HN2005000030A - Derivados de sulfonamida para el tratamiento de enfermedades - Google Patents
Derivados de sulfonamida para el tratamiento de enfermedadesInfo
- Publication number
- HN2005000030A HN2005000030A HN2005000030A HN2005000030A HN2005000030A HN 2005000030 A HN2005000030 A HN 2005000030A HN 2005000030 A HN2005000030 A HN 2005000030A HN 2005000030 A HN2005000030 A HN 2005000030A HN 2005000030 A HN2005000030 A HN 2005000030A
- Authority
- HN
- Honduras
- Prior art keywords
- alkyl
- group
- cycloalkyl
- diseases
- treatment
- Prior art date
Links
- 201000010099 disease Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- 229940124530 sulfonamide Drugs 0.000 title 1
- 150000003456 sulfonamides Chemical class 0.000 title 1
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 4
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000001475 halogen functional group Chemical group 0.000 abstract 1
- 230000000155 isotopic effect Effects 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 125000003386 piperidinyl group Chemical group 0.000 abstract 1
- 125000004076 pyridyl group Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
- 125000001412 tetrahydropyranyl group Chemical group 0.000 abstract 1
- 125000004632 tetrahydrothiopyranyl group Chemical group S1C(CCCC1)* 0.000 abstract 1
- 125000000876 trifluoromethoxy group Chemical group FC(F)(F)O* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
- C07C323/39—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton at least one of the nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom
- C07C323/40—Y being a hydrogen or a carbon atom
- C07C323/42—Y being a carbon atom of a six-membered aromatic ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/16—Central respiratory analeptics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/01—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms
- C07C311/02—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
- C07C311/08—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
- C07D295/027—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
- C07D295/03—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring with the ring nitrogen atoms directly attached to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/08—One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Hydrogenated Pyridines (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Pyridine Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Abstract
1.- Un compuesto de la formula general (1):en el que el grupo (CH2)n-C(=O)Q1 esta en posicion relativa meta o para, R1 y R2 se seleccionan independientemente de H y alquilo C1-C4, n es 0, 1 o 2 y Q1 es un grupo que se selecciona de, y un grupo *-NR11-Q2-A, en el que p es 1 o 2, Q2 es un alquileno C1-C4, R11 es H o alquilo C1-C4 y A es piridilo, cicloalquilo C3-C10, siendo dicho cicloalquilo, que opcionalmente esta puenteado por uno o mas atomos de carbono, tetrahidropiranilo, piperidinilo opcionalmente sustituido con bencilo, tetrahidrotiopiranilo o un grupo en el que R3, R4, R5, R6 y R7 son iguales o diferentes y se seleccionan de H, alquilo C1-C4, OR8, SR9, halo, CN, CF3, OCF3, COOR9, SO2NR9R10, CONR9R10, NR9R10, NHCOR10 y fenilo;en los que R8 es alquilo C1-C4 y R9 y R10 son iguales o diferentes y se seleccionan de H o alquilo C1-C4 y el * representa el punto de union al grupo carbonilo;o, si fuera apropiado, sus sales y/o isomeros, tautomeros, solvatos o variaciones isotopicas farmacéuticamente aceptables.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP04290168 | 2004-01-22 | ||
