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Publication number
JP2003503732A5
JP2003503732A5 JP2001508036A JP2001508036A JP2003503732A5 JP 2003503732 A5 JP2003503732 A5 JP 2003503732A5 JP 2001508036 A JP2001508036 A JP 2001508036A JP 2001508036 A JP2001508036 A JP 2001508036A JP 2003503732 A5 JP2003503732 A5 JP 2003503732A5
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JP
Japan
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JP2001508036A
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JP2003503732A (ja
JP4684507B2 (ja
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Priority claimed from GBGB9915703.4A external-priority patent/GB9915703D0/en
Priority claimed from GB0011420A external-priority patent/GB0011420D0/en
Application filed filed Critical
Priority claimed from PCT/EP2000/006238 external-priority patent/WO2001002839A1/en
Publication of JP2003503732A publication Critical patent/JP2003503732A/ja
Publication of JP2003503732A5 publication Critical patent/JP2003503732A5/ja
Application granted granted Critical
Publication of JP4684507B2 publication Critical patent/JP4684507B2/ja
Anticipated expiration legal-status Critical
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JP2001508036A 1999-07-05 2000-07-03 センサープラットホームを使用する方法 Expired - Fee Related JP4684507B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB9915703.4 1999-07-05
GBGB9915703.4A GB9915703D0 (en) 1999-07-05 1999-07-05 Analysis of samples
GB0011420.7 2000-05-11
GB0011420A GB0011420D0 (en) 2000-05-11 2000-05-11 Device
PCT/EP2000/006238 WO2001002839A1 (en) 1999-07-05 2000-07-03 Sensor platform, apparatus incorporating the platform, and process using the platform

Publications (3)

Publication Number Publication Date
JP2003503732A JP2003503732A (ja) 2003-01-28
JP2003503732A5 true JP2003503732A5 (ja) 2007-05-31
JP4684507B2 JP4684507B2 (ja) 2011-05-18

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JP2001508036A Expired - Fee Related JP4684507B2 (ja) 1999-07-05 2000-07-03 センサープラットホームを使用する方法

Country Status (14)

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US (1) US6707561B1 (ja)
EP (1) EP1192448B1 (ja)
JP (1) JP4684507B2 (ja)
KR (1) KR100883079B1 (ja)
CN (1) CN100397068C (ja)
AT (1) ATE340996T1 (ja)
AU (1) AU5824300A (ja)
CY (1) CY1107541T1 (ja)
DE (1) DE60030978T2 (ja)
DK (1) DK1192448T3 (ja)
ES (1) ES2273704T3 (ja)
HK (1) HK1046438B (ja)
PT (1) PT1192448E (ja)
WO (1) WO2001002839A1 (ja)

Families Citing this family (136)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6771376B2 (en) 1999-07-05 2004-08-03 Novartis Ag Sensor platform, apparatus incorporating the platform, and process using the platform
DE60030978T2 (de) 1999-07-05 2007-06-14 Novartis Ag Verfahren zur anwendung einer sensoreinheit
US8111401B2 (en) 1999-11-05 2012-02-07 Robert Magnusson Guided-mode resonance sensors employing angular, spectral, modal, and polarization diversity for high-precision sensing in compact formats
US7167615B1 (en) * 1999-11-05 2007-01-23 Board Of Regents, The University Of Texas System Resonant waveguide-grating filters and sensors and methods for making and using same
JP2003531372A (ja) * 2000-04-14 2003-10-21 ツェプトゼンス アクチエンゲゼルシャフト 励起フィールドを強化するための格子導波路構造及びその使用
US7807447B1 (en) 2000-08-25 2010-10-05 Merck Sharp & Dohme Corp. Compositions and methods for exon profiling
US7575939B2 (en) * 2000-10-30 2009-08-18 Sru Biosystems, Inc. Optical detection of label-free biomolecular interactions using microreplicated plastic sensor elements
