HUP0302693A3 - Phenylalanin-derivatives, integrin inhibitors of alpha4, their use and process for their preparation - Google Patents

Phenylalanin-derivatives, integrin inhibitors of alpha4, their use and process for their preparation

Info

Publication number: HUP0302693A3
Authority: HU; Hungary
Prior art keywords: phenylalanin; alpha4; derivatives; preparation; integrin inhibitors
Prior art date: 2000-08-31

Application number

HU0302693A

Other languages

English (en)

Original Assignee

Tanabe Seiyaku Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-08-31

Filing date

2001-08-27

Publication date

2005-05-30

2001-08-27 Application filed by Tanabe Seiyaku Co filed Critical Tanabe Seiyaku Co

2003-12-29 Publication of HUP0302693A2 publication Critical patent/HUP0302693A2/hu

2005-05-30 Publication of HUP0302693A3 publication Critical patent/HUP0302693A3/hu

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/64—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings
- C07C233/81—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
- C07C233/82—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
- C07C233/87—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom of a carbon skeleton containing six-membered aromatic rings
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- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
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Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Diabetes (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Biomedical Technology (AREA)
Immunology (AREA)
Hematology (AREA)
Physical Education & Sports Medicine (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Rheumatology (AREA)
Pulmonology (AREA)
Orthopedic Medicine & Surgery (AREA)
Urology & Nephrology (AREA)
Epidemiology (AREA)
Vascular Medicine (AREA)
Dermatology (AREA)
Psychiatry (AREA)
Obesity (AREA)
Virology (AREA)
Hospice & Palliative Care (AREA)
Emergency Medicine (AREA)
Pain & Pain Management (AREA)
Molecular Biology (AREA)
Endocrinology (AREA)
Oncology (AREA)

HU0302693A 2000-08-31 2001-08-27 Phenylalanin-derivatives, integrin inhibitors of alpha4, their use and process for their preparation HUP0302693A3 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US22912800P	2000-08-31	2000-08-31
PCT/US2001/026594 WO2002018320A2 (en)	2000-08-31	2001-08-27	INHIBITORS OF α4 MEDIATED CELL ADHESION

Publications (2)

Publication Number	Publication Date
HUP0302693A2 HUP0302693A2 (hu)	2003-12-29
HUP0302693A3 true HUP0302693A3 (en)	2005-05-30

Family

ID=22859926

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
HU0302693A HUP0302693A3 (en)	2000-08-31	2001-08-27	Phenylalanin-derivatives, integrin inhibitors of alpha4, their use and process for their preparation

Country Status (28)

Country	Link
US (6)	US7026501B2 (hu)
EP (1)	EP1315694B1 (hu)
JP (1)	JP3899022B2 (hu)
KR (1)	KR100528049B1 (hu)
CN (1)	CN1229334C (hu)
AR (1)	AR034556A1 (hu)
AT (1)	ATE292615T1 (hu)
AU (2)	AU2001286778B2 (hu)
BR (1)	BR0113629A (hu)
CA (1)	CA2418054C (hu)
CZ (1)	CZ303460B6 (hu)
DE (1)	DE60109943T2 (hu)
DK (1)	DK1315694T3 (hu)
ES (1)	ES2240509T3 (hu)
HK (1)	HK1052684B (hu)
HU (1)	HUP0302693A3 (hu)
IL (2)	IL154305A0 (hu)
MX (1)	MXPA03001837A (hu)
MY (1)	MY129000A (hu)
NO (1)	NO327861B1 (hu)
NZ (1)	NZ524043A (hu)
PL (1)	PL206656B1 (hu)
PT (1)	PT1315694E (hu)
RU (1)	RU2250895C2 (hu)
SI (1)	SI1315694T1 (hu)
TW (1)	TWI224587B (hu)
WO (1)	WO2002018320A2 (hu)
ZA (1)	ZA200301039B (hu)

