HUP0400261A3 - Stereoselective reduction of substituted acetophenone - Google Patents

Stereoselective reduction of substituted acetophenone

Info

Publication number: HUP0400261A3
Authority: HU; Hungary
Prior art keywords: stereoselective reduction; substituted acetophenone; acetophenone; substituted; stereoselective
Prior art date: 2001-03-22

Application number

HU0400261A

Other languages

English (en)

Original Assignee

Bristol Myers Squibb Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-03-22

Filing date

2002-03-06

Publication date

2005-11-28

2002-03-06 Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co

2004-09-28 Publication of HUP0400261A2 publication Critical patent/HUP0400261A2/hu

2005-11-28 Publication of HUP0400261A3 publication Critical patent/HUP0400261A3/hu

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
- C12P7/22—Preparation of oxygen-containing organic compounds containing a hydroxy group aromatic
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/911—Microorganisms using fungi
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/911—Microorganisms using fungi
- Y10S435/938—Pichia

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Zoology (AREA)
Life Sciences & Earth Sciences (AREA)
Wood Science & Technology (AREA)
Chemical Kinetics & Catalysis (AREA)
Microbiology (AREA)
General Chemical & Material Sciences (AREA)
Biotechnology (AREA)
Health & Medical Sciences (AREA)
Biochemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
General Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Analytical Chemistry (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Enzymes And Modification Thereof (AREA)

HU0400261A 2001-03-22 2002-03-06 Stereoselective reduction of substituted acetophenone HUP0400261A3 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US27802501P	2001-03-22	2001-03-22
PCT/US2002/006783 WO2002077258A1 (en)	2001-03-22	2002-03-06	Stereoselective reduction of substituted acetophenone

Publications (2)

Publication Number	Publication Date
HUP0400261A2 HUP0400261A2 (hu)	2004-09-28
HUP0400261A3 true HUP0400261A3 (en)	2005-11-28

Family

ID=23063377

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
HU0400261A HUP0400261A3 (en)	2001-03-22	2002-03-06	Stereoselective reduction of substituted acetophenone

Country Status (13)