US7101660B2 (en) * 2000-10-30 2006-09-05 Sru Biosystems, Inc. Method for producing a colorimetric resonant reflection biosensor on rigid surfaces
US7300803B2 (en) * 2000-10-30 2007-11-27 Sru Biosystems, Inc. Label-free methods for performing assays using a colorimetric resonant reflectance optical biosensor
US20030092075A1 (en) * 2000-10-30 2003-05-15 Sru Biosystems, Llc Aldehyde chemical surface activation processes and test methods for colorimetric resonant sensors
US7175980B2 (en) 2000-10-30 2007-02-13 Sru Biosystems, Inc. Method of making a plastic colorimetric resonant biosensor device with liquid handling capabilities
US7306827B2 (en) * 2000-10-30 2007-12-11 Sru Biosystems, Inc. Method and machine for replicating holographic gratings on a substrate
US7875434B2 (en) * 2000-10-30 2011-01-25 Sru Biosystems, Inc. Label-free methods for performing assays using a colorimetric resonant reflectance optical biosensor
US7142296B2 (en) * 2000-10-30 2006-11-28 Sru Biosystems, Inc. Method and apparatus for detecting biomolecular interactions
US20030113766A1 (en) * 2000-10-30 2003-06-19 Sru Biosystems, Llc Amine activated colorimetric resonant biosensor
US7615339B2 (en) 2000-10-30 2009-11-10 Sru Biosystems, Inc. Method for producing a colorimetric resonant reflection biosensor on rigid surfaces
US7094595B2 (en) * 2000-10-30 2006-08-22 Sru Biosystems, Inc. Label-free high-throughput optical technique for detecting biomolecular interactions
US7153702B2 (en) * 2000-10-30 2006-12-26 Sru Biosystems, Inc. Label-free methods for performing assays using a colorimetric resonant reflectance optical biosensor
US7264973B2 (en) * 2000-10-30 2007-09-04 Sru Biosystems, Inc. Label-free methods for performing assays using a colorimetric resonant optical biosensor
US7371562B2 (en) 2000-10-30 2008-05-13 Sru Biosystems, Inc. Guided mode resonant filter biosensor using a linear grating surface structure
US7524625B2 (en) 2000-10-30 2009-04-28 Sru Biosystems, Inc. Real time binding analysis of antigens on a biosensor surface
AU2006201361B2 (en) * 2000-10-30 2009-01-22 Sru Biosystems, Inc. A label-free high-throughput optical technique for detecting biomolecular interactions
US7023544B2 (en) * 2000-10-30 2006-04-04 Sru Biosystems, Inc. Method and instrument for detecting biomolecular interactions
US6951715B2 (en) * 2000-10-30 2005-10-04 Sru Biosystems, Inc. Optical detection of label-free biomolecular interactions using microreplicated plastic sensor elements
US7070987B2 (en) * 2000-10-30 2006-07-04 Sru Biosystems, Inc. Guided mode resonant filter biosensor using a linear grating surface structure
US7217574B2 (en) * 2000-10-30 2007-05-15 Sru Biosystems, Inc. Method and apparatus for biosensor spectral shift detection
US7202076B2 (en) * 2000-10-30 2007-04-10 Sru Biosystems, Inc. Label-free high-throughput optical technique for detecting biomolecular interactions
DE10063151B4 (de) * 2000-12-18 2004-03-25 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Vorrichtung und Verfahren zur Analyse der qualitativen und/oder quantitativen Zusammensetzung von Fluiden
WO2002079765A2 (de) * 2001-04-02 2002-10-10 Zeptosens Ag Optische struktur zur multi-photonen-anregung und deren verwendung
CA2743332A1 (en) * 2001-09-13 2003-03-20 Axela Inc. Method and apparatus for assay based on light diffraction
US6922287B2 (en) 2001-10-12 2005-07-26 Unaxis Balzers Aktiengesellschaft Light coupling element
AU2003210523B2 (en) * 2002-01-28 2008-03-20 Sru Biosystems, Inc. A guided mode resonant filter biosensor using a linear grating surface structure
