GT200600368A - Derivados de 5-piridinil-1-azabiciclo[3.2.1]octano, su preparación y su aplicación en terapeutica - Google Patents
Derivados de 5-piridinil-1-azabiciclo[3.2.1]octano, su preparación y su aplicación en terapeuticaInfo
- Publication number
- GT200600368A GT200600368A GT200600368A GT200600368A GT200600368A GT 200600368 A GT200600368 A GT 200600368A GT 200600368 A GT200600368 A GT 200600368A GT 200600368 A GT200600368 A GT 200600368A GT 200600368 A GT200600368 A GT 200600368A
- Authority
- GT
- Guatemala
- Prior art keywords
- therapeutics
- piridinil
- azabiciclo
- octano
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/18—Bridged systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Addiction (AREA)
- Psychiatry (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Psychology (AREA)
- Vascular Medicine (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Dermatology (AREA)
- Epidemiology (AREA)
- Urology & Nephrology (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Abstract
LA INVENCIÓN SE REFIERE A LOS COMPUESTOS DE FÓRMULA GENERAL I, EN LA QUE R REPRESENTA UN GRUPO ELEGIDO ENTRE PIRAZOLILO, IMIDAZOLILO, TRIAZOLILO, OXAZOLILO, AXADIAZOLILO, TIAZOLILO, ISOTIAZOLILO, TIADIAZOLILO O TETRAZOLILO, PUDIENDO ESTAR ESTE GRUPO SUSTITUIDO OPCIONALMENTE CON UNO O VARIOS GRUPOS ELEGIDOS ENTRE ÁTOMOS DE HALÓGENOS, GURPOS ALQUILO (C1-C6), ALCOXI (C1-C6), TRIFLUOROMETOXI, TRIFLUOROMETILO, NITRO, CIANO, HIDROXI, AMINO, ALQUILAMINO (C1-C6) O DIALQUILAMINO (C1-C6); EL ENLACE CARBONO-CARBONO ENTRE LAS POSICIONES 3 Y 4 DEL CICLO AZABICICLOOCTANO ES SENCILLO O DOBLE; EN FORMA DE BASE O DE SAL DE ADICIÓN DE ÁCIDO, ASÍ COMO EN FORMA DE HIDRATO O DE SOLVATO. TAMBIÉN SE REFIERA A SU PROCESO DE PREPARACIÓN Y A SU APLICACIÓN TERAPÉUTICA. DICHOS COMPUESTOS PRESENTAN UNA BUENA AFINIDAD POR LOS RECEPTORES NICOTÍNICOS Y UNA BUENA SELECTIVIDAD FRENTE A LOS RECEPTORES NICOTÍNICOS QUE CONTIENE LA SUBUNIDAD ALFA-7.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0508528A FR2889701B1 (fr) | 2005-08-12 | 2005-08-12 | Derives de 5-pyridinyl-1-azabicyclo[3.2.1]octane, leur preparation en therapeutique. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GT200600368A true GT200600368A (es) | 2007-07-06 |
Family
ID=36273387
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GT200600368A GT200600368A (es) | 2005-08-12 | 2006-08-10 | Derivados de 5-piridinil-1-azabiciclo[3.2.1]octano, su preparación y su aplicación en terapeutica |
Country Status (41)
| Country | Link |
|---|---|
| US (2) | US7863290B2 (es) |
| EP (1) | EP1915375B1 (es) |
| JP (1) | JP5164841B2 (es) |
| KR (1) | KR101299339B1 (es) |
| CN (1) | CN101238125B (es) |
| AT (1) | ATE444964T1 (es) |
| AU (1) | AU2006281341B2 (es) |
| BR (1) | BRPI0614623A2 (es) |
| CA (1) | CA2617828C (es) |
| CR (1) | CR9625A (es) |
| CY (1) | CY1109717T1 (es) |
| DE (1) | DE602006009668D1 (es) |
| DK (1) | DK1915375T3 (es) |
| DO (1) | DOP2006000180A (es) |
| EA (1) | EA014023B1 (es) |
| EC (1) | ECSP088170A (es) |
| ES (1) | ES2332472T3 (es) |
| FR (1) | FR2889701B1 (es) |
| GT (1) | GT200600368A (es) |
| HK (1) | HK1120788A1 (es) |
| HN (1) | HN2008000090A (es) |
| HR (1) | HRP20090677T1 (es) |
| IL (1) | IL188796A (es) |
