IL163642A0 - Pharmaceutical formulation of iressa comprising a water-soluble cellulose derivative - Google Patents
Pharmaceutical formulation of iressa comprising a water-soluble cellulose derivativeInfo
- Publication number
- IL163642A0 IL163642A0 IL16364203A IL16364203A IL163642A0 IL 163642 A0 IL163642 A0 IL 163642A0 IL 16364203 A IL16364203 A IL 16364203A IL 16364203 A IL16364203 A IL 16364203A IL 163642 A0 IL163642 A0 IL 163642A0
- Authority
- IL
- Israel
- Prior art keywords
- iressa
- water
- pharmaceutical formulation
- cellulose derivative
- soluble cellulose
- Prior art date
Links
- 239000005411 L01XE02 - Gefitinib Substances 0.000 title 1
- 229920002678 cellulose Polymers 0.000 title 1
- 239000001913 cellulose Substances 0.000 title 1
- XGALLCVXEZPNRQ-UHFFFAOYSA-N gefitinib Chemical compound C=12C=C(OCCCN3CCOCC3)C(OC)=CC2=NC=NC=1NC1=CC=C(F)C(Cl)=C1 XGALLCVXEZPNRQ-UHFFFAOYSA-N 0.000 title 1
- 229940084651 iressa Drugs 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
- C07D239/94—Nitrogen atoms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Inorganic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0204392A GB0204392D0 (en) | 2002-02-26 | 2002-02-26 | Pharmaceutical compound |
GB0212462A GB0212462D0 (en) | 2002-05-30 | 2002-05-30 | Pharmaceutical compound |
GB0213267A GB0213267D0 (en) | 2002-06-11 | 2002-06-11 | Pharmaceutical composition |
PCT/GB2003/000803 WO2003072139A1 (en) | 2002-02-26 | 2003-02-24 | Pharmaceutical formulation of iressa comprising a water-soluble cellulose derivative |
Publications (1)
Publication Number | Publication Date |
---|---|
IL163642A0 true IL163642A0 (en) | 2005-12-18 |
Family
ID=27767732
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL16364203A IL163642A0 (en) | 2002-02-26 | 2003-02-24 | Pharmaceutical formulation of iressa comprising a water-soluble cellulose derivative |
IL163642A IL163642A (en) | 2002-02-26 | 2004-08-19 | Irsa's pharmaceutical preparation contains a water-soluble cellulose derivative |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL163642A IL163642A (en) | 2002-02-26 | 2004-08-19 | Irsa's pharmaceutical preparation contains a water-soluble cellulose derivative |
Country Status (30)
Country | Link |
---|---|
US (2) | US20050163835A1 (pl) |
EP (1) | EP1480679B1 (pl) |
JP (1) | JP4544863B2 (pl) |
KR (2) | KR20100090726A (pl) |
CN (1) | CN1326569C (pl) |
AR (1) | AR038848A1 (pl) |
AT (1) | ATE362771T1 (pl) |
AU (1) | AU2003208444B2 (pl) |
BR (1) | BRPI0307786B8 (pl) |
CA (1) | CA2476587C (pl) |
CO (1) | CO5601038A2 (pl) |
CY (1) | CY1108026T1 (pl) |
DE (1) | DE60313956T2 (pl) |
DK (1) | DK1480679T3 (pl) |
ES (1) | ES2286406T3 (pl) |
HK (1) | HK1070585A1 (pl) |
IL (2) | IL163642A0 (pl) |
IS (1) | IS2462B (pl) |
MX (1) | MXPA04008307A (pl) |
MY (1) | MY135609A (pl) |
NO (1) | NO328658B1 (pl) |
NZ (1) | NZ534513A (pl) |
PL (1) | PL208114B1 (pl) |
PT (1) | PT1480679E (pl) |
RU (1) | RU2318518C2 (pl) |
SA (1) | SA03240043B1 (pl) |
TW (1) | TWI271193B (pl) |
UA (1) | UA76325C2 (pl) |
UY (1) | UY27682A1 (pl) |
WO (1) | WO2003072139A1 (pl) |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE60332322D1 (de) | 2002-02-26 | 2010-06-10 | Astrazeneca Ab | Neue kristalline formen der krebsbekämpfenden verbindung zd1839 |
GB0317663D0 (en) * | 2003-07-29 | 2003-09-03 | Astrazeneca Ab | Pharmaceutical composition |
BRPI0510604B8 (pt) | 2004-05-06 | 2021-05-25 | Warner Lambert Co | composto 4-fenilamino-quinazolin-6-il-amida, seu uso e composição farmacêutica que o compreende composto 4-fenilamino-quinazolin-6-il-amida, seu uso e composição farmacêutica que o compreende |
