CZ20011622A3 - Nové deriváty erythromycinu, způsob jejich přípravy a jejich použití jako léčiv - Google Patents

Nové deriváty erythromycinu, způsob jejich přípravy a jejich použití jako léčiv

Info

Publication number: CZ20011622A3
Authority: CZ; Czechia
Prior art keywords: medicaments; preparation; erythromycin derivatives; novel erythromycin; novel
Prior art date: 1998-11-10

Application number

CZ20011622A

Other languages

English (en)

Inventor

Constantin Agouridas

Alexis Denis

Claude Fromentin

Original Assignee

Aventis Pharma S. A.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-11-10

Filing date

1999-11-09

Publication date

2001-09-12

1999-11-09 Application filed by Aventis Pharma S. A. filed Critical Aventis Pharma S. A.

2001-09-12 Publication of CZ20011622A3 publication Critical patent/CZ20011622A3/cs

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H1/00—Processes for the preparation of sugar derivatives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Molecular Biology (AREA)
Engineering & Computer Science (AREA)
Biochemistry (AREA)
Genetics & Genomics (AREA)
Biotechnology (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Oncology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Communicable Diseases (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)

CZ20011622A 1998-11-10 1999-11-09 Nové deriváty erythromycinu, způsob jejich přípravy a jejich použití jako léčiv CZ20011622A3 (cs)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR9814145A FR2785612A1 (fr)	1998-11-10	1998-11-10	Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments

Publications (1)

Publication Number	Publication Date
CZ20011622A3 true CZ20011622A3 (cs)	2001-09-12

Family

ID=9532584

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CZ20011622A CZ20011622A3 (cs)	1998-11-10	1999-11-09	Nové deriváty erythromycinu, způsob jejich přípravy a jejich použití jako léčiv

Country Status (28)

