HUE062446T2 - Vegyületek, készítmények és eljárások - Google Patents
Vegyületek, készítmények és eljárásokInfo
- Publication number
- HUE062446T2 HUE062446T2 HUE18850713A HUE18850713A HUE062446T2 HU E062446 T2 HUE062446 T2 HU E062446T2 HU E18850713 A HUE18850713 A HU E18850713A HU E18850713 A HUE18850713 A HU E18850713A HU E062446 T2 HUE062446 T2 HU E062446T2
- Authority
- HU
- Hungary
- Prior art keywords
- compositions
- compounds
- methods
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/14—Nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/08—Bridged systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pyrane Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762553750P | 2017-09-01 | 2017-09-01 | |
| US201762609267P | 2017-12-21 | 2017-12-21 | |
| US201862634721P | 2018-02-23 | 2018-02-23 | |
| US201862697281P | 2018-07-12 | 2018-07-12 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HUE062446T2 true HUE062446T2 (hu) | 2023-11-28 |
Family
ID=65526108
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HUE18850713A HUE062446T2 (hu) | 2017-09-01 | 2018-08-31 | Vegyületek, készítmények és eljárások |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US12139478B2 (hu) |
| EP (2) | EP3676297B1 (hu) |
| JP (3) | JP7382308B2 (hu) |
| CN (1) | CN111201245B (hu) |
| CA (1) | CA3072057A1 (hu) |
| DK (1) | DK3676297T3 (hu) |
| ES (1) | ES2952994T3 (hu) |
| FI (1) | FI3676297T3 (hu) |
| HU (1) | HUE062446T2 (hu) |
| MA (1) | MA50063A (hu) |
| PL (1) | PL3676297T3 (hu) |
| PT (1) | PT3676297T (hu) |
| SI (1) | SI3676297T1 (hu) |
| TW (1) | TW201920129A (hu) |
| WO (1) | WO2019046779A1 (hu) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3665156A4 (en) | 2017-08-09 | 2021-04-28 | Denali Therapeutics Inc. | COMPOUNDS, COMPOSITIONS, AND PROCEDURES |
| DK3676297T3 (da) | 2017-09-01 | 2023-08-14 | Denali Therapeutics Inc | Forbindelser, sammensætninger og fremgangsmåder |
| WO2019090088A1 (en) | 2017-11-02 | 2019-05-09 | Calico Life Sciences Llc | Modulators of the integrated stress pathway |
| SG11202005561XA (en) | 2017-12-13 | 2020-07-29 | Praxis Biotech LLC | Inhibitors of integrated stress response pathway |
| KR20210021519A (ko) | 2018-06-05 | 2021-02-26 | 프락시스 바이오테크 엘엘씨 | 통합 스트레스 반응 경로의 저해제 |
| TWI832295B (zh) | 2018-10-11 | 2024-02-11 | 美商嘉來克生命科學有限責任公司 | 整合應激路徑之前藥調節劑 |
| TWI877136B (zh) | 2019-02-13 | 2025-03-21 | 美商戴納立製藥公司 | 化合物、組合物及方法 |
| US12091392B2 (en) | 2019-02-13 | 2024-09-17 | Denali Therapeutics Inc. | Compounds, compositions and methods |
| EA202192900A1 (ru) * | 2019-04-23 | 2022-03-18 | Эвотек Интернешнл Гмбх | Модуляторы пути интегрированной реакции на стресс |
| EP3959198A1 (en) | 2019-04-23 | 2022-03-02 | Evotec International GmbH | Modulators of the integrated stress response pathway |
| PH12021552759A1 (en) * | 2019-04-30 | 2022-07-04 | Abbvie Inc | Substituted cycloalkyls as modulators of the integrated stress pathway |
| WO2020252207A1 (en) | 2019-06-12 | 2020-12-17 | Praxis Biotech LLC | Modulators of integrated stress response pathway |
| AU2021213289A1 (en) | 2020-01-28 | 2022-07-07 | Evotec International Gmbh | Modulators of the integrated stress response pathway |
| KR20220151635A (ko) * | 2020-03-11 | 2022-11-15 | 에보텍 인터내셔널 게엠베하 | 통합 스트레스 반응 경로의 조절제 |
| EP4232153A1 (en) | 2020-10-22 | 2023-08-30 | Evotec International GmbH | Modulators of the integrated stress response pathway |
| CN116761803A (zh) * | 2020-10-22 | 2023-09-15 | 埃沃特克国际有限责任公司 | 整合应激反应途径的调节剂 |
