[go: up one dir, main page]

GB1140387A - 4,5,6,7-tetrahydro-thiazolo-[5,4-c]pyridines - Google Patents

4,5,6,7-tetrahydro-thiazolo-[5,4-c]pyridines

Info

Publication number
GB1140387A
GB1140387A GB31938/66A GB3193866A GB1140387A GB 1140387 A GB1140387 A GB 1140387A GB 31938/66 A GB31938/66 A GB 31938/66A GB 3193866 A GB3193866 A GB 3193866A GB 1140387 A GB1140387 A GB 1140387A
Authority
GB
United Kingdom
Prior art keywords
alkenyl
aryl
alkyl
cycloalkyl
aralkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB31938/66A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Pharma GmbH and Co KG
Original Assignee
Dr Karl Thomae GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dr Karl Thomae GmbH filed Critical Dr Karl Thomae GmbH
Publication of GB1140387A publication Critical patent/GB1140387A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/02—Preparation by ring-closure or hydrogenation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D211/74—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/86—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38—Nitrogen atoms
    • C07D277/44—Acylated amino or imino radicals
    • C07D277/46—Acylated amino or imino radicals by carboxylic acids, or sulfur or nitrogen analogues thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • E—FIXED CONSTRUCTIONS
    • E02—HYDRAULIC ENGINEERING; FOUNDATIONS; SOIL SHIFTING
    • E02F—DREDGING; SOIL-SHIFTING
    • E02F9/00—Component parts of dredgers or soil-shifting machines, not restricted to one of the kinds covered by groups E02F3/00 - E02F7/00
    • E02F9/20—Drives; Control devices

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Emergency Medicine (AREA)
  • Molecular Biology (AREA)
  • Mining & Mineral Resources (AREA)
  • Civil Engineering (AREA)
  • General Engineering & Computer Science (AREA)
  • Structural Engineering (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
GB31938/66A 1965-07-23 1966-07-15 4,5,6,7-tetrahydro-thiazolo-[5,4-c]pyridines Expired GB1140387A (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
DET0029055 1965-07-23
DET0032991 1967-01-16
DET0032993 1967-01-16
DET0032992 1967-01-16
DET0032990 1967-01-16
DET0032994 1967-01-16

Publications (1)

Publication Number Publication Date
GB1140387A true GB1140387A (en) 1969-01-15

Family

ID=27512321

Family Applications (1)

Application Number Title Priority Date Filing Date
GB31938/66A Expired GB1140387A (en) 1965-07-23 1966-07-15 4,5,6,7-tetrahydro-thiazolo-[5,4-c]pyridines

Country Status (7)

Country Link
BE (1) BE684415A (fr)
BR (1) BR6681517D0 (fr)
DE (1) DE1620508A1 (fr)
ES (9) ES329299A1 (fr)
FR (3) FR6013M (fr)
GB (1) GB1140387A (fr)
NL (2) NL6610324A (fr)

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2173187A (en) * 1985-03-23 1986-10-08 Erba Farmitalia Condensed 2-substituted thiazole derivatives
US4624956A (en) * 1983-12-16 1986-11-25 Farmitalia Carlo Erba Ulcer and gastric secretion inhibiting 4,5,6,7-tetrahydrothiazole[5,4-c]pyridine derivatives
US4847264A (en) * 1982-07-21 1989-07-11 Rorer Pharmaceutical Corporation Bicyclic nitrogen heterocyclic ethers and thioethers, and their pharmaceutical uses
WO2004083218A1 (fr) * 2003-03-20 2004-09-30 Actelion Pharmaceuticals Ltd Derives de guanidine et leur utilisation comme antagonistes des recepteurs du neuropeptide ff
US7291734B2 (en) 2002-11-14 2007-11-06 Novartis Ag N-sulfonylaminothiazole
US7547786B2 (en) 2003-11-12 2009-06-16 Daiichi Sankyo Company, Limited Process for producing thiazole derivative
WO2010071822A1 (fr) * 2008-12-19 2010-06-24 Schering Corporation Dérivés de pipéridine et de pipérazine et leurs méthodes d'utilisation
WO2010114971A1 (fr) * 2009-04-03 2010-10-07 Sepracor Inc. Composés utilisables pour le traitement de troubles à médiation par le récepteur métabotropique 5 au glutamate et leurs procédés d'utilisation
US8541592B2 (en) 2005-11-22 2013-09-24 Amgen Inc. Inhibitors of 11-beta-hydroxysteroid dehydrogenase type 1

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3680929D1 (de) 1985-02-06 1991-09-26 Boehringer Ingelheim Kg Verwendung des 2-amino-6-allyl-5,6,7,8-tetrahydro-4h-thiazolo(4,5-d)azepins zur herstellung eines zur behandlung der parkinsonschen erkrankung bzw. des parkinsonismus geeigneten arzneimittels.
US5060904A (en) * 1987-05-01 1991-10-29 David Hegarty Multi-positionable support stand with movable center of gravity and article holding means
DE69818094T2 (de) * 1997-12-11 2004-07-08 Biochem Pharma Inc., Laval Antivirale verbindungen
SE0001899D0 (sv) * 2000-05-22 2000-05-22 Pharmacia & Upjohn Ab New compounds
RS44304A (en) 2001-11-22 2007-06-04 Biovitrum Ab., Inhibitors of 11-beta-hydroxy steroid dehydrogenase type 1
JP6890179B2 (ja) 2016-12-02 2021-06-18 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ 二環式アミド化合物及びその使用方法
UA125448C2 (uk) 2017-07-14 2022-03-09 Ф. Хоффманн-Ля Рош Аг Біциклічні кетонові сполуки і способи їх застосування
PE20211247A1 (es) * 2017-10-31 2021-07-13 Hoffmann La Roche Sulfonas y sulfoxidos biciclicos y metodos de usos de los mismos
CN109134510A (zh) * 2018-11-13 2019-01-04 井冈山大学 制备2-氨基-5-cbz-4,5,6,7-四氢噻唑并[5，4-c]吡啶的新方法

