FR2429772A1 - Procede pour l'obtention d'acides arylpyruviques - Google Patents
Procede pour l'obtention d'acides arylpyruviquesInfo
- Publication number
- FR2429772A1 FR2429772A1 FR7916170A FR7916170A FR2429772A1 FR 2429772 A1 FR2429772 A1 FR 2429772A1 FR 7916170 A FR7916170 A FR 7916170A FR 7916170 A FR7916170 A FR 7916170A FR 2429772 A1 FR2429772 A1 FR 2429772A1
- Authority
- FR
- France
- Prior art keywords
- obtaining
- acids
- arylpyruvic
- alcohol
- reaction
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000002253 acid Substances 0.000 title abstract 3
- 150000007513 acids Chemical class 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 abstract 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
- WMFOQBRAJBCJND-UHFFFAOYSA-M Lithium hydroxide Chemical compound [Li+].[OH-] WMFOQBRAJBCJND-UHFFFAOYSA-M 0.000 abstract 2
- 229910001854 alkali hydroxide Inorganic materials 0.000 abstract 2
- 150000008044 alkali metal hydroxides Chemical class 0.000 abstract 2
- -1 arylmethyl halides Chemical class 0.000 abstract 2
- 150000007514 bases Chemical class 0.000 abstract 2
- UGFAIRIUMAVXCW-UHFFFAOYSA-N Carbon monoxide Chemical compound [O+]#[C-] UGFAIRIUMAVXCW-UHFFFAOYSA-N 0.000 abstract 1
- COLNVLDHVKWLRT-QMMMGPOBSA-N L-phenylalanine Chemical compound OC(=O)[C@@H](N)CC1=CC=CC=C1 COLNVLDHVKWLRT-QMMMGPOBSA-N 0.000 abstract 1
- 150000001371 alpha-amino acids Chemical class 0.000 abstract 1
- 235000008206 alpha-amino acids Nutrition 0.000 abstract 1
- 229910002091 carbon monoxide Inorganic materials 0.000 abstract 1
- 229910017052 cobalt Inorganic materials 0.000 abstract 1
- 239000010941 cobalt Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- COLNVLDHVKWLRT-UHFFFAOYSA-N phenylalanine Natural products OC(=O)C(N)CC1=CC=CC=C1 COLNVLDHVKWLRT-UHFFFAOYSA-N 0.000 abstract 1
- 239000002994 raw material Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/10—Preparation of carboxylic acids or their salts, halides or anhydrides by reaction with carbon monoxide
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
Procédé pour l'obtention d'acides arylpyruviques, qui peuvent être éventuellement substitués, par réaction d'halogénures d'arylméthyle éventuellement substitués, avec l'oxyde de carbone et un mélange alcool/eau en présence d'un cobalt carbonyle et d'un composé basique. On conduit la réaction à une température de -10 à 70 degrés C en présence d'un alcool et d'un hydroxyde alcalin comme composé basique Comme hydroxyde alcalin, on utilise de préférence LiOH ou NaOH. Les acides arylpyruviques sont des matières premières importantes pour la préparation d'acides alpha -aminés, tels que par exemple la phénylalanine.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE2828041A DE2828041C2 (de) | 1978-06-26 | 1978-06-26 | Verfahren zur Herstellung von Arylbrenztraubensäuren |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2429772A1 true FR2429772A1 (fr) | 1980-01-25 |
FR2429772B1 FR2429772B1 (fr) | 1983-08-26 |
Family
ID=6042822
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7916170A Granted FR2429772A1 (fr) | 1978-06-26 | 1979-06-22 | Procede pour l'obtention d'acides arylpyruviques |
