HUP0203593A2 - Amikomicin, eljárás előállítására és gyógyszerként történő alkalmazása - Google Patents
Amikomicin, eljárás előállítására és gyógyszerként történő alkalmazásaInfo
- Publication number
- HUP0203593A2 HUP0203593A2 HU0203593A HUP0203593A HUP0203593A2 HU P0203593 A2 HUP0203593 A2 HU P0203593A2 HU 0203593 A HU0203593 A HU 0203593A HU P0203593 A HUP0203593 A HU P0203593A HU P0203593 A2 HUP0203593 A2 HU P0203593A2
- Authority
- HU
- Hungary
- Prior art keywords
- production
- pharmaceutical
- compound
- amycomycin
- stereoisomeric
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- VNFAKMBHDHVYLZ-HSTNYJNZSA-N (3E,5Z)-1-methyl-5-(2-methylpropylidene)-3-[(2E,20E,24E)-1,5,7,11,13,17,19,26,27,29,31,35,37,41,43-pentadecahydroxy-2,10,12,18,20,22,24,32,40,42,44-undecamethyl-23-oxopentatetraconta-2,20,24-trienylidene]pyrrolidine-2,4-dione Chemical compound CC(C)\C=C1/N(C)C(=O)\C(=C(\O)/C(/C)=C/CC(O)CC(O)CCC(C)C(O)C(C)C(O)CCCC(O)C(C)C(O)C(\C)=C\C(C)C(=O)C(\C)=C\C(O)C(O)CC(O)CC(O)C(C)CCC(O)CC(O)CCC(C)C(O)C(C)C(O)C(C)C)C1=O VNFAKMBHDHVYLZ-HSTNYJNZSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- 150000002148 esters Chemical class 0.000 abstract 1
- 150000002170 ethers Chemical class 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/44—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having three double bonds between ring members or between ring members and non-ring members
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/10—Nitrogen as only ring hetero atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Pyrrole Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
A találmány tárgya (A) képletű vegyület, gyógyszerészetilegalkalmazható sói, észterei, éterei és egyéb nyilvánvaló kémiaiekvivalensei, valamennyi sztereoizomer és tautomer alakjukban. Atalálmány az új vegyület előállítására szolgáló eljárást és avegyületet tartalmazó gyógyszerészeti készítményt is magában foglalja. Ó
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP99124456A EP1106604A1 (en) | 1999-12-08 | 1999-12-08 | Amycomycin, a process for its production and its use as a pharmaceutical |
PCT/EP2000/011752 WO2001042210A1 (en) | 1999-12-08 | 2000-11-25 | Amycomycin, a process for its production and its use as a pharmaceutical |
Publications (3)
Publication Number | Publication Date |
---|---|
HUP0203593A2 true HUP0203593A2 (hu) | 2003-02-28 |
HUP0203593A3 HUP0203593A3 (en) | 2003-12-29 |
HU225194B1 HU225194B1 (en) | 2006-08-28 |
Family
ID=8239554
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU0203593A HU225194B1 (en) | 1999-12-08 | 2000-11-25 | Amycomycin, a process for its production and its use as a pharmaceutical |
Country Status (28)
Country | Link |
---|---|
US (1) | US6642391B2 (hu) |
EP (2) | EP1106604A1 (hu) |
JP (1) | JP4750993B2 (hu) |
KR (1) | KR100728514B1 (hu) |
CN (1) | CN1217929C (hu) |
AT (1) | ATE298744T1 (hu) |
AU (1) | AU781398B2 (hu) |
BR (1) | BR0016223A (hu) |
CA (1) | CA2393518C (hu) |
CZ (1) | CZ294370B6 (hu) |
DE (1) | DE60021109T2 (hu) |
DK (1) | DK1237866T3 (hu) |
EE (1) | EE05219B1 (hu) |
ES (1) | ES2243332T3 (hu) |
HK (1) | HK1048998A1 (hu) |
HR (1) | HRP20020497B1 (hu) |
HU (1) | HU225194B1 (hu) |
IL (2) | IL149904A0 (hu) |
ME (1) | ME00182B (hu) |
NO (1) | NO322565B1 (hu) |