AU2008202728B2 (en) * 2002-01-28 2011-04-07 Sru Biosystems, Inc. A guided mode resonant filter biosensor using a linear grating surface structure
US7504364B2 (en) 2002-03-01 2009-03-17 Receptors Llc Methods of making arrays and artificial receptors
US7807348B2 (en) * 2002-03-20 2010-10-05 Wisconsin Alumni Research Foundation Optical imaging of nanostructured substrates
US7074311B1 (en) 2002-05-08 2006-07-11 Sru Biosystems Inc. Biosensor electrophoresis
US7429492B2 (en) * 2002-09-09 2008-09-30 Sru Biosystems, Inc. Multiwell plates with integrated biosensors and membranes
US7927822B2 (en) 2002-09-09 2011-04-19 Sru Biosystems, Inc. Methods for screening cells and antibodies
AU2003294535A1 (en) * 2002-12-20 2004-07-14 Fiso Technologies Inc. Polarisation interferometric method and sensor for detecting a chemical substance
EP1606575A4 (en) * 2003-01-27 2006-12-27 Zetetic Inst LICKING GUIDED WAVE MODES USED IN INTERFEROMETRIC CONFOCAL MICROSCOPY FOR MEASURING TRIANGULAR FEATURES
EP1613737A4 (en) 2003-03-28 2008-12-03 Receptors Llc ARTIFICIAL RECEPTORS COMPRISING REVERSIBLE IMMOBILIZED CONSTRUCTION BLOCKS AND METHODS
EP1642114A1 (en) * 2003-06-25 2006-04-05 Koninklijke Philips Electronics N.V. Support with a surface structure for sensitive evanescent-field detection
US20050018944A1 (en) * 2003-07-25 2005-01-27 Mozdy Eric J. Polarization modulation interrogation of grating-coupled waveguide sensors
EP1664780A2 (en) * 2003-09-03 2006-06-07 Receptors LLC Sensors employing combinatorial artificial receptors
CA2537306A1 (en) * 2003-09-03 2005-03-17 Receptors Llc Methods employing combinatorial artificial receptors
US8298780B2 (en) * 2003-09-22 2012-10-30 X-Body, Inc. Methods of detection of changes in cells
US20050111007A1 (en) * 2003-09-26 2005-05-26 Zetetic Institute Catoptric and catadioptric imaging system with pellicle and aperture-array beam-splitters and non-adaptive and adaptive catoptric surfaces
US20050070027A1 (en) 2003-09-30 2005-03-31 Jacques Gollier Double resonance interrogation of grating-coupled waveguides
EP1690092A2 (en) * 2003-12-02 2006-08-16 Receptors LLC Artificial receptors including gradients
KR100579489B1 (ko) * 2003-12-11 2006-05-12 이진우 생체물질 측정장치 및 그 제조방법
EP1710581B1 (en) 2003-12-25 2014-03-19 National Institute of Advanced Industrial Science and Technology Method for analyzing interactions between proteins and sugar chains
US20060068490A1 (en) * 2004-03-05 2006-03-30 Cha-Mei Tang Flow-through chemical and biological sensor
US20050231728A1 (en) * 2004-04-15 2005-10-20 Anbo Wang Q-point stabilization for linear interferometric sensors using tunable diffraction grating
JP4338590B2 (ja) * 2004-06-03 2009-10-07 独立行政法人科学技術振興機構 蛍光相関分光法による抗原の迅速検出及び／又は測定法。
US7270543B2 (en) 2004-06-29 2007-09-18 Therametric Technologies, Inc. Handpiece for caries detection
US20060004526A1 (en) * 2004-07-01 2006-01-05 Ambion, Inc. System and method for processing results of a complex genetic test
WO2006005111A1 (en) * 2004-07-08 2006-01-19 Swinburne University Of Technology Fibre sensor production
TW200607991A (en) * 2004-08-16 2006-03-01 Zetetic Inst Apparatus and method for joint and time delayed measurements of components of conjugated quadratures of fields of reflected/scattered and transmitted/scattered beams by an object in interferometry
WO2006023612A2 (en) * 2004-08-19 2006-03-02 Zetetic Institute Sub-nanometer overlay, critical dimension, and lithography tool projection optic metrology systems based on measurement of exposure induced changes in photoresist on wafers
