IL134212A0 - Use of mhc class ii ligands as adjuvant for vaccination and of lag-3 in cancer treatment - Google Patents

Use of mhc class ii ligands as adjuvant for vaccination and of lag-3 in cancer treatment

Info

Publication number: IL134212A0
Authority: IL; Israel
Prior art keywords: mhc class; lag; adjuvant; vaccination; ligands
Prior art date: 1997-07-25

Application number

IL13421298A

Other languages

English (en)

Original Assignee

Roussy Inst Gustave

Applied Research Systems

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-07-25

Filing date

1998-07-23

Publication date

2001-04-30

1998-07-23 Application filed by Roussy Inst Gustave, Applied Research Systems filed Critical Roussy Inst Gustave

2001-04-30 Publication of IL134212A0 publication Critical patent/IL134212A0/xx

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
- A61K38/1774—Immunoglobulin superfamily (e.g. CD2, CD4, CD8, ICAM molecules, B7 molecules, Fc-receptors, MHC-molecules)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55516—Proteins; Peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Immunology (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Epidemiology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Microbiology (AREA)
Mycology (AREA)
Oncology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Communicable Diseases (AREA)
Tropical Medicine & Parasitology (AREA)
Cell Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Zoology (AREA)
Gastroenterology & Hepatology (AREA)
Virology (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

IL13421298A 1997-07-25 1998-07-23 Use of mhc class ii ligands as adjuvant for vaccination and of lag-3 in cancer treatment IL134212A0 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP97401800A EP0893507A1 (en)	1997-07-25	1997-07-25	Use of MHC class II ligands (CD4 and LAG-3) as adjuvant for vaccination and of LAG-3 in cancer treatment
PCT/EP1998/004621 WO1999004810A2 (en)	1997-07-25	1998-07-23	Use of mhc class ii ligands as adjuvant for vaccination and of lag-3 in cancer treatment

Publications (1)

Publication Number	Publication Date
IL134212A0 true IL134212A0 (en)	2001-04-30

Family

ID=8229825

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
IL13421298A IL134212A0 (en)	1997-07-25	1998-07-23	Use of mhc class ii ligands as adjuvant for vaccination and of lag-3 in cancer treatment
IL134212A IL134212A (en)	1997-07-25	2000-01-24	The use of MHC ACLASS II ligands as a vaccine supplement and in LAG-3 in the treatment of cancer

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
IL134212A IL134212A (en)	1997-07-25	2000-01-24	The use of MHC ACLASS II ligands as a vaccine supplement and in LAG-3 in the treatment of cancer

Country Status (20)

Country	Link
US (2)	US6410509B1 (xx)
EP (3)	EP0893507A1 (xx)
JP (1)	JP4723722B2 (xx)
KR (1)	KR100603075B1 (xx)
CN (1)	CN1184320C (xx)
AT (2)	ATE324455T1 (xx)
AU (1)	AU753738B2 (xx)
BR (1)	BR9811037A (xx)
CA (2)	CA2732570C (xx)
DE (2)	DE69834330T2 (xx)
DK (1)	DK1002108T3 (xx)
EA (3)	EA005405B1 (xx)
EE (1)	EE200000039A (xx)
ES (1)	ES2262242T3 (xx)
HK (1)	HK1030014A1 (xx)
IL (2)	IL134212A0 (xx)
NO (1)	NO20000378D0 (xx)
PT (1)	PT1002108E (xx)
UA (1)	UA75322C2 (xx)
WO (1)	WO1999004810A2 (xx)