PL (1) | PL201809B1 (hu) |
PT (1) | PT1237866E (hu) |
RS (1) | RS50288B (hu) |
RU (1) | RU2261916C2 (hu) |
SI (1) | SI1237866T1 (hu) |
SK (1) | SK286776B6 (hu) |
WO (1) | WO2001042210A1 (hu) |
ZA (1) | ZA200204420B (hu) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102417919B (zh) * | 2011-09-02 | 2017-05-24 | 山东鲁抗医药股份有限公司 | 一种发酵法生产高纯度替考拉宁的方法 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8700513D0 (en) * | 1987-01-09 | 1987-02-11 | Pfizer Ltd | Antibiotics produced by fermentation |
CA2016382A1 (en) * | 1989-05-12 | 1990-11-12 | Marvin M. Hoehn | A59770 antibiotics |
JPH05163289A (ja) * | 1991-08-27 | 1993-06-29 | Microbial Chem Res Found | 新規な免疫抑制物質、mi710−51f6物質およびその製造法 |
JPH05286990A (ja) * | 1992-04-08 | 1993-11-02 | Meiji Seika Kaisha Ltd | 新規マクロライド抗生物質および微生物変換を利用したマクロライド抗生物質の製造法 |
JP3107455B2 (ja) * | 1992-05-08 | 2000-11-06 | 財団法人微生物化学研究会 | 新規抗生物質mi481−42f4−a及びその製造方法 |
JPH05317068A (ja) * | 1992-05-14 | 1993-12-03 | Kaiyo Bio Technol Kenkyusho:Kk | 抗生物質マグネシジンの一成分の選択的製造法 |
JPH0733736A (ja) * | 1993-07-26 | 1995-02-03 | Microbial Chem Res Found | 新規抗生物質アジセマイシンbおよびその製造方法 |
JPH09157266A (ja) * | 1995-12-04 | 1997-06-17 | Microbial Chem Res Found | 新規抗生物質エポキシキノマイシンaおよびbとその製造法 |
EP0816539A1 (de) | 1996-07-05 | 1998-01-07 | Maschinenfabrik Rieter Ag | Verfahren und Vorrichtung zur Produktionssteuerung an einer Karde |
JPH1045738A (ja) * | 1996-07-29 | 1998-02-17 | Microbial Chem Res Found | 抗生物質エポキシキノマイシンcおよびdとその製造法ならびに抗リウマチ剤 |
JPH10114777A (ja) * | 1996-10-09 | 1998-05-06 | Microbial Chem Res Found | 抗生物質スピロキシマイシンとその製造法 |
-
1999
- 1999-12-08 EP EP99124456A patent/EP1106604A1/en not_active Withdrawn
-
2000
- 2000-11-25 CN CN008135207A patent/CN1217929C/zh not_active Expired - Fee Related
- 2000-11-25 ES ES00983165T patent/ES2243332T3/es not_active Expired - Lifetime
- 2000-11-25 AU AU20019/01A patent/AU781398B2/en not_active Ceased
- 2000-11-25 KR KR1020027007292A patent/KR100728514B1/ko not_active Expired - Fee Related
- 2000-11-25 EE EEP200200280A patent/EE05219B1/xx not_active IP Right Cessation
- 2000-11-25 DE DE60021109T patent/DE60021109T2/de not_active Expired - Lifetime
- 2000-11-25 PL PL355627A patent/PL201809B1/pl unknown
- 2000-11-25 IL IL14990400A patent/IL149904A0/xx active IP Right Grant
- 2000-11-25 HU HU0203593A patent/HU225194B1/hu not_active IP Right Cessation
- 2000-11-25 ME MEP-2008-285A patent/ME00182B/me unknown
- 2000-11-25 WO PCT/EP2000/011752 patent/WO2001042210A1/en active IP Right Grant
- 2000-11-25 CA CA002393518A patent/CA2393518C/en not_active Expired - Fee Related
- 2000-11-25 RU RU2002118116/13A patent/RU2261916C2/ru not_active IP Right Cessation
- 2000-11-25 AT AT00983165T patent/ATE298744T1/de active
- 2000-11-25 JP JP2001543511A patent/JP4750993B2/ja not_active Expired - Fee Related
- 2000-11-25 PT PT00983165T patent/PT1237866E/pt unknown
- 2000-11-25 DK DK00983165T patent/DK1237866T3/da active
- 2000-11-25 BR BR0016223-0A patent/BR0016223A/pt not_active Application Discontinuation
- 2000-11-25 SI SI200030729T patent/SI1237866T1/xx unknown
- 2000-11-25 CZ CZ20021891A patent/CZ294370B6/cs not_active IP Right Cessation
- 2000-11-25 SK SK787-2002A patent/SK286776B6/sk not_active IP Right Cessation
- 2000-11-25 EP EP00983165A patent/EP1237866B1/en not_active Expired - Lifetime