WO2006029234A1 (en) 2004-09-03 2006-03-16 Receptors Llc Combinatorial artificial receptors including tether building blocks
EP1789792A2 (en) 2004-09-11 2007-05-30 Receptors LLC Combinatorial artificial receptors including peptide building blocks
WO2006034065A2 (en) * 2004-09-20 2006-03-30 Zetetic Institute Catoptric imaging systems comprising pellicle and/or aperture-array beam-splitters and non-adaptive and /or adaptive catoptric surfaces
US7185753B2 (en) * 2004-09-28 2007-03-06 Hartness International, Inc. Shuttle conveyor
EP1817571B1 (en) 2004-11-04 2011-09-07 Renishaw Diagnostics Limited Metal nano-void photonic crystal for enhanced raman spectroscopy
GB0424458D0 (en) * 2004-11-04 2004-12-08 Mesophotonics Ltd Metal nano-void photonic crystal for enhanced raman spectroscopy
CN103558369B (zh) * 2004-12-13 2015-09-09 拜尔保健有限公司 用于测量生物液体中的分析物的自我限定大小的组合物和检验设备
US20060223051A1 (en) * 2005-04-05 2006-10-05 Ye Fang System and method for performing G protein coupled receptor (GPCR) cell assays using waveguide-grating sensors
WO2006108183A2 (en) 2005-04-05 2006-10-12 Corning Incorporated Label free biosensors and cells
US7790406B2 (en) * 2005-08-11 2010-09-07 Sru Biosystems, Inc Grating-based sensor combining label-free binding detection and fluorescence amplification and readout system for sensor
KR101006793B1 (ko) * 2005-08-11 2011-01-10 에스알유 바이오시스템즈, 인코포레이티드 라벨 없는 바인딩 검출 및 형광 증폭과 조합된 격자-기반센서 및 센서를 위한 판독 시스템
US20070036682A1 (en) * 2005-08-15 2007-02-15 Honeywell International Inc. Microoptic glucose detector
EP1991873B1 (en) * 2006-02-21 2013-10-16 Harri HÄRMÄ Separation-free assay method
RU2309959C1 (ru) * 2006-02-22 2007-11-10 Институт Молекулярной Биологии Им. В.А. Энгельгардта Российской Академии Наук Применение немодифицированных полимерных материалов для изготовления подложки биочипов, биочип на их основе и способ его изготовления, способ иммобилизации гидрогелей на немодифицированных полимерных материалах
JP2008102117A (ja) * 2006-09-21 2008-05-01 Fujifilm Corp 表面プラズモン増強蛍光センサおよび蛍光検出方法
KR20090086235A (ko) * 2006-10-31 2009-08-11 에스알유 바이오시스템즈, 인코포레이티드 작용기화된 표면 상에서 비­특이적 단백질 결합을 차단하는 방법
EP2069789A2 (en) 2006-11-21 2009-06-17 Applied Biosystems, LLC Intermediates and methods for forming passivated surfaces on oxide layers and articles produced thereby
US8360771B2 (en) 2006-12-28 2013-01-29 Therametric Technologies, Inc. Handpiece for detection of dental demineralization
US7943908B2 (en) * 2007-01-22 2011-05-17 University Of Maryland Sensor system with surface-plasmon-polariton (SPP) enhanced selective fluorescence excitation and method
US7599055B2 (en) * 2007-02-27 2009-10-06 Corning Incorporated Swept wavelength imaging optical interrogation system and method for using same
JP2008241305A (ja) * 2007-03-26 2008-10-09 Hokkaido Univ 蛍光シグナルの増幅方法
US20080240543A1 (en) * 2007-03-30 2008-10-02 Wolfgang Ernst Gustav Budach Calibration and normalization method for biosensors
CN101743465A (zh) * 2007-04-19 2010-06-16 Sru生物系统公司 应用生物传感器检测与固定化靶标分子直接结合的小分子的方法
EP2064542B1 (en) * 2007-04-19 2011-08-17 Corning Incorporated Live-cell signals of pathogen intrusion and methods thereof
WO2008136812A2 (en) * 2007-05-07 2008-11-13 The Board Of Trustees Of The University Of Illinois Fluorescence detection enhancement using photonic crystal extraction
US9778267B2 (en) 2007-07-11 2017-10-03 X-Body, Inc. Methods for identifying modulators of ion channels
US9134307B2 (en) 2007-07-11 2015-09-15 X-Body, Inc. Method for determining ion channel modulating properties of a test reagent
CN103954595A (zh) * 2007-07-12 2014-07-30 纳米识别技术股份公司 光电传感器系统
