HK1215433A1 - 製備苯並氧氮雜䓬化合物的方法 - Google Patents

製備苯並氧氮雜䓬化合物的方法

Info

Publication number: HK1215433A1
Authority: HK; Hong Kong
Prior art keywords: making; benzoxazepin compounds; compounds; making benzoxazepin; benzoxazepin
Prior art date: 2013-03-13

Application number

HK16103386.8A

Other languages

English (en)

Inventor

Remy Angelaud

Danial R Beaudry

Diane E Carrera

Sushant Malhotra

Travis Remarchuk

Frederic St-Jean

Original Assignee

Hoffmann La Roche

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2013-03-13

Filing date

2016-03-23

Publication date

2016-08-26

2016-03-23 Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche

2016-08-26 Publication of HK1215433A1 publication Critical patent/HK1215433A1/zh

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
- A61K31/4162—1,2-Diazoles condensed with heterocyclic ring systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4196—1,2,4-Triazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/553—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one oxygen as ring hetero atoms, e.g. loxapine, staurosporine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Epidemiology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Oncology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Plural Heterocyclic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

HK16103386.8A 2013-03-13 2016-03-23 製備苯並氧氮雜䓬化合物的方法 HK1215433A1 (zh)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US201361779619P	2013-03-13	2013-03-13
PCT/EP2014/054786 WO2014140073A1 (en)	2013-03-13	2014-03-12	Process for making benzoxazepin compounds

Publications (1)

Publication Number	Publication Date
HK1215433A1 true HK1215433A1 (zh)	2016-08-26

Family

ID=50241450

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
HK16103386.8A HK1215433A1 (zh)	2013-03-13	2016-03-23	製備苯並氧氮雜䓬化合物的方法

Country Status (16)

Country	Link
US (1)	US9303043B2 (zh)
EP (3)	EP3845540A1 (zh)
JP (6)	JP6363120B2 (zh)
KR (3)	KR20180070715A (zh)
CN (2)	CN105377856B (zh)
AR (1)	AR095365A1 (zh)
AU (3)	AU2014230812B2 (zh)
BR (1)	BR112015020716A2 (zh)
CA (6)	CA3005112A1 (zh)
HK (1)	HK1215433A1 (zh)
IL (1)	IL240793A0 (zh)
MX (1)	MX2015011438A (zh)
NZ (1)	NZ711192A (zh)
RU (2)	RU2018109979A (zh)
SG (2)	SG10201706760YA (zh)
WO (1)	WO2014140073A1 (zh)

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CN107995911B (zh)	2015-07-02	2020-08-04	豪夫迈·罗氏有限公司	苯并氧氮杂*噁唑烷酮化合物及其使用方法
CN112062778B (zh)	2015-07-02	2024-04-19	豪夫迈·罗氏有限公司	苯并氧氮杂䓬噁唑烷酮化合物及其使用方法
CN105906635A (zh) *	2016-06-08	2016-08-31	上海大学	全氟烷基苯并氮杂*并喹喔啉衍生物及其合成方法
EP3492452B1 (en) *	2016-07-29	2022-08-31	Japan Tobacco Inc.	Production method for pyrazole-amide compound
TW201813963A (zh)	2016-09-23	2018-04-16	美商基利科學股份有限公司	磷脂醯肌醇3-激酶抑制劑
TW201815787A (zh)	2016-09-23	2018-05-01	美商基利科學股份有限公司	磷脂醯肌醇3-激酶抑制劑
TW201825465A (zh)	2016-09-23	2018-07-16	美商基利科學股份有限公司	磷脂醯肌醇3-激酶抑制劑
ES2953833T3 (es)	2016-12-15	2023-11-16	Hoffmann La Roche	La invención se refiere a procedimientos de preparación de compuestos de benzoxacepina oxazolidinona e intermedios útiles
CN108752237A (zh) *	2018-07-05	2018-11-06	四川青木制药有限公司	一种对氨基苯甲脒盐酸盐的新制备方法
CN113195000A (zh)	2018-12-21	2021-07-30	第一三共株式会社	抗体-药物缀合物和激酶抑制剂的组合

