IL129871A - Process for preparing 4-phenyl-substituted octanoyl-oxazolidin-2-one intermediates that are useful for preparing pyran-2-ones useful for treating retroviral infections - Google Patents

Process for preparing 4-phenyl-substituted octanoyl-oxazolidin-2-one intermediates that are useful for preparing pyran-2-ones useful for treating retroviral infections

Info

Publication number: IL129871A
Authority: IL; Israel
Prior art keywords: preparing; useful; ones; pyran; oxazolidin
Prior art date: 1994-05-06

Application number

IL12987195A

Other languages

English (en)

Original Assignee

Pharmacia & Upjohn Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-05-06

Filing date

1995-05-01

Publication date

2003-11-23

1995-05-01 Application filed by Pharmacia & Upjohn Inc filed Critical Pharmacia & Upjohn Inc

2003-11-23 Publication of IL129871A publication Critical patent/IL129871A/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/32—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/34—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D309/36—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms
- C07D309/38—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms one oxygen atom in position 2 or 4, e.g. pyrones
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/74—Benzo[b]pyrans, hydrogenated in the carbocyclic ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Virology (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Molecular Biology (AREA)
AIDS & HIV (AREA)
Tropical Medicine & Parasitology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Pyrane Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

IL12987195A 1994-05-06 1995-05-01 Process for preparing 4-phenyl-substituted octanoyl-oxazolidin-2-one intermediates that are useful for preparing pyran-2-ones useful for treating retroviral infections IL129871A (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US23881794A	1994-05-06	1994-05-06
US34936194A	1994-12-02	1994-12-02

Publications (1)

Publication Number	Publication Date
IL129871A true IL129871A (en)	2003-11-23

Family

ID=26931995

Family Applications (3)

Application Number	Title	Priority Date	Filing Date
IL12987195A IL129871A (en)	1994-05-06	1995-05-01	Process for preparing 4-phenyl-substituted octanoyl-oxazolidin-2-one intermediates that are useful for preparing pyran-2-ones useful for treating retroviral infections
IL11356796A IL113567A (en)	1994-05-06	1996-05-01	Pyran-2-one and 5,6-dihydropyran-2-one derivatives useful in treating retroviral infections
IL12987199A IL129871A0 (en)	1994-05-06	1999-05-10	A process for the preparation of compounds for treating retroviral infections

Family Applications After (2)

Application Number	Title	Priority Date	Filing Date
IL11356796A IL113567A (en)	1994-05-06	1996-05-01	Pyran-2-one and 5,6-dihydropyran-2-one derivatives useful in treating retroviral infections
IL12987199A IL129871A0 (en)	1994-05-06	1999-05-10	A process for the preparation of compounds for treating retroviral infections

Country Status (32)

Country	Link
US (2)	US5852195A (ko)
EP (1)	EP0758327B1 (ko)
JP (1)	JP3883206B2 (ko)
KR (1)	KR100445929B1 (ko)
CN (2)	CN1329378C (ko)
AT (1)	ATE236894T1 (ko)
AU (2)	AU701965B2 (ko)
BR (1)	BR9507615A (ko)
CA (2)	CA2187523C (ko)
CO (1)	CO4810313A1 (ko)
CZ (1)	CZ296515B6 (ko)
DE (2)	DE122006000014I2 (ko)
DK (1)	DK0758327T3 (ko)
ES (1)	ES2192201T3 (ko)
FI (1)	FI117387B (ko)
FR (1)	FR05C0047I2 (ko)
HU (1)	HU228057B1 (ko)
IL (3)	IL129871A (ko)
LU (1)	LU91220I2 (ko)
MX (1)	MX9605391A (ko)
MY (2)	MY149862A (ko)
NL (1)	NL300216I2 (ko)
NO (2)	NO315799B1 (ko)
NZ (1)	NZ285510A (ko)
PE (1)	PE23196A1 (ko)
PL (1)	PL190540B1 (ko)
PT (1)	PT758327E (ko)
RU (1)	RU2139284C1 (ko)
SI (1)	SI0758327T1 (ko)
SK (1)	SK284407B6 (ko)
TW (1)	TW504507B (ko)
WO (1)	WO1995030670A2 (ko)