DE102007033124B4 (de) * 2007-07-16 2012-12-06 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Vorrichtung zur optischen Detektion von Substanzen in einem flüssigen oder gasförmigen Medium
US20090309617A1 (en) * 2007-08-24 2009-12-17 Ye Fang Biosensor antibody functional mapping
US20090093011A1 (en) * 2007-10-05 2009-04-09 Ye Fang Biosensors for ligand-directed functional selectivity
US20090325211A1 (en) * 2007-10-06 2009-12-31 Ye Fang System and method for dual-detection of a cellular response
US8426148B2 (en) 2007-10-06 2013-04-23 Corning Incorporated Label-free methods using a resonant waveguide grating biosensor to determine GPCR signaling pathways
US8703428B2 (en) * 2007-10-06 2014-04-22 Corning Incorporated Single-cell label-free assay
KR100945387B1 (ko) * 2007-11-14 2010-03-04 서강대학교산학협력단 시료의 비선형계수의 균질성 검사 장치
US20090181409A1 (en) * 2008-01-10 2009-07-16 Ye Fang Optical biosensor method for cell-cell interaction
US8846575B2 (en) 2008-03-05 2014-09-30 Corning Incorporated High-throughput high-information content label-free cell biology screening methods
US8759013B2 (en) 2008-03-05 2014-06-24 Corning Incorporated Dual-target biosensor cell assays
US8313898B2 (en) 2008-03-05 2012-11-20 Corning Incorporated Dual-target biosensor cell assays
JP5094484B2 (ja) * 2008-03-11 2012-12-12 富士フイルム株式会社 蛍光検出方法および蛍光検出装置
EP2108938A1 (en) * 2008-04-09 2009-10-14 Koninklijke Philips Electronics N.V. A carrier for optical detection in small sample volumes
US8257936B2 (en) * 2008-04-09 2012-09-04 X-Body Inc. High resolution label free analysis of cellular properties
US20100015721A1 (en) * 2008-06-04 2010-01-21 Sru Biosystems, Inc. Detection of Promiscuous Small Submicrometer Aggregates
US8173198B2 (en) 2008-07-23 2012-05-08 Life Technologies Corporation Deposition of metal oxides onto surfaces as an immobilization vehicle for carboxylated or phophated particles or polymers
WO2010018002A1 (de) 2008-08-14 2010-02-18 Cytolon Ag Automatisiertes system zur auswahl und vermittlung von gelagerten allogenen biologischen zellen für transplantation, therapie und forschung
KR101226957B1 (ko) * 2008-12-08 2013-02-07 한국전자통신연구원 일회용 진단 키트
CN101769912B (zh) * 2008-12-29 2014-05-28 北京卫星环境工程研究所 卫星整星表面热控材料原位测试探头调整平台
WO2010089158A1 (de) 2009-02-06 2010-08-12 Cytolon Ag Automatisiertes system zum vergleich individueller genom-, transkriptom-, proteom-, epigenom und metabolomdaten mit daten aus knochenmarkspender-registern und blut, nabelschnurblut und gewebebanken
US8498882B2 (en) 2009-02-06 2013-07-30 Cytolon Ag System for making available individual or pooled, also anonymous patient data on the basis of molecular genome, transcriptome, proteome, epigenome, or metabolome data
US20100273185A1 (en) * 2009-04-27 2010-10-28 Sru Biosystems, Inc. Detection of Biased Agonist Activation
KR20120026551A (ko) * 2009-05-15 2012-03-19 에스알유 바이오시스템즈, 인코포레이티드 세포 집단 및 혼합된 세포 집단에서의 변화의 검출 방법
JP5572210B2 (ja) * 2009-05-22 2014-08-13 スリーエム イノベイティブ プロパティズ カンパニー 多層比色センサアレイ
CN101988893B (zh) 2009-07-31 2012-02-08 长春吉大·小天鹅仪器有限公司 48通道阵列式等吸收波长检测系统
CN101788473B (zh) * 2009-12-29 2011-09-07 南京邮电大学 微型自相干生物化学传感器及其检测方法
JP5544653B2 (ja) * 2010-02-02 2014-07-09 独立行政法人産業技術総合研究所 抗原抗体反応の検出方法
DE112011100442A5 (de) 2010-02-05 2013-04-25 Cytolon Ag Automatisiertes system zur auswahl und vermittlung von gelagerten allogenen biologischen zellen für transplantation, therapie und forschung
US20110207789A1 (en) * 2010-02-19 2011-08-25 Ye Fang Methods related to casein kinase ii (ck2) inhibitors and the use of purinosome-disrupting ck2 inhibitors for anti-cancer therapy agents
