IL101655A - The use of R) + (- 3-amino-1-hydroxy-pyrrolidin-2-one for the treatment of anxiety - Google Patents
The use of R) + (- 3-amino-1-hydroxy-pyrrolidin-2-one for the treatment of anxietyInfo
- Publication number
- IL101655A IL101655A IL10165592A IL10165592A IL101655A IL 101655 A IL101655 A IL 101655A IL 10165592 A IL10165592 A IL 10165592A IL 10165592 A IL10165592 A IL 10165592A IL 101655 A IL101655 A IL 101655A
- Authority
- IL
- Israel
- Prior art keywords
- rats
- veh
- amino
- test
- hydroxy
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Anesthesiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/688,232 US5145866A (en) | 1991-04-22 | 1991-04-22 | Method of treating anxiety with the aid of r(+)-3-amino-1-hydroxy-pyrrolidin-2-one |
Publications (2)
Publication Number | Publication Date |
---|---|
IL101655A0 IL101655A0 (en) | 1992-12-30 |
IL101655A true IL101655A (en) | 1998-07-15 |
Family
ID=24763636
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL10165592A IL101655A (en) | 1991-04-22 | 1992-04-20 | The use of R) + (- 3-amino-1-hydroxy-pyrrolidin-2-one for the treatment of anxiety |
Country Status (9)
Country | Link |
---|---|
US (1) | US5145866A (hu) |
EP (1) | EP0510489A1 (hu) |
JP (1) | JP2580429B2 (hu) |
KR (1) | KR100210180B1 (hu) |
AU (1) | AU647707B2 (hu) |
CA (1) | CA2066468A1 (hu) |
HU (1) | HU217076B (hu) |
IE (1) | IE921237A1 (hu) |
IL (1) | IL101655A (hu) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1251987A (zh) * | 1997-03-11 | 2000-05-03 | 达尔文发现有限公司 | 含有r-和s-对映体分离部分的剂型 |
US6391922B1 (en) | 1998-01-13 | 2002-05-21 | Synchroneuron, Llc | Treatment of posttraumatic stress disorder, obsessive-compulsive disorder and related neuropsychiatric disorders |
US6982361B1 (en) * | 2000-02-25 | 2006-01-03 | The Regents Of The University Of California | Method of screening a compound for anxiolytic activity in an Apolipoprotein e knockout animal |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3167476A (en) * | 1965-01-26 | preparations acting on the central nervous | ||
GB8727792D0 (en) * | 1987-11-27 | 1987-12-31 | Merck Sharp & Dohme | Therapeutic agents |
-
1991
- 1991-04-22 US US07/688,232 patent/US5145866A/en not_active Expired - Fee Related
-
1992
- 1992-04-14 EP EP92106417A patent/EP0510489A1/en not_active Ceased
- 1992-04-16 IE IE123792A patent/IE921237A1/en not_active Application Discontinuation
- 1992-04-16 AU AU15000/92A patent/AU647707B2/en not_active Ceased
- 1992-04-20 IL IL10165592A patent/IL101655A/en not_active IP Right Cessation
- 1992-04-21 JP JP4100051A patent/JP2580429B2/ja not_active Expired - Lifetime
- 1992-04-21 CA CA002066468A patent/CA2066468A1/en not_active Abandoned
- 1992-04-21 KR KR1019920006641A patent/KR100210180B1/ko not_active IP Right Cessation
- 1992-04-22 HU HU9201306A patent/HU217076B/hu not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
IL101655A0 (en) | 1992-12-30 |
EP0510489A1 (en) | 1992-10-28 |
US5145866A (en) | 1992-09-08 |
IE921237A1 (en) | 1992-11-04 |
KR100210180B1 (ko) | 1999-07-15 |
CA2066468A1 (en) | 1992-10-23 |
AU1500092A (en) | 1992-10-29 |
HU9201306D0 (en) | 1992-07-28 |
JP2580429B2 (ja) | 1997-02-12 |
KR920019349A (ko) | 1992-11-19 |
AU647707B2 (en) | 1994-03-24 |
HUT62789A (en) | 1993-06-28 |
HU217076B (hu) | 1999-11-29 |
JPH05112451A (ja) | 1993-05-07 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FF | Patent granted | ||
KB | Patent renewed | ||
MM9K | Patent not in force due to non-payment of renewal fees |