GB443463A - Process for the production of reduction products of the male sexual hormone and like substances - Google Patents
Process for the production of reduction products of the male sexual hormone and like substancesInfo
- Publication number
- GB443463A GB443463A GB5886/35A GB588635A GB443463A GB 443463 A GB443463 A GB 443463A GB 5886/35 A GB5886/35 A GB 5886/35A GB 588635 A GB588635 A GB 588635A GB 443463 A GB443463 A GB 443463A
- Authority
- GB
- United Kingdom
- Prior art keywords
- male sexual
- sexual hormone
- reduction
- formula
- action
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- E—FIXED CONSTRUCTIONS
- E04—BUILDING
- E04B—GENERAL BUILDING CONSTRUCTIONS; WALLS, e.g. PARTITIONS; ROOFS; FLOORS; CEILINGS; INSULATION OR OTHER PROTECTION OF BUILDINGS
- E04B2/00—Walls, e.g. partitions, for buildings; Wall construction with regard to insulation; Connections specially adapted to walls
- E04B2/84—Walls made by casting, pouring, or tamping in situ
- E04B2/86—Walls made by casting, pouring, or tamping in situ made in permanent forms
Landscapes
- Engineering & Computer Science (AREA)
- Architecture (AREA)
- Physics & Mathematics (AREA)
- Electromagnetism (AREA)
- Civil Engineering (AREA)
- Structural Engineering (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
The male sexual hormone together with compounds of saturated and unsaturated cyclopentanophenanthrols which contain a keto group insofar as they exhibit the action of the male sexual hormone and contain no benzene ring in the molecule are reduced to saturated alcohols. The reduction is preferably carried out in alcoholic solution by the action of sodium, or by the action of aluminium foil in the presence of water, or by catalytically activated hydrogen under elevated pressure. In all cases care must be taken that the reduction does not proceed beyond the alcohol stage to the desoxo product. The reduction products possess a physiological activity many times that of the starting materials, which may be the male sexual hormone C19H30O2, or its unsaturated derivatives of formula C19H28O2 or the materials of the formula C18H28O2 obtained according to Specification 421,681. Crude extracts of products with the activity of the male sexual hormone as are obtained from urine, body liquids, organs, and the like can also be converted by reduction into diols of essentially higher value. In examples: (1) crystalline male sexual hormone of the formula C19H30O2 is reduced by sodium in alcoholic solution to give a product of formula C19H32O2; (2) crystalline male sexual hormone is treated in cyclohexanol solution with hydrogen under pressure in the presence of a nickel catalyst. The reduction product exhibits a physiological activity of 5 times that of the parent material. Specification 346,130 also is referred to.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE443463X | 1934-02-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB443463A true GB443463A (en) | 1936-02-28 |
Family
ID=6529395
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB5886/35A Expired GB443463A (en) | 1934-02-24 | 1935-02-23 | Process for the production of reduction products of the male sexual hormone and like substances |
Country Status (1)
| Country | Link |
|---|---|
| GB (1) | GB443463A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE855557C (en) * | 1936-07-10 | 1952-11-13 | Boehringer & Soehne Gmbh | Method of making testosterone |
-
1935
- 1935-02-23 GB GB5886/35A patent/GB443463A/en not_active Expired
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE855557C (en) * | 1936-07-10 | 1952-11-13 | Boehringer & Soehne Gmbh | Method of making testosterone |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EP3131888A1 (en) | Production of 2-substituted 4-hydroxy-4-methyl-tetrahydropyrans from starting materials containing 2-alkyl-4,4-dimethyl-1,3-dioxanes | |
| CH262671A (en) | Process for the production of an antirachitic substance. | |
| GB443463A (en) | Process for the production of reduction products of the male sexual hormone and like substances | |
| GB731917A (en) | Manufacture of 2-ethyl-hexanal-(1) and 2-ethyl-hexanol-(1) | |
| DE868148C (en) | Process for the production of carboxylic acids | |
| GB566344A (en) | Polymerization of allyl type primary alcohols and products obtainable thereby | |
| US1999110A (en) | Primary diterpene-alcohol | |
| US2071804A (en) | Acyl octahydrofollicle hormones and their production | |
| AT157574B (en) | Process for the preparation of butanediol- (1.3). | |
| DE929187C (en) | Process for the production of metal- and acetal-free aldehydes and / or alcohols from crude aldehyde mixtures | |
| GB1106088A (en) | Process for the preparation of phloroglucinol | |
| GB398132A (en) | Process for the manufacture of cc-phenyl-ethyl-n-n-propyl-barbituric acid | |
| DE909938C (en) | Process for the preparation of 2-oxy-4- (ªÏ-amino-methyl) -benzoic acid | |
| DE928405C (en) | Process for the production of dialkoxyacetic acid esters | |
| GB460248A (en) | Manufacture of 2-aminoquinizarin and the substitution products thereof | |
| CH245880A (en) | Process for the preparation of a new oxyhydrophenanthrene derivative. | |
| GB376457A (en) | Manufacture of 1-meta-hydroxyphenyl-2-aminopropanol-1 | |
| GB213251A (en) | Improvements in the process for the manufacture of farnesol | |
| GB526699A (en) | Improvements in or relating to the production of sulphonated fatty materials | |
| GB902306A (en) | Production of nitrophenetoles | |
| GB494666A (en) | Process of preparing monohydric alcohols | |
| GB826281A (en) | Method of making dl-menthol | |
| GB455018A (en) | Process for the manufacture of esters of polycyclic alcohols | |
| GB1105168A (en) | Process for the conversion of acrolein and methacrolein into the corresponding unsaturated alcohols | |
| Wiggins | 242. The reaction of methyl tetramethyl glucosaccharate with sodium |