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FR19C1046I2 - (+)-2-[1-(3-ETHOXY-4-METHOXYPHENYL)-2-METHYLSULPHONYLETHYL]-4-ACETYLAMINOISOINDOLINE-1,3-DIONE: METHODS OF USE AND COMPOSITIONS THEREOF - Google Patents

(+)-2-[1-(3-ETHOXY-4-METHOXYPHENYL)-2-METHYLSULPHONYLETHYL]-4-ACETYLAMINOISOINDOLINE-1,3-DIONE: METHODS OF USE AND COMPOSITIONS THEREOF

Info

Publication number
FR19C1046I2
FR19C1046I2 FR19C1046C FR19C1046C FR19C1046I2 FR 19C1046 I2 FR19C1046 I2 FR 19C1046I2 FR 19C1046 C FR19C1046 C FR 19C1046C FR 19C1046 C FR19C1046 C FR 19C1046C FR 19C1046 I2 FR19C1046 I2 FR 19C1046I2
Authority
FR
France
Prior art keywords
acetylaminoisoindoline
dione
methoxyphenyl
ethoxy
methylsulphonylethyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
FR19C1046C
Other languages
French (fr)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Celgene Corp
Original Assignee
Celgene Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=28457137&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FR19C1046(I2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Celgene Corp filed Critical Celgene Corp
Publication of FR19C1046I1 publication Critical patent/FR19C1046I1/en
Application granted granted Critical
Publication of FR19C1046I2 publication Critical patent/FR19C1046I2/en
Active legal-status Critical Current

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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/4035—Isoindoles, e.g. phthalimide
    • A—HUMAN NECESSITIES
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    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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    • C—CHEMISTRY; METALLURGY
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    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/26—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C317/28—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to acyclic carbon atoms of the carbon skeleton
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    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
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    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
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    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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Abstract

Discussed is stereomerically pure (+)-2-[1-(3-Ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione, or a pharmaceutically acceptable polymorph, salt, solvate or hydrate thereof, as well as a pharmaceutical composition or single unit dosage form comprising such compound and such compound for use as a medicine.
FR19C1046C 2002-03-20 2019-07-12 (+)-2-[1-(3-ETHOXY-4-METHOXYPHENYL)-2-METHYLSULPHONYLETHYL]-4-ACETYLAMINOISOINDOLINE-1,3-DIONE: METHODS OF USE AND COMPOSITIONS THEREOF Active FR19C1046I2 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US36651502P 2002-03-20 2002-03-20
US43845003P 2003-01-07 2003-01-07
EP09003138.6A EP2074995B1 (en) 2002-03-20 2003-03-20 (+)-2-[1-(3-Ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione: methods of using and compositions thereof
PCT/US2003/008738 WO2003080049A1 (en) 2002-03-20 2003-03-20 (+)-2-[1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione: methods of using and compositions thereof
EP03721414A EP1485087B1 (en) 2002-03-20 2003-03-20 (+)-2- [1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione for use in treating psoriasis by oral administration

Publications (2)

Publication Number Publication Date
FR19C1046I1 FR19C1046I1 (en) 2019-08-09
FR19C1046I2 true FR19C1046I2 (en) 2022-07-08

Family

ID=28457137

Family Applications (1)

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FR19C1046C Active FR19C1046I2 (en) 2002-03-20 2019-07-12 (+)-2-[1-(3-ETHOXY-4-METHOXYPHENYL)-2-METHYLSULPHONYLETHYL]-4-ACETYLAMINOISOINDOLINE-1,3-DIONE: METHODS OF USE AND COMPOSITIONS THEREOF

Country Status (24)

Country Link
US (14) US6962940B2 (en)
EP (9) EP2420490B1 (en)
JP (4) JP2005525386A (en)
KR (6) KR101104991B1 (en)
CN (2) CN100427085C (en)
AT (1) ATE440599T1 (en)
AU (1) AU2003224729C1 (en)
BE (1) BE2019C008I2 (en)
CA (2) CA2756798A1 (en)
CY (6) CY1109380T1 (en)
DE (1) DE60328974D1 (en)
DK (6) DK2223687T3 (en)
ES (8) ES2635361T3 (en)
FR (1) FR19C1046I2 (en)
HK (3) HK1073426A1 (en)
HU (5) HUE034348T2 (en)
IL (3) IL164147A0 (en)
LU (1) LUC00125I2 (en)
MX (2) MXPA04009075A (en)
NL (1) NL300994I2 (en)
NZ (1) NZ535798A (en)
PT (6) PT2223688T (en)
SI (5) SI2223688T1 (en)
WO (1) WO2003080049A1 (en)

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