- 2000-11-25 RS YUP-131/02A patent/RS50288B/sr unknown
- 2000-12-07 US US09/730,844 patent/US6642391B2/en not_active Expired - Lifetime
-
2002
- 2002-05-29 IL IL149904A patent/IL149904A/en not_active IP Right Cessation
- 2002-06-03 ZA ZA200204420A patent/ZA200204420B/xx unknown
- 2002-06-05 NO NO20022654A patent/NO322565B1/no not_active IP Right Cessation
- 2002-06-06 HR HR20020497A patent/HRP20020497B1/xx not_active IP Right Cessation
-
2003
- 2003-02-18 HK HK03101176A patent/HK1048998A1/xx not_active IP Right Cessation
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
MY136643A (en) | Pyrimidine derivatives for inhibition of cell-proliferation | |
YU70901A (sh) | Derivati 1,4-benzotiazepin-1,1 dioksida zamenjeni radikalima šećera, postupak za njihovu proizvodnju, lekovi koji sadrže ova jedinjenja i njihova primena | |
IS2600B (is) | Ný tríasólpýrimídínefnasambönd | |
HUP0004024A2 (hu) | Azabenzimidazolvázas vegyületek, eljárás előállításukra és ezeket tartalmazó gyógyszerkészítmények | |
AP1614A (en) | New heterocyclic compounds, their preparation and their use as medicaments, in particular as anti-bacterial agents. | |
MXPA03010877A (es) | Derivados de 2-anilin-pirimida como inhibidores de cinasa dependientes de ciclina. | |
RS50140B (sr) | Postupak za dobijanje perkihinina i njegova upotreba | |
HUP0001560A2 (hu) | Stabil kristályos 5-metil-tetrahidrofolsav-sók | |
MY144659A (en) | 2-hydroxy-3-heteroarylindole derivatives as gsk3 inhibitors | |
HUP9701265A2 (hu) | Imidazolinszármazékok, eljárás előállításukra és ezeket tartalmazó gyógyszerkészítények | |
PL364598A1 (en) | Stable polymorph of flibanserin, technical process for its preparation and the use thereof for preparing medicaments | |
GB0109122D0 (en) | Novel compounds | |
GEP20074045B (en) | (4-phenyl) piperidin-3-yl-phenylcarboxylate derivatives and related compounds as beta-secretase inhibitors for the treatment of alzheimer's disease | |
YU94103A (sh) | Novi derivati sulfonske kiseline | |
HUP0200580A2 (hu) | Celecoxib polimorf kristályos formái, eljárás az előállításukra és ezeket tartalmazó gyógyszerkészítmények | |
HUP0102515A2 (hu) | Ciklopeptidek, eljárás előállításukra, hatóanyagként azokat tartalmazó gyógyszerkészítmények és alkalmazásuk | |
DE60327998D1 (de) | Pyrimidine verbindungen | |
MXPA02004441A (es) | Derivados de isoxazol como inhibidores de la fosfodiesterasa. | |
HUP0105308A2 (hu) | Eletriptán-hidrobromid-monohidrát, eljárás az előállítására és a vegyületet tartalmazó gyógyszerkészítmények | |
YU5893A (sh) | Sulfonilkarbamid i postupak za njegovo dobijanje | |
HUP0203593A2 (hu) | Amikomicin, eljárás előállítására és gyógyszerként történő alkalmazása | |
HUP0104213A2 (hu) | Vankoreszmicin, eljárás előállítására és gyógyszerként történő alkalmazása | |
ATE344237T1 (de) | Hydroxyacetamidobenzolsulfonamidderivate | |
RS20050954A (en) | Use of bycyclo/2.2.1/heptane derivatives for the preparation of neuroprotective pharmaceutical compositions | |
HUP0300191A2 (hu) | 2,6-Diamino-6-metil-heptánsav és származékai, eljárás ezek előállítására és alkalmazásuk |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
MM4A | Lapse of definitive patent protection due to non-payment of fees |