FR2645153B1 - Derives de la thieno-triazolo-diazepine ainsi que leur procede de preparation - Google Patents

Derives de la thieno-triazolo-diazepine ainsi que leur procede de preparation

Info

Publication number: FR2645153B1
Authority: FR; France
Prior art keywords: thieno; triazolo; preparation process; diazepine derivatives; diazepine
Prior art date: 1989-03-31
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Lifetime

Application number

FR909004156A

Other languages

English (en)

Other versions

FR2645153A1 (fr

Inventor

Pierre Braquet

Jean-Pierre Laurent

Andre Esanu

Alain Rolland

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Ipsen Pharma SAS

Original Assignee

Societe de Conseils de Recherches et dApplications Scientifiques SCRAS SAS

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-03-31

Filing date

1990-04-02

Publication date

1992-04-17

1990-04-02 Application filed by Societe de Conseils de Recherches et dApplications Scientifiques SCRAS SAS filed Critical Societe de Conseils de Recherches et dApplications Scientifiques SCRAS SAS

1990-10-05 Publication of FR2645153A1 publication Critical patent/FR2645153A1/fr

1992-04-17 Application granted granted Critical

1992-04-17 Publication of FR2645153B1 publication Critical patent/FR2645153B1/fr

2010-04-02 Anticipated expiration legal-status Critical

Status Expired - Lifetime legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/22—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains four or more hetero rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Pulmonology (AREA)
Hematology (AREA)
Diabetes (AREA)
Immunology (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

FR909004156A 1989-03-31 1990-04-02 Derives de la thieno-triazolo-diazepine ainsi que leur procede de preparation Expired - Lifetime FR2645153B1 (fr)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB898907256A GB8907256D0 (en)	1989-03-31	1989-03-31	New derivatives of hetrazepine as anti-asthmatic anti-allergic and gastro-intestinal protectors

Publications (2)

Publication Number	Publication Date
FR2645153A1 FR2645153A1 (fr)	1990-10-05
FR2645153B1 true FR2645153B1 (fr)	1992-04-17

Family

ID=10654231

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
FR909004155A Expired - Lifetime FR2645022B1 (fr)	1989-03-31	1990-04-02	Compositions therapeutiques a base de derives de la thieno-triazolo-diazepine
FR909004156A Expired - Lifetime FR2645153B1 (fr)	1989-03-31	1990-04-02	Derives de la thieno-triazolo-diazepine ainsi que leur procede de preparation

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
FR909004155A Expired - Lifetime FR2645022B1 (fr)	1989-03-31	1990-04-02	Compositions therapeutiques a base de derives de la thieno-triazolo-diazepine

Country Status (30)

