GB755446A - Improvements in or relating to heterocyclic compounds - Google Patents
Improvements in or relating to heterocyclic compoundsInfo
- Publication number
- GB755446A GB755446A GB746554A GB746554A GB755446A GB 755446 A GB755446 A GB 755446A GB 746554 A GB746554 A GB 746554A GB 746554 A GB746554 A GB 746554A GB 755446 A GB755446 A GB 755446A
- Authority
- GB
- United Kingdom
- Prior art keywords
- methyl
- amino
- benzofluorene
- aza
- tetra
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/14—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
The invention comprises compounds of the general formula <FORM:0755446/IV(a)/1> wherein R is an alkyl or aralkyl group and R1 and R2 are the same or different and are each hydrogen, halogen or alkoxy, and salts and quaternary salts thereof; and their preparation by condensation of 2,6-diamino-3-nitroso-pyridine with a suitably substituted O-acyl indoxyl in solution or suspension in a solvent in an inert atmosphere in the presence of an acid binding condensing agent such as sodium carbonate, sodium bicarbonate, a sodium alkoxide or piperidine followed if desired by treatment with an acid or quaternizing agent. Examples describe the preparation of (1) compounds of the above general formula in which R1 and R2 are hydrogen and R is methyl, ethyl, propyl, amyl and benzyl; and the methosulphate, hydrochloride and acetate of the compound in which R is methyl; (2) 31 - amino - 6 - bromo - 9 - methyl-1,4,9,41 - tetra - aza - 2,3 - 61, 51 - benzofluorene, the corresponding 6-chloro compound and its ethane sulphonate, (3) 31-amino-6,7-dimethoxy-9 - methyl - 1,4,9,41 - tetra - aza - 2,3 - 61, 51-benzofluorene; and (4) 31-amino-6,8-dichloro-9 - methyl - 1,4,9,41 - tetra - aza - 2,3 - 61, 51-benzofluorene. According to the Provisional Specification, R1 and R2 in the general formula above may additionally represent nitro or amino groups.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB746554A GB755446A (en) | 1954-03-15 | 1954-03-15 | Improvements in or relating to heterocyclic compounds |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB746554A GB755446A (en) | 1954-03-15 | 1954-03-15 | Improvements in or relating to heterocyclic compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB755446A true GB755446A (en) | 1956-08-22 |
Family
ID=9833608
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB746554A Expired GB755446A (en) | 1954-03-15 | 1954-03-15 | Improvements in or relating to heterocyclic compounds |
Country Status (1)
| Country | Link |
|---|---|
| GB (1) | GB755446A (en) |
-
1954
- 1954-03-15 GB GB746554A patent/GB755446A/en not_active Expired
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