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AU1228100A (en) *	1998-10-23	2000-05-15	Dow Agrosciences Llc	3-(substituted phenyl)-5-(substituted cyclopropyl)-1,2,4-triazole compounds
JP4463548B2 (ja)	2001-07-12	2010-05-19	リアクサ・リミテッド	マイクロカプセル化触媒、及びその製造法と使用法
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KR101689946B1 (ko)	2012-06-08	2016-12-26	에프. 호프만-라 로슈 아게	암의 치료를 위한 포스포이노시타이드 3 키나제 억제제 화합물 및 화학치료제의 돌연변이체 선택성 및 조합물

2014
- 2014-03-12 KR KR1020187016976A patent/KR20180070715A/ko not_active Withdrawn
- 2014-03-12 BR BR112015020716A patent/BR112015020716A2/pt not_active Application Discontinuation
- 2014-03-12 CA CA3005112A patent/CA3005112A1/en not_active Abandoned
- 2014-03-12 CA CA2897618A patent/CA2897618A1/en not_active Abandoned
- 2014-03-12 RU RU2018109979A patent/RU2018109979A/ru not_active Application Discontinuation
- 2014-03-12 KR KR1020157024484A patent/KR101821468B1/ko not_active Expired - Fee Related
- 2014-03-12 US US14/205,634 patent/US9303043B2/en active Active
- 2014-03-12 KR KR1020177016062A patent/KR101871133B1/ko not_active Expired - Fee Related
- 2014-03-12 SG SG10201706760YA patent/SG10201706760YA/en unknown
- 2014-03-12 RU RU2015138488A patent/RU2649976C2/ru not_active IP Right Cessation
- 2014-03-12 EP EP20204345.1A patent/EP3845540A1/en active Pending
- 2014-03-12 EP EP14709314.0A patent/EP2970329A1/en not_active Withdrawn
- 2014-03-12 CA CA2948765A patent/CA2948765A1/en not_active Abandoned
- 2014-03-12 MX MX2015011438A patent/MX2015011438A/es unknown
- 2014-03-12 NZ NZ711192A patent/NZ711192A/en not_active IP Right Cessation
- 2014-03-12 AU AU2014230812A patent/AU2014230812B2/en not_active Ceased
- 2014-03-12 CN CN201480015055.8A patent/CN105377856B/zh active Active
- 2014-03-12 CA CA3005118A patent/CA3005118A1/en not_active Abandoned
- 2014-03-12 JP JP2015562108A patent/JP6363120B2/ja active Active
- 2014-03-12 WO PCT/EP2014/054786 patent/WO2014140073A1/en active Application Filing
- 2014-03-12 EP EP18173513.5A patent/EP3404032A3/en active Pending
- 2014-03-12 SG SG11201507394RA patent/SG11201507394RA/en unknown
- 2014-03-12 CA CA3005103A patent/CA3005103A1/en not_active Abandoned
- 2014-03-12 AR ARP140100904A patent/AR095365A1/es unknown
- 2014-03-12 CA CA2948763A patent/CA2948763C/en not_active Expired - Fee Related
- 2014-03-12 CN CN201810489045.8A patent/CN108929333A/zh active Pending
2015
- 2015-08-24 IL IL240793A patent/IL240793A0/en unknown
2016
- 2016-03-23 HK HK16103386.8A patent/HK1215433A1/zh unknown
- 2016-06-28 AU AU2016204432A patent/AU2016204432B2/en not_active Ceased
2017
- 2017-07-10 JP JP2017135083A patent/JP6442005B2/ja active Active
2018
- 2018-02-27 AU AU2018201393A patent/AU2018201393A1/en not_active Abandoned
- 2018-03-12 JP JP2018044050A patent/JP2018150298A/ja active Pending
- 2018-08-16 JP JP2018153231A patent/JP6663459B2/ja active Active
- 2018-11-22 JP JP2018219226A patent/JP2019089762A/ja active Pending
2020
- 2020-02-28 JP JP2020032846A patent/JP2020114814A/ja active Pending