| GB0406388A GB0406388D0 (en) | 2004-03-22 | 2004-03-22 | Sulfonamide derivatives for the treatment of diseases |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HN2005000030A true HN2005000030A (es) | 2009-04-20 |
Family
ID=43063961
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HN2005000030A HN2005000030A (es) | 2004-01-22 | 2005-01-21 | Derivados de sulfonamida para el tratamiento de enfermedades |
Country Status (40)
| Country | Link |
|---|---|
| US (1) | US7351742B2 (es) |
| EP (1) | EP1708992B1 (es) |
| JP (1) | JP4036343B2 (es) |
| KR (1) | KR100785580B1 (es) |
| CN (1) | CN1910144B (es) |
| AP (1) | AP2378A (es) |
| AR (1) | AR047510A1 (es) |
| AT (1) | ATE369333T1 (es) |
| AU (1) | AU2005214154B2 (es) |
| BR (1) | BRPI0507041A (es) |
| CA (1) | CA2553293C (es) |
| CO (1) | CO5720993A2 (es) |
| CY (1) | CY1106894T1 (es) |
| DE (1) | DE602005001929T2 (es) |
| DK (1) | DK1708992T3 (es) |
| DO (1) | DOP2005000004A (es) |
| EA (1) | EA009735B1 (es) |
| EC (1) | ECSP066701A (es) |
| ES (1) | ES2289691T3 (es) |
| GE (1) | GEP20084452B (es) |
| HN (1) | HN2005000030A (es) |
| HR (1) | HRP20070452T3 (es) |
| IL (1) | IL176629A (es) |
| MA (1) | MA28303A1 (es) |
| ME (1) | ME00557A (es) |
| MY (1) | MY139690A (es) |
| NL (1) | NL1028086C2 (es) |
| NO (1) | NO20063761L (es) |
| NZ (1) | NZ548235A (es) |
| OA (1) | OA13361A (es) |
| PA (1) | PA8621901A1 (es) |
| PE (1) | PE20050765A1 (es) |
| PL (1) | PL1708992T3 (es) |
| PT (1) | PT1708992E (es) |
| RS (1) | RS50538B (es) |
| SI (1) | SI1708992T1 (es) |
| TW (1) | TWI273099B (es) |
| UA (1) | UA82283C2 (es) |
| UY (1) | UY28724A1 (es) |
| WO (1) | WO2005080324A1 (es) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GT200500281A (es) | 2004-10-22 | 2006-04-24 | Novartis Ag | Compuestos organicos. |
| AU2006271356A1 (en) * | 2005-07-18 | 2007-01-25 | Pfizer Limited | Process for the preparation of sulfonamide derivatives |
| GB0516313D0 (en) | 2005-08-08 | 2005-09-14 | Argenta Discovery Ltd | Azole derivatives and their uses |
| WO2007017670A1 (en) | 2005-08-08 | 2007-02-15 | Argenta Discovery Ltd. | Bicyclo[2.2.]hept-7-ylamine derivatives and their uses |
| GB0601951D0 (en) | 2006-01-31 | 2006-03-15 | Novartis Ag | Organic compounds |
| NZ570693A (en) | 2006-03-20 | 2011-02-25 | Pfizer Ltd | Amine derivatives |
| SI2013211T1 (sl) | 2006-04-21 | 2012-07-31 | Novartis Ag | Purinski derivati za uporabo kot agonisti receptorja adenozina A A |
| WO2008041095A1 (en) * | 2006-10-04 | 2008-04-10 | Pfizer Limited | Sulfonamide derivatives as adrenergic agonists and muscarinic antagonists |
| DE102007018151A1 (de) | 2007-04-16 | 2008-10-23 | Günenthal GmbH | Neue Vanilloid-Rezeptor Liganden und ihre Verwendung zur Herstellung von Arzneimitteln |
| US7713463B1 (en) * | 2007-11-13 | 2010-05-11 | Nuvasive, Inc. | Method of manufacturing embroidered surgical implants |
| PL2231642T3 (pl) | 2008-01-11 | 2014-04-30 | Novartis Ag | Pirymidyny jako inhibitory kinazy |
| US8263623B2 (en) * | 2008-07-11 | 2012-09-11 | Pfizer Inc. | Triazol derivatives useful for the treatment of diseases |
| US8236786B2 (en) | 2008-08-07 | 2012-08-07 | Pulmagen Therapeutics (Inflammation) Limited | Respiratory disease treatment |
| ES2442343T3 (es) | 2008-12-30 | 2014-02-11 | Pulmagen Therapeutics (Inflammation) Limited | Compuestos de sulfonamida para el tratamiento de trastornos respiratorios |
| MX2011011156A (es) | 2009-04-23 | 2011-11-04 | Theravance Inc | COMPUESTOS DIAMIDA QUE TIENE ACTIVIDAD COMO ANTAGONISTAS DE LOS RECEPTORES MUSCARINICOS Y COMO AGONISTAS DE LOS RECEPTORES ANDRENERGICOS ß2. |
