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HK1219111A1 - 通過抑制' -相互作用蛋白的 末端' 的天然反義轉錄物而治療 相關疾病 - Google Patents

通過抑制' -相互作用蛋白的 末端' 的天然反義轉錄物而治療 相關疾病

Info

Publication number
HK1219111A1
HK1219111A1 HK16107076.4A HK16107076A HK1219111A1 HK 1219111 A1 HK1219111 A1 HK 1219111A1 HK 16107076 A HK16107076 A HK 16107076A HK 1219111 A1 HK1219111 A1 HK 1219111A1
Authority
HK
Hong Kong
Prior art keywords
inhibiting
related diseases
interacting protein
antisense transcript
natural antisense
Prior art date
Application number
HK16107076.4A
Other languages
English (en)
Inventor
Joseph Collard
Sherman Olga Khorkova
Carlos Coito
Original Assignee
Curna Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Curna Inc filed Critical Curna Inc
Publication of HK1219111A1 publication Critical patent/HK1219111A1/zh

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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
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    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
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    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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    • A61P3/00—Drugs for disorders of the metabolism
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P3/00—Drugs for disorders of the metabolism
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    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
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    • C12N2310/00—Structure or type of the nucleic acid
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    • C12N2310/11—Antisense
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    • C12N2310/00—Structure or type of the nucleic acid
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/136—Screening for pharmacological compounds

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  • Neurosurgery (AREA)
  • Neurology (AREA)
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  • Heart & Thoracic Surgery (AREA)
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HK16107076.4A 2009-08-21 2016-06-20 通過抑制' -相互作用蛋白的 末端' 的天然反義轉錄物而治療 相關疾病 HK1219111A1 (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US23588509P 2009-08-21 2009-08-21

Publications (1)

Publication Number Publication Date
HK1219111A1 true HK1219111A1 (zh) 2017-03-24

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
HK16107076.4A HK1219111A1 (zh) 2009-08-21 2016-06-20 通過抑制' -相互作用蛋白的 末端' 的天然反義轉錄物而治療 相關疾病

Country Status (8)

Country Link
US (2) US8791087B2 (zh)
EP (2) EP2467482A4 (zh)
JP (1) JP5943836B2 (zh)
KR (1) KR101805213B1 (zh)
CN (1) CN102482670B (zh)
CA (1) CA2771228C (zh)
HK (1) HK1219111A1 (zh)
WO (1) WO2011022606A2 (zh)

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