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HK1030545A1 - Use of parathyroide hormone consisting of aminoacid sequence 1-34 of human parathyroid hormone for reducing the risk of both vertebral and non vertebral bone fracture - Google Patents

Use of parathyroide hormone consisting of aminoacid sequence 1-34 of human parathyroid hormone for reducing the risk of both vertebral and non vertebral bone fracture

Info

Publication number
HK1030545A1
HK1030545A1 HK01101056A HK01101056A HK1030545A1 HK 1030545 A1 HK1030545 A1 HK 1030545A1 HK 01101056 A HK01101056 A HK 01101056A HK 01101056 A HK01101056 A HK 01101056A HK 1030545 A1 HK1030545 A1 HK 1030545A1
Authority
HK
Hong Kong
Prior art keywords
vertebral
hormone
parathyroide
risk
reducing
Prior art date
Application number
HK01101056A
Other languages
English (en)
Inventor
Janet M Hock
Gregory A Gaich
Willard H Dere
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26792729&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1030545(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of HK1030545A1 publication Critical patent/HK1030545A1/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/29Parathyroid hormone, i.e. parathormone; Parathyroid hormone-related peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/12Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/18Drugs for disorders of the endocrine system of the parathyroid hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Endocrinology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Orthopedics, Nursing, And Contraception (AREA)
  • Steroid Compounds (AREA)
  • Materials For Medical Uses (AREA)
HK01101056A 1998-08-19 2001-02-14 Use of parathyroide hormone consisting of aminoacid sequence 1-34 of human parathyroid hormone for reducing the risk of both vertebral and non vertebral bone fracture HK1030545A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US9715198P 1998-08-19 1998-08-19
US9974698P 1998-09-10 1998-09-10
PCT/US1999/018961 WO2000010596A1 (en) 1998-08-19 1999-08-19 Method of increasing bone toughness and stiffness and reducing fractures

Publications (1)

Publication Number Publication Date
HK1030545A1 true HK1030545A1 (en) 2001-05-11

Family

ID=26792729

Family Applications (3)

Application Number Title Priority Date Filing Date
HK01101056A HK1030545A1 (en) 1998-08-19 2001-02-14 Use of parathyroide hormone consisting of aminoacid sequence 1-34 of human parathyroid hormone for reducing the risk of both vertebral and non vertebral bone fracture
HK07110798.6A HK1102496A1 (en) 1998-08-19 2007-10-04 Hpth(1-34) for use in preventing or reducing the incidence or severity of vertebral and / or non vertebral fracture in a male human
HK16100519.4A HK1212602A1 (zh) 1998-08-19 2016-01-18 增加骨的韌性和硬度和減少骨折的方法

Family Applications After (2)

Application Number Title Priority Date Filing Date
HK07110798.6A HK1102496A1 (en) 1998-08-19 2007-10-04 Hpth(1-34) for use in preventing or reducing the incidence or severity of vertebral and / or non vertebral fracture in a male human
HK16100519.4A HK1212602A1 (zh) 1998-08-19 2016-01-18 增加骨的韌性和硬度和減少骨折的方法

Country Status (33)

Country Link
US (2) US6977077B1 (uk)
EP (3) EP1059933B1 (uk)
JP (5) JP2002523375A (uk)
KR (1) KR100454207B1 (uk)
CN (1) CN1205997C (uk)
AR (1) AR033639A1 (uk)
AT (1) ATE231000T1 (uk)
AU (1) AU746277B2 (uk)
BR (1) BR9909445A (uk)
CA (1) CA2325371C (uk)
CO (1) CO5130020A1 (uk)
CY (2) CY1113343T1 (uk)
CZ (1) CZ301017B6 (uk)
DE (2) DE15152726T1 (uk)
DK (4) DK1769804T3 (uk)
DZ (1) DZ2873A1 (uk)
EA (1) EA003362B1 (uk)
ES (4) ES2393200T3 (uk)
HK (3) HK1030545A1 (uk)
HR (1) HRP20000755A2 (uk)
HU (2) HU1200430D0 (uk)
ID (1) ID29039A (uk)
IL (2) IL138829A0 (uk)
MY (1) MY129227A (uk)
NO (2) NO323984B1 (uk)
NZ (1) NZ507056A (uk)
PE (1) PE20001089A1 (uk)
PL (1) PL201688B1 (uk)
PT (4) PT2907522T (uk)
TR (1) TR200003455T2 (uk)
TW (1) TW576747B (uk)
UA (1) UA72205C2 (uk)
WO (1) WO2000010596A1 (uk)