Country	Link
US (1)	US6800477B2 (hu)
EP (1)	EP1370677A1 (hu)
JP (1)	JP2004532017A (hu)
KR (1)	KR20030085012A (hu)
CN (1)	CN1498273A (hu)
BR (1)	BR0208265A (hu)
CA (1)	CA2441267A1 (hu)
CZ (1)	CZ20032496A3 (hu)
HU (1)	HUP0400261A3 (hu)
IL (1)	IL157386A0 (hu)
MX (1)	MXPA03008437A (hu)
PL (1)	PL364577A1 (hu)
WO (1)	WO2002077258A1 (hu)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP1453516A2 (de) *	2001-10-17	2004-09-08	Boehringer Ingelheim Pharma GmbH & Co.KG	5-substituierte 4-amino-2-phenylamino-pyrimdinderivate und ihre verwendung als beta-amyloid modulatoren
RU2007106863A (ru) *	2004-08-26	2008-08-27	Пфайзер Инк. (US)	Энантиоселективное биопреобразование для получения промежуточных соединений ингибитора белка тирозинкиназы
WO2007084625A2 (en) *	2006-01-19	2007-07-26	Mount Sinai School Of Medicine	Novel compounds and methods for inhibiting p53 activity
EP2066788B1 (en) *	2006-10-02	2014-07-23	Codexis, Inc.	Compositions and methods for producing stereoisomerically pure statins and synthetic intermediates therefor
JP2010517574A (ja) *	2007-02-08	2010-05-27	コデクシス，インコーポレイテッド	ケトレダクターゼおよびその使用
WO2009029554A2 (en)	2007-08-24	2009-03-05	Codexis, Inc.	Improved ketoreductase polypeptides for the stereoselective production of (r)-3-hydroxythiolane
CN101855342B (zh)	2007-09-13	2013-07-10	科德克希思公司	用于还原苯乙酮的酮还原酶多肽
CN101889081B (zh)	2007-09-28	2014-06-18	科德克希思公司	酮还原酶多肽及其用途
EP2205727B1 (en) *	2007-10-01	2015-06-24	Codexis, Inc.	Ketoreductase polypeptides for the production of azetidinone
EP2329013B1 (en) *	2008-08-27	2015-10-28	Codexis, Inc.	Ketoreductase polypeptides for the production of a 3-aryl-3-hydroxypropanamine from a 3-aryl-3-ketopropanamine
US8288131B2 (en) *	2008-08-27	2012-10-16	Codexis, Inc.	Ketoreductase polypeptides and uses thereof
US8288141B2 (en)	2008-08-27	2012-10-16	Codexis, Inc.	Ketoreductase polypeptides for the production of 3-aryl-3-hydroxypropanamine from a 3-aryl-3-ketopropanamine
WO2010025085A2 (en)	2008-08-29	2010-03-04	Codexis, Inc.	Ketoreductase polypeptides for the stereoselective production of (4s)-3[(5s)-5(4-fluorophenyl)-5-hydroxypentanoyl]-4-phenyl-1,3-oxazolidin-2-one
US8501436B2 (en) *	2009-06-22	2013-08-06	Sk Biopharmaceuticals Co. Ltd.	Method for preparation of carbamic acid (R)-1-aryl-2-tetrazolyl-ethyl ester
EP2446025B1 (en)	2009-06-22	2018-08-08	Codexis, Inc.	Ketoreductase-mediated stereoselective route to alpha chloroalcohols
EP2467473B1 (en)	2009-08-19	2016-03-23	Codexis, Inc.	Ketoreductase polypeptides for the preparation of phenylephrine
US8404461B2 (en)	2009-10-15	2013-03-26	SK Biopharmaceutical Co. Ltd.	Method for preparation of carbamic acid (R)-1-aryl-2-tetrazolyl-ethyl ester
US9080192B2 (en)	2010-02-10	2015-07-14	Codexis, Inc.	Processes using amino acid dehydrogenases and ketoreductase-based cofactor regenerating system
WO2011140219A1 (en)	2010-05-04	2011-11-10	Codexis, Inc.	Biocatalysts for ezetimibe synthesis
CN103228658A (zh) *	2010-10-08	2013-07-31	卡迪拉保健有限公司	用于通过酶促转化制备西他列汀的中间体的方法
US9139819B2 (en)	2011-11-18	2015-09-22	Codexis, Inc.	Biocatalysts for the preparation of hydroxy substituted carbamates
DE102012017026A1 (de)	2012-08-28	2014-03-06	Forschungszentrum Jülich GmbH	Sensor für NADP(H) und Entwicklung von Alkoholdehydrogenasen
WO2016130412A1 (en)	2015-02-10	2016-08-18	Codexis, Inc.	Ketoreductase polypeptides for the synthesis of chiral compounds
US11021729B2 (en)	2017-04-27	2021-06-01	Codexis, Inc.	Ketoreductase polypeptides and polynucleotides
CN107686447A (zh) *	2017-08-25	2018-02-13	许昌恒生制药有限公司	一种替格瑞洛中间体的制备方法
EP3587393B1 (en)	2018-06-21	2024-01-17	F.I.S.- Fabbrica Italiana Sintetici S.p.A.	Enzymatic process for the preparation of droxidopa
CN117098762A (zh)	2021-04-02	2023-11-21	基因泰克公司	用于制备双环酮化合物的方法
WO2024150146A1 (en)	2023-01-12	2024-07-18	Novartis Ag	Engineered ketoreductase polypeptides

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0538693A3 (en) *	1991-10-23	1994-08-17	Squibb & Sons Inc	Stereoselective preparation of halophenyl alcohols
DE59306681D1 (de)	1992-03-13	1997-07-10	Forschungszentrum Juelich Gmbh	Neue ketoester-reduktase, deren herstellung und verwendung für enzymatische redoxreaktionen
CA2103932A1 (en)	1992-11-05	1994-05-06	Ramesh N. Patel	Stereoselective reduction of ketones
WO1999023242A1 (en) *	1997-11-04	1999-05-14	Eli Lilly And Company	Ketoreductase gene and protein from yeast