Also Published As

Publication number	Publication date
CN108929333A (zh)	2018-12-04
EP3404032A2 (en)	2018-11-21
JP6663459B2 (ja)	2020-03-11
AU2014230812A1 (en)	2015-09-03
CN105377856B (zh)	2018-05-22
JP2019031493A (ja)	2019-02-28
EP3404032A3 (en)	2019-03-13
BR112015020716A2 (pt)	2017-07-18
MX2015011438A (es)	2016-02-03
CA2948763C (en)	2018-04-24
CA2948765A1 (en)	2014-09-18
NZ711192A (en)	2019-04-26
SG11201507394RA (en)	2015-10-29
JP2018008959A (ja)	2018-01-18
CA3005118A1 (en)	2014-09-18
KR20150119033A (ko)	2015-10-23
CA3005103A1 (en)	2014-09-18
EP3845540A1 (en)	2021-07-07
JP6363120B2 (ja)	2018-07-25
AU2016204432B2 (en)	2017-12-07
KR101821468B1 (ko)	2018-01-23
KR20180070715A (ko)	2018-06-26
JP2019089762A (ja)	2019-06-13
AR095365A1 (es)	2015-10-14
JP2020114814A (ja)	2020-07-30
US9303043B2 (en)	2016-04-05
AU2014230812B2 (en)	2016-04-07
CA3005112A1 (en)	2014-09-18
CN105377856A (zh)	2016-03-02
AU2014230812A8 (en)	2015-09-10
US20140275523A1 (en)	2014-09-18
RU2015138488A (ru)	2017-04-20
RU2018109979A (ru)	2019-02-28
WO2014140073A1 (en)	2014-09-18
RU2649976C2 (ru)	2018-04-06
CA2897618A1 (en)	2014-09-18
KR20170070270A (ko)	2017-06-21
IL240793A0 (en)	2015-10-29
JP6442005B2 (ja)	2018-12-19
JP2016512209A (ja)	2016-04-25
KR101871133B1 (ko)	2018-06-25
CA2948763A1 (en)	2014-09-18
EP2970329A1 (en)	2016-01-20
JP2018150298A (ja)	2018-09-27
AU2018201393A1 (en)	2018-03-15
SG10201706760YA (en)	2017-10-30
AU2016204432A1 (en)	2016-07-21

Publication	Publication Date	Title
GB201311910D0 (en)	2013-08-14	Novel Compounds
GB201311888D0 (en)	2013-08-14	Novel compounds
HK1215433A1 (zh)	2016-08-26	製備苯並氧氮雜䓬化合物的方法
GB201317363D0 (en)	2013-11-13	Novel compounds
HK1244272A1 (zh)	2018-08-03	製備噻吩並嘧啶化合物的方法
GB201318222D0 (en)	2013-11-27	Novel compounds
GB201314926D0 (en)	2013-10-02	Novel Compounds
IL241287A0 (en)	2015-11-30	Processes for the preparation of subfervir
GB201322512D0 (en)	2014-02-05	Novel compounds
IL245543B (en)	2019-01-31	A process for the fluorination of compounds
IL245542A0 (en)	2016-06-30	A process for the fluorination of compounds
GB201415000D0 (en)	2014-10-08	Improved process
GB201320021D0 (en)	2013-12-25	Novel Compounds
EP2970113A4 (en)	2016-11-16	NOVEL CONNECTIONS
GB201316762D0 (en)	2013-11-06	Novel compounds
GB201316764D0 (en)	2013-11-06	Novel compounds
GB201306308D0 (en)	2013-05-22	Novel process
IL244646B (en)	2019-09-26	Process for preparing 5-fluoro-1-alkyl-3-fluoroalkyl-1h-pyrazole-4-carbaldehyde
GB201307314D0 (en)	2013-05-29	Process for preparing chemical compounds
IL239993A (en)	2017-02-28	Process for the preparation of 5-fluoro-1-methyl-3-difluoromethyl-h1-ferrous-4-carbaldehyde
GB201401185D0 (en)	2014-03-12	Novel compounds
GB201321975D0 (en)	2014-01-29	Novel compounds
GB201321972D0 (en)	2014-01-29	Novel compounds
GB201321977D0 (en)	2014-01-29	Novel compounds
GB201321976D0 (en)	2014-01-29	Novel compounds