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US6770623B1 (en) * 1997-12-09 2004-08-03 Eli Lilly And Company Stabilized teriparatide solutions
DZ2873A1 (fr) * 1998-08-19 2003-12-15 Lilly Co Eli Procédé pour augmenter la dureté et la rigidité osseuse.
US20040033950A1 (en) * 2000-09-26 2004-02-19 Hock Janet M. Method of increasing bone toughness and stiffness and reducing fractures
EP1222465A1 (en) * 1999-09-20 2002-07-17 Eli Lilly And Company Method for monitoring treatment with a parathyroid hormone
US7247609B2 (en) 2001-12-18 2007-07-24 Universitat Zurich Growth factor modified protein matrices for tissue engineering
EP1531855A4 (en) * 2002-01-10 2009-07-22 Osteotrophin Llc TREATMENT OF BONE DISEASES WITH SKELETTAL ANABOLIKA
US8088734B2 (en) 2003-01-21 2012-01-03 Unigene Laboratories Inc. Oral delivery of peptides
CA2539357A1 (en) * 2003-09-19 2005-03-31 Pfizer Products Inc. Pharmaceutical compositions and methods comprising combinations of 2-alkylidene-19-nor-vitamin d derivatives and parathyroid hormone
US20060052305A1 (en) * 2004-05-10 2006-03-09 Nastech Pharmaceutical Company Inc. Method of treating osteoporosis using intranasal parathyroid hormone
US20060189533A1 (en) * 2004-05-10 2006-08-24 Nastech Pharmaceutical Company Inc. Stable pharmaceutical dosage forms of teriparatide
US20060127320A1 (en) * 2004-05-10 2006-06-15 Nastech Pharmaceutical Company Inc. Method of delivering parathyroid hormone to a human
CN101151048A (zh) * 2004-05-10 2008-03-26 纳斯泰克制药公司 增强甲状旁腺激素粘膜递送的组合物和方法
CA2566032A1 (en) 2004-05-13 2005-12-01 Alza Corporation Apparatus and method for transdermal delivery of parathyroid hormone agents
US7648965B2 (en) 2004-05-14 2010-01-19 Unigene Laboratories Inc. Method for fostering bone formation and preservation
WO2006124062A1 (en) * 2005-05-11 2006-11-23 Unigene Laboratories, Inc. Method for fostering bone formation and preservation
US20060069021A1 (en) * 2004-08-13 2006-03-30 Nastech Pharmaceutical Company Inc. Compositions and methods for intranasal administration of inactive analogs of PTH or inactivated preparations of PTH or PTH analogs
US8575101B2 (en) 2005-01-06 2013-11-05 Kuros Biosurgery Ag Supplemented matrices for the repair of bone fractures
WO2006073711A2 (en) * 2005-01-06 2006-07-13 Kuros Biosurgery Ag Use of a matrix comprising a contrast agent in soft tissues
US20070173447A1 (en) * 2005-10-25 2007-07-26 Nastech Pharmaceutical Company Inc. Method for treating osteoporosis by intranasal delivery of teriparatide with an anti-resorptive agent
WO2007059470A2 (en) * 2005-11-10 2007-05-24 Board Of Control Of Michigan Technological University Black bear parathyroid hormone and methods of using black bear parathyroid hormone
US20080051332A1 (en) * 2005-11-18 2008-02-28 Nastech Pharmaceutical Company Inc. Method of modulating hematopoietic stem cells and treating hematologic diseases using intranasal parathyroid hormone
US20080119408A1 (en) * 2006-07-07 2008-05-22 Nastech Pharmaceutical Company Inc. Pth formulations for intranasal delivery
EP1961765A1 (en) * 2006-12-08 2008-08-27 Zealand Pharma A/S Truncated PTH peptides with a cyclic conformation
WO2008125655A1 (en) 2007-04-13 2008-10-23 Kuros Biosurgery Ag Polymeric tissue sealant
US20110137243A1 (en) * 2007-09-06 2011-06-09 Abbott Cardiovascular Systems Inc. Coating On A Balloon Device
WO2009072119A2 (en) * 2007-12-04 2009-06-11 Ben-Gurion University Of The Negev Research And Development Authority Amphiphilic peptide matrices for treatment of osteoporosis
WO2009083544A2 (en) 2007-12-28 2009-07-09 Kuros Biosurgery Ag Pdgf fusion proteins incorporated into fibrin foams
MX335951B (es) 2009-09-09 2016-01-04 Asahi Kasei Pharma Corp Agente terapeutico/profilactico que contiene pth para la osteoporosis, caracterizado porque la pth se administra una vez a la semana en una dosis unitaria de 100 a 200 unidades.
AU2009356227A1 (en) 2009-12-07 2012-06-21 Michigan Technological University Black bear parathyroid hormone and methods of using black bear parathyroid hormone
US9295663B2 (en) 2010-07-14 2016-03-29 Abbott Cardiovascular Systems Inc. Drug coated balloon with in-situ formed drug containing microspheres
WO2012111852A1 (ja) * 2011-02-17 2012-08-23 帝人ファーマ株式会社 椎体骨折治療剤及びその評価方法
WO2012123028A1 (en) 2011-03-16 2012-09-20 Kuros Biosurgery Ag Pharmaceutical formulation for use in spinal fusion
KR101787956B1 (ko) 2011-06-07 2017-10-18 아사히 가세이 파마 가부시키가이샤 고순도 pth 함유 동결 건조 제제 및 그의 제조 방법
US9700485B2 (en) 2013-04-24 2017-07-11 Corning Incorporated Delamination resistant pharmaceutical glass containers containing active pharmaceutical ingredients
JP6815407B2 (ja) 2016-02-01 2021-01-20 イーライ リリー アンド カンパニー 副甲状腺ホルモン−抗rankl抗体融合化合物
JP2020506926A (ja) * 2017-02-01 2020-03-05 ザ・ジョンズ・ホプキンス・ユニバーシティ 副甲状腺ホルモンと変性椎間板疾患の再生
CN110996988A (zh) * 2017-09-22 2020-04-10 旭化成制药株式会社 稳定性优异的含有特立帕肽的液态药物组合物
CN111447943A (zh) 2018-10-29 2020-07-24 旭化成制药株式会社 以按每周2次的频率给予特立帕肽或其盐为特征的骨质疏松症的预防或治疗方法
EP4010360A1 (en) 2019-08-09 2022-06-15 Flagship Pioneering Innovations VI, LLC Modulators of parathyroid hormone receptor (pthr1)
GB2590692A (en) * 2019-12-24 2021-07-07 Corthotec Ltd Composition for improved bone fracture healing