WO2011120042A1 (en) * 2010-03-26 2011-09-29 Sru Biosystems, Inc. Use of induced pluripotent cells and other cells for screening compound libraries
CN102258855A (zh) * 2010-05-25 2011-11-30 上海薄荷信息科技有限公司 一种智能球类训练系统以及相应的控制方法
ES2616308T3 (es) * 2011-03-17 2017-06-12 Valoya Oy Método para cámaras de crecimiento oscuras
EP2618130A1 (en) * 2012-01-17 2013-07-24 F. Hoffmann-La Roche AG Device for use in the detection of binding affinities
CN103063652B (zh) * 2012-12-31 2014-09-03 济南大学 一种分子印迹电致发光检测抗生素残留的电压可控和多路转换的多通道传感纸芯片的制备
US10330598B2 (en) 2013-12-03 2019-06-25 Koninklijke Philips N.V. Biosensor comprising waveguide
CN105403694B (zh) * 2015-11-05 2017-05-31 合肥学院 一种用于探测百草枯分子的PS@SiO2人工抗体的制备方法
US10712279B2 (en) * 2016-07-22 2020-07-14 Hewlett-Packard Development Company, L.P. Activatable surface enhanced Raman spectroscopy sensor stage
US20180029074A1 (en) * 2016-07-28 2018-02-01 Aculon, Inc. Coated articles having improved stability in aggressive environments
FR3067043B1 (fr) * 2017-06-02 2021-06-25 Univ De Lille 1 Sciences Et Technologies Procede de detection optique
CN107481920B (zh) * 2017-07-21 2020-03-10 上海科技大学 能够利用机械应力诱导细菌形貌伸长的材料及制备和应用
KR20190041306A (ko) 2017-10-12 2019-04-22 주식회사 엘지화학 이종 소재 접합체의 제조방법
CN108344724B (zh) * 2018-02-24 2021-05-04 南京智感环境科技有限公司 一种便携式湿地土壤监测装置
CN108344723B (zh) * 2018-02-24 2021-05-04 南京智感环境科技有限公司 一种湿地土壤的原位同步监测方法
CN108827480B (zh) * 2018-04-11 2020-03-27 山东师范大学 一种基于磷光发射的抗氧干扰温度传感器
CN108802391B (zh) * 2018-08-07 2021-03-16 福建师范大学 一种基于TiO2介晶诱导的共振能量转移型电化学发光及对卵巢癌标记物的免疫传感方法
CN111822063B (zh) * 2019-04-18 2022-04-12 京东方科技集团股份有限公司 一种微流控芯片、其制作方法及微流控装置
CN112694887B (zh) * 2020-12-07 2024-04-26 黑龙江省农业科学院植物保护研究所 一种发光型传感器及其构筑方法与在检测植物水杨酸含量中的应用
CN114236659A (zh) * 2021-12-21 2022-03-25 诚瑞光学(南宁)有限公司 光栅及其制备方法、光波导
US12306442B2 (en) * 2022-08-02 2025-05-20 Globalfoundries U.S. Inc. Structure including grating coupler with optofluidic grating channels

Family Cites Families (75)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0112721B1 (en) * 1982-12-21 1988-05-18 Ares-Serono N.V. Assay technique
DE3568874D1 (en) 1984-06-13 1989-04-20 Ares Serono Inc Photometric instruments, their use in methods of optical analysis, and ancillary devices therefor
GB8423204D0 (en) 1984-09-14 1984-10-17 Comtech Res Unit Assay technique and equipment
GB8618133D0 (en) 1986-07-24 1986-09-03 Pa Consulting Services Biosensors
GB8618159D0 (en) 1986-07-25 1986-09-03 Pa Consulting Services Spectrometer based instruments
IL85137A (en) 1987-01-21 1992-02-16 Ares Serono Res & Dev Ltd Method of assaying for a ligand using surface plasmon resonance effect
CA1305921C (en) * 1987-01-30 1992-08-04 Eric K. Gustafson Diffraction immunoassay and reagents
US4952056A (en) 1988-05-17 1990-08-28 Entwicklungsgemeinschaft Asi Method of determining the autocollimation angle of a grating coupler
GB8812213D0 (en) 1988-05-24 1988-06-29 Ares Serono Res & Dev Ltd Method of assay
GB8822228D0 (en) 1988-09-21 1988-10-26 Southern E M Support-bound oligonucleotides
SE462408B (sv) 1988-11-10 1990-06-18 Pharmacia Ab Optiskt biosensorsystem utnyttjande ytplasmonresonans foer detektering av en specific biomolekyl, saett att kalibrera sensoranordningen samt saett att korrigera foer baslinjedrift i systemet
SE462454B (sv) 1988-11-10 1990-06-25 Pharmacia Ab Maetyta foer anvaendning i biosensorer
SE8804074D0 (sv) 1988-11-10 1988-11-10 Pharmacia Ab Sensorenhet och dess anvaendning i biosensorsystem
SE8902043L (sv) 1988-11-10 1990-05-11 Pharmacia Ab Foerfarande foer karakterisering av makromolekyler