2002
- 2002-03-06 CN CNA028068858A patent/CN1498273A/zh active Pending
- 2002-03-06 CA CA002441267A patent/CA2441267A1/en not_active Abandoned
- 2002-03-06 PL PL02364577A patent/PL364577A1/xx not_active Application Discontinuation
- 2002-03-06 WO PCT/US2002/006783 patent/WO2002077258A1/en not_active Application Discontinuation
- 2002-03-06 MX MXPA03008437A patent/MXPA03008437A/es unknown
- 2002-03-06 JP JP2002576699A patent/JP2004532017A/ja active Pending
- 2002-03-06 EP EP02728418A patent/EP1370677A1/en not_active Withdrawn
- 2002-03-06 IL IL15738602A patent/IL157386A0/xx unknown
- 2002-03-06 CZ CZ20032496A patent/CZ20032496A3/cs unknown
- 2002-03-06 BR BR0208265-9A patent/BR0208265A/pt not_active IP Right Cessation
- 2002-03-06 KR KR10-2003-7012198A patent/KR20030085012A/ko not_active Application Discontinuation
- 2002-03-06 US US10/092,263 patent/US6800477B2/en not_active Expired - Lifetime
- 2002-03-06 HU HU0400261A patent/HUP0400261A3/hu unknown

Also Published As

Publication number	Publication date
BR0208265A (pt)	2004-03-02
KR20030085012A (ko)	2003-11-01
MXPA03008437A (es)	2004-01-29
CZ20032496A3 (cs)	2003-12-17
IL157386A0 (en)	2004-02-19
WO2002077258A1 (en)	2002-10-03
EP1370677A1 (en)	2003-12-17
PL364577A1 (en)	2004-12-13
CA2441267A1 (en)	2002-10-03
JP2004532017A (ja)	2004-10-21
US6800477B2 (en)	2004-10-05
CN1498273A (zh)	2004-05-19
HUP0400261A2 (hu)	2004-09-28
US20030068811A1 (en)	2003-04-10

Publication	Publication Date	Title
HUP0400261A3 (en)	2005-11-28	Stereoselective reduction of substituted acetophenone
HUP0401017A3 (en)	2005-06-28	Combination of probiotics
EP1442061A4 (en)	2007-03-14	REDUCTION OF IMMUNOGENICITIES OF IMMUNOGLOBULINS BY FRAMEWORK PATCHING
PL355161A1 (en)	2003-01-13	Method of manufacture
GB2387597B (en)	2004-11-10	Stereoselective preparation of 3-hydroxy-3-phenylpropionitrile
EP1453913A4 (en)	2006-04-05	SUBSTITUTED ALKANES COMPOUNDS AND USES THEREOF
HUP0300873A3 (en)	2006-02-28	Stereoselective reduction of substituted oxo-butanes
HUP0500734A3 (en)	2005-12-28	Use of 2-alkoxyphenyl-substituted imidazotriazinones
IL160812A0 (en)	2004-08-31	Method of attachment
GB2374097B (en)	2006-02-22	Decoration of conservatories
IL161178A0 (en)	2004-08-31	MODIFICATIONS OF SOLID 3-sn-PHOSPHOGLYCERIDES
AU2002317734A1 (en)	2003-05-08	Denitrification of aquarium water
IL156839A0 (en)	2004-02-08	Use of chromanes
GB2413134B (en)	2006-01-04	Decoration of conservatories
AU2002360957A1 (en)	2003-07-09	Heterogenisation of catalytic components
HU0104370D0 (en)	2001-12-28	Honeyed schnaps of oerseg
TW573751U (en)	2004-01-21	Structure capable of preventing jaming
TW459973U (en)	2001-10-11	Improved structure of ventilator
TW510531U (en)	2002-11-11	New structure of micro-radiator
TW511737U (en)	2002-11-21	New structure of micro-radiator
TW510530U (en)	2002-11-11	New structure of micro-radiator
PL347080A1 (en)	2002-10-21	Method of reducing operational losses
HU2338U (en)	2002-07-29	Ventilated rack-system for experimental animal-boxes
TW494780U (en)	2002-07-11	Structure of swimmeret
TW501859U (en)	2002-09-01	Improvement of fixing-stand structure

Legal Events

Date	Code	Title	Description
2006-08-28	FA9A	Lapse of provisional patent protection due to relinquishment or protection considered relinquished