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US7855291B2 (en)	2005-12-29	2010-12-21	Lexicon Pharmaceuticals, Inc.	Process for the preparation of substituted phenylalanines
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CN101379028A (zh) *	2006-02-09	2009-03-04	阿斯利康(瑞典)有限公司	化学化合物
CA2641160A1 (en) *	2006-02-28	2007-09-07	Elan Pharmaceuticals, Inc.	Methods of treating inflammatory and autoimmune diseases with alpha-4 inhibitory compounds
PL2676967T3 (pl) *	2006-02-28	2019-12-31	Biogen Ma Inc.	Metody leczenia chorób zapalnych i autoimmunologicznych za pomocą natalizumabu
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KR101601994B1 (ko)	2008-04-15	2016-03-17	에자이 알앤드디 매니지먼트 가부시키가이샤	3-페닐피라졸로[5,1-ｂ]티아졸 화합물
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2001
- 2001-08-21 MY MYPI20013917A patent/MY129000A/en unknown
- 2001-08-27 PT PT01966246T patent/PT1315694E/pt unknown
- 2001-08-27 HU HU0302693A patent/HUP0302693A3/hu unknown
- 2001-08-27 ZA ZA200301039A patent/ZA200301039B/xx unknown
- 2001-08-27 DK DK01966246T patent/DK1315694T3/da active
- 2001-08-27 RU RU2003105885/04A patent/RU2250895C2/ru not_active IP Right Cessation
- 2001-08-27 WO PCT/US2001/026594 patent/WO2002018320A2/en active IP Right Grant
- 2001-08-27 IL IL15430501A patent/IL154305A0/xx unknown
- 2001-08-27 SI SI200130351T patent/SI1315694T1/xx unknown
- 2001-08-27 CA CA 2418054 patent/CA2418054C/en not_active Expired - Fee Related
- 2001-08-27 JP JP2002523438A patent/JP3899022B2/ja not_active Expired - Fee Related
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- 2001-08-27 AU AU2001286778A patent/AU2001286778B2/en not_active Ceased
- 2001-08-27 DE DE60109943T patent/DE60109943T2/de not_active Expired - Lifetime
- 2001-08-27 CN CNB018149871A patent/CN1229334C/zh not_active Expired - Fee Related
- 2001-08-27 BR BR0113629-1A patent/BR0113629A/pt active Search and Examination
- 2001-08-27 KR KR10-2003-7001993A patent/KR100528049B1/ko not_active IP Right Cessation
- 2001-08-27 AU AU8677801A patent/AU8677801A/xx active Pending
- 2001-08-27 US US10/333,985 patent/US7026501B2/en not_active Expired - Fee Related
- 2001-08-27 PL PL365668A patent/PL206656B1/pl unknown
- 2001-08-27 MX MXPA03001837A patent/MXPA03001837A/es active IP Right Grant
- 2001-08-27 EP EP01966246A patent/EP1315694B1/en not_active Expired - Lifetime
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- 2001-08-27 ES ES01966246T patent/ES2240509T3/es not_active Expired - Lifetime
- 2001-08-31 TW TW090121581A patent/TWI224587B/zh not_active IP Right Cessation
- 2001-08-31 AR ARP010104172A patent/AR034556A1/es active IP Right Grant
2003
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- 2003-02-25 NO NO20030885A patent/NO327861B1/no not_active IP Right Cessation
- 2003-07-11 HK HK03105043.3A patent/HK1052684B/zh not_active IP Right Cessation
2005
- 2005-07-13 US US11/179,729 patent/US7456217B2/en not_active Expired - Fee Related
2008
- 2008-10-07 US US12/247,129 patent/US7671090B2/en not_active Expired - Fee Related
2010
- 2010-01-07 US US12/683,648 patent/US7872151B2/en not_active Expired - Fee Related
- 2010-12-08 US US12/962,707 patent/US8501809B2/en not_active Expired - Fee Related
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Also Published As

Publication number	Publication date
US7456217B2 (en)	2008-11-25
RU2250895C2 (ru)	2005-04-27
US7872151B2 (en)	2011-01-18
CA2418054A1 (en)	2002-03-07
MY129000A (en)	2007-03-30
HUP0302693A2 (hu)	2003-12-29
IL154305A0 (en)	2003-09-17
ATE292615T1 (de)	2005-04-15
KR100528049B1 (ko)	2005-11-15
DE60109943T2 (de)	2006-02-09
PL206656B1 (pl)	2010-09-30
AR034556A1 (es)	2004-03-03
CZ303460B6 (cs)	2012-09-26
HK1052684A1 (en)	2003-09-26
US7026501B2 (en)	2006-04-11
CZ2003487A3 (cs)	2003-06-18
AU2001286778B2 (en)	2005-02-10
PT1315694E (pt)	2005-07-29
CN1229334C (zh)	2005-11-30
US7671090B2 (en)	2010-03-02
ES2240509T3 (es)	2005-10-16
SI1315694T1 (en)	2005-10-31
US8501809B2 (en)	2013-08-06
US20050282900A1 (en)	2005-12-22
NO327861B1 (no)	2009-10-05
BR0113629A (pt)	2003-07-22
CA2418054C (en)	2008-08-05
IL154305A (en)	2010-11-30
NZ524043A (en)	2004-08-27
US20090111879A1 (en)	2009-04-30
US20030176498A1 (en)	2003-09-18
US20100113820A1 (en)	2010-05-06
KR20030059099A (ko)	2003-07-07
WO2002018320A3 (en)	2002-06-06
DK1315694T3 (da)	2005-08-08
TWI224587B (en)	2004-12-01
JP3899022B2 (ja)	2007-03-28
MXPA03001837A (es)	2003-10-15
WO2002018320A2 (en)	2002-03-07
AU8677801A (en)	2002-03-13
NO20030885D0 (no)	2003-02-25
JP2004507519A (ja)	2004-03-11
US20110077299A1 (en)	2011-03-31
EP1315694A2 (en)	2003-06-04
ZA200301039B (en)	2004-02-09
DE60109943D1 (de)	2005-05-12
PL365668A1 (en)	2005-01-10
EP1315694B1 (en)	2005-04-06
CN1449377A (zh)	2003-10-15
US20130289109A1 (en)	2013-10-31
HK1052684B (zh)	2005-07-22
NO20030885L (no)	2003-02-25

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Date	Code	Title	Description
2008-04-28	HC9A	Change of name, address	Owner name: MITSUBISHI TANABE PHARMA CORPORATION, JP Free format text: FORMER OWNER(S): TANABE SEIYAKU CO., LTD., JP
2016-02-29	FA9A	Lapse of provisional patent protection due to relinquishment or protection considered relinquished

Date

Code

Title

Description

2008-04-28

HC9A

Change of name, address

Owner name: MITSUBISHI TANABE PHARMA CORPORATION, JP

Free format text: FORMER OWNER(S): TANABE SEIYAKU CO., LTD., JP

2016-02-29

FA9A

Lapse of provisional patent protection due to relinquishment or protection considered relinquished