FR2585705B1 - Sels de cephalosporine et compositions injectables - Google Patents

Sels de cephalosporine et compositions injectables

Info

Publication number: FR2585705B1
Authority: FR; France
Prior art keywords: injectable compositions; cephalosporin salts; cephalosporin; salts; injectable
Prior art date: 1985-08-05
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

FR8610892A

Other languages

English (en)

Other versions

FR2585705A1 (fr

Inventor

Murray A Kaplan

Thomas W Hudyma

Robert A Lipper

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Bristol Myers Co

Original Assignee

Bristol Myers Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-08-05

Filing date

1986-07-28

Publication date

1989-01-13

1986-07-28 Application filed by Bristol Myers Co filed Critical Bristol Myers Co

1987-02-06 Publication of FR2585705A1 publication Critical patent/FR2585705A1/fr

1989-01-13 Application granted granted Critical

1989-01-13 Publication of FR2585705B1 publication Critical patent/FR2585705B1/fr

Status Expired legal-status Critical Current

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
- A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
- C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
- C07D501/46—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof with the 7-amino radical acylated by carboxylic acids containing hetero rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Oncology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Communicable Diseases (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Cephalosporin Compounds (AREA)
Medicinal Preparation (AREA)

FR8610892A 1985-08-05 1986-07-28 Sels de cephalosporine et compositions injectables Expired FR2585705B1 (fr)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US76223585A	1985-08-05	1985-08-05

Publications (2)

Publication Number	Publication Date
FR2585705A1 FR2585705A1 (fr)	1987-02-06
FR2585705B1 true FR2585705B1 (fr)	1989-01-13

Family

ID=25064475

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FR8610892A Expired FR2585705B1 (fr)	1985-08-05	1986-07-28	Sels de cephalosporine et compositions injectables

Country Status (34)

Country	Link
JP (1)	JPH0615548B2 (fr)
KR (1)	KR930003121B1 (fr)
AR (1)	AR243894A1 (fr)
AT (1)	AT390957B (fr)
AU (1)	AU597262B2 (fr)
BE (1)	BE905219A (fr)
CA (1)	CA1284994C (fr)
CH (1)	CH675581A5 (fr)
CS (2)	CS276717B6 (fr)
CY (1)	CY1614A (fr)
DD (2)	DD254941A5 (fr)
DE (1)	DE3626375A1 (fr)
DK (1)	DK162053C (fr)
EG (1)	EG18003A (fr)
ES (1)	ES2002112A6 (fr)
FI (1)	FI84484C (fr)
FR (1)	FR2585705B1 (fr)
GB (1)	GB2179936B (fr)
GR (1)	GR862055B (fr)
HK (1)	HK99691A (fr)
HU (1)	HU196602B (fr)
IE (1)	IE59222B1 (fr)
IL (1)	IL79608A (fr)
IT (1)	IT1197067B (fr)
LU (2)	LU86540A1 (fr)
MY (1)	MY102212A (fr)
NL (1)	NL8601991A (fr)
OA (1)	OA08672A (fr)
PT (1)	PT83134B (fr)
SE (1)	SE469633B (fr)
SG (1)	SG79791G (fr)
SU (1)	SU1516013A3 (fr)
YU (1)	YU45793B (fr)
ZA (1)	ZA865842B (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4883868A (en) *	1984-12-27	1989-11-28	Banyu Pharmaceutical Co., Ltd.	7-amino-3-(substituted isoindolinium)methyl-3-cephem derivatives
US4959469A (en) *	1984-12-27	1990-09-25	Banyu Pharmaceutical Company, Ltd.	Crystalline cephalosporin compounds
US4910301A (en) *	1985-08-05	1990-03-20	Bristol-Myers Company	Cefepime cephalosporin salts
US5244891A (en) *	1985-08-05	1993-09-14	Bristol-Myers Squibb Company	Injectable compositions of cefepime dihydrochloride hydrate
US4808617A (en) *	1985-12-18	1989-02-28	Bristol-Myers Company	Lyophilized or precipitated cephalosporin zwitterion and salt combination
KR950010084B1 (ko) *	1987-06-25	1995-09-06	반유세이야꾸 가부시끼가이샤	결정성 세팔로스포린 화합물, 그의 제조법 및 그의 제조 중간체
JPH02101081A (ja) *	1988-10-08	1990-04-12	Meiji Seika Kaisha Ltd	セファロスポリン誘導体結晶性二塩酸塩及びその製造法
CA2011116C (fr) *	1989-03-06	1999-11-16	Murray A. Kaplan	Dihydrochlorure de bmy-28142 lyophilise pour usage parenteral
CA2101571A1 (fr) *	1992-09-08	1994-03-09	Elizabeth A. Garofalo	Dihydrate cristallise d'un sel de cephalosporine dihydrate; compositions injectables a base de ce compose
EP0638573A1 (fr) *	1993-08-10	1995-02-15	Lucky Ltd.	Hydrates crystallins d'une céphalosporine et procédé pour leur préparation
US7592447B2 (en)	2003-12-23	2009-09-22	Sandoz Ag	Process for production of intermediates for use in cefalosporin synthesis
WO2008056221A2 (fr) *	2006-11-06	2008-05-15	Orchid Chemicals & Pharmaceuticals Limited	Sel de sulfate cristallin d'antibiotique céphalosporine
DE102012101680A1 (de) *	2012-02-29	2013-08-29	Aicuris Gmbh & Co. Kg	Pharmazeutische Zubereitung enthaltend ein antiviral wirksames Dihydrochinazolinderivat

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS55151588A (en) *	1979-05-14	1980-11-26	Takeda Chem Ind Ltd	Preparation of cephalosporin salt crystal
CA1213882A (fr) *	1982-03-04	1986-11-12	Jun Okumura	Cephalosporines
US4406899A (en) *	1982-03-04	1983-09-27	Bristol-Myers Company	Cephalosporins
US4525473A (en) *	1983-03-30	1985-06-25	Bristol-Myers Company	Cephalosporins
DE3419015A1 (de) *	1984-05-22	1985-11-28	Bayer Ag, 5090 Leverkusen	Verfahren zur herstellung von cephalosporinen
GB2165245B (en) *	1984-10-01	1988-05-25	Glaxo Group Ltd	Chemical compounds
GB8424692D0 (en) *	1984-10-01	1984-11-07	Glaxo Group Ltd	Chemical compounds

1986
- 1986-07-28 CA CA000514766A patent/CA1284994C/fr not_active Expired - Lifetime
- 1986-07-28 FR FR8610892A patent/FR2585705B1/fr not_active Expired
- 1986-07-29 AR AR86304717A patent/AR243894A1/es active
- 1986-07-30 AU AU60694/86A patent/AU597262B2/en not_active Expired
- 1986-07-31 YU YU137186A patent/YU45793B/sh unknown
- 1986-08-01 FI FI863155A patent/FI84484C/fi not_active IP Right Cessation
- 1986-08-01 IE IE207886A patent/IE59222B1/en not_active IP Right Cessation
- 1986-08-04 DK DK371886A patent/DK162053C/da not_active IP Right Cessation
- 1986-08-04 SU SU864027914A patent/SU1516013A3/ru active
- 1986-08-04 PT PT83134A patent/PT83134B/pt unknown
- 1986-08-04 CS CS865827A patent/CS276717B6/cs unknown
- 1986-08-04 CH CH3117/86A patent/CH675581A5/de not_active IP Right Cessation
- 1986-08-04 LU LU86540A patent/LU86540A1/fr unknown
- 1986-08-04 GB GB8618989A patent/GB2179936B/en not_active Expired
- 1986-08-04 DE DE19863626375 patent/DE3626375A1/de not_active Ceased
- 1986-08-04 NL NL8601991A patent/NL8601991A/nl not_active Application Discontinuation
- 1986-08-04 BE BE07217010A patent/BE905219A/fr not_active IP Right Cessation
- 1986-08-04 LU LU88574C patent/LU88574I2/fr unknown
- 1986-08-04 IT IT21409/86A patent/IT1197067B/it active Protection Beyond IP Right Term
- 1986-08-04 SE SE8603308A patent/SE469633B/sv not_active IP Right Cessation
- 1986-08-04 ZA ZA865842A patent/ZA865842B/xx unknown
- 1986-08-04 CS CS903570A patent/CS276849B6/cs unknown
- 1986-08-04 IL IL79608A patent/IL79608A/xx not_active IP Right Cessation
- 1986-08-04 JP JP61183288A patent/JPH0615548B2/ja not_active Expired - Lifetime
- 1986-08-04 GR GR862055A patent/GR862055B/el unknown
- 1986-08-05 ES ES8600872A patent/ES2002112A6/es not_active Expired
- 1986-08-05 DD DD86293433A patent/DD254941A5/de unknown
- 1986-08-05 KR KR1019860006445A patent/KR930003121B1/ko not_active IP Right Cessation
- 1986-08-05 HU HU863376A patent/HU196602B/hu unknown
- 1986-08-05 AT AT0211086A patent/AT390957B/de not_active IP Right Cessation
- 1986-08-05 OA OA58918A patent/OA08672A/xx unknown
1987
- 1987-09-29 MY MYPI87002279A patent/MY102212A/en unknown
1988
- 1988-03-30 DD DD88314213A patent/DD268395A5/de unknown
1989
- 1989-08-04 EG EG489/86A patent/EG18003A/xx active
1991
- 1991-10-02 SG SG797/91A patent/SG79791G/en unknown
- 1991-12-05 HK HK996/91A patent/HK99691A/xx not_active IP Right Cessation
1992
- 1992-07-10 CY CY1614A patent/CY1614A/en unknown

