IL255042B - Bolaamphiphilic compounds, compositions and uses thereof - Google Patents
Bolaamphiphilic compounds, compositions and uses thereofInfo
- Publication number
- IL255042B IL255042B IL255042A IL25504217A IL255042B IL 255042 B IL255042 B IL 255042B IL 255042 A IL255042 A IL 255042A IL 25504217 A IL25504217 A IL 25504217A IL 255042 B IL255042 B IL 255042B
- Authority
- IL
- Israel
- Prior art keywords
- compositions
- bolaamphiphilic compounds
- bolaamphiphilic
- compounds
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
- A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers comprising non-phosphatidyl surfactants as bilayer-forming substances, e.g. cationic lipids or non-phosphatidyl liposomes coated or grafted with polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/5123—Organic compounds, e.g. fats, sugars
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Neurosurgery (AREA)
- Biophysics (AREA)
- Dispersion Chemistry (AREA)
- Neurology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Nanotechnology (AREA)
- Biochemistry (AREA)
- Hospice & Palliative Care (AREA)
- Optics & Photonics (AREA)
- Physics & Mathematics (AREA)
- Psychiatry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Dermatology (AREA)
- Immunology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201562148511P | 2015-04-16 | 2015-04-16 | |
US201562258773P | 2015-11-23 | 2015-11-23 | |
PCT/US2016/027726 WO2016168580A1 (en) | 2015-04-16 | 2016-04-15 | Bolaamphiphilic compounds, compositions and uses thereof |
Publications (2)
Publication Number | Publication Date |
---|---|
IL255042A0 IL255042A0 (en) | 2017-12-31 |
IL255042B true IL255042B (en) | 2022-04-01 |
Family
ID=57126121
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL255042A IL255042B (en) | 2015-04-16 | 2017-10-16 | Bolaamphiphilic compounds, compositions and uses thereof |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP3283060A4 (en) |
AU (1) | AU2016248992A1 (en) |
CA (1) | CA3018945A1 (en) |
IL (1) | IL255042B (en) |
WO (1) | WO2016168580A1 (en) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2022087175A1 (en) * | 2020-10-21 | 2022-04-28 | University Of San Diego | Multivalent terpene-based bolaamphiphiles for gene delivery |
KR20230097142A (en) | 2020-11-03 | 2023-06-30 | 온코나노 메디신, 인크. | Therapeutic pH Responsive Compositions |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2010128504A2 (en) * | 2009-05-04 | 2010-11-11 | Ben-Gurion University Of The Negev Research And Development Authority | Nano-sized particles comprising multi-headed amphiphiles for targeted drug delivery |
CA2883791A1 (en) * | 2012-09-04 | 2014-03-13 | Lauren Sciences Llc | Bolaamphiphilic compounds, compositions and uses thereof |
EP2892511B1 (en) * | 2012-09-04 | 2021-06-30 | Lauren Sciences LLC | Bolaamphiphilic compounds, compositions and uses thereof |
CA3233929A1 (en) * | 2012-09-04 | 2014-03-13 | Lauren Sciences Llc | Bolaamphiphilic compounds, compositions and uses thereof |
-
2016
- 2016-04-15 WO PCT/US2016/027726 patent/WO2016168580A1/en active Application Filing
- 2016-04-15 AU AU2016248992A patent/AU2016248992A1/en not_active Abandoned
- 2016-04-15 CA CA3018945A patent/CA3018945A1/en not_active Abandoned
- 2016-04-15 EP EP16780822.9A patent/EP3283060A4/en active Pending
-
2017
- 2017-10-16 IL IL255042A patent/IL255042B/en unknown
Also Published As
Publication number | Publication date |
---|---|
EP3283060A1 (en) | 2018-02-21 |
EP3283060A4 (en) | 2018-12-19 |
AU2016248992A1 (en) | 2017-12-07 |
IL255042A0 (en) | 2017-12-31 |
CA3018945A1 (en) | 2016-10-20 |
WO2016168580A1 (en) | 2016-10-20 |
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