmain, Ltd. | Compositions for delivery of therapeutics and other materials, and methods of making and using the same |
-
2004
- 2004-07-30 AU AU2004261752A patent/AU2004261752B2/en not_active Ceased
- 2004-07-30 BR BRPI0413086-3A patent/BRPI0413086A/pt not_active IP Right Cessation
- 2004-07-30 US US10/565,442 patent/US20060246137A1/en not_active Abandoned
- 2004-07-30 KR KR1020067002010A patent/KR20070012306A/ko not_active Ceased
- 2004-07-30 WO PCT/FR2004/002052 patent/WO2005012364A2/fr active Application Filing
- 2004-07-30 CN CN2004800216528A patent/CN1829743B/zh not_active Expired - Fee Related
- 2004-07-30 CA CA002534033A patent/CA2534033A1/fr not_active Abandoned
- 2004-07-30 RU RU2006102198/04A patent/RU2360928C2/ru not_active IP Right Cessation
- 2004-07-30 EP EP04786014A patent/EP1648942A2/fr not_active Withdrawn
- 2004-07-30 JP JP2006521630A patent/JP2007500027A/ja active Pending
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS61138601A (ja) * | 1984-12-06 | 1986-06-26 | バイオマトリツクス,インコ−ポレイテツド | 架橋ヒアルロン酸ゲル組成物 |
JPS63105003A (ja) * | 1986-10-13 | 1988-05-10 | フィディーア・ソシエタ・ペル・アチオニ | ヒアルロン酸の架橋エステル |
JPH10324701A (ja) * | 1988-05-13 | 1998-12-08 | Fidia Spa | 架橋したカルボキシ多糖類 |
JPH0912603A (ja) * | 1995-06-22 | 1997-01-14 | Hercules Inc | 酸化防止剤グラフト多糖類及びそれらの用途 |
JP2002536465A (ja) * | 1999-02-05 | 2002-10-29 | ビトロライフ ユーケイ リミティッド | ヒアルロン酸をポリマーに架橋する方法 |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2010036032A (ja) * | 2008-08-01 | 2010-02-18 | Anteis Sa | 高い残留性及び容量を与える高い能力を有する注入可能なヒドロゲル |
JP2011529762A (ja) * | 2008-08-04 | 2011-12-15 | アラーガン・アンデュストリー・ソシエテ・パール・アクシオン・サンプリフィエ | 麻酔剤を含有するヒアルロン酸系ゲル |
JP2011529763A (ja) * | 2008-08-04 | 2011-12-15 | アラーガン・アンデュストリー・ソシエテ・パール・アクシオン・サンプリフィエ | 麻酔剤を含有するヒアルロン酸系ゲル |
JP2013063943A (ja) * | 2011-09-16 | 2013-04-11 | China Medical Univ | 炎症を抑制するための医薬組成物、及び方法 |
US8835405B2 (en) | 2011-09-16 | 2014-09-16 | China Medical University | Inhibiting arthritis via injection of synergistic combination of hyaluronic acid and vitamin C and/or vitamin E |
Also Published As
Publication number | Publication date |
---|---|
CA2534033A1 (fr) | 2005-02-10 |
CN1829743A (zh) | 2006-09-06 |
RU2360928C2 (ru) | 2009-07-10 |
US20060246137A1 (en) | 2006-11-02 |
WO2005012364A3 (fr) | 2005-06-02 |
AU2004261752A1 (en) | 2005-02-10 |
KR20070012306A (ko) | 2007-01-25 |
WO2005012364A2 (fr) | 2005-02-10 |
RU2006102198A (ru) | 2007-08-20 |
EP1648942A2 (fr) | 2006-04-26 |
BRPI0413086A (pt) | 2006-10-03 |
AU2004261752B2 (en) | 2010-10-28 |
CN1829743B (zh) | 2010-06-30 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
JP2007500027A (ja) | 生物医学的な使用のための複合マトリックス | |
ES2354699T3 (es) | Gel reticulado biocompatible. | |
JP5571562B2 (ja) | 生分解性の単一相結着性親水ゲル | |
EP2498764B1 (en) | Fragmented hydrogels | |
EP2643029B1 (en) | Preparation and/or formulation of proteins cross-linked with polysaccharides | |
JP5574083B2 (ja) | 高い残留性及び容量を与える高い能力を有する注入可能なヒドロゲル | |
CN108289825A (zh) | 含透明质酸衍生物和dna片段的注射用透明质酸组合物及其应用 | |
US20160015858A1 (en) | Timing controlled in-situ cross-linking of halyuronic acid during injection | |
US9220807B2 (en) | Non-toxic cross-linker for hyaluronic acid | |
WO2014169300A1 (en) | Non-toxic cross-linker for halyuronic acid | |
MXPA06001060A (en) | Complex matrix for biomedical use | |
Ghosh et al. | Exploring the natural polysaccharide-based self-healing polymers for biomedical application | |
Mohite et al. | Polymeric Hydrogels in Medicine | |
Russo et al. | Hyaluronic acid: regenerative medicine and drug delivery | |
HK40078732A (en) | Preparation and/or formulation of proteins cross-linked with polysaccharides | |
HK40009300A (en) | Preparation and/or formulation of proteins cross-linked with polysaccharides | |
HK40009300B (en) | Preparation and/or formulation of proteins cross-linked with polysaccharides | |
HK1150772B (en) | Biodegradable single-phase cohesive hydrogel |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20070725 |
|
A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20110119 |
|
A02 | Decision of refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A02 Effective date: 20110914 |