Also Published As

Publication number	Publication date
HK99691A (en)	1991-12-13
EG18003A (en)	1991-08-30
GR862055B (en)	1986-12-24
CS276717B6 (en)	1992-08-12
AU6069486A (en)	1987-02-12
CS276849B6 (en)	1992-08-12
IE862078L (en)	1987-02-05
IE59222B1 (en)	1994-01-26
ZA865842B (en)	1987-04-29
SE469633B (sv)	1993-08-09
YU137186A (en)	1987-12-31
PT83134B (pt)	1989-07-31
SG79791G (en)	1991-11-15
LU86540A1 (fr)	1987-03-06
ATA211086A (de)	1990-01-15
FI84484B (fi)	1991-08-30
ES2002112A6 (es)	1988-07-16
AU597262B2 (en)	1990-05-31
GB2179936B (en)	1989-04-26
KR880002530A (ko)	1988-05-09
FI863155A0 (fi)	1986-08-01
PT83134A (en)	1986-09-01
DD254941A5 (de)	1988-03-16
HU196602B (en)	1988-12-28
IT1197067B (it)	1988-11-25
DE3626375A1 (de)	1987-02-12
FI84484C (fi)	1991-12-10
IT8621409A1 (it)	1988-02-04
MY102212A (en)	1992-05-15
BE905219A (fr)	1987-02-04
IL79608A0 (en)	1986-11-30
CA1284994C (fr)	1991-06-18
AR243894A1 (es)	1993-09-30
CY1614A (en)	1992-07-10
FR2585705A1 (fr)	1987-02-06
SE8603308D0 (sv)	1986-08-04
DK162053C (da)	1992-02-10
GB2179936A (en)	1987-03-18
DK371886A (da)	1987-02-06
OA08672A (en)	1989-03-31
AT390957B (de)	1990-07-25
KR930003121B1 (ko)	1993-04-19
SE8603308L (sv)	1987-02-06
DK162053B (da)	1991-09-09
IT8621409A0 (it)	1986-08-04
SU1516013A3 (ru)	1989-10-15
FI863155A (fi)	1987-02-06
YU45793B (sh)	1992-07-20
JPS62103090A (ja)	1987-05-13
DK371886D0 (da)	1986-08-04
NL8601991A (nl)	1987-03-02
GB8618989D0 (en)	1986-09-17
JPH0615548B2 (ja)	1994-03-02
CH675581A5 (fr)	1990-10-15
DD268395A5 (de)	1989-05-31
HUT41802A (en)	1987-05-28
LU88574I2 (fr)	1995-03-01
IL79608A (en)	1991-07-18

Publication	Publication Date	Title
DK106786D0 (da)	1986-03-07	Heterocycliske forbindelser
DK521589A (da)	1989-12-18	Cyclopropyl-substituerede dialkyl-forbindelser med insekticid virkning
ZA89407B (en)	1989-09-27	Cephalosporin salts and injectable compositions
FR2585705B1 (fr)	1989-01-13	Sels de cephalosporine et compositions injectables
DK496086A (da)	1987-04-18	Heterocykliske forbindelser
DK219986A (da)	1986-12-01	Nitrogenholdige heterocycliske forbindelser
MC1729A1 (fr)	1986-12-15	Sels polycycliques
KR890700128A (ko)	1989-03-02	세팔로스포린 유도체
IT8548071A1 (it)	1986-11-13	Cefalosporina alogenidrato cristallino
IT1200125B (it)	1989-01-05	Composti di cefalosporina e procedimento per produrli
PH23442A (en)	1989-08-07	Cephalosporin derivatives and salts thereof
DK166385D0 (da)	1985-04-12	Cephalosporinderivater samt salte deraf
DK397686A (da)	1987-02-22	Heterocycliske forbindelser
DK109586A (da)	1986-10-05	Heterocycliske forbindelser
DK414886D0 (da)	1986-08-29	Substituerede heterocycliske forbindelser
PH21201A (en)	1987-08-19	Cephalosporin derivatives and salts thereof
IL88959A (en)	1992-02-16	Cephalosporin salts and injectable compositions
DK577286A (da)	1986-12-01	Cephalosporinderivater
RO92098A2 (fr)	1987-07-30	Composition additive
DK422085D0 (da)	1985-09-17	Heterocycliske forbindelser
LV5743A4 (lv)	1996-10-20	Heterocikliskie savienojumi
DK280485D0 (da)	1985-06-21	Forskydeligt tremmegitter
DK271286A (da)	1986-12-12	Antibakterielt virksomme forbindelser

Legal Events

Date	Code	Title	Description
1993-12-23	CP	Supplementary protection certificate (spc) filed	Free format text: PRODUCT NAME: CEFEPIME HYDROCHLORIDE; NAT. REGISTRATION NO/DATE: NL 18323 19930727; FIRST REGISTRATION: Spc suppl protection certif: 93C0068 Filing date: 19931223
1994-03-11	CD	Change of name or company name
1995-01-06	CR	Request for supplementary protection certificate laid open to the public (eec regulation of 18 june 1992)	Free format text: BO 44/94 PAGE 209:LIRE 2585705 AU LIEU DE 2586705
1995-09-22	CP	Supplementary protection certificate (spc) filed