Cited By (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4847264A (en) * 1982-07-21 1989-07-11 Rorer Pharmaceutical Corporation Bicyclic nitrogen heterocyclic ethers and thioethers, and their pharmaceutical uses
US4624956A (en) * 1983-12-16 1986-11-25 Farmitalia Carlo Erba Ulcer and gastric secretion inhibiting 4,5,6,7-tetrahydrothiazole[5,4-c]pyridine derivatives
GB2173187A (en) * 1985-03-23 1986-10-08 Erba Farmitalia Condensed 2-substituted thiazole derivatives
US7291734B2 (en) 2002-11-14 2007-11-06 Novartis Ag N-sulfonylaminothiazole
US7727979B2 (en) 2003-03-20 2010-06-01 Actelion Pharmaceuticals Ltd. Guanidine derivatives and their use as neuropeptide FF receptor antagonists
WO2004083218A1 (fr) * 2003-03-20 2004-09-30 Actelion Pharmaceuticals Ltd Derives de guanidine et leur utilisation comme antagonistes des recepteurs du neuropeptide ff
JP2006520330A (ja) * 2003-03-20 2006-09-07 アクテリオン　ファマシューティカルズ　リミテッド グアニジン誘導体および神経ペプチドｆｆ受容体拮抗物質としてのそれらの使用
US7547786B2 (en) 2003-11-12 2009-06-16 Daiichi Sankyo Company, Limited Process for producing thiazole derivative
US7678910B2 (en) 2003-11-12 2010-03-16 Daiichi Sankyo Company, Limited Process for producing 5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]Pyridine-2-carboxylic acid
US7880005B2 (en) 2003-11-12 2011-02-01 Daiichi Sankyo Company, Limited Process for producing 5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylic acid
US8058440B2 (en) 2003-11-12 2011-11-15 Daiichi Sankyo Company, Limited Process for producing 5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylic acid
US8541592B2 (en) 2005-11-22 2013-09-24 Amgen Inc. Inhibitors of 11-beta-hydroxysteroid dehydrogenase type 1
WO2010071822A1 (fr) * 2008-12-19 2010-06-24 Schering Corporation Dérivés de pipéridine et de pipérazine et leurs méthodes d'utilisation
US20110245267A1 (en) * 2008-12-19 2011-10-06 Schering Plough Corporation Piperidine and piperazine derivatives and methods of use thereof
WO2010114971A1 (fr) * 2009-04-03 2010-10-07 Sepracor Inc. Composés utilisables pour le traitement de troubles à médiation par le récepteur métabotropique 5 au glutamate et leurs procédés d'utilisation

Also Published As

Publication number Publication date
ES349321A1 (es) 1969-04-01
ES349318A1 (es) 1969-04-01
BR6681517D0 (pt) 1973-12-27
NL6610324A (fr) 1967-01-24
ES329299A1 (es) 1968-02-16
ES349317A1 (es) 1969-04-01
NL6800589A (fr) 1968-07-17
DE1620508A1 (de) 1969-09-18
FR1498465A (fr) 1967-10-20
FR6013M (fr) 1968-05-06
BE684415A (fr) 1967-01-20
ES349319A1 (es) 1969-04-01
ES349314A1 (es) 1969-04-01
FR94123E (fr) 1969-07-04
ES349316A1 (es) 1969-04-01
ES349322A1 (es) 1969-04-01
ES349320A1 (es) 1969-04-01

Similar Documents

Publication Publication Date Title
GB1140387A (en) 4,5,6,7-tetrahydro-thiazolo-[5,4-c]pyridines
FI893361A (fi) Menetelmä ACAT-inhiboivien kinoliinijohdannaisten valmistamiseksi
IE37572B1 (en) 1-aminouracil compounds a process for their production and their use as herbicides
GB1053085A (fr)
GB1340596A (en) Tetrahydrobenzothiazolyl derivatives and their use as herbicides
GB1366062A (en) 1-acyl-3-amino-sulphonyl-2-imino-benzimidazolines process for their production and their use as fungicides
GB1470544A (en) Sulphonic acid esters
IE36127L (en) 3-benzylpyridines
GB1341884A (en) Herbicidal 1,2,4-thiadiazolyl derivatives
GB1325386A (en) Quinazoline derivatives processes for producing them and compositions containing them
IE38531L (en) Production of n-chloroformyl-carbamic acid amides
GB1225699A (fr)
GB1345144A (en) Sulphobenzoic acid derivatives
GB1296371A (fr)
JPS5236684A (en) Process for preparation of novel penicillins and cephalosporins
GB1229996A (fr)
GB915806A (en) Improvements relating to various forms of synthetic polyamides
GB1361249A (en) 3-sulphoalkyl-6-hydroxy-pyrid--2--ones their manufacture and use
ES317079A1 (es) Un procedimiento para la preparaciën en penicilinas
GB1253855A (en) New heterocyclic amines and compositions containing them, their production and use
GB1205519A (en) Novel 1,2-dihydro-benztriazine derivatives and process for preparing the same
JPS52106883A (en) Novel penicillins and cephalosporins
ES2002912A6 (es) Procedimiento para la produccion de antibioticos de cefalosporina
GB1394825A (en) Lactam derivatives
GB1382974A (en) Process for the production of thiosemicarbazides