Country	Link
US (1)	US5492906A (fr)
JP (1)	JPH07103127B2 (fr)
KR (1)	KR900014396A (fr)
AT (1)	AT394561B (fr)
AU (1)	AU622007B2 (fr)
BE (1)	BE1003699A3 (fr)
CA (1)	CA2013518C (fr)
CH (1)	CH680365A5 (fr)
DE (1)	DE4010316C2 (fr)
DK (1)	DK80890A (fr)
ES (1)	ES2019243A6 (fr)
FI (1)	FI95036C (fr)
FR (2)	FR2645022B1 (fr)
GB (2)	GB8907256D0 (fr)
GR (1)	GR1000394B (fr)
HK (1)	HK95192A (fr)
IE (1)	IE64564B1 (fr)
IN (1)	IN174015B (fr)
IT (1)	IT1240350B (fr)
LU (1)	LU87710A1 (fr)
MA (1)	MA21790A1 (fr)
MY (1)	MY105538A (fr)
NL (1)	NL194827C (fr)
NO (1)	NO173784C (fr)
NZ (1)	NZ233011A (fr)
OA (1)	OA09442A (fr)
PT (1)	PT93629B (fr)
SE (1)	SE505417C2 (fr)
TN (1)	TNSN90042A1 (fr)
ZA (1)	ZA901765B (fr)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
PH30676A (en) *	1986-07-22	1997-09-16	Boehringer Ingelhein Kg	Hetrazepine compounds which have useful pharmaceutical utility
US5221671A (en) *	1988-10-31	1993-06-22	Eisai Co., Ltd.	Triazolo-1,4-diazepine derivatives and their use in pharmaceuticals
US5304553A (en) *	1988-10-31	1994-04-19	Eisai Co., Ltd.	1,4-diazepine derivative and its pharmaceutical use
US5382579A (en) *	1988-10-31	1995-01-17	Eisai Co., Ltd.	Triazolo-1,4-diazepine derivatives and their use in pharmaceuticals
DE4027470A1 (de) *	1990-08-30	1992-03-05	Boehringer Ingelheim Kg	Neue hetrazepinoide amide
ES2061406B1 (es) *	1993-05-07	1995-06-01	Uriach & Cia Sa J	Nuevos derivados de la 2-(quinolina) con actividad farmacologica.
FI101989B1 (fi) *	1996-11-22	1998-09-30	Enso Oy	Menetelmät neste- ja kaasutiiviin pakkauskartongin sekä pakkauksen valmistamiseksi sekä menetelmien mukaisesti valmistetut tuotteet
CA2294139A1 (fr)	1997-06-25	1998-12-30	Nikken Chemicals Co., Ltd.	Composes de triazolo-1,4-diazepine et composition medicinale les contenant
FR2779652B1 (fr) *	1998-06-15	2001-06-08	Sod Conseils Rech Applic	Utilisation de diazepines pour la preparation de medicaments destines a traiter les etats pathologiques ou les maladies dans lesquels un des recepteurs de la somatostatine est implique
US6987105B2 (en) *	2000-04-28	2006-01-17	Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College	Synthesis and use of thienotriazolodiazepines
MXPA05012900A (es) *	2003-05-30	2006-02-22	Ranbaxy Lab Ltd	Derivados de pirrol sustituidos.
CA2627599A1 (fr) *	2005-11-08	2007-05-18	Ranbaxy Laboratories Limited	Procede de preparation de sel hemicalcique d'acide (3r,5r)-7-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-[(4-hydroxymethylphenylamino)carbonyl]-pyrrol-1-yl]-3,5-dihydroxy-heptanoique
CL2007000667A1 (es) *	2006-03-14	2008-03-14	Ranbaxi Lab Ltd	Composicion farmaceutica que comprende al acido 7-[2-(4-fluorofenil)-5-isopropil-3-fenil-4-[(4-hidroximetilfenilamino)carbonil]pirrol-1-il]-3,5-dihidroxi-heptanoico o una sal y al menos un agente estabilizante; procedimiento de preparacion, util en e
AR063469A1 (es) *	2006-07-14	2009-01-28	Ranbaxy Lab Ltd	Formas polimorficas de ácido (3r,5r)-7-[2-(4-fluorofenil)-5-isopropil-3-fenil-4-[(4-hidroximetilfenilamino)carbonil]-pirrol-1-il]-3, 5-dihidroxi-heptanoico, sal hemicalcio, metodos de preparacion de las mismas, una composicion farmaceutica que las comprende y su uso en el tratamiento de enfermedades
KR101675984B1 (ko) *	2015-02-23	2016-11-14	한양대학교 에리카산학협력단	티에노디아제핀 유도체 또는 이의 약학적으로 허용가능한 염, 및 이를 유효성분으로 포함하는 약학적 조성물

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
PH30676A (en) *	1986-07-22	1997-09-16	Boehringer Ingelhein Kg	Hetrazepine compounds which have useful pharmaceutical utility
EP0316456A4 (fr) *	1987-06-08	1990-05-14	Yoshitomi Pharmaceutical	Composes de thienotriazolodiazepine a substitution ether et leur utilisation en medecine.
FI95708C (fi) *	1988-10-31	1996-03-11	Eisai Co Ltd	Analogiamenetelmä 1,4-diatsepiinijohdannaisen ja sen farmaseuttisesti sopivan suolan valmistamiseksi
NL9000627A (nl) *	1990-03-29	1991-10-16	Scras	Werkwijze ter bereiding van nieuwe thienotriazolo-diazepines.