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1995
- 1995-05-01 IL IL12987195A patent/IL129871A/xx not_active IP Right Cessation
- 1995-05-04 CN CNB2004100346805A patent/CN1329378C/zh not_active Expired - Lifetime
- 1995-05-04 MX MX9605391A patent/MX9605391A/es active IP Right Grant
- 1995-05-04 AU AU24626/95A patent/AU701965B2/en not_active Expired
- 1995-05-04 AT AT95918864T patent/ATE236894T1/de active
- 1995-05-04 SI SI9530660T patent/SI0758327T1/xx unknown
- 1995-05-04 JP JP52901695A patent/JP3883206B2/ja not_active Expired - Lifetime
- 1995-05-04 PT PT95918864T patent/PT758327E/pt unknown
- 1995-05-04 ES ES95918864T patent/ES2192201T3/es not_active Expired - Lifetime
- 1995-05-04 DK DK95918864T patent/DK0758327T3/da active
- 1995-05-04 NZ NZ285510A patent/NZ285510A/en not_active IP Right Cessation
- 1995-05-04 CZ CZ0317296A patent/CZ296515B6/cs not_active IP Right Cessation
- 1995-05-04 CN CNB951935534A patent/CN1154642C/zh not_active Expired - Lifetime
- 1995-05-04 HU HU9603074A patent/HU228057B1/hu active Protection Beyond IP Right Term
- 1995-05-04 EP EP95918864A patent/EP0758327B1/en not_active Expired - Lifetime
- 1995-05-04 US US08/809,224 patent/US5852195A/en not_active Expired - Lifetime
- 1995-05-04 DE DE1995630294 patent/DE122006000014I2/de active Active
- 1995-05-04 BR BR9507615A patent/BR9507615A/pt active Search and Examination
- 1995-05-04 TW TW084104473A patent/TW504507B/zh not_active IP Right Cessation
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- 1995-05-04 WO PCT/US1995/005219 patent/WO1995030670A2/en active IP Right Grant
- 1995-05-04 DE DE69530294T patent/DE69530294T2/de not_active Expired - Lifetime
- 1995-05-04 CA CA002560489A patent/CA2560489C/en not_active Expired - Lifetime
- 1995-05-04 KR KR1019960706245A patent/KR100445929B1/ko not_active Expired - Lifetime
- 1995-05-04 RU RU96123286A patent/RU2139284C1/ru active
- 1995-05-05 CO CO95018810A patent/CO4810313A1/es unknown
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- 1995-05-08 PE PE1995268036A patent/PE23196A1/es not_active IP Right Cessation
1996
- 1996-05-01 IL IL11356796A patent/IL113567A/xx not_active IP Right Cessation
- 1996-11-05 FI FI964441A patent/FI117387B/fi not_active IP Right Cessation
- 1996-11-05 NO NO19964676A patent/NO315799B1/no not_active IP Right Cessation
1998
- 1998-11-09 US US09/188,998 patent/US6169181B1/en not_active Expired - Lifetime
1999
- 1999-04-09 AU AU23686/99A patent/AU718117B2/en not_active Expired
- 1999-05-10 IL IL12987199A patent/IL129871A0/xx unknown
2005
- 2005-12-22 FR FR05C0047C patent/FR05C0047I2/fr active Active
2006
- 2006-01-20 NL NL300216C patent/NL300216I2/nl unknown
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Also Published As

Publication number	Publication date
FI117387B (fi)	2006-09-29
HK1084667A1 (en)	2006-08-04
DE122006000014I2 (de)	2007-03-29
RU2139284C1 (ru)	1999-10-10
HU9603074D0 (en)	1997-01-28
KR970702858A (ko)	1997-06-10
CA2187523A1 (en)	1995-11-16
WO1995030670A2 (en)	1995-11-16
US6169181B1 (en)	2001-01-02
CA2560489A1 (en)	1995-11-16
CZ317296A3 (en)	1997-04-16
AU2368699A (en)	1999-06-03
PT758327E (pt)	2003-08-29
WO1995030670A3 (en)	1996-04-25
HU228057B1 (en)	2012-09-28
HUT77601A (hu)	1998-06-29
NO2006003I2 (no)	2008-10-20
JP3883206B2 (ja)	2007-02-21
IL113567A (en)	2003-05-29
PE23196A1 (es)	1996-06-07
MY149862A (en)	2013-10-31
AU2462695A (en)	1995-11-29
PL190540B1 (pl)	2005-12-30
HK1066796A1 (zh)	2005-04-01
ES2192201T3 (es)	2003-10-01
EP0758327B1 (en)	2003-04-09
SI0758327T1 (en)	2003-08-31
JPH09512821A (ja)	1997-12-22
SK138496A3 (en)	1997-06-04
FI964441A0 (fi)	1996-11-05
PL317061A1 (en)	1997-03-03
SK284407B6 (sk)	2005-03-04
NL300216I2 (nl)	2006-06-01
CA2560489C (en)	2010-01-12
KR100445929B1 (ko)	2005-09-30
NO964676L (no)	1997-01-06
CN1150424A (zh)	1997-05-21
CN1539825A (zh)	2004-10-27
NO964676D0 (no)	1996-11-05
NO315799B1 (no)	2003-10-27
MX9605391A (es)	1997-12-31
TW504507B (en)	2002-10-01
FR05C0047I1 (ko)	2006-03-10
MY127701A (en)	2006-12-29
FR05C0047I2 (ko)	2007-10-19
DK0758327T3 (da)	2003-07-28
IL129871A0 (en)	2000-02-29
DE69530294D1 (de)	2003-05-15
CZ296515B6 (cs)	2006-04-12
DE69530294T2 (de)	2003-12-24
NL300216I1 (nl)	2006-04-03
US5852195A (en)	1998-12-22
CN1329378C (zh)	2007-08-01
CN1154642C (zh)	2004-06-23
CO4810313A1 (es)	1999-06-30
NZ285510A (en)	1998-03-25
AU718117B2 (en)	2000-04-06
LU91220I2 (fr)	2006-04-10
CA2187523C (en)	2006-11-21
DE122006000014I1 (de)	2006-11-16
FI964441L (fi)	1996-11-05
NO2006003I1 (no)	2006-03-13
EP0758327A1 (en)	1997-02-19
BR9507615A (pt)	1997-09-09
ATE236894T1 (de)	2003-04-15
AU701965B2 (en)	1999-02-11

Publication	Publication Date	Title
IL129871A (en)	2003-11-23	Process for preparing 4-phenyl-substituted octanoyl-oxazolidin-2-one intermediates that are useful for preparing pyran-2-ones useful for treating retroviral infections
NO953070D0 (no)	1995-08-04	4-hydroksy-benzopyran-2-oner og 4-hydroksysykloalkyl[BÅpyran-2-oner anvendbare for behandling av retrovirusinfeksjoner
MY119031A (en)	2005-03-31	Pyran-2-ones and 5,6-dihydropyran-2-ones useful for treating hiv and other retroviruses
TR200800474T2 (tr)	2008-04-21	Florfenikole aracı maddelerin hazırlanmasına ilişkin işlem.
DE69321845D1 (en)	1998-12-03	Hydroxyethylaminosulfonamide verwendbar als inhibitoren retroviraler proteasen
AU9125191A (en)	1992-06-11	Retroviral protease inhibitors
MX9803672A (es)	1998-09-30	Nuevos derivados de fenilamidina, procedimiento para su preparacion y su utilizacion como medicamentos.
ZA200005110B (en)	2001-05-22	Process for preparing intermediates.
EP0381114A3 (en)	1991-11-13	Exo-3',4'-0-benzylidene-3"-demethylchartreusin and its salts
DE69816095D1 (de)	2003-08-07	Herstellung von beta-mehtylcarbapenem-zwischenprodukten

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2009-11-18	KB	Patent renewed
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2016-01-31	EXP	Patent expired