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HUE043894T2 - Koagulációt elõsegítõ vegyületek és alkalmazásuk módszerei - Google Patents

Koagulációt elõsegítõ vegyületek és alkalmazásuk módszerei

Info

Publication number
HUE043894T2
HUE043894T2 HUE12797036A HUE12797036A HUE043894T2 HU E043894 T2 HUE043894 T2 HU E043894T2 HU E12797036 A HUE12797036 A HU E12797036A HU E12797036 A HUE12797036 A HU E12797036A HU E043894 T2 HUE043894 T2 HU E043894T2
Authority
HU
Hungary
Prior art keywords
pro
methods
coagulant compounds
coagulant
compounds
Prior art date
Application number
HUE12797036A
Other languages
English (en)
Inventor
Karina Thorn
Garabet G Toby
Adam R Mezo
Original Assignee
Bioverativ Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bioverativ Therapeutics Inc filed Critical Bioverativ Therapeutics Inc
Publication of HUE043894T2 publication Critical patent/HUE043894T2/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/36—Blood coagulation or fibrinolysis factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Hematology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Toxicology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Separation Of Suspended Particles By Flocculating Agents (AREA)
  • Medicinal Preparation (AREA)
HUE12797036A 2011-06-10 2012-06-09 Koagulációt elõsegítõ vegyületek és alkalmazásuk módszerei HUE043894T2 (hu)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201161495818P 2011-06-10 2011-06-10
US201161496540P 2011-06-13 2011-06-13
US201161496542P 2011-06-13 2011-06-13
US201161496541P 2011-06-13 2011-06-13
US201161496543P 2011-06-13 2011-06-13
US201261600237P 2012-02-17 2012-02-17
US201261605540P 2012-03-01 2012-03-01

Publications (1)

Publication Number Publication Date
HUE043894T2 true HUE043894T2 (hu) 2019-09-30

Family

ID=47296790

Family Applications (1)

Application Number Title Priority Date Filing Date
HUE12797036A HUE043894T2 (hu) 2011-06-10 2012-06-09 Koagulációt elõsegítõ vegyületek és alkalmazásuk módszerei

Country Status (14)

Country Link
US (1) US9486507B2 (hu)
EP (2) EP3527218A1 (hu)
AU (1) AU2012267484B2 (hu)
CA (1) CA2838833A1 (hu)
CY (1) CY1121509T1 (hu)
DK (1) DK2717898T3 (hu)
ES (1) ES2724778T3 (hu)
HR (1) HRP20190494T1 (hu)
HU (1) HUE043894T2 (hu)
LT (1) LT2717898T (hu)
PL (1) PL2717898T3 (hu)
PT (1) PT2717898T (hu)
SI (1) SI2717898T1 (hu)
WO (1) WO2012170969A2 (hu)

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EP2822577B1 (en) 2012-02-15 2019-02-06 Bioverativ Therapeutics Inc. Recombinant factor viii proteins
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US10202595B2 (en) 2012-06-08 2019-02-12 Bioverativ Therapeutics Inc. Chimeric clotting factors
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WO2017176007A1 (ko) * 2016-04-06 2017-10-12 (주)알테오젠 변형항체를 포함하는 항체-약물 접합체
EP3481945A4 (en) 2016-07-11 2020-07-29 Board of Regents, The University of Texas System RECOMBINATION POLYPEPTIDES INCLUDING SELENOCYSTEIN AND THEIR PRODUCTION PROCESS
CN106279437B (zh) * 2016-08-19 2017-10-31 安源医药科技（上海）有限公司 高糖基化人凝血因子viii融合蛋白及其制备方法与用途
CN106317226B (zh) 2016-08-19 2017-09-05 安源医药科技（上海）有限公司 用于构建融合蛋白的连接肽
CN109803679A (zh) 2016-08-30 2019-05-24 得克萨斯州大学系统董事会 在基因组重新编码生物体中生产硒代生物制剂
WO2018102317A1 (en) * 2016-11-29 2018-06-07 The Regents Of The University Of California Modulation of p53 for the treatment of cancer
MA46967A (fr) * 2016-12-02 2019-10-09 Bioverativ Therapeutics Inc Méthodes de traitement de l'arthropathie hémophilique à l'aide de facteurs de coagulation chimériques
US11519917B2 (en) 2017-04-13 2022-12-06 The Regents Of The University Of Michigan Assay for quantifying polyphosphates
TW202015723A (zh) 2018-05-18 2020-05-01 美商百歐維拉提夫治療公司 治療ａ型血友病的方法
WO2020084161A1 (en) * 2018-10-26 2020-04-30 Vrije Universiteit Brussel New tools for improving gene therapy and use thereof
CN109507966A (zh) * 2018-11-20 2019-03-22 东华大学 一种面向纬编面料生产的智能管控系统
CN113101413B (zh) * 2020-01-13 2022-04-08 中国科学院苏州纳米技术与纳米仿生研究所 有序水凝胶纤维支架、其制备方法及应用

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EP2717898A2 (en) 2014-04-16
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