Country	Link
US (2)	US6455505B2 (cs)
EP (1)	EP1016669B1 (cs)
JP (1)	JP4698783B2 (cs)
KR (1)	KR100567695B1 (cs)
CN (2)	CN100351238C (cs)
AR (1)	AR025814A1 (cs)
AT (1)	ATE232879T1 (cs)
AU (1)	AU766138B2 (cs)
BR (1)	BR9915236A (cs)
CA (1)	CA2350651C (cs)
CZ (1)	CZ20011622A3 (cs)
DE (1)	DE69905447T2 (cs)
DK (1)	DK1016669T3 (cs)
EA (1)	EA200100533A1 (cs)
ES (1)	ES2189365T3 (cs)
FR (1)	FR2785612A1 (cs)
HR (1)	HRP20010335B1 (cs)
HU (1)	HUP0104035A3 (cs)
IL (2)	IL142996A0 (cs)
NO (1)	NO20012272L (cs)
NZ (1)	NZ511609A (cs)
PL (1)	PL348098A1 (cs)
PT (1)	PT1016669E (cs)
SI (1)	SI20640A (cs)
TR (1)	TR200101286T2 (cs)
TW (1)	TWI237027B (cs)
WO (1)	WO2000027857A2 (cs)
ZA (1)	ZA200103801B (cs)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
OA11753A (en) *	1999-01-27	2005-07-19	Pfizer Prod Inc	Ketolide antibiotics.
OA11945A (en)	1999-05-24	2006-04-13	Pfizer Prod Inc	13-Methyl erythromycin derivatives.
ATE271062T1 (de)	2000-06-30	2004-07-15	Pfizer Prod Inc	Makrolid-antibiotika
JP2004017020A (ja) *	2002-06-20	2004-01-22	Sony Corp	コーティング方法および被コーティング粒子
EP2772254A3 (en)	2003-03-10	2015-03-11	Optimer Pharmaceuticals, Inc.	Novel Antibacterial Agents
EP1794171A2 (en) *	2004-07-28	2007-06-13	Ranbaxy Laboratories, Ltd.	Ketolide derivatives as antibacterial agents
WO2006046112A2 (en) *	2004-10-25	2006-05-04	Ranbaxy Laboratories Limited	Ketolide derivatives as antibacterial agents
CN105732745A (zh) *	2007-10-25	2016-07-06	森普拉制药公司	大环内酯类抗菌剂的制备方法
JP5711135B2 (ja)	2008-10-24	2015-04-30	センプラファーマシューティカルズ，インコーポレイテッド	胃腸疾患を治療するための方法
US9937194B1 (en)	2009-06-12	2018-04-10	Cempra Pharmaceuticals, Inc.	Compounds and methods for treating inflammatory diseases
ES2608285T3 (es)	2009-09-10	2017-04-07	Cempra Pharmaceuticals, Inc.	Procedimientos para el tratamiento de paludismo, tuberculosis y enfermedades por MAC
MY162411A (en)	2010-03-22	2017-06-15	Cempra Pharmaceuticals Inc	Crystalline forms of a macrolide, and uses therefor
SI2571506T1 (sl)	2010-05-20	2017-12-29	Cempra Pharmaceuticals, Inc.	Postopki za pripravo makrolidov in ketolidov ter njihovih intermediatov
WO2012034058A1 (en)	2010-09-10	2012-03-15	Cempra Pharmaceuticals, Inc.	Hydrogen bond forming fluoro ketolides for treating diseases
IN2014DN08939A (cs)	2012-03-27	2015-05-22	Cempra Pharmaceuticals Inc
CA2905975A1 (en)	2013-03-14	2014-09-25	Cempra Pharmaceuticals, Inc.	Methods for treating respiratory diseases and formulations therefor
KR20160020403A (ko)	2013-03-15	2016-02-23	셈프라 파마슈티컬스, 인크.	매크로라이드 항세균제들을 제조하기 위한 수렴 프로세스들
JP6437523B2 (ja)	2013-04-04	2018-12-12	プレジデントアンドフェローズオブハーバードカレッジ	マクロライドならびにそれらの調製および使用の方法
CN106998685A (zh)	2014-10-08	2017-08-01	哈佛大学的校长及成员们	14‑元酮内酯及其制备和使用方法
JP2018509452A (ja)	2015-03-25	2018-04-05	プレジデントアンドフェローズオブハーバードカレッジ	修飾デソサミン糖をもつマクロライドおよびその使用
EP3190122A1 (en) *	2016-01-08	2017-07-12	LEK Pharmaceuticals d.d.	A novel synthetic pathway towards solithromycin and purification thereof
CN106432383A (zh) *	2016-09-14	2017-02-22	重庆两江药物研发中心有限公司	索利霉素及其中间体的制备方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS5671074A (en) *	1979-11-12	1981-06-13	Takeda Chem Ind Ltd	1,2-disubstituted-4-halogenoimidazole-5-acetic acid derivative
FR2669337B1 (fr) *	1990-11-21	1995-03-24	Roussel Uclaf	Nouveaux derives descladinosyles de l'erythromycine, leur procede de preparation et leur application comme medicaments.
IL99995A (en) *	1990-11-21	1997-11-20	Roussel Uclaf	Erythromycin derivatives, their preparation and pharmaceutical compositions containing them
FR2697524B1 (fr) *	1992-11-05	1994-12-23	Roussel Uclaf	Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.
US5527780A (en) *	1992-11-05	1996-06-18	Roussel Uclaf	Erythromycin derivatives
FR2719587B1 (fr) *	1994-05-03	1996-07-12	Roussel Uclaf	Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.
FR2727969B1 (fr) *	1994-12-09	1997-01-17	Roussel Uclaf	Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
FR2742757B1 (fr) *	1995-12-22	1998-01-30	Roussel Uclaf	Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
JP4597274B2 (ja) *	1996-09-04	2010-12-15	アボット・ラボラトリーズ	抗菌活性を有する６―ｏ―置換ケトリド
AU4472897A (en) *	1997-03-10	1998-09-29	Taisho Pharmaceutical Co., Ltd.	Erythromycin a derivatives