RU2424805C2 (ru) | 2005-09-12 | 2011-07-27 | Актелион Фармасьютиклз Лтд | Стабильные фармацевтические композиции, включающие пиримидинсульфамид |
EP3954715A3 (en) | 2006-10-27 | 2022-05-04 | Capsugel Belgium NV | Hydroxypropyl methyl cellulose hard capsules and process of manufacture |
US10406105B2 (en) * | 2007-06-06 | 2019-09-10 | Basf Se | Pharmaceutical formulation for the production of rapidly disintegrating tablets |
MX2010001837A (es) | 2007-08-17 | 2010-03-10 | Actelion Pharmaceuticals Ltd | Derivados de 4-pirimidinasulfamida. |
US8728516B2 (en) * | 2009-04-30 | 2014-05-20 | Abbvie Inc. | Stabilized lipid formulation of apoptosis promoter |
TWI532484B (zh) * | 2009-06-08 | 2016-05-11 | 艾伯維有限公司 | 包含凋亡促進劑之固態分散劑 |
TWI540132B (zh) * | 2009-06-08 | 2016-07-01 | 亞培公司 | Bcl-2族群抑制劑之口服醫藥劑型 |
KR20120046216A (ko) * | 2009-07-02 | 2012-05-09 | 와이어쓰 엘엘씨 | 3-시아노퀴놀린 정제 제형 및 이의 용도 |
JP5779591B2 (ja) * | 2009-12-22 | 2015-09-16 | アッヴィ・インコーポレイテッド | Abt−263カプセル剤 |
JP4574742B1 (ja) * | 2010-04-08 | 2010-11-04 | 有限会社ミールジャパン | プロポリス組成物 |
US20120277210A1 (en) | 2010-10-29 | 2012-11-01 | Abbott Laboratories | Solid dispersions containing an apoptosis-inducing agent |
UA113500C2 (xx) | 2010-10-29 | 2017-02-10 | Одержані екструзією розплаву тверді дисперсії, що містять індукуючий апоптоз засіб | |
US20120129853A1 (en) | 2010-11-23 | 2012-05-24 | Abbott Laboratories | Methods of treatment using selective bcl-2 inhibitors |
SI2643322T1 (en) | 2010-11-23 | 2018-01-31 | Abbvie Inc. | Salts and crystalline forms of an apoptosis induction agent |
WO2012071340A1 (en) | 2010-11-23 | 2012-05-31 | Metamagnetics Inc. | Antenna module having reduced size, high gain, and increased power efficiency |
CN102631347B (zh) * | 2012-05-03 | 2014-06-25 | 石药集团中奇制药技术(石家庄)有限公司 | 一种吉非替尼药物组合物及其制备方法 |
US20140275082A1 (en) | 2013-03-14 | 2014-09-18 | Abbvie Inc. | Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases |
KR101332829B1 (ko) * | 2013-05-31 | 2013-11-27 | 재단법인 통합의료진흥원 | 보중익기탕을 포함하는 폐암 치료용 조성물 |
GB201400034D0 (en) | 2014-01-02 | 2014-02-19 | Astrazeneca Ab | Pharmaceutical Compositions comprising AZD9291 |
KR101721831B1 (ko) * | 2014-11-06 | 2017-03-31 | 주식회사 종근당 | 로베글리타존을 함유하는 경구 투여용 약제학적 조성물 |
US20180000827A1 (en) * | 2014-12-19 | 2018-01-04 | Synthon B.V. | Pharmaceutical composition comprising gefitinib |
FI4233847T3 (fi) * | 2015-02-26 | 2024-09-24 | Takeda Pharmaceuticals Co | Metoksiureajohdannaista ja mannitolihiukkasia käsittävä tabletti |
KR101739731B1 (ko) * | 2015-12-31 | 2017-05-25 | 환인제약 주식회사 | 유당불내성 환자에게 투여가 가능하며, 복용편의성이 향상된 게피티니브를 함유하는 약제학적 조성물 |
CN108096251B (zh) * | 2016-11-24 | 2021-11-16 | 江苏恒瑞医药股份有限公司 | 一种吉非替尼药物组合物及其制备方法 |
CN107007562B (zh) * | 2017-02-16 | 2020-10-27 | 南京优科制药有限公司 | 一种吉非替尼片剂及其制备方法 |
Family Cites Families (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3608063A (en) * | 1969-08-15 | 1971-09-21 | Gilbert S Banker | Molecular drug entrapment process and compositions |
US4178376A (en) * | 1977-01-21 | 1979-12-11 | Interx Research Corporation | Method for inducing rapid therapeutically effective antimalarial levels of certain selected conventional antimalarials |
US4344934A (en) * | 1978-11-20 | 1982-08-17 | American Home Products Corporation | Therapeutic compositions with enhanced bioavailability |
US4704284A (en) * | 1982-08-12 | 1987-11-03 | Pfizer Inc. | Long-acting matrix tablet formulations |
AU661533B2 (en) * | 1992-01-20 | 1995-07-27 | Astrazeneca Ab | Quinazoline derivatives |
GB9207988D0 (en) * | 1992-04-10 | 1992-05-27 | Smithkline Beecham Plc | Topical composition |
CA2164344C (en) * | 1993-08-30 | 2004-06-29 | Stanley Lech | Tablet coating based on a melt-spun mixture of a saccharide and a polymer |