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ATE519779T1 (de) *	2001-09-19	2011-08-15	Roussy Inst Gustave	An das glu-pro motiv-bindende proteine und peptide, diese enthaltende therapeutische zusammensetzungen und deren anwendungen
EP1596871A4 (en)	2003-02-28	2006-08-23	Drew M Pardoll	T-CELL REGULATION
KR20050082389A (ko) *	2004-02-18	2005-08-23	메덱스젠 주식회사	직렬 연쇄체를 갖는 면역접합체를 포함하는 장기이식합병증 치료용 약제학적 조성물
FR2868781B1 (fr) *	2004-04-13	2008-02-22	Immutep	Composition de vaccin comprenant un ligand cmh de classe ii couple a un antigene, procede de preparation et utilisations
EP1777523A1 (en) *	2005-10-19	2007-04-25	INSERM (Institut National de la Santé et de la Recherche Médicale)	An in vitro method for the prognosis of progression of a cancer and of the outcome in a patient and means for performing said method
EP2044949A1 (en) *	2007-10-05	2009-04-08	Immutep	Use of recombinant lag-3 or the derivatives thereof for eliciting monocyte immune response
WO2011031139A1 (en)	2009-09-09	2011-03-17	Universiteit Utrecht Holding B.V.	An ataq protein or a part thereof as a vaccine
SA110310855B1 (ar)	2009-11-13	2014-09-16	Laboratories Leti S L Unipersonal	استخدام مصدر l3 و/ أو l5 كلقاح أو كوسيلة تشخيصية لمرض طفيلي
PL2638062T3 (pl)	2010-11-10	2018-11-30	Laboratorios Leti, S.L.	Nowy adiuwant
GB201322626D0 (en)	2013-12-19	2014-02-05	Immutep S A	Combined preparations for the treatment of cancer
JOP20200094A1 (ar)	2014-01-24	2017-06-16	Dana Farber Cancer Inst Inc	جزيئات جسم مضاد لـ pd-1 واستخداماتها
CN103751778B (zh) *	2014-01-28	2016-09-28	复旦大学	3′-脱氧腺苷在制备广谱疫苗增效的免疫佐剂中的应用
ME03558B (me)	2014-03-14	2020-07-20	Novartis Ag	Molekuli anti-lag-3 antiтela i njihove upotrebe
AU2015329070B2 (en)	2014-10-07	2018-11-22	Nec Corporation	Hsp70-derived peptide, pharmaceutical composition for treating or preventing cancer using same, immunity inducer, and method for producing antigen-presenting cell
US9827308B2 (en)	2014-12-10	2017-11-28	Wisconsin Alumni Research Foundation	Mini-intronic plasmid DNA vaccines in combination with LAG3 blockade
GB201500374D0 (en)	2015-01-09	2015-02-25	Immutep S A	Combined preparations for the treatment of cancer
TW202115102A (zh)	2015-03-09	2021-04-16	日商賽多利克公司	來自gpc3之胜肽、使用此胜肽之用於治療或預防癌症之醫藥組成物、免疫誘導劑、及抗原呈現細胞之製造方法
TWI738646B (zh)	2015-04-07	2021-09-11	日商賽多利克公司	醫藥組成物
JP6925980B2 (ja)	2015-05-13	2021-08-25	アジェナスインコーポレイテッド	がんの処置および予防のためのワクチン
IL274572B2 (en)	2015-07-16	2024-01-01	Biolinerx Ltd	Compositions and methods for treating cancer
US10265379B2 (en)	2015-09-16	2019-04-23	Annabelle Rodriguez Oquendo	Use of recombinant lymphocyte activation gene-3 as a companion therapeutic for patients at risk for cardiovascular disease and other chronic inflammatory diseases
WO2017046409A1 (en)	2015-09-18	2017-03-23	Rijksuniversiteit Groningen	Long chain inulin for stimulating an immune response
BR112019006075A2 (pt)	2016-10-11	2019-06-18	Cytlimic Inc	medicamento
CN108204958A (zh) *	2016-12-19	2018-06-26	伊缪泰普有限公司	结合测定
JP2021522239A (ja)	2018-04-26	2021-08-30	アジェナスインコーポレイテッド	熱ショックタンパク質結合ペプチド組成物およびその使用方法
CA3114585A1 (en) *	2018-09-27	2020-04-02	Genocea Biosciences, Inc.	Treatment methods
JP2020138940A (ja)	2019-02-28	2020-09-03	テルモ株式会社	治療方法