GB2227089A (en) 1989-01-11 1990-07-18 Plessey Co Plc An optical biosensor
US5006716A (en) * 1989-02-22 1991-04-09 Research Corporation Technologies, Inc. Method and system for directional, enhanced fluorescence from molecular layers
AU624944B2 (en) 1989-04-11 1992-06-25 Applied Research Systems Ars Holding N.V. Multianalyte test vehicle
GB8911462D0 (en) 1989-05-18 1989-07-05 Ares Serono Res & Dev Ltd Devices for use in chemical test procedures
US5143854A (en) 1989-06-07 1992-09-01 Affymax Technologies N.V. Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
US5082629A (en) 1989-12-29 1992-01-21 The Board Of The University Of Washington Thin-film spectroscopic sensor
EP0484472B1 (de) 1990-04-12 1997-07-16 SIGRIST, Hans, Dr. Verfahren zur lichtinduzierten immobilisierung von biomolekülen an chemisch "inerten" oberflächen
DE59109246D1 (de) * 1990-05-03 2003-04-03 Hoffmann La Roche Mikrooptischer Sensor
US5830766A (en) 1990-05-23 1998-11-03 Ares-Serono Research & Development Ltd. Partnership Enhanced signal-to-noise ratio and sensitivity optical immunoassay
US5478756A (en) 1990-07-24 1995-12-26 Fisons Plc Chemical sensor for detecting binding reactions
EP0543831B1 (en) 1990-08-17 1995-12-13 FISONS plc Analytical device
DE4026978A1 (de) 1990-08-25 1992-02-27 Bayer Ag Auf traegern angebrachte ein- oder mehrlagige schichtelemente und ihre herstellung
GB9019123D0 (en) 1990-09-01 1990-10-17 Fisons Plc Analytical device
SE501013C2 (sv) 1990-10-01 1994-10-17 Pharmacia Biosensor Ab Förfarande för förbättring av analys med bindning till fast fas
ATE199054T1 (de) 1990-12-06 2001-02-15 Affymetrix Inc A Delaware Corp Verbindungen und ihre verwendung in einer binären synthesestrategie
GB9102646D0 (en) 1991-02-07 1991-03-27 Fisons Plc Analytical device
JPH06504917A (ja) 1991-03-09 1994-06-09 ファイスンズ　ピーエルシー 分析の方法と装置
GB9105031D0 (en) 1991-03-09 1991-04-24 Fisons Plc Processing analytical reagents
GB2256477B (en) 1991-06-07 1995-03-08 Marconi Gec Ltd An optical sensor
DE4121426A1 (de) * 1991-06-28 1993-01-14 Basf Ag Chemischer sensor
DE4228853C2 (de) 1991-09-18 1993-10-21 Schott Glaswerke Optischer Wellenleiter mit einem planaren oder nur geringfügig gewölbten Substrat und Verfahren zu dessen Herstellung sowie Verwendung eines solchen
GB9200564D0 (en) 1992-01-11 1992-03-11 Fisons Plc Analytical device with variable angle of incidence
GB9212416D0 (en) 1992-06-11 1992-07-22 Medical Res Council Reversible binding substances
SE9201984D0 (sv) 1992-06-29 1992-06-29 Pharmacia Biosensor Ab Improvement in optical assays
SE501108C2 (sv) 1993-04-08 1994-11-14 Pharmacia Lkb Biotech Sätt och anordning för bestämning av brytningsindex
JPH09505135A (ja) 1993-05-28 1997-05-20 ファイソンズ ピーエルシー 分析装置
GB9314991D0 (en) * 1993-07-20 1993-09-01 Sandoz Ltd Mechanical device
CA2151960A1 (en) 1993-11-15 1995-05-26 Christof Fattinger System for analysing substances at the surface of an optical sensor
US5631734A (en) 1994-02-10 1997-05-20 Affymetrix, Inc. Method and apparatus for detection of fluorescently labeled materials
US5578832A (en) 1994-09-02 1996-11-26 Affymetrix, Inc. Method and apparatus for imaging a sample on a device
HUT76406A (en) 1994-05-27 1997-08-28 Ciba Geigy Ag Process for detecting evanescently excited luminescence
US5814565A (en) 1995-02-23 1998-09-29 University Of Utah Research Foundation Integrated optic waveguide immunosensor
DE69637315T2 (de) * 1995-05-12 2008-08-28 Novartis Ag Verfahren zur parallelen bestimmung mehrerer analyten mittels evaneszent angeregter lumineszenz