US5559158A (en) * | 1993-10-01 | 1996-09-24 | Abbott Laboratories | Pharmaceutical composition |
GB9508538D0 (en) * | 1995-04-27 | 1995-06-14 | Zeneca Ltd | Quinazoline derivatives |
GB2306885B (en) * | 1995-11-08 | 1999-07-14 | Reckitt & Colmann Prod Ltd | Supersaturated Pharmaceutical Compositions |
NZ510991A (en) * | 1997-03-05 | 2002-11-26 | Sugen Inc | Use of formulations for hydrophobic pharmaceutical agents in treatment or prevention of cell proliferative disorders |
PT901786E (pt) * | 1997-08-11 | 2007-08-07 | Pfizer Prod Inc | Disperções farmacêuticas sólidas com biodisponibilidade melhorada |
UA74141C2 (uk) * | 1998-12-09 | 2005-11-15 | Дж.Д. Сірл Енд Ко. | Фармацевтична композиція на основі тонкоподрібненого еплеренону (варіанти), спосіб її одержання та спосіб лікування розладів, опосередкованих альдостероном (варіанти) |
US6248363B1 (en) * | 1999-11-23 | 2001-06-19 | Lipocine, Inc. | Solid carriers for improved delivery of active ingredients in pharmaceutical compositions |
US6294192B1 (en) * | 1999-02-26 | 2001-09-25 | Lipocine, Inc. | Triglyceride-free compositions and methods for improved delivery of hydrophobic therapeutic agents |
DE19911509A1 (de) * | 1999-03-15 | 2000-09-21 | Boehringer Ingelheim Pharma | Bicyclische Heterocyclen, diese Verbindungen enthaltende Arzneimittel, deren Verwendung und Verfahren zu ihrer Herstellung |
US6383471B1 (en) * | 1999-04-06 | 2002-05-07 | Lipocine, Inc. | Compositions and methods for improved delivery of ionizable hydrophobic therapeutic agents |
JP5767429B2 (ja) * | 1999-11-12 | 2015-08-19 | アッヴィ・インコーポレイテッド | 固体分散剤中の結晶化阻害剤 |
US6287599B1 (en) * | 2000-12-20 | 2001-09-11 | Shire Laboratories, Inc. | Sustained release pharmaceutical dosage forms with minimized pH dependent dissolution profiles |
KR100397792B1 (ko) * | 2001-06-28 | 2003-09-13 | 한국과학기술연구원 | 4-(페닐아미노)-[1,4]디옥사노[2,3-g]퀴나졸린 유도체 및그의 제조방법 |
DE60332322D1 (de) * | 2002-02-26 | 2010-06-10 | Astrazeneca Ab | Neue kristalline formen der krebsbekämpfenden verbindung zd1839 |
KR20050104152A (ko) | 2004-04-28 | 2005-11-02 | 최승호 | 경구용 약물의 흡수를 증진하는 약제학적 조성물 |
-
2003
- 2003-02-24 PL PL372215A patent/PL208114B1/pl unknown
- 2003-02-24 RU RU2004129280/15A patent/RU2318518C2/ru active
- 2003-02-24 WO PCT/GB2003/000803 patent/WO2003072139A1/en active IP Right Grant
- 2003-02-24 AU AU2003208444A patent/AU2003208444B2/en not_active Expired
- 2003-02-24 US US10/505,231 patent/US20050163835A1/en not_active Abandoned
- 2003-02-24 NZ NZ534513A patent/NZ534513A/en not_active IP Right Cessation
- 2003-02-24 BR BRPI0307786A patent/BRPI0307786B8/pt not_active IP Right Cessation
- 2003-02-24 MY MYPI20030631A patent/MY135609A/en unknown
- 2003-02-24 EP EP03706732A patent/EP1480679B1/en not_active Expired - Lifetime
- 2003-02-24 CN CNB038046164A patent/CN1326569C/zh not_active Expired - Lifetime
- 2003-02-24 KR KR1020107016079A patent/KR20100090726A/ko not_active Application Discontinuation
- 2003-02-24 ES ES03706732T patent/ES2286406T3/es not_active Expired - Lifetime
- 2003-02-24 UA UA20040907788A patent/UA76325C2/uk unknown
- 2003-02-24 DE DE60313956T patent/DE60313956T2/de not_active Expired - Lifetime
- 2003-02-24 CA CA2476587A patent/CA2476587C/en not_active Expired - Fee Related
- 2003-02-24 KR KR1020047013177A patent/KR101002374B1/ko active IP Right Grant
- 2003-02-24 AT AT03706732T patent/ATE362771T1/de active
- 2003-02-24 JP JP2003570883A patent/JP4544863B2/ja not_active Expired - Lifetime
- 2003-02-24 IL IL16364203A patent/IL163642A0/xx active IP Right Grant
- 2003-02-24 MX MXPA04008307A patent/MXPA04008307A/es active IP Right Grant
- 2003-02-24 PT PT03706732T patent/PT1480679E/pt unknown