1998
- 1998-11-10 FR FR9814145A patent/FR2785612A1/fr active Pending
1999
- 1999-11-03 US US09/433,146 patent/US6455505B2/en not_active Expired - Lifetime
- 1999-11-08 TW TW088119491A patent/TWI237027B/zh not_active IP Right Cessation
- 1999-11-09 AT AT99402783T patent/ATE232879T1/de active
- 1999-11-09 EP EP99402783A patent/EP1016669B1/fr not_active Expired - Lifetime
- 1999-11-09 DE DE69905447T patent/DE69905447T2/de not_active Expired - Lifetime
- 1999-11-09 HU HU0104035A patent/HUP0104035A3/hu unknown
- 1999-11-09 CA CA2350651A patent/CA2350651C/fr not_active Expired - Lifetime
- 1999-11-09 AU AU10526/00A patent/AU766138B2/en not_active Expired
- 1999-11-09 NZ NZ511609A patent/NZ511609A/en unknown
- 1999-11-09 SI SI9920091A patent/SI20640A/sl not_active IP Right Cessation
- 1999-11-09 WO PCT/FR1999/002718 patent/WO2000027857A2/fr active IP Right Grant
- 1999-11-09 BR BR9915236-3A patent/BR9915236A/pt active Search and Examination
- 1999-11-09 DK DK99402783T patent/DK1016669T3/da active
- 1999-11-09 TR TR2001/01286T patent/TR200101286T2/xx unknown
- 1999-11-09 CZ CZ20011622A patent/CZ20011622A3/cs unknown
- 1999-11-09 KR KR1020017005854A patent/KR100567695B1/ko active IP Right Grant
- 1999-11-09 PL PL99348098A patent/PL348098A1/xx not_active Application Discontinuation
- 1999-11-09 PT PT99402783T patent/PT1016669E/pt unknown
- 1999-11-09 ES ES99402783T patent/ES2189365T3/es not_active Expired - Lifetime
- 1999-11-09 EA EA200100533A patent/EA200100533A1/ru unknown
- 1999-11-09 JP JP31801599A patent/JP4698783B2/ja not_active Expired - Lifetime
- 1999-11-09 CN CNB200510128838XA patent/CN100351238C/zh not_active Expired - Lifetime
- 1999-11-09 CN CNB998154393A patent/CN1240708C/zh not_active Expired - Lifetime
- 1999-11-09 IL IL14299699A patent/IL142996A0/xx active IP Right Grant
- 1999-11-10 AR ARP990105702A patent/AR025814A1/es not_active Application Discontinuation
2000
- 2000-12-11 US US09/734,162 patent/US6407257B1/en not_active Expired - Lifetime
2001
- 2001-05-06 IL IL142996A patent/IL142996A/en not_active IP Right Cessation
- 2001-05-09 NO NO20012272A patent/NO20012272L/no not_active Application Discontinuation
- 2001-05-10 ZA ZA200103801A patent/ZA200103801B/en unknown
- 2001-05-10 HR HR990077A patent/HRP20010335B1/xx not_active IP Right Cessation

Also Published As

Publication number	Publication date
SI20640A (sl)	2002-02-28
ZA200103801B (en)	2002-05-10
US20020028781A1 (en)	2002-03-07
WO2000027857A3 (fr)	2000-08-17
WO2000027857A2 (fr)	2000-05-18
DK1016669T3 (da)	2003-05-26
CA2350651C (fr)	2010-07-20
FR2785612A1 (fr)	2000-05-12
PT1016669E (pt)	2003-07-31
HRP20010335B1 (en)	2003-08-31
HUP0104035A2 (hu)	2002-02-28
AR025814A1 (es)	2002-12-18
EP1016669B1 (fr)	2003-02-19
ES2189365T3 (es)	2003-07-01
US6407257B1 (en)	2002-06-18
CN1240708C (zh)	2006-02-08
CN100351238C (zh)	2007-11-28
PL348098A1 (en)	2002-05-06
NO20012272L (no)	2001-07-10
BR9915236A (pt)	2002-01-08
TWI237027B (en)	2005-08-01
CN1814592A (zh)	2006-08-09
EA200100533A1 (ru)	2001-10-22
CN1333782A (zh)	2002-01-30
IL142996A (en)	2006-12-10
JP2000143689A (ja)	2000-05-26
US20020013281A1 (en)	2002-01-31
HRP20010335A2 (en)	2002-06-30
ATE232879T1 (de)	2003-03-15
KR20010080970A (ko)	2001-08-25
US6455505B2 (en)	2002-09-24
KR100567695B1 (ko)	2006-04-05
EP1016669A1 (fr)	2000-07-05
DE69905447D1 (de)	2003-03-27
CA2350651A1 (fr)	2000-05-18
AU1052600A (en)	2000-05-29
NZ511609A (en)	2003-07-25
AU766138B2 (en)	2003-10-09
TR200101286T2 (tr)	2001-09-21
DE69905447T2 (de)	2003-07-24
HUP0104035A3 (en)	2003-12-29
NO20012272D0 (no)	2001-05-09
JP4698783B2 (ja)	2011-06-08
IL142996A0 (en)	2002-04-21