US5545531A (en) 1995-06-07 1996-08-13 Affymax Technologies N.V. Methods for making a device for concurrently processing multiple biological chip assays
US5856174A (en) 1995-06-29 1999-01-05 Affymetrix, Inc. Integrated nucleic acid diagnostic device
SE9502608D0 (sv) 1995-07-14 1995-07-14 Pharmacia Biosensor Ab Method for nucleic acid senquencing
SE9503028D0 (sv) 1995-09-01 1995-09-01 Pharmacia Biosensor Ab Method of analysing chemical and physical interactions at a sensor surface
GB9518429D0 (en) 1995-09-08 1995-11-08 Pharmacia Biosensor A rapid method for providing kinetic and structural data in molecular interaction analysis
SE9504046D0 (sv) 1995-11-14 1995-11-14 Pharmacia Ab Method of determining affinity and kinetic properties
GB9602542D0 (en) 1996-02-08 1996-04-10 Fisons Plc Analytical device
AT403745B (de) 1996-02-29 1998-05-25 Avl Verbrennungskraft Messtech Messanordnung mit einem für anregungs- und messstrahlung transparentem trägerelement
EP0797090A3 (en) 1996-03-19 1997-10-01 Texas Instruments Incorporated Integrally formed surface plasmon resonance sensor
SE9601318D0 (sv) 1996-04-04 1996-04-04 Pharmacia Biosensor Ab Method for nucleic acid analysis
US5981956A (en) 1996-05-16 1999-11-09 Affymetrix, Inc. Systems and methods for detection of labeled materials
US6111248A (en) 1996-10-01 2000-08-29 Texas Instruments Incorporated Self-contained optical sensor system
US5946083A (en) 1997-10-01 1999-08-31 Texas Instruments Incorporated Fixed optic sensor system and distributed sensor network
EP1021708A1 (en) 1996-11-11 2000-07-26 Novartis AG Use of biosensors to diagnose plant diseases
US5846843A (en) * 1996-11-18 1998-12-08 The University Of Toledo Sensor using long range surface plasmon resonance with diffraction double-grating
JP3748571B2 (ja) 1996-11-18 2006-02-22 ノバルティス アクチエンゲゼルシャフト 測定装置及びその使用方法
EP1007969A4 (en) 1996-12-17 2006-12-13 Affymetrix Inc DESIGN OF LITHOGRAPHIC MASKS AND SYNTHESIS OF VARIOUS PROBES ON A SUBSTRATE
US6183696B1 (en) 1997-01-22 2001-02-06 Texas Instruments Incorporated Optically based miniaturized sensor with integrated fluidics
US5898503A (en) 1997-03-19 1999-04-27 Texas Instruments Incorporated Surface plasmon resonance sensor with interchangeable optical element
US6294327B1 (en) 1997-09-08 2001-09-25 Affymetrix, Inc. Apparatus and method for detecting samples labeled with material having strong light scattering properties, using reflection mode light and diffuse scattering
EP1443321A3 (de) 1997-09-10 2005-02-02 Artificial Sensing Instruments ASI AG Optischer Sensor und optisches Verfahren zur Charakterisierung einer chemischen und/oder biochemischen Substanz
US5994150A (en) * 1997-11-19 1999-11-30 Imation Corp. Optical assaying method and system having rotatable sensor disk with multiple sensing regions
US6200814B1 (en) 1998-01-20 2001-03-13 Biacore Ab Method and device for laminar flow on a sensing surface
US6289286B1 (en) 1998-05-29 2001-09-11 Biacore Ab Surface regeneration of biosensors and characterization of biomolecules associated therewith
US6111652A (en) 1998-07-14 2000-08-29 Texas Instruments Incorporated High throughput surface plasmon resonance analysis system
US6203989B1 (en) 1998-09-30 2001-03-20 Affymetrix, Inc. Methods and compositions for amplifying detectable signals in specific binding assays
JP2003501654A (ja) 1999-06-05 2003-01-14 ツェプトゼンス アクチエンゲゼルシャフト 複数の分析対象物の測定のためのセンサプラットフォーム及び方法
DE60030978T2 (de) 1999-07-05 2007-06-14 Novartis Ag Verfahren zur anwendung einer sensoreinheit

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