1989
- 1989-03-31 GB GB898907256A patent/GB8907256D0/en active Pending
1990
- 1990-03-07 ZA ZA901765A patent/ZA901765B/xx unknown
- 1990-03-07 NO NO901070A patent/NO173784C/no not_active IP Right Cessation
- 1990-03-07 IN IN220DE1990 patent/IN174015B/en unknown
- 1990-03-07 IE IE80690A patent/IE64564B1/en not_active IP Right Cessation
- 1990-03-08 GR GR900100165A patent/GR1000394B/el not_active IP Right Cessation
- 1990-03-09 AT AT0056790A patent/AT394561B/de not_active IP Right Cessation
- 1990-03-12 SE SE9000871A patent/SE505417C2/sv not_active IP Right Cessation
- 1990-03-19 NL NL9000626A patent/NL194827C/nl not_active IP Right Cessation
- 1990-03-21 NZ NZ233011A patent/NZ233011A/xx unknown
- 1990-03-26 JP JP2073582A patent/JPH07103127B2/ja not_active Expired - Lifetime
- 1990-03-27 BE BE9000343A patent/BE1003699A3/fr not_active IP Right Cessation
- 1990-03-29 GB GB9007000A patent/GB2229723B/en not_active Expired - Lifetime
- 1990-03-29 LU LU87710A patent/LU87710A1/fr unknown
- 1990-03-29 CH CH1044/90A patent/CH680365A5/fr not_active IP Right Cessation
- 1990-03-30 DE DE4010316A patent/DE4010316C2/de not_active Expired - Fee Related
- 1990-03-30 TN TNTNSN90042A patent/TNSN90042A1/fr unknown
- 1990-03-30 CA CA002013518A patent/CA2013518C/fr not_active Expired - Fee Related
- 1990-03-30 IT IT19884A patent/IT1240350B/it active IP Right Grant
- 1990-03-30 PT PT93629A patent/PT93629B/pt active IP Right Grant
- 1990-03-30 AU AU52425/90A patent/AU622007B2/en not_active Ceased
- 1990-03-30 DK DK080890A patent/DK80890A/da not_active Application Discontinuation
- 1990-03-30 OA OA59759A patent/OA09442A/fr unknown
- 1990-03-30 ES ES9000912A patent/ES2019243A6/es not_active Expired - Lifetime
- 1990-03-30 MY MYPI90000509A patent/MY105538A/en unknown
- 1990-03-30 KR KR1019900004522A patent/KR900014396A/ko not_active Abandoned
- 1990-03-30 MA MA22056A patent/MA21790A1/fr unknown
- 1990-03-30 FI FI901605A patent/FI95036C/fi not_active IP Right Cessation
- 1990-04-02 FR FR909004155A patent/FR2645022B1/fr not_active Expired - Lifetime
- 1990-04-02 FR FR909004156A patent/FR2645153B1/fr not_active Expired - Lifetime
1992
- 1992-02-18 US US07/837,580 patent/US5492906A/en not_active Expired - Lifetime
- 1992-11-26 HK HK951/92A patent/HK95192A/xx not_active IP Right Cessation

Also Published As

Publication number	Publication date
NO901070D0 (no)	1990-03-07
DK80890D0 (da)	1990-03-30
GB9007000D0 (en)	1990-05-30
ZA901765B (en)	1990-12-28
SE505417C2 (sv)	1997-08-25
IE64564B1 (en)	1996-08-23
HK95192A (en)	1992-12-04
AU622007B2 (en)	1992-03-26
DK80890A (da)	1990-10-01
FR2645022B1 (fr)	1992-04-17
NO901070L (no)	1990-10-01
TNSN90042A1 (fr)	1991-03-05
GR900100165A (en)	1990-07-31
GB2229723B (en)	1992-07-01
GR1000394B (el)	1992-06-30
NO173784B (no)	1993-10-25
DE4010316A1 (de)	1990-10-04
IN174015B (fr)	1994-08-27
IT1240350B (it)	1993-12-07
FI95036B (fi)	1995-08-31
LU87710A1 (fr)	1990-07-24
PT93629B (pt)	1996-07-31
MA21790A1 (fr)	1990-10-01
NL9000626A (nl)	1990-10-16
FR2645022A1 (fr)	1990-10-05
IE900806L (en)	1990-09-30
ES2019243A6 (es)	1991-06-01
ATA56790A (de)	1991-10-15
JPH02289582A (ja)	1990-11-29
FR2645153A1 (fr)	1990-10-05
IT9019884A1 (it)	1991-09-30
MY105538A (en)	1994-10-31
CA2013518C (fr)	2004-02-24
NO173784C (no)	1994-02-02
SE9000871L (sv)	1990-10-01
SE9000871D0 (sv)	1990-03-12
JPH07103127B2 (ja)	1995-11-08
US5492906A (en)	1996-02-20
NL194827C (nl)	2003-04-03
NZ233011A (en)	1991-02-26
PT93629A (pt)	1990-11-20
FI901605A0 (fi)	1990-03-30
GB8907256D0 (en)	1989-05-17
AU5242590A (en)	1990-11-01
IT9019884A0 (it)	1990-03-30
FI95036C (fi)	1995-12-11
DE4010316C2 (de)	2003-05-28
KR900014396A (ko)	1990-10-23
GB2229723A (en)	1990-10-03
AT394561B (de)	1992-05-11
CH680365A5 (fr)	1992-08-14
BE1003699A3 (fr)	1992-05-26
CA2013518A1 (fr)	1990-09-30
NL194827B (nl)	2002-12-02
OA09442A (fr)	1992-10-15