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JPH03505039A (ja) *	1988-08-22	1991-11-07	アメリカ合衆国	可溶性ｃｄ４を発現するレトロウイルスベクター、エイズの遺伝子治療法
JPH02231083A (ja) *	1988-08-31	1990-09-13	Eisai Co Ltd	組換ナチュラルキラー細胞活性化因子
IL93599A0 (en) *	1989-03-03	1990-12-23	Microgenesys Inc	Kit and/or composition for the prevention or treatment of aids
EP0394827A1 (en) *	1989-04-26	1990-10-31	F. Hoffmann-La Roche Ag	Chimaeric CD4-immunoglobulin polypeptides
FR2656800B1 (fr) *	1990-01-08	1992-05-15	Roussy Inst Gustave	Nouvelles proteines produits par les lymphocytes humains, sequence d'adn codant pour ces proteines et applications pharmaceutiques et biologiques.
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1997
- 1997-07-25 EP EP97401800A patent/EP0893507A1/en not_active Withdrawn
1998
- 1998-07-23 BR BR9811037-3A patent/BR9811037A/pt not_active IP Right Cessation
- 1998-07-23 DE DE69834330T patent/DE69834330T2/de not_active Expired - Lifetime
- 1998-07-23 WO PCT/EP1998/004621 patent/WO1999004810A2/en active IP Right Grant
- 1998-07-23 AU AU92547/98A patent/AU753738B2/en not_active Expired
- 1998-07-23 EE EEP200000039A patent/EE200000039A/xx unknown
- 1998-07-23 CN CNB988075474A patent/CN1184320C/zh not_active Expired - Lifetime
- 1998-07-23 EA EA200200565A patent/EA005405B1/ru not_active IP Right Cessation
- 1998-07-23 JP JP2000503862A patent/JP4723722B2/ja not_active Expired - Lifetime
- 1998-07-23 ES ES98945090T patent/ES2262242T3/es not_active Expired - Lifetime
- 1998-07-23 EP EP06008545A patent/EP1698701B1/en not_active Expired - Lifetime
- 1998-07-23 CA CA2732570A patent/CA2732570C/en not_active Expired - Lifetime
- 1998-07-23 DE DE69841866T patent/DE69841866D1/de not_active Expired - Lifetime
- 1998-07-23 DK DK98945090T patent/DK1002108T3/da active
- 1998-07-23 UA UA2000020976A patent/UA75322C2/uk unknown
- 1998-07-23 CA CA2293805A patent/CA2293805C/en not_active Expired - Lifetime
- 1998-07-23 EA EA200000161A patent/EA003740B1/ru not_active IP Right Cessation
- 1998-07-23 EP EP98945090A patent/EP1002108B1/en not_active Expired - Lifetime
- 1998-07-23 IL IL13421298A patent/IL134212A0/xx unknown
- 1998-07-23 AT AT98945090T patent/ATE324455T1/de active
- 1998-07-23 AT AT06008545T patent/ATE478956T1/de not_active IP Right Cessation
- 1998-07-23 KR KR1020007000265A patent/KR100603075B1/ko not_active IP Right Cessation
- 1998-07-23 EA EA200300092A patent/EA200300092A1/ru unknown
- 1998-07-23 PT PT98945090T patent/PT1002108E/pt unknown
2000
- 2000-01-24 IL IL134212A patent/IL134212A/en not_active IP Right Cessation
- 2000-01-25 NO NO20000378A patent/NO20000378D0/no not_active Application Discontinuation
- 2000-01-27 US US09/492,113 patent/US6410509B1/en not_active Expired - Lifetime
2001
- 2001-01-30 HK HK01100662A patent/HK1030014A1/xx not_active IP Right Cessation
2002
- 2002-01-10 US US10/041,600 patent/US7109026B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
US7109026B2 (en)	2006-09-19
WO1999004810A3 (en)	1999-07-08
EP1698701B1 (en)	2010-08-25
ATE324455T1 (de)	2006-05-15
AU753738B2 (en)	2002-10-24
DE69841866D1 (de)	2010-10-07
CA2732570C (en)	2014-11-18
NO20000378L (no)	2000-01-25
EA200200565A1 (ru)	2002-10-31
CN1184320C (zh)	2005-01-12
EA003740B1 (ru)	2003-08-28
KR100603075B1 (ko)	2006-07-20
BR9811037A (pt)	2000-08-01
US6410509B1 (en)	2002-06-25
EP1002108A2 (en)	2000-05-24
DK1002108T3 (da)	2006-08-21
WO1999004810A2 (en)	1999-02-04
KR20010021706A (ko)	2001-03-15
HK1030014A1 (en)	2001-04-20
EE200000039A (et)	2000-10-16
NO20000378D0 (no)	2000-01-25
US20020192195A1 (en)	2002-12-19
JP4723722B2 (ja)	2011-07-13
DE69834330D1 (de)	2006-06-01
EA005405B1 (ru)	2005-02-24
PT1002108E (pt)	2006-09-29
AU9254798A (en)	1999-02-16
DE69834330T2 (de)	2007-03-29
EA200000161A1 (ru)	2000-10-30
EP0893507A1 (en)	1999-01-27
EP1698701A1 (en)	2006-09-06
EA200300092A1 (ru)	2003-06-26
CA2293805A1 (en)	1999-02-04
CA2732570A1 (en)	1999-02-04
ATE478956T1 (de)	2010-09-15
CA2293805C (en)	2011-05-03
IL134212A (en)	2012-03-29
EP1002108B1 (en)	2006-04-26
JP2001510806A (ja)	2001-08-07
CN1265149A (zh)	2000-08-30
UA75322C2 (en)	2006-04-17
ES2262242T3 (es)	2006-11-16

Publication	Publication Date	Title
IL134212A0 (en)	2001-04-30	Use of mhc class ii ligands as adjuvant for vaccination and of lag-3 in cancer treatment
ATE106013T1 (de)	1994-06-15	Arzneimittelfreisetzungssystem aus glucan und adjuvant.
DK0490077T3 (da)	1998-01-26	Antisense-oligonukleotider til behandling af cancer
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ID21529A (id)	1999-06-24	Metode dan komposisi untuk pengobatan dan pencegahan tumor, gangguan yang berhubungan dengan tumor dan kakeksia
IL134345A0 (en)	2001-04-30	Methods for treatment of patients afflicted with multiple sclerosis using consensus interferon
IL112969A0 (en)	1995-06-29	Pharmaceutical composition comprising t-cell actiVator for the treatment of cancer
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WO1998035045A3 (en)	1998-10-29	Leishmania antigens for use in the therapy and diagnosis of leishmaniasis
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WO1997033620A3 (de)	1998-02-05	Verbindungen zur behandlung von tumoren
BR0212446A (pt)	2004-08-17	Uso de 4-piridilmetilftalazinas para tratamento de câncer
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