AU2001249417A1 - Chiral imidazoyl intermediates for the synthesis of 2-(4-imidazoyl)-cyclopropyl derivatives - Google Patents
Chiral imidazoyl intermediates for the synthesis of 2-(4-imidazoyl)-cyclopropyl derivativesInfo
- Publication number
- AU2001249417A1 AU2001249417A1 AU2001249417A AU4941701A AU2001249417A1 AU 2001249417 A1 AU2001249417 A1 AU 2001249417A1 AU 2001249417 A AU2001249417 A AU 2001249417A AU 4941701 A AU4941701 A AU 4941701A AU 2001249417 A1 AU2001249417 A1 AU 2001249417A1
- Authority
- AU
- Australia
- Prior art keywords
- imidazoyl
- chiral
- intermediates
- synthesis
- cyclopropyl derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- -1 imidazoyl Chemical group 0.000 title 2
- 230000015572 biosynthetic process Effects 0.000 title 1
- 239000000543 intermediate Substances 0.000 title 1
- 238000003786 synthesis reaction Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US19972200P | 2000-04-26 | 2000-04-26 | |
| US60199722 | 2000-04-26 | ||
| PCT/US2001/009445 WO2001081317A1 (en) | 2000-04-26 | 2001-03-26 | Chiral imidazoyl intermediates for the synthesis of 2-(4-imidazoyl)-cyclopropyl derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2001249417A1 true AU2001249417A1 (en) | 2001-11-07 |
Family
ID=22738752
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2001249417A Abandoned AU2001249417A1 (en) | 2000-04-26 | 2001-03-26 | Chiral imidazoyl intermediates for the synthesis of 2-(4-imidazoyl)-cyclopropyl derivatives |
Country Status (3)
| Country | Link |
|---|---|
| US (1) | US20010047100A1 (en) |
| AU (1) | AU2001249417A1 (en) |
| WO (1) | WO2001081317A1 (en) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK2395002T3 (en) | 2005-11-08 | 2014-09-08 | Vertex Pharma | Pharmaceutical composition containing a heterocyclic modulator of ATP-binding cassette transporters |
| US7671221B2 (en) | 2005-12-28 | 2010-03-02 | Vertex Pharmaceuticals Incorporated | Modulators of ATP-Binding Cassette transporters |
| US7754739B2 (en) | 2007-05-09 | 2010-07-13 | Vertex Pharmaceuticals Incorporated | Modulators of CFTR |
| EP1942104A1 (en) | 2006-12-20 | 2008-07-09 | sanofi-aventis | Heteroarylcyclopropanecarboxamides and their use as pharmaceuticals |
| CN102863432B (en) | 2007-05-09 | 2016-09-07 | 沃泰克斯药物股份有限公司 | CFTR conditioning agent |
| MX2010006183A (en) | 2007-12-07 | 2010-10-15 | Vertex Pharma | Processes for producing cycloalkylcarboxiamido-pyridine benzoic acids. |
| SG186638A1 (en) | 2007-12-07 | 2013-01-30 | Vertex Pharma | Solid forms of 3-(6-(1-(2,2-difluorobenzo[d][1,3] dioxol-5-yl) cyclopropanecarboxamido)-3-methylpyridin-2-yl) benzoic acid |
| NZ703814A (en) | 2008-02-28 | 2016-06-24 | Vertex Pharma | Heteroaryl derivatives as cftr modulators |
| CN106943403A (en) | 2010-04-07 | 2017-07-14 | 弗特克斯药品有限公司 | Pharmaceutical composition and its medication |
| PL2806859T3 (en) | 2012-01-25 | 2019-11-29 | Vertex Pharma | Formulations of 3- (6- (1- (2,2-difluorobenzo [d] [1,3] dioxol-5-yl) cyclopropanecarboxamido) -3-methylpyridin-2-yl) benzoic acid |
| PT3068392T (en) | 2013-11-12 | 2021-05-14 | Vertex Pharma | Process of preparing pharmaceutical compositions for the treatment of cftr mediated diseases |
| CN107110831B (en) | 2014-11-18 | 2020-02-21 | 弗特克斯药品有限公司 | Methods for conducting high-throughput experiments with high-performance liquid chromatography |
| MA49858A (en) | 2017-08-09 | 2021-04-28 | Denali Therapeutics Inc | COMPOUNDS, COMPOSITIONS AND PROCESSES |
| WO2019046779A1 (en) | 2017-09-01 | 2019-03-07 | Denali Therapeutics Inc. | Compounds, compositions and methods |
| MA54959A (en) | 2019-02-13 | 2021-12-22 | Denali Therapeutics Inc | COMPOUNDS, COMPOSITIONS AND METHODS |
| AU2020223228A1 (en) * | 2019-02-13 | 2021-08-26 | Denali Therapeutics Inc. | Compounds, compositions and methods |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2686084B1 (en) * | 1992-01-10 | 1995-12-22 | Bioprojet Soc Civ | NEW IMIDAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATIONS. |
-
2001
- 2001-03-26 AU AU2001249417A patent/AU2001249417A1/en not_active Abandoned
- 2001-03-26 US US09/817,700 patent/US20010047100A1/en not_active Abandoned
- 2001-03-26 WO PCT/US2001/009445 patent/WO2001081317A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| WO2001081317A1 (en) | 2001-11-01 |
| US20010047100A1 (en) | 2001-11-29 |
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