| EP4232447A1 (en) | 2020-10-22 | 2023-08-30 | Evotec International GmbH | Modulators of the integrated stress response pathway |
| EP4232154B1 (en) | 2020-10-22 | 2024-11-13 | Evotec International GmbH | Modulators of the integrated stress response pathway |
| MX2023004870A (es) * | 2020-10-30 | 2023-05-11 | Calico Life Sciences Llc | Moduladores de la via integrada del estres. |
| CN116768877A (zh) * | 2022-05-30 | 2023-09-19 | 中国药科大学 | Isr抑制剂及其制备方法和应用 |
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| US12091392B2 (en) | 2019-02-13 | 2024-09-17 | Denali Therapeutics Inc. | Compounds, compositions and methods |
| US20220177456A1 (en) | 2019-03-06 | 2022-06-09 | Denali Therapeutics Inc. | Compounds, compositions and methods |
| EP3959198A1 (en) | 2019-04-23 | 2022-03-02 | Evotec International GmbH | Modulators of the integrated stress response pathway |
| SG11202111970WA (en) | 2019-04-30 | 2021-11-29 | Calico Life Sciences Llc | Substituted cyclolakyls as modulators of the integrated stress pathway |
| PH12021552759A1 (en) | 2019-04-30 | 2022-07-04 | Abbvie Inc | Substituted cycloalkyls as modulators of the integrated stress pathway |
| AU2021213289A1 (en) | 2020-01-28 | 2022-07-07 | Evotec International Gmbh | Modulators of the integrated stress response pathway |
| WO2022133236A1 (en) | 2020-12-18 | 2022-06-23 | Denali Therapeutics Inc. | Solid forms of a compound |
| EP4543843A1 (en) | 2022-06-23 | 2025-04-30 | Denali Therapeutics Inc. | Process for preparing modulators of eukaryotic initiation factor 2b |
-
2018
- 2018-08-31 DK DK18850713.1T patent/DK3676297T3/da active
- 2018-08-31 CN CN201880063335.4A patent/CN111201245B/zh active Active
- 2018-08-31 JP JP2020511347A patent/JP7382308B2/ja active Active
- 2018-08-31 ES ES18850713T patent/ES2952994T3/es active Active
- 2018-08-31 WO PCT/US2018/049197 patent/WO2019046779A1/en unknown
- 2018-08-31 EP EP18850713.1A patent/EP3676297B1/en active Active
- 2018-08-31 HU HUE18850713A patent/HUE062446T2/hu unknown
- 2018-08-31 TW TW107130678A patent/TW201920129A/zh unknown
- 2018-08-31 MA MA050063A patent/MA50063A/fr unknown
- 2018-08-31 CA CA3072057A patent/CA3072057A1/en active Pending
- 2018-08-31 PL PL18850713.1T patent/PL3676297T3/pl unknown
- 2018-08-31 EP EP23173466.6A patent/EP4248965A3/en active Pending
- 2018-08-31 FI FIEP18850713.1T patent/FI3676297T3/fi active
- 2018-08-31 PT PT188507131T patent/PT3676297T/pt unknown
- 2018-08-31 US US16/643,168 patent/US12139478B2/en active Active
- 2018-08-31 SI SI201830964T patent/SI3676297T1/sl unknown
-
2023
- 2023-02-28 JP JP2023030214A patent/JP2023060020A/ja active Pending
-
2024
- 2024-04-08 JP JP2024062313A patent/JP2024086819A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| PT3676297T (pt) | 2023-08-29 |
| US20200331900A1 (en) | 2020-10-22 |
| CN111201245B (zh) | 2024-04-05 |
| EP4248965A2 (en) | 2023-09-27 |
| JP7382308B2 (ja) | 2023-11-16 |
| ES2952994T3 (es) | 2023-11-07 |
| EP3676297A4 (en) | 2021-04-28 |
| MA50063A (fr) | 2021-04-28 |
| CN111201245A (zh) | 2020-05-26 |
| CA3072057A1 (en) | 2019-03-07 |
| EP4248965A3 (en) | 2023-11-22 |
| PL3676297T3 (pl) | 2023-12-11 |
| US12139478B2 (en) | 2024-11-12 |
| EP3676297A1 (en) | 2020-07-08 |
| WO2019046779A1 (en) | 2019-03-07 |
| JP2024086819A (ja) | 2024-06-28 |
| EP3676297B1 (en) | 2023-05-17 |
| SI3676297T1 (sl) | 2023-12-29 |
| JP2020532506A (ja) | 2020-11-12 |
| DK3676297T3 (da) | 2023-08-14 |
| JP2023060020A (ja) | 2023-04-27 |
| TW201920129A (zh) | 2019-06-01 |
| FI3676297T3 (fi) | 2023-08-08 |
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