| JO (1) | JO2583B1 (es) |
| MA (1) | MA30200B1 (es) |
| ME (1) | ME01750B (es) |
| MX (1) | MX2008001968A (es) |
| MY (1) | MY147846A (es) |
| NO (1) | NO20081151L (es) |
| NZ (1) | NZ565149A (es) |
| PE (1) | PE20070339A1 (es) |
| PL (1) | PL1915375T3 (es) |
| PT (1) | PT1915375E (es) |
| RS (1) | RS51068B (es) |
| SI (1) | SI1915375T1 (es) |
| TN (1) | TNSN07472A1 (es) |
| TW (1) | TWI324158B (es) |
| UA (1) | UA92917C2 (es) |
| UY (1) | UY29744A1 (es) |
| WO (1) | WO2007020344A1 (es) |
| ZA (1) | ZA200800958B (es) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2912404B1 (fr) | 2007-02-09 | 2009-04-10 | Sanofi Aventis Sa | Derives d'azabicycloalkane,leur preparation et leur application en therapeutique. |
| GB0817424D0 (en) | 2008-09-24 | 2008-10-29 | Medivir Ab | Protease inhibitors |
| JP2017114765A (ja) * | 2014-04-25 | 2017-06-29 | 大正製薬株式会社 | トリアゾリルで置換されたヘテロアリール化合物 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5817679A (en) * | 1993-04-01 | 1998-10-06 | University Of Virginia | 7-Azabicyclo 2.2.1!-heptane and -heptene derivatives as cholinergic receptor ligands |
| EP0664293A1 (en) * | 1993-12-24 | 1995-07-26 | Duphar International Research B.V | 2-Phenyl-7-azabicycloheptanes and 6-phenyl-8-azabicyclo |
| DK0984965T3 (da) * | 1997-05-30 | 2004-09-27 | Neurosearch As | 8-azabicyclo[3.2.1]oct-2-enderivater som cholinerge ligander ved nikotin-ACh-receptorer |
| FR2834511B1 (fr) * | 2002-01-07 | 2004-02-13 | Sanofi Synthelabo | Derives de 5-(pyridin-3-yl)-1-azabicyclo[3.2.1]octane, leur preparation et leur application en therapeutique |
-
2005
- 2005-08-12 FR FR0508528A patent/FR2889701B1/fr active Active
-
2006
- 2006-07-08 UA UAA200802988A patent/UA92917C2/uk unknown
- 2006-07-26 JO JO2006252A patent/JO2583B1/en active
- 2006-08-02 DO DO2006000180A patent/DOP2006000180A/es unknown
- 2006-08-07 KR KR1020087003271A patent/KR101299339B1/ko not_active Expired - Fee Related
- 2006-08-07 EP EP06794298A patent/EP1915375B1/fr active Active
- 2006-08-07 BR BRPI0614623-6A patent/BRPI0614623A2/pt not_active IP Right Cessation
- 2006-08-07 ZA ZA200800958A patent/ZA200800958B/xx unknown
- 2006-08-07 PT PT06794298T patent/PT1915375E/pt unknown
- 2006-08-07 AU AU2006281341A patent/AU2006281341B2/en not_active Ceased
- 2006-08-07 WO PCT/FR2006/001912 patent/WO2007020344A1/fr active Application Filing
- 2006-08-07 EA EA200800575A patent/EA014023B1/ru not_active IP Right Cessation
- 2006-08-07 SI SI200630515T patent/SI1915375T1/sl unknown
- 2006-08-07 NZ NZ565149A patent/NZ565149A/en not_active IP Right Cessation
- 2006-08-07 JP JP2008525599A patent/JP5164841B2/ja not_active Expired - Fee Related
- 2006-08-07 PL PL06794298T patent/PL1915375T3/pl unknown
- 2006-08-07 DE DE602006009668T patent/DE602006009668D1/de active Active
- 2006-08-07 ES ES06794298T patent/ES2332472T3/es active Active
- 2006-08-07 MX MX2008001968A patent/MX2008001968A/es active IP Right Grant
- 2006-08-07 CA CA2617828A patent/CA2617828C/fr not_active Expired - Fee Related
- 2006-08-07 CN CN2006800291833A patent/CN101238125B/zh not_active Expired - Fee Related
- 2006-08-07 DK DK06794298.7T patent/DK1915375T3/da active
- 2006-08-07 ME MEP-2009-576A patent/ME01750B/me unknown
- 2006-08-07 RS RSP-2009/0576A patent/RS51068B/sr unknown
