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HUP0104035A3 - Novel erythromycin derivatives, preparation method and use as medicines - Google Patents

Novel erythromycin derivatives, preparation method and use as medicines

Info

Publication number
HUP0104035A3
HUP0104035A3 HU0104035A HUP0104035A HUP0104035A3 HU P0104035 A3 HUP0104035 A3 HU P0104035A3 HU 0104035 A HU0104035 A HU 0104035A HU P0104035 A HUP0104035 A HU P0104035A HU P0104035 A3 HUP0104035 A3 HU P0104035A3
Authority
HU
Hungary
Prior art keywords
medicines
preparation
erythromycin derivatives
novel erythromycin
novel
Prior art date
Application number
HU0104035A
Other languages
English (en)
Original Assignee
Aventis Pharma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa
Publication of HUP0104035A2 publication Critical patent/HUP0104035A2/hu
Publication of HUP0104035A3 publication Critical patent/HUP0104035A3/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
HU0104035A 1998-11-10 1999-11-09 Novel erythromycin derivatives, preparation method and use as medicines HUP0104035A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9814145A FR2785612A1 (fr) 1998-11-10 1998-11-10 Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
PCT/FR1999/002718 WO2000027857A2 (fr) 1998-11-10 1999-11-09 Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments

Publications (2)

Publication Number Publication Date
HUP0104035A2 HUP0104035A2 (hu) 2002-02-28
HUP0104035A3 true HUP0104035A3 (en) 2003-12-29

Family

ID=9532584

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0104035A HUP0104035A3 (en) 1998-11-10 1999-11-09 Novel erythromycin derivatives, preparation method and use as medicines

Country Status (28)

Country Link
US (2) US6455505B2 (hu)
EP (1) EP1016669B1 (hu)
JP (1) JP4698783B2 (hu)
KR (1) KR100567695B1 (hu)
CN (2) CN100351238C (hu)
AR (1) AR025814A1 (hu)
AT (1) ATE232879T1 (hu)
AU (1) AU766138B2 (hu)
BR (1) BR9915236A (hu)
CA (1) CA2350651C (hu)
CZ (1) CZ20011622A3 (hu)
DE (1) DE69905447T2 (hu)
DK (1) DK1016669T3 (hu)
EA (1) EA200100533A1 (hu)
ES (1) ES2189365T3 (hu)
FR (1) FR2785612A1 (hu)
HR (1) HRP20010335B1 (hu)
HU (1) HUP0104035A3 (hu)
IL (2) IL142996A0 (hu)
NO (1) NO20012272L (hu)
NZ (1) NZ511609A (hu)
PL (1) PL348098A1 (hu)
PT (1) PT1016669E (hu)
SI (1) SI20640A (hu)
TR (1) TR200101286T2 (hu)
TW (1) TWI237027B (hu)
WO (1) WO2000027857A2 (hu)
ZA (1) ZA200103801B (hu)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1147121E (pt) 1999-01-27 2004-04-30 Pfizer Prod Inc Antibioticos cetolidos
EE200100613A (et) 1999-05-24 2003-02-17 Pfizer Products Inc. 13-metüülerütromütsiini derivaadid
EP1167376B1 (en) 2000-06-30 2004-07-14 Pfizer Products Inc. Macrolide antibiotics
JP2004017020A (ja) * 2002-06-20 2004-01-22 Sony Corp コーティング方法および被コーティング粒子
ES2552682T3 (es) 2003-03-10 2015-12-01 Merck Sharp & Dohme Corp. Agentes antibacterianos novedosos
JP2008508322A (ja) * 2004-07-28 2008-03-21 ランバクシー ラボラトリーズ リミテッド 抗菌剤としてのケトライド誘導体
US20090170790A1 (en) * 2004-10-25 2009-07-02 Biswajit Das Ketolide derivatives as antibacterial agents
EP2214484A4 (en) 2007-10-25 2013-01-02 Cempra Pharmaceuticals Inc PROCESS FOR PREPARING ANTIBACTERIAL MAKROLIDE AGENTS
EP2358379B1 (en) * 2008-10-24 2015-12-16 Cempra Pharmaceuticals, Inc. Biodefenses using triazole-containing macrolides
US9937194B1 (en) 2009-06-12 2018-04-10 Cempra Pharmaceuticals, Inc. Compounds and methods for treating inflammatory diseases
US9480679B2 (en) 2009-09-10 2016-11-01 Cempra Pharmaceuticals, Inc. Methods for treating malaria, tuberculosis and MAC diseases
MX361413B (es) 2010-03-22 2018-12-05 Cempra Pharmaceuticals Inc Star Formas cristalinas de un macrólido y usos para las mismas.
AU2011255464C1 (en) 2010-05-20 2017-02-23 Cempra Pharmaceuticals, Inc. Processes for preparing macrolides and ketolides and intermediates therefor
KR20180110181A (ko) 2010-09-10 2018-10-08 셈프라 파마슈티컬스, 인크. 질환을 치료하기 위한 수소결합 형성 플루오로 케토라이드
EP2830632A4 (en) 2012-03-27 2015-10-21 Cempra Pharmaceuticals Inc PARENTERAL FORMULATIONS FOR THE ADMINISTRATION OF MACROLIDE ANTIBIOTICS
JP6426696B2 (ja) 2013-03-14 2018-11-21 センプラ ファーマシューティカルズ，インコーポレイテッド 呼吸器疾患の治療のための方法および製剤
BR112015023670A2 (pt) 2013-03-15 2017-07-18 Cempra Pharmaceuticals Inc processo para preparar um composto
JP6437523B2 (ja) 2013-04-04 2018-12-12 プレジデント アンド フェローズ オブ ハーバード カレッジ マクロライドならびにそれらの調製および使用の方法
EP3211997A4 (en) 2014-10-08 2018-10-24 President and Fellows of Harvard College 14-membered ketolides and methods of their preparation and use
CA2980315A1 (en) 2015-03-25 2016-09-29 President And Fellows Of Harvard College Macrolides with modified desosamine sugars and uses thereof
EP3190122A1 (en) * 2016-01-08 2017-07-12 LEK Pharmaceuticals d.d. A novel synthetic pathway towards solithromycin and purification thereof
CN106432383A (zh) * 2016-09-14 2017-02-22 重庆两江药物研发中心有限公司 索利霉素及其中间体的制备方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5671074A (en) * 1979-11-12 1981-06-13 Takeda Chem Ind Ltd 1,2-disubstituted-4-halogenoimidazole-5-acetic acid derivative
FR2669337B1 (fr) * 1990-11-21 1995-03-24 Roussel Uclaf Nouveaux derives descladinosyles de l'erythromycine, leur procede de preparation et leur application comme medicaments.
IL99995A (en) * 1990-11-21 1997-11-20 Roussel Uclaf Erythromycin derivatives, their preparation and pharmaceutical compositions containing them
US5527780A (en) * 1992-11-05 1996-06-18 Roussel Uclaf Erythromycin derivatives
FR2697524B1 (fr) * 1992-11-05 1994-12-23 Roussel Uclaf Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.
FR2719587B1 (fr) * 1994-05-03 1996-07-12 Roussel Uclaf Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.
FR2727969B1 (fr) * 1994-12-09 1997-01-17 Roussel Uclaf Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
FR2742757B1 (fr) * 1995-12-22 1998-01-30 Roussel Uclaf Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
EP1291350B1 (en) * 1996-09-04 2005-05-25 Abbott Laboratories 6-0 substituted ketolides having antibacterial activity
WO1998040392A1 (fr) * 1997-03-10 1998-09-17 Taisho Pharmaceutical Co., Ltd. Derives d'erythromycine a