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US4086196A (en) 1975-03-28 1978-04-25 Armour Pharmaceutical Company Parathyroid hormone
IL78342A (en) 1985-04-04 1991-06-10 Gen Hospital Corp Pharmaceutical composition for treatment of osteoporosis in humans comprising a parathyroid hormone or a fragment thereof
DE3935738A1 (de) 1989-10-27 1991-05-08 Forssmann Wolf Georg Arzneimittel, enthaltend das humane parathormon-fragment (1-37) als aktiven wirkstoff
US5208041A (en) 1991-05-23 1993-05-04 Allelix Biopharmaceuticals Inc. Essentially pure human parathyroid hormone
CA2126299C (en) 1994-06-20 2000-12-12 Gordon E. Willick Parathyroid hormone analogues for the treatment of osteoporosis
JPH0873376A (ja) 1994-09-07 1996-03-19 Asahi Chem Ind Co Ltd 骨粗鬆症治療薬
AU4472896A (en) * 1994-12-19 1996-07-10 Beth Israel Hospital Association, The Continuous low-dose administration of parathyroid hormone or its agonist
US5747456A (en) * 1994-12-19 1998-05-05 Beth Israel Deaconess Medical Center Continuous low-dose administration of parathyroid hormone or its agonist
EE9700136A (et) * 1994-12-22 1997-12-15 Astra Aktiebolag Paratüroidhormooni PTH sisaldav ravimpreparaat inhaleerimiseks
JPH08310965A (ja) * 1995-05-16 1996-11-26 Chugai Pharmaceut Co Ltd 骨癒合促進剤
ZA988030B (en) * 1997-09-09 1999-03-09 Hoffmann La Roche Fracture healing using pthrp analogs
MY120063A (en) 1997-12-09 2005-08-30 Lilly Co Eli Stabilized teriparatide solutions
DZ2873A1 (fr) 1998-08-19 2003-12-15 Lilly Co Eli Procédé pour augmenter la dureté et la rigidité osseuse.
US20040033950A1 (en) 2000-09-26 2004-02-19 Hock Janet M. Method of increasing bone toughness and stiffness and reducing fractures
US6907597B1 (en) 2000-10-13 2005-06-14 Ati International Srl Method and apparatus for constructing an executable program in memory
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Also Published As