Country Status (13)
Country | Link |
---|---|
US (1) | US4447644A (fr) |
JP (1) | JPS554398A (fr) |
BE (1) | BE877229A (fr) |
BR (1) | BR7903978A (fr) |
CA (1) | CA1125307A (fr) |
CH (1) | CH644343A5 (fr) |
DD (1) | DD144536A5 (fr) |
DE (1) | DE2828041C2 (fr) |
FR (1) | FR2429772A1 (fr) |
GB (1) | GB2026478B (fr) |
IT (1) | IT1120442B (fr) |
MX (1) | MX149923A (fr) |
NL (1) | NL7904941A (fr) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2535704A1 (fr) * | 1982-11-05 | 1984-05-11 | Rhone Poulenc Spec Chim | Procede d'obtention de cobalttetracarbonylates alcalins ou alcalino-terreux et de leurs solutions et leur application a la carbonylation de composes a groupes halogenomethyle |
EP0108698A1 (fr) * | 1982-11-05 | 1984-05-16 | Rhone-Poulenc Chimie | Procédé d'obtention de cobalttétracarbonylates alcalinoterreax et de leurs solutions et leur application à la carbonylation de composés à groupes halogénométhyle |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1198351B (it) * | 1981-09-21 | 1988-12-21 | Montedison Spa | Processo per la carbonilazione di alogenuri benzilici secondari |
IT1139455B (it) * | 1981-09-21 | 1986-09-24 | Montedison Spa | Processo per la preparazione di acidi alfa-arilpropionici e loro sali alcalini |
IT1140323B (it) * | 1981-12-09 | 1986-09-24 | Montedison Spa | Processo per la preparazione di composti carbossilati aromatici o etero-aromatici |
US4492798A (en) * | 1982-03-01 | 1985-01-08 | Ethyl Corporation | Process for preparing arylalkylpyruvic acids |
US4738802A (en) * | 1982-03-01 | 1988-04-19 | Ethyl Corporation | Process for preparing alkyl α-keto-carboxylic acids from alkyl halides |
US4473706A (en) * | 1982-08-06 | 1984-09-25 | Ethyl Corporation | Preparation of cyclic-keto-acids |
EP0134216A4 (fr) * | 1983-01-13 | 1985-07-01 | Ethyl Corp | PROCEDE DE PREPARATION D'ACIDES -g(a)-CETO-CARBOXYLIQUES. |
US4481368A (en) * | 1983-07-28 | 1984-11-06 | Ethyl Corporation | Process for preparing α-keto-carboxylic acids from acyl halides |
US4481369A (en) * | 1983-07-28 | 1984-11-06 | Ethyl Corporation | Preparation of α-keto-carboxylic acids from acyl halides |
US4544505A (en) * | 1983-10-21 | 1985-10-01 | Ethyl Corporation | Preparation of halo-α-keto-carboxylic acids |
DE3438439A1 (de) * | 1983-10-26 | 1985-05-09 | Daido Tokushuko K.K., Nagoya, Aichi | Pulveroberflaechenschweissverfahren |
JPS61500428A (ja) * | 1983-11-14 | 1986-03-13 | エシル コ−ポレ−シヨン | ビス−α−ケトカルボン酸の製法 |
WO1985002181A1 (fr) * | 1983-11-15 | 1985-05-23 | Ethyl Corporation | Preparation de ceto-acides cycliques |
JPS61500663A (ja) * | 1983-12-13 | 1986-04-10 | コモンウエルス サイエンテイフイツク アンド インダストリアル リサ−チ オ−ガナイゼイシヨン | 感染性嚢病ウィルスワクチン |
DE3345411A1 (de) * | 1983-12-15 | 1985-06-27 | Dynamit Nobel Ag, 5210 Troisdorf | Verfahren zur reindarstellung von carbonsaeuren |
US4689431A (en) * | 1985-02-21 | 1987-08-25 | Japan As Represented By General Director Of Agency Of Industrial Science And Technology | Method for the preparation of phenyl pyruvic acid |