Publication	Publication Date	Title
SI0680967T1 (en)	1999-02-28	Erythromycin derivatives, their process of preparation and their use as medicaments
IL112954A0 (en)	1995-06-29	New erythromycin derivatives, their preparation process and their use as medicaments
CZ20011622A3 (cs)	2001-09-12	Nové deriváty erythromycinu, způsob jejich přípravy a jejich použití jako léčiv
HUP0000658A3 (en)	2001-03-28	Sulphonamide derivatives, process for their preparation, and their use as medicaments
HUP0105136A3 (en)	2002-05-28	Amide derivatives, process for their preparation and medicaments containing them
HUP0204245A3 (en)	2004-12-28	Novel n-azabicyclo-amide derivatives, process for their preparation, pharmaceutical compositions containing them and their use
HUP0201225A2 (en)	2002-08-28	4,5,6,7-tetrahydroindazole derivatives as antitumor agent and process for their preparation
PL344412A1 (en)	2001-11-05	Pyrazoline derivatives, their preparation and application as medicaments
HUP0300618A3 (en)	2003-12-29	Adamantana derivatives, process for their preparation, their use and pharmaceutical compositions containing them
ZA971659B (en)	1998-02-26	Erythromycin derivatives, their preparation process and their use as medicaments.
ZA997176B (en)	2000-11-20	Derivatives of erythromycin, their preparation process and their use as medicaments.
HUP9900958A3 (en)	2000-04-28	New derivatives of 2-fluoro-3-de[(2,6-dideoxy-3-c-methyl-3-0-methyl-alfa-l-ribohexopyranosyl)-oxy]-6-0-methyl-3-oxo-erytromycin, and their preparation process
LT2000004A (en)	2000-07-25	Derivatives of acyl-piperazinil-pyrimidins, preparation thereof and application as medicaments
HUP0100978A3 (en)	2003-08-28	Benzothiadiazoles and derivatives, process for their preparation and medicaments containing them
HUP0100927A3 (en)	2002-03-28	Antitumor substituted indene-derivatives, process for their preparation, medicaments containing them and their use
HUP0104620A3 (en)	2003-01-28	2-phenylpyran-4-one derivatives, process for their preparation and medicaments containing them
HUP0201315A3 (en)	2003-02-28	4-phenyl-pyrimidine derivatives, process for their preparation, their use and pharmaceutical compositions containing them
HUP0101234A3 (en)	2002-12-28	Betha-carboline derivatives, process for their preparation and pharmaceutical compositions thereof
AU3853597A (en)	1998-02-10	New derivatives of erythromycin, their preparation process and their use as medicaments
HUP0001245A3 (en)	2003-05-28	Novel erythromycin derivatives, method of preparation and application as medicines
HUP0201797A3 (en)	2003-03-28	3-amino-2-benzyl-1-phenyl-propane derivatives, process for their preparation, pharmaceutical compositions containing them and their use
AU5487798A (en)	1998-07-03	New derivatives of erythromycin, their preparation process and their use as medicaments
HUP0204572A3 (en)	2004-07-28	Substituierte bisindolylmaleinimide derivatives, process for their preparation and use and pharmaceutcial compositions containing them
HUP0001452A3 (en)	2000-10-30	Novel erythromycin derivatives, method of preparation and application as medicines
HUP0102854A3 (en)	2002-07-29	Cyanoiminoquinoxaline derivatives, process for their preparation, pharmaceutical compositions containing them and their use