HK1142608A1 - 5-pyridinone substituted indazoles and pharmaceutical compositions thereof 5- - Google Patents
5-pyridinone substituted indazoles and pharmaceutical compositions thereof 5-Info
- Publication number
- HK1142608A1 HK1142608A1 HK10109173.8A HK10109173A HK1142608A1 HK 1142608 A1 HK1142608 A1 HK 1142608A1 HK 10109173 A HK10109173 A HK 10109173A HK 1142608 A1 HK1142608 A1 HK 1142608A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- pharmaceutical compositions
- substituted indazoles
- pyridinone substituted
- pyridinone
- indazoles
- Prior art date
Links
- ADEKJVNFIQUGRR-UHFFFAOYSA-N 4h-pyridin-3-one Chemical group O=C1CC=CN=C1 ADEKJVNFIQUGRR-UHFFFAOYSA-N 0.000 title abstract 2
- 150000002473 indoazoles Chemical class 0.000 title abstract 2
- 239000008194 pharmaceutical composition Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/08—Bridged systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Gastroenterology & Hepatology (AREA)
- Child & Adolescent Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Saccharide Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US95120107P | 2007-07-21 | 2007-07-21 | |
PCT/US2008/070535 WO2009015037A2 (en) | 2007-07-21 | 2008-07-18 | 5-pyridinone substituted indazoles |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1142608A1 true HK1142608A1 (en) | 2010-12-10 |
Family
ID=40282093
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK10109173.8A HK1142608A1 (en) | 2007-07-21 | 2010-09-24 | 5-pyridinone substituted indazoles and pharmaceutical compositions thereof 5- |
Country Status (13)
Country | Link |
---|---|
US (1) | US8273770B2 (xx) |
EP (1) | EP2176251B1 (xx) |
JP (1) | JP2010534248A (xx) |
KR (1) | KR20100044225A (xx) |
CN (1) | CN101861311A (xx) |
AT (1) | ATE544759T1 (xx) |
AU (1) | AU2008279321B2 (xx) |
BR (1) | BRPI0814772A2 (xx) |
CA (1) | CA2693377A1 (xx) |
ES (1) | ES2382982T3 (xx) |
HK (1) | HK1142608A1 (xx) |
NZ (1) | NZ582586A (xx) |
WO (1) | WO2009015037A2 (xx) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BRPI0806537A2 (pt) * | 2007-01-10 | 2014-04-22 | Albany Molecular Res Inc | Indazóis substituídos por 5-piridinona |
CN101861311A (zh) | 2007-07-21 | 2010-10-13 | 阿尔巴尼分子研究公司 | 5-吡啶酮取代的吲唑 |
NZ586120A (en) | 2008-01-11 | 2012-07-27 | Albany Molecular Res Inc | (1-azinone) -substituted pyridoindoles as mch antagonists |
WO2011003021A1 (en) | 2009-07-01 | 2011-01-06 | Albany Molecular Research, Inc. | Azinone-substituted azabicycloalkane-indole and azabicycloalkane-pyrrolo-pyridine mch-1 antagonists, methods of making, and use thereof |
WO2011003012A1 (en) | 2009-07-01 | 2011-01-06 | Albany Molecular Research, Inc. | Azinone-substituted azapolycycle mch-1 antagonists, methods of making, and use thereof |
WO2011003007A1 (en) | 2009-07-01 | 2011-01-06 | Albany Molecular Research, Inc. | Azabicycloalkane-indole and azabicycloalkane-pyrrolo-pyridine mch-1 antagonists, methods of making, and use thereof |
EP2448585B1 (en) * | 2009-07-01 | 2014-01-01 | Albany Molecular Research, Inc. | Azinone-substituted azepino[b]indole and pyrido-pyrrolo-azepine mch-1 antagonists, methods of making, and use thereof |
WO2012088124A2 (en) | 2010-12-21 | 2012-06-28 | Albany Molecular Research, Inc. | Tetrahydro-azacarboline mch-1 antagonists, methods of making, and uses thereof |
US8697700B2 (en) | 2010-12-21 | 2014-04-15 | Albany Molecular Research, Inc. | Piperazinone-substituted tetrahydro-carboline MCH-1 antagonists, methods of making, and uses thereof |
BR112014007603A2 (pt) * | 2011-09-30 | 2017-06-13 | Glaxosmithkline Llc | métodos de tratamento do câncer |
CN107011283A (zh) * | 2017-05-31 | 2017-08-04 | 湖南华腾制药有限公司 | 一种甲硫基取代苯并[d]恶唑衍生物的制备方法 |
CN111032656B (zh) * | 2017-08-22 | 2022-12-02 | 捷思英达医药技术(上海)有限公司 | 杂环化合物激酶抑制剂及其药物组合物和应用 |
CN112876463B (zh) * | 2019-02-21 | 2022-11-11 | 厦门宝太生物科技股份有限公司 | 一种制备pd-l1拮抗剂的中间体及其制备方法 |
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BRPI0806537A2 (pt) | 2007-01-10 | 2014-04-22 | Albany Molecular Res Inc | Indazóis substituídos por 5-piridinona |
BRPI0806506A2 (pt) * | 2007-01-10 | 2014-04-22 | Albany Molecular Res Inc | Indazóis substituídos por 5-furopiridinona |
CN101861311A (zh) | 2007-07-21 | 2010-10-13 | 阿尔巴尼分子研究公司 | 5-吡啶酮取代的吲唑 |
-
2008
- 2008-07-18 CN CN200880107571A patent/CN101861311A/zh active Pending
- 2008-07-18 US US12/176,144 patent/US8273770B2/en not_active Expired - Fee Related
- 2008-07-18 KR KR1020107003768A patent/KR20100044225A/ko not_active Application Discontinuation
- 2008-07-18 AU AU2008279321A patent/AU2008279321B2/en not_active Ceased
- 2008-07-18 CA CA2693377A patent/CA2693377A1/en not_active Abandoned
- 2008-07-18 EP EP08796320A patent/EP2176251B1/en not_active Not-in-force
- 2008-07-18 BR BRPI0814772-8A2A patent/BRPI0814772A2/pt not_active IP Right Cessation
- 2008-07-18 WO PCT/US2008/070535 patent/WO2009015037A2/en active Application Filing
- 2008-07-18 AT AT08796320T patent/ATE544759T1/de active
- 2008-07-18 JP JP2010518311A patent/JP2010534248A/ja active Pending
- 2008-07-18 NZ NZ582586A patent/NZ582586A/en not_active IP Right Cessation
- 2008-07-18 ES ES08796320T patent/ES2382982T3/es active Active
-
2010
- 2010-09-24 HK HK10109173.8A patent/HK1142608A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
CA2693377A1 (en) | 2009-01-29 |
US20090082359A1 (en) | 2009-03-26 |
AU2008279321A1 (en) | 2009-01-29 |
WO2009015037A3 (en) | 2009-04-30 |
JP2010534248A (ja) | 2010-11-04 |
EP2176251A2 (en) | 2010-04-21 |
AU2008279321B2 (en) | 2013-08-01 |
US8273770B2 (en) | 2012-09-25 |
KR20100044225A (ko) | 2010-04-29 |
NZ582586A (en) | 2011-12-22 |
CN101861311A (zh) | 2010-10-13 |
WO2009015037A2 (en) | 2009-01-29 |
ES2382982T3 (es) | 2012-06-15 |
ATE544759T1 (de) | 2012-02-15 |
EP2176251B1 (en) | 2012-02-08 |
BRPI0814772A2 (pt) | 2015-03-03 |
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