FR2590565B1 (fr) * | 1985-11-27 | 1988-01-08 | Rhone Poulenc Spec Chim | Procede de preparation d'alpha-hydroxyacides |
FR2629816B1 (fr) * | 1988-04-06 | 1990-09-07 | Rhone Poulenc Chimie | Procede de preparation de phenylpyruvate alcalin |
US4948920A (en) * | 1989-03-24 | 1990-08-14 | The Nutrasweet Company | Process for the preparation of phenylpyruvic acid from benzyl chloride |
JP7138106B2 (ja) | 2016-12-23 | 2022-09-15 | ノバルティス アーゲー | 初期サクビトリル中間体のための新規な方法 |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2208878A1 (fr) * | 1972-12-02 | 1974-06-28 | Dynamit Nobel Ag |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL272335A (fr) * | 1960-12-08 | |||
DE2600541C3 (de) * | 1975-01-09 | 1978-06-08 | Rhone-Poulenc Industries, S.A., Paris | Verfahren zur Herstellung von Phenylbrenztraubensäure oder Arylbrenztraubensäuren |
US4351952A (en) * | 1980-07-01 | 1982-09-28 | Montedison S.P.A. | Process for preparing phenyl pyruvic acids |
-
1978
- 1978-06-26 DE DE2828041A patent/DE2828041C2/de not_active Expired
-
1979
- 1979-03-27 MX MX177082A patent/MX149923A/es unknown
- 1979-06-22 DD DD79213844A patent/DD144536A5/de unknown
- 1979-06-22 FR FR7916170A patent/FR2429772A1/fr active Granted
- 1979-06-22 CA CA330,652A patent/CA1125307A/fr not_active Expired
- 1979-06-25 GB GB7922073A patent/GB2026478B/en not_active Expired
- 1979-06-25 NL NL7904941A patent/NL7904941A/xx not_active Application Discontinuation
- 1979-06-25 CH CH592679A patent/CH644343A5/de not_active IP Right Cessation
- 1979-06-25 BR BR7903978A patent/BR7903978A/pt unknown
- 1979-06-25 BE BE0/195931A patent/BE877229A/fr not_active IP Right Cessation
- 1979-06-25 IT IT49532/79A patent/IT1120442B/it active
- 1979-06-26 JP JP7977279A patent/JPS554398A/ja active Pending
-
1982
- 1982-05-24 US US06/381,133 patent/US4447644A/en not_active Expired - Fee Related
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2208878A1 (fr) * | 1972-12-02 | 1974-06-28 | Dynamit Nobel Ag |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2535704A1 (fr) * | 1982-11-05 | 1984-05-11 | Rhone Poulenc Spec Chim | Procede d'obtention de cobalttetracarbonylates alcalins ou alcalino-terreux et de leurs solutions et leur application a la carbonylation de composes a groupes halogenomethyle |
EP0108698A1 (fr) * | 1982-11-05 | 1984-05-16 | Rhone-Poulenc Chimie | Procédé d'obtention de cobalttétracarbonylates alcalinoterreax et de leurs solutions et leur application à la carbonylation de composés à groupes halogénométhyle |
Also Published As
Publication number | Publication date |
---|---|
DE2828041A1 (de) | 1980-01-03 |
CA1125307A (fr) | 1982-06-08 |
US4447644A (en) | 1984-05-08 |
CH644343A5 (de) | 1984-07-31 |
DE2828041C2 (de) | 1984-05-10 |
FR2429772B1 (fr) | 1983-08-26 |
IT7949532A0 (it) | 1979-06-25 |
DD144536A5 (de) | 1980-10-22 |
IT1120442B (it) | 1986-03-26 |
GB2026478B (en) | 1982-10-06 |
BR7903978A (pt) | 1980-03-11 |
JPS554398A (en) | 1980-01-12 |
NL7904941A (nl) | 1979-12-28 |
BE877229A (fr) | 1979-10-15 |
MX149923A (es) | 1984-02-09 |
GB2026478A (en) | 1980-02-06 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |