GB455018A - Process for the manufacture of esters of polycyclic alcohols - Google Patents
Process for the manufacture of esters of polycyclic alcoholsInfo
- Publication number
- GB455018A GB455018A GB825436A GB825436A GB455018A GB 455018 A GB455018 A GB 455018A GB 825436 A GB825436 A GB 825436A GB 825436 A GB825436 A GB 825436A GB 455018 A GB455018 A GB 455018A
- Authority
- GB
- United Kingdom
- Prior art keywords
- esters
- dehydroandrosterone
- hydrogenated
- polycyclic alcohols
- cholanone
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J75/00—Processes for the preparation of steroids in general
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
Abstract
The process described in the parent Specification which comprises the manufacture of esters of polycyclic alcohols by subjecting esters of the male sex hormone and rosterone C19H30O0 to the action of reducing agents to convert the keto group at position 17 into a secondary alcohol group, is applied to esters of saturated or unsaturated polycyclic alcohols similarly constituted to the male sex hormone. In the case of unsaturated compounds such as dehydroandrosterone, the double bond in the nucleus becomes saturated. In examples: (1) Dehydroandrosterone monopropionate is hydrogenated in the presence of a platinum oxide catalyst using anhydrous propionic acid as the solvent to yield a mixture of isomeric monopropionates of androstandiol; (2) Dehydroandrosterone benzoate is hydrogenated in the presence of a nickel catalyst obtained by the method of Raney, the solvent being methyl cyclohexane, and the product being androstandiol; (3) The acetate of hydroxyetio-allo-cholanone-(17) is hydrogenated by being dissolved in alcohol and treated with sodium amalgam, the solution being kept just acid by the gradual addition of acetic acid. The product consists of a monoacetate of 3:17-dihydroxy-etio-allo-cholanone. Specification 443,463 is referred to.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB825436A GB455018A (en) | 1935-04-08 | 1935-04-08 | Process for the manufacture of esters of polycyclic alcohols |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB825436A GB455018A (en) | 1935-04-08 | 1935-04-08 | Process for the manufacture of esters of polycyclic alcohols |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB455018A true GB455018A (en) | 1936-10-08 |
Family
ID=9848969
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB825436A Expired GB455018A (en) | 1935-04-08 | 1935-04-08 | Process for the manufacture of esters of polycyclic alcohols |
Country Status (1)
| Country | Link |
|---|---|
| GB (1) | GB455018A (en) |
-
1935
- 1935-04-08 GB GB825436A patent/GB455018A/en not_active Expired
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| GB455018A (en) | Process for the manufacture of esters of polycyclic alcohols | |
| US2239012A (en) | Compounds of the cyclopentanopoly-hydrophenanthrene series and process of making same | |
| DE892443C (en) | Process for the preparation of ª‡-haloacrylic acid esters | |
| GB418723A (en) | A manufacture of primary diterpene-alcohols | |
| US2071804A (en) | Acyl octahydrofollicle hormones and their production | |
| US2086139A (en) | Method for the production of hydrogenation products of the follicle hormones | |
| DE953170C (en) | Process for the degradation of quaternary aromatic ammonium compounds to tertiary aromatic amines | |
| GB455019A (en) | Process for the manufacture of esters of polycyclic alcohols | |
| GB434390A (en) | Process for the production of therapeutically valuable saturated alcohols from germinal gland hormones | |
| GB455264A (en) | Process for the manufacture of esters of polycyclic alcohols | |
| GB494666A (en) | Process of preparing monohydric alcohols | |
| GB427561A (en) | Method for the production of hydrogenation products of the follicle hormones | |
| GB495887A (en) | Improvements relating to the production of alcohols of the cyclopentanopolyhydrophenanthrene series | |
| GB428133A (en) | The manufacture of hydrogenation products of follicle hormones | |
| GB468123A (en) | Process for the manufacture of tertiary alcohols of the cyclopentano polyhydro phenanthrene series | |
| GB454632A (en) | Process for the manufacture of esters of polycyclic alcohols | |
| GB447498A (en) | Improvements in or relating to the production of substances of hormone action | |
| GB443463A (en) | Process for the production of reduction products of the male sexual hormone and like substances | |
| GB453789A (en) | A process of synthetically preparing ª‰(10)-oxycamphor | |
| GB431313A (en) | A process for concentrating organic carboxylic acids | |
| CH181175A (en) | Process for the preparation of a derivative of 5,5-phenylethylhydantoin. | |
| GB672349A (en) | Improvements in or relating to the synthesis of alcohols | |
| GB911106A (en) | A process for the manufacture of unsaturated alcohols and acyl derivatives thereof | |
| GB483670A (en) | Process for the manufacture of hydroxy acids and unsaturated acids of the cyclopentanophenanthrene series | |
| GB429747A (en) | The manufacture of hydrogenation products of follicle hormones |