Publication	Publication Date	Title
FR2634122B1 (fr)	1993-11-19	Derives de furanne et leur procede de preparation
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FR2645153B1 (fr)	1992-04-17	Derives de la thieno-triazolo-diazepine ainsi que leur procede de preparation
MC1982A1 (fr)	1989-11-23	Procede de preparation de derives de la didesoxycitidine
FR2656324B1 (fr)	1994-09-09	Pigment azouique et son procede de preparation.
FI905748A7 (fi)	1991-05-23	Menetelmä dopamiinin ja dopamiinijohdannaisten 4-O-fosfaattien valmis tamiseksi
FR2680506B1 (fr)	1994-09-02	Procede de preparation de derives de la beta-phenylisoserine et leur utilisation.
IT1237528B (it)	1993-06-08	Composti fotocromatici e termocromatici spiro-ossazepin-ossazine e procedimento per la loro preparazione
FR2656308B1 (fr)	1994-04-01	Derives du glycerol, ainsi que leur procede de preparation.
FR2649713B1 (fr)	1991-10-18	Copolyesteramides semialiphatiques thermotropes et leur procede de preparation
FR2645154B1 (fr)	1992-04-17	Derives sulfonyles de la thieno-triazolo-diazepine ainsi que leur procede de preparation
FI900627A7 (fi)	1990-08-12	2,3,23-trihydroksiurs-12-eeni ja sen johdannaiset, menetelmiä niiden valmistamiseksi ja niiden käyttö
FR2645859B1 (fr)	1992-06-05	Derives di-substitues des n,n(prime)-ditrimethoxybenzoyle piperazines ainsi que leur procede de preparation
FI905173A7 (fi)	1991-04-24	Diatsabisykloamiiniyhdisteet ja menetelmä niiden valmistamiseksi
MC1692A1 (fr)	1986-07-18	Procede de preparation de derives de phenyltetraenyle derives de phenyltetraenyle et leur application
MA22752A1 (fr)	1993-07-01	Derives de la benzofuranylimidazole ainsi que leur procede de preparation
FI921507A7 (fi)	1992-04-06	Uudet 2-spirosyklopropyylikefalosporiinisulfonijohdannaiset ja menetel mä niiden valmistamiseksi
FR2608378B1 (fr)	1990-07-06	Miels aromatises et leur procede de preparation
FR2643902B1 (fr)	1991-10-11	Procede de preparation de n-allylmetatrifluoromethylaniline
FR2563223B1 (fr)	1988-12-16	Nouveaux derives du pyrane ainsi que leur procede de preparation
MA22013A1 (fr)	1991-07-01	Derives du (n-methyl -n-alcoyl) amino-3 methoxymethylene -2 propane 1 - ol, ainsi que leur procede de preparation .
EP0321572A4 (fr)	1989-04-24	Derives de pregnane et procede de preparation.
MA21770A1 (fr)	1990-10-01	Peptides sdk ainsi que leur procede de preparation .
MC2152A1 (fr)	1992-03-10	Procede de preparation du 10,10-dioxyde de 1-ethylphenoxathiine et ce compose ainsi prepare
FR2684102B1 (fr)	1994-03-11	Procede de preparation de polyazidoalcools ainsi que de polyaminoalcools et polyazidothiols derives de ceux-ci.

Legal Events

Date	Code	Title	Description
2010-01-22	ST	Notification of lapse	Effective date: 20091231