- 2003-02-24 DK DK03706732T patent/DK1480679T3/da active
- 2003-02-25 TW TW092103905A patent/TWI271193B/zh not_active IP Right Cessation
- 2003-02-26 AR ARP030100636A patent/AR038848A1/es not_active Application Discontinuation
- 2003-02-26 UY UY27682A patent/UY27682A1/es not_active Application Discontinuation
- 2003-03-16 SA SA03240043A patent/SA03240043B1/ar unknown
-
2004
- 2004-08-19 IL IL163642A patent/IL163642A/en unknown
- 2004-08-24 CO CO04082661A patent/CO5601038A2/es not_active Application Discontinuation
- 2004-08-24 IS IS7420A patent/IS2462B/is unknown
- 2004-09-15 NO NO20043866A patent/NO328658B1/no not_active IP Right Cessation
-
2005
- 2005-04-20 HK HK05103383A patent/HK1070585A1/xx not_active IP Right Cessation
-
2007
- 2007-07-20 CY CY20071100974T patent/CY1108026T1/el unknown
-
2008
- 2008-09-19 US US12/234,321 patent/US20090186890A1/en not_active Abandoned
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
IL163642A0 (en) | Pharmaceutical formulation of iressa comprising a water-soluble cellulose derivative | |
TWI349664B (en) | Benzimidazole derivatives: preparation and pharmaceutical applications | |
AU2002350719A1 (en) | Pharmaceutical compositions comprising a basic respectively acidic drug compound, a surfactant and a physiologically tolerable water-soluble acid respectively base | |
IL221199A (en) | A fragrance-containing drug | |
IL163831A (en) | Derivatives of aminoindazoles, pharmaceutical compositions comprising them, process for their preparation and use thereof | |
IL161623A (en) | Nicotin-or isonicotin benzothiazole derivatives, their preparation and pharmaceutical compositions comprising them | |
AU2003901813A0 (en) | Pharmaceutical derivatives | |
TWI319317B (en) | Modified release pharmaceutical formulation | |
AU2002364468A1 (en) | Solid orally-dispersible pharmaceutical formulation | |
AU2003276572A1 (en) | Pharmaceutical dosage forms of biguanide-sulfonylurea combinations | |
IL165069A0 (en) | Immediate release pharmaceutical formulation | |
SI1673349T1 (sl) | Derivati benzimidazola: priprava in farmacevtske uporabe | |
IL166098A0 (en) | 3-guanindinocarbonyl-1-heteroaryl-indole derivatives preparation process their use as medicaments and pharmaceutical compositions comprising them | |
AU2003260239A1 (en) | Solid dosage forms for rapid dissolution of poorly soluble drugs | |
AU2002346457A1 (en) | Pharmaceutical formulations comprising indolinone derivatives | |
PL374761A1 (pl) | Pochodne N-benzodioksolilo, N-benzodioksanylo i N-benzodioksepinylo arylokarboksyamidu oraz kompozycje farmaceutyczne, zawierające takie pochodne | |
AU2003245033A1 (en) | An improved and stable pharmaceutical composition containing substituted benzimidazoles and a process for its preparation | |
AU2003280387A1 (en) | Pharmaceutical formulation comprising azithrocycin monohydrate | |
SI1480679T1 (sl) | Farmacevtska formulacija Iressa, ki obsega vodotopen celulozni derivat | |
AU2002333896A1 (en) | Solid pharmaceutical formulation for a piperazine urea derivative | |
HK1068277A1 (en) | Pharmaceutical compositions comprising chelidonineor derivatives thereof | |
IL174081A0 (en) | Formulation for obtaining a pharmaceutical composition, methods of obtaining and use thereof | |
AU2003215543A1 (en) | Water- soluble derivatives of lipophilic drugs | |
AU2003242538A1 (en) | Use of 2-oxo-1-pyrrolidone derivatives for the preparation of a drug | |
HRP20040757A2 (en) | A stable pharmaceutical formulation comprising torsemide modification ii |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FF | Patent granted | ||
KB | Patent renewed | ||
KB | Patent renewed |