| WO2010136940A1 (en) | 2009-05-29 | 2010-12-02 | Pfizer Limited | Novel glucocorticoid receptor agonists |
| WO2010150014A1 (en) | 2009-06-24 | 2010-12-29 | Pulmagen Therapeutics (Inflammation) Limited | 5r- 5 -deuterated glitazones for respiratory disease treatment |
| JP5801997B2 (ja) | 2009-07-07 | 2015-10-28 | ファイザー・リミテッドＰｆｉｚｅｒ Ｌｉｍｉｔｅｄ | 薬品の組合せを吸入するための投薬ユニット、投薬ユニットのパック、および吸入器 |
| GB0918924D0 (en) | 2009-10-28 | 2009-12-16 | Vantia Ltd | Azaindole derivatives |
| GB0918922D0 (en) | 2009-10-28 | 2009-12-16 | Vantia Ltd | Aminopyridine derivatives |
| GB0918923D0 (en) | 2009-10-28 | 2009-12-16 | Vantia Ltd | Aminothiazole derivatives |
| WO2011098746A1 (en) | 2010-02-09 | 2011-08-18 | Pulmagen Therapeutics (Inflammation) Limited | Crystalline acid addition salts of ( 5r) -enanti0mer of pioglitazone |
| GB201002224D0 (en) | 2010-02-10 | 2010-03-31 | Argenta Therapeutics Ltd | Respiratory disease treatment |
| GB201002243D0 (en) | 2010-02-10 | 2010-03-31 | Argenta Therapeutics Ltd | Respiratory disease treatment |
| WO2012034095A1 (en) | 2010-09-09 | 2012-03-15 | Irm Llc | Compounds and compositions as trk inhibitors |
| UY33597A (es) | 2010-09-09 | 2012-04-30 | Irm Llc | Compuestos y composiciones como inhibidores de la trk |
| GEP20156285B (en) | 2011-02-25 | 2015-05-11 | Aierem Elelsi | Compounds and compositions as trk inhibitors |
| MY169479A (en) | 2011-06-10 | 2019-04-15 | Chiesi Farm Spa | Compounds having muscarinic receptor antagonist and beta2 adrenergic receptor agonist activity |
| HRP20180915T1 (hr) | 2012-12-06 | 2018-07-27 | Chiesi Farmaceutici S.P.A. | Spojevi koji imaju aktivnost kao antagonist muskarinskog receptora i kao agonist beta2 adrenergijskog receptora |
| RU2661877C2 (ru) | 2012-12-06 | 2018-07-20 | КЬЕЗИ ФАРМАЧЕУТИЧИ С.п.А. | Соединения, обладающие активностью антагонистов мускариновых рецепторов и агонистов бета-2-адренергических рецепторов |
| AU2021296221A1 (en) | 2020-06-26 | 2023-02-02 | Mylan Pharma Uk Limited | Formulations including 5-(3-(3-hydroxyphenoxy)azetidin-1-yl)-5-methyl-2,2-diphenylhexanamide |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4404224A (en) | 1981-12-02 | 1983-09-13 | American Cyanamid Company | Alkanesulfonanilide derivatives and pharmaceutically acceptable acid addition salts thereof for increasing the growth rate and/or improving the lean meat to fat ratio of warm blooded animals |
| US4540581A (en) | 1984-01-31 | 1985-09-10 | Bristol-Myers Company | Topical nonsteroidal anti-inflammatory compositions and uses |
| KR0166088B1 (ko) | 1990-01-23 | 1999-01-15 | . | 수용해도가 증가된 시클로덱스트린 유도체 및 이의 용도 |
| US5376645A (en) | 1990-01-23 | 1994-12-27 | University Of Kansas | Derivatives of cyclodextrins exhibiting enhanced aqueous solubility and the use thereof |
| US5776983A (en) * | 1993-12-21 | 1998-07-07 | Bristol-Myers Squibb Company | Catecholamine surrogates useful as β3 agonists |
| JPH10218861A (ja) | 1997-02-04 | 1998-08-18 | Yamanouchi Pharmaceut Co Ltd | 新規なフェネタノール誘導体又はその塩 |
| GB9711643D0 (en) | 1997-06-05 | 1997-07-30 | Janssen Pharmaceutica Nv | Glass thermoplastic systems |
| US6362371B1 (en) | 1998-06-08 | 2002-03-26 | Advanced Medicine, Inc. | β2- adrenergic receptor agonists |
| US20020143034A1 (en) * | 1998-12-30 | 2002-10-03 | Fujisawa Pharmaceutical Co. Ltd. | Aminoalcohol derivatives and their use as beta 3 adrenergic agonists |
| OA11558A (en) | 1999-12-08 | 2004-06-03 | Advanced Medicine Inc | Beta 2-adrenergic receptor agonists. |
| AUPQ841300A0 (en) | 2000-06-27 | 2000-07-20 | Fujisawa Pharmaceutical Co., Ltd. | New aminoalcohol derivatives |
| US6465501B2 (en) | 2000-07-17 | 2002-10-15 | Wyeth | Azolidines as β3 adrenergic receptor agonists |
| US7048994B2 (en) | 2001-02-23 | 2006-05-23 | Teijin Limited | Laminated polyester film and magnetic recording medium |
| US20030229058A1 (en) * | 2001-11-13 | 2003-12-11 | Moran Edmund J. | Aryl aniline beta2 adrenergic receptor agonists |
| WO2003099764A1 (en) * | 2002-05-28 | 2003-12-04 | Theravance, Inc. | ALKOXY ARYL β2 ADRENERGIC RECEPTOR AGONISTS |
| EP1477167A1 (en) * | 2003-05-15 | 2004-11-17 | Pfizer Limited | [(2-hydroxy-2-(4-hydroxy-3-hydroxymethylphenyl)-ethylamino)-propyl] phenyl derivatives as beta2 agonists |
-
2005
- 2005-01-12 JP JP2006550334A patent/JP4036343B2/ja not_active Expired - Fee Related
- 2005-01-12 OA OA1200600233A patent/OA13361A/en unknown
- 2005-01-12 WO PCT/IB2005/000112 patent/WO2005080324A1/en active Application Filing
- 2005-01-12 AT AT05702274T patent/ATE369333T1/de active
- 2005-01-12 HR HR20070452T patent/HRP20070452T3/xx unknown
- 2005-01-12 AU AU2005214154A patent/AU2005214154B2/en not_active Ceased
- 2005-01-12 RS RSP-2007/0409A patent/RS50538B/sr unknown
- 2005-01-12 CN CN2005800030044A patent/CN1910144B/zh not_active Expired - Fee Related
- 2005-01-12 ME MEP-736/08A patent/ME00557A/xx unknown
- 2005-01-12 NZ NZ548235A patent/NZ548235A/en not_active IP Right Cessation
- 2005-01-12 DE DE602005001929T patent/DE602005001929T2/de not_active Expired - Lifetime
- 2005-01-12 EA EA200601141A patent/EA009735B1/ru not_active IP Right Cessation
- 2005-01-12 AP AP2006003671A patent/AP2378A/xx active
- 2005-01-12 DK DK05702274T patent/DK1708992T3/da active
- 2005-01-12 KR KR1020067014814A patent/KR100785580B1/ko not_active Expired - Fee Related
- 2005-01-12 PT PT05702274T patent/PT1708992E/pt unknown
- 2005-01-12 GE GEAP20059537A patent/GEP20084452B/en unknown
- 2005-01-12 EP EP05702274A patent/EP1708992B1/en not_active Expired - Lifetime
- 2005-01-12 PL PL05702274T patent/PL1708992T3/pl unknown
- 2005-01-12 ES ES05702274T patent/ES2289691T3/es not_active Expired - Lifetime
- 2005-01-12 CA CA2553293A patent/CA2553293C/en not_active Expired - Fee Related
- 2005-01-12 BR BRPI0507041-4A patent/BRPI0507041A/pt not_active IP Right Cessation
- 2005-01-12 SI SI200530059T patent/SI1708992T1/sl unknown
- 2005-01-18 MY MYPI20050195A patent/MY139690A/en unknown
- 2005-01-18 TW TWSULFONAMIA patent/TWI273099B/zh not_active IP Right Cessation
- 2005-01-19 US US11/038,416 patent/US7351742B2/en not_active Expired - Fee Related
- 2005-01-20 DO DO2005000004A patent/DOP2005000004A/es unknown
- 2005-01-20 PE PE2005000078A patent/PE20050765A1/es not_active Application Discontinuation
- 2005-01-20 AR ARP050100206A patent/AR047510A1/es unknown
- 2005-01-21 HN HN2005000030A patent/HN2005000030A/es unknown
- 2005-01-21 UY UY28724A patent/UY28724A1/es unknown
- 2005-01-21 NL NL1028086A patent/NL1028086C2/nl not_active IP Right Cessation
- 2005-01-21 PA PA20058621901A patent/PA8621901A1/es unknown
- 2005-12-01 UA UAA200608230A patent/UA82283C2/uk unknown
-
2006
- 2006-06-29 IL IL176629A patent/IL176629A/en not_active IP Right Cessation
- 2006-07-13 EC EC2006006701A patent/ECSP066701A/es unknown
- 2006-07-18 CO CO06070683A patent/CO5720993A2/es not_active Application Discontinuation
- 2006-07-21 MA MA29202A patent/MA28303A1/fr unknown
- 2006-08-22 NO NO20063761A patent/NO20063761L/no not_active Application Discontinuation
-
2007
- 2007-09-27 CY CY20071101245T patent/CY1106894T1/el unknown
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