FI954616L - Heterosyklisiä johdannaisia verihiutaleiden kasaantumisen inhibiittoreina - Google Patents
Heterosyklisiä johdannaisia verihiutaleiden kasaantumisen inhibiittoreina Download PDFInfo
- Publication number
- FI954616L FI954616L FI954616A FI954616A FI954616L FI 954616 L FI954616 L FI 954616L FI 954616 A FI954616 A FI 954616A FI 954616 A FI954616 A FI 954616A FI 954616 L FI954616 L FI 954616L
- Authority
- FI
- Finland
- Prior art keywords
- platelet aggregation
- aggregation inhibitors
- heterocyclic derivatives
- heterocyclic
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Electroluminescent Light Sources (AREA)
- Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
- Electrochromic Elements, Electrophoresis, Or Variable Reflection Or Absorption Elements (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Peptides Or Proteins (AREA)
- Pyridine Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB939306453A GB9306453D0 (en) | 1993-03-29 | 1993-03-29 | Heterocyclic derivatives |
GB939325605A GB9325605D0 (en) | 1993-12-15 | 1993-12-15 | Heterocyclic derivatives |
PCT/GB1994/000647 WO1994022834A1 (en) | 1993-03-29 | 1994-03-28 | Heterocyclic derivatives as platelet aggregation inhibitors |
Publications (2)
Publication Number | Publication Date |
---|---|
FI954616L true FI954616L (fi) | 1995-09-28 |
FI954616A0 FI954616A0 (fi) | 1995-09-28 |
Family
ID=26302668
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI954616A FI954616A0 (fi) | 1993-03-29 | 1995-09-28 | Heterosyklisiä johdannaisia verihiutaleiden kasaantumisen inhibiittoreina |
Country Status (26)
Country | Link |
---|---|
US (1) | US5556977A (fi) |
EP (2) | EP0691959B1 (fi) |
JP (1) | JPH08508291A (fi) |
KR (1) | KR100231089B1 (fi) |
CN (1) | CN1120334A (fi) |
AT (2) | ATE202345T1 (fi) |
AU (1) | AU692438B2 (fi) |
BR (1) | BR9406613A (fi) |
CA (1) | CA2156070A1 (fi) |
CZ (1) | CZ250995A3 (fi) |
DE (2) | DE69427548T2 (fi) |
DK (2) | DK0825184T3 (fi) |
ES (2) | ES2159798T3 (fi) |
FI (1) | FI954616A0 (fi) |
GB (1) | GB9406143D0 (fi) |
GR (2) | GR3027751T3 (fi) |
HU (2) | HUT72088A (fi) |
IL (1) | IL109144A (fi) |
NO (1) | NO305244B1 (fi) |
NZ (1) | NZ262941A (fi) |
PL (1) | PL310889A1 (fi) |
PT (1) | PT825184E (fi) |
SK (1) | SK120895A3 (fi) |
TW (1) | TW276254B (fi) |
WO (1) | WO1994022834A1 (fi) |
ZW (1) | ZW4294A1 (fi) |
Families Citing this family (43)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5750754A (en) * | 1993-03-29 | 1998-05-12 | Zeneca Limited | Heterocyclic compounds |
IL115420A0 (en) | 1994-09-26 | 1995-12-31 | Zeneca Ltd | Aminoheterocyclic derivatives |
US5700801A (en) * | 1994-12-23 | 1997-12-23 | Karl Thomae, Gmbh | Piperazine derivatives, pharmaceutical compositions containing these compounds, their use and processes for preparing them |
CZ189197A3 (cs) * | 1994-12-23 | 1998-01-14 | Dr. Karl Thomae Gmbh | Piperazinové deriváty, způsob výroby a farmaceutický prostředek s jejich obsahem |
MX9700379A (es) * | 1995-06-01 | 1997-04-30 | Zeneca Ltd | Acido(-)-(3r)-3-metil-4-(4-(4-(4-piridil)piperazin-1-il)-fenoxi)butirico como inhibidor de la adhesion celular. |
FR2734818B1 (fr) * | 1995-06-01 | 1998-07-10 | Zeneca Ltd | Acide (-)-(3r)-3-methyl-4-{4-[4-(4-pyridyl)piperazine-1-yl- phenoxy}-butyrique, procede pour sa preparation et composition pharmaceutique le contenant |
DE19524765A1 (de) * | 1995-07-07 | 1997-01-09 | Boehringer Mannheim Gmbh | Neue Oxazolidinonderivate, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel |
BR9611487A (pt) * | 1995-11-17 | 1999-01-19 | Warner Lambert Co | Inibidores de sulfonamida de metaloproteinases de matriz |
GB9525620D0 (en) * | 1995-12-15 | 1996-02-14 | Glaxo Group Ltd | Chemical compounds |
WO1997028128A1 (en) * | 1996-02-02 | 1997-08-07 | Zeneca Limited | Heterocyclic compounds useful as pharmaceutical agents |
GB9602166D0 (en) * | 1996-02-02 | 1996-04-03 | Zeneca Ltd | Aminoheterocyclic derivatives |
US5780480A (en) * | 1996-02-28 | 1998-07-14 | Merck & Co., Inc. | Fibrinogen receptor antagonists |
CA2246756A1 (en) * | 1996-02-28 | 1997-09-04 | Merck & Co., Inc. | Fibrinogen receptor antagonists |
AU2044297A (en) * | 1996-03-29 | 1997-10-22 | Meiji Seika Kaisha Ltd. | Novel heterocyclic compounds having platelet aggregation inhibitory effects |
US5990107A (en) * | 1996-06-28 | 1999-11-23 | Merck & Co., Inc. | Fibrinogen receptor antagonist prodrugs |
US5854245A (en) * | 1996-06-28 | 1998-12-29 | Merck & Co., Inc. | Fibrinogen receptor antagonists |
AU709631B2 (en) * | 1996-06-28 | 1999-09-02 