Also Published As

Publication number Publication date
JP2000143689A (ja) 2000-05-26
NO20012272L (no) 2001-07-10
AR025814A1 (es) 2002-12-18
TR200101286T2 (tr) 2001-09-21
EP1016669A1 (fr) 2000-07-05
SI20640A (sl) 2002-02-28
EA200100533A1 (ru) 2001-10-22
JP4698783B2 (ja) 2011-06-08
ES2189365T3 (es) 2003-07-01
IL142996A0 (en) 2002-04-21
US20020013281A1 (en) 2002-01-31
DK1016669T3 (da) 2003-05-26
FR2785612A1 (fr) 2000-05-12
HRP20010335A2 (en) 2002-06-30
DE69905447D1 (de) 2003-03-27
EP1016669B1 (fr) 2003-02-19
TWI237027B (en) 2005-08-01
CA2350651C (fr) 2010-07-20
DE69905447T2 (de) 2003-07-24
ZA200103801B (en) 2002-05-10
PL348098A1 (en) 2002-05-06
AU1052600A (en) 2000-05-29
HRP20010335B1 (en) 2003-08-31
CN100351238C (zh) 2007-11-28
AU766138B2 (en) 2003-10-09
BR9915236A (pt) 2002-01-08
US6407257B1 (en) 2002-06-18
HUP0104035A2 (hu) 2002-02-28
PT1016669E (pt) 2003-07-31
US6455505B2 (en) 2002-09-24
CZ20011622A3 (cs) 2001-09-12
NO20012272D0 (no) 2001-05-09
WO2000027857A2 (fr) 2000-05-18
ATE232879T1 (de) 2003-03-15
US20020028781A1 (en) 2002-03-07
CN1240708C (zh) 2006-02-08
IL142996A (en) 2006-12-10
WO2000027857A3 (fr) 2000-08-17
KR20010080970A (ko) 2001-08-25
CA2350651A1 (fr) 2000-05-18
CN1333782A (zh) 2002-01-30
CN1814592A (zh) 2006-08-09
NZ511609A (en) 2003-07-25
KR100567695B1 (ko) 2006-04-05

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