Publication number Publication date
NO20005947D0 (no) 2000-11-24
AU746277B2 (en) 2002-04-18
ES2393200T3 (es) 2012-12-19
EP2907522B1 (en) 2017-08-02
ES2190244T3 (es) 2003-07-16
HU230697B1 (hu) 2017-09-28
HUP0101594A2 (hu) 2001-11-28
ID29039A (id) 2001-07-26
DK2907522T3 (en) 2017-10-23
TW576747B (en) 2004-02-21
DK1059933T3 (da) 2003-04-07
CN1205997C (zh) 2005-06-15
PL201688B1 (pl) 2009-04-30
DK1769804T3 (da) 2012-10-15
PT2907522T (pt) 2017-10-23
NO20005947L (no) 2000-11-24
PL343595A1 (en) 2001-08-27
DE15152726T1 (de) 2015-12-10
IL138829A0 (en) 2001-10-31
DZ2873A1 (fr) 2003-12-15
US6977077B1 (en) 2005-12-20
CZ20004134A3 (cs) 2001-08-15
CO5130020A1 (es) 2002-02-27
JP2002523375A (ja) 2002-07-30
DE69904918T2 (de) 2003-11-13
EA003362B1 (ru) 2003-04-24
HUP0101594A3 (en) 2002-01-28
KR20010072763A (ko) 2001-07-31
PT1059933E (pt) 2003-06-30
DE69904918D1 (de) 2003-02-20
CN1308545A (zh) 2001-08-15
JP2015028065A (ja) 2015-02-12
TR200003455T2 (tr) 2001-06-21
JP2014139220A (ja) 2014-07-31
US7163684B2 (en) 2007-01-16
EP1059933B1 (en) 2003-01-15
ES2549551T3 (es) 2017-11-27
HU1200430D0 (hu) 2001-11-28
UA72205C2 (uk) 2005-02-15
NO20072983L (no) 2000-11-24
JP2011021035A (ja) 2011-02-03
ATE231000T1 (de) 2003-02-15
EP1059933A1 (en) 2000-12-20
PT2266598T (pt) 2017-05-02
DK2266598T3 (en) 2017-05-15
MY129227A (en) 2007-03-30
JP2017190332A (ja) 2017-10-19
CY1119552T1 (el) 2018-03-07
AU5575099A (en) 2000-03-14
CA2325371C (en) 2004-08-17
US20050197294A1 (en) 2005-09-08
EP2907522A1 (en) 2015-08-19
HRP20000755A2 (en) 2001-02-28
EA200001015A1 (ru) 2001-02-26
HK1212602A1 (zh) 2016-06-17
IL138829A (en) 2011-01-31
PT1769804E (pt) 2012-11-13
KR100454207B1 (ko) 2004-10-26
AR033639A1 (es) 2004-01-07
NZ507056A (en) 2003-10-31
HK1102496A1 (en) 2007-11-23
CA2325371A1 (en) 2000-03-02
WO2000010596A1 (en) 2000-03-02
CZ301017B6 (cs) 2009-10-14
ES2549551T1 (es) 2015-10-29
PE20001089A1 (es) 2000-11-04
EP2266598B1 (en) 2017-02-22
DK2907522T1 (da) 2015-10-19
JP6177718B2 (ja) 2017-08-09
CY1113343T1 (el) 2016-06-22
NO323984B1 (no) 2007-07-30
BR9909445A (pt) 2000-12-12
ES2621653T3 (es) 2017-07-04
EP2266598A1 (en) 2010-12-29

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