- 2006-08-07 AT AT06794298T patent/ATE444964T1/de active
- 2006-08-10 GT GT200600368A patent/GT200600368A/es unknown
- 2006-08-10 PE PE2006000974A patent/PE20070339A1/es not_active Application Discontinuation
- 2006-08-10 MY MYPI20063888A patent/MY147846A/en unknown
- 2006-08-11 UY UY29744A patent/UY29744A1/es not_active Application Discontinuation
- 2006-08-11 TW TW095129651A patent/TWI324158B/zh not_active IP Right Cessation
-
2007
- 2007-12-14 TN TNP2007000472A patent/TNSN07472A1/en unknown
- 2007-12-20 CR CR9625A patent/CR9625A/es unknown
-
2008
- 2008-01-15 IL IL188796A patent/IL188796A/en not_active IP Right Cessation
- 2008-01-22 HN HN2008000090A patent/HN2008000090A/es unknown
- 2008-02-11 EC EC2008008170A patent/ECSP088170A/es unknown
- 2008-02-11 US US12/028,999 patent/US7863290B2/en not_active Expired - Fee Related
- 2008-03-04 NO NO20081151A patent/NO20081151L/no not_active Application Discontinuation
- 2008-03-07 MA MA30724A patent/MA30200B1/fr unknown
- 2008-11-11 HK HK08112365.4A patent/HK1120788A1/xx not_active IP Right Cessation
-
2009
- 2009-12-17 HR HR20090677T patent/HRP20090677T1/hr unknown
-
2010
- 2010-01-05 CY CY20101100013T patent/CY1109717T1/el unknown
- 2010-11-29 US US12/955,389 patent/US8541440B2/en not_active Expired - Fee Related
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| UY29857A1 (es) | Derivados de la 4-amino-quinazolina, su preparación y su aplicación en terapéutica. | |
| EA200970149A1 (ru) | Производные n-(аминогетероарил)-1h-индол-2-карбоксамидов, их получение и их применение в терапии | |
| ZA200609634B (en) | Quinazolinone derivatives useful as vanilloid antagonists | |
| WO2004096134A3 (en) | Substituted 1,4-diazepines and uses thereof | |
| MX2009007713A (es) | Derivados de piridazina, procedimientos para su preparacion y su uso como fungicidas. | |
| UA99485C2 (ru) | Хиназолиндионовые производные, их получение и их применение в терапии | |
| ECSP067111A (es) | Derivados de pirido-pirimidina, su preparación, su aplicación en terapéutica | |
| UY29859A1 (es) | Derivados de 1-amino-isiquinolina,su preparación y su aplicación terapéutica | |
| RS20060239A (en) | Arylalkylcarbamate derivatives, preparation method thereof and use of same in therapeutics | |
| WO2008003855A3 (fr) | Utilisation de 2-benzoyl-imidazopyridines en thérapeutique | |
| ECSP088170A (es) | Derivados de 5-piridinil-1-azabiciclo[3.2.1]octano, su preparación y su aplicación en terapéutica | |
| MY146622A (en) | N-phenylpyrazole derivatives as pesticides | |
| WO2006051314A8 (en) | Guanidine derivatives as inhibitors of ddah | |
| WO2006023586A3 (en) | Guanylhydrazone compounds, compositions, methods of making and using | |
| WO2004108094A3 (en) | Sulfonamide-substituted chalcone derivatives and their use to treat diseases | |
| MY144456A (en) | Pesticidal agents on the basis of 1-aryl-aminopyrrol | |
| TW200615259A (en) | Pesticidal agents | |
| UY29858A1 (es) | Derivados de la 1-amino-ftalazina sustituida, su preparación y su aplicación en terapéutica | |
| TH91111B (th) | สารประกอบจำลองไลซีดัดแปร | |
| WO2010067008A3 (fr) | Derives bicycliques de morphine-6-glucuronide, leur preparation et leur application en therapeutique |