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GB403344A - Improvements in or relating to the germinal gland hormones - Google Patents

Improvements in or relating to the germinal gland hormones

Info

Publication number
GB403344A
GB403344A GB24935/33A GB2493533A GB403344A GB 403344 A GB403344 A GB 403344A GB 24935/33 A GB24935/33 A GB 24935/33A GB 2493533 A GB2493533 A GB 2493533A GB 403344 A GB403344 A GB 403344A
Authority
GB
United Kingdom
Prior art keywords
hormones
quinoline
pure
hormone
ether
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB24935/33A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Schering Kahlbaum AG
Original Assignee
Schering Kahlbaum AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Kahlbaum AG filed Critical Schering Kahlbaum AG
Publication of GB403344A publication Critical patent/GB403344A/en
Expired legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Crystallized derivatives of germinal gland hormones are prepared by forming addition compounds of the hormones with quinoline. Pure hormones may be obtained by decomposing the compounds with dilute acids. According to an example follicle hormone of the formula C18H22O2 is heated with an equal weight of quinoline and the crystal paste which forms on cooling is pressed out on porous tile. The molecular compound may be recrystallized from ether or pure alcohol. An ether solution may be extracted with dilute hydrochloric acid to remove the quinoline leaving the pure hormone in solution.ALSO:Crystallized derivatives of germinal gland hormones are prepared by combining the hormones with quinoline. Pure hormones may be obtained by decomposing the compounds with dilute acids. According to an example follicle hormone of the formula C18H22O2 is heated with an equal weight of quinoline. On cooling the whole solidifies to a crystal paste which is pressed out on porous tile. The molecular compound can be recrystallized from ether or pure alcohol. An ether solution of the compound may be extracted with dilute hydrochloric acid to remove the quinoline leaving the pure hormone in solution.
GB24935/33A 1932-09-27 1933-09-08 Improvements in or relating to the germinal gland hormones Expired GB403344A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE403344X 1932-09-27

Publications (1)

Publication Number Publication Date
GB403344A true GB403344A (en) 1933-12-21

Family

ID=6416740

Family Applications (1)

Application Number Title Priority Date Filing Date
GB24935/33A Expired GB403344A (en) 1932-09-27 1933-09-08 Improvements in or relating to the germinal gland hormones

Country Status (1)

Country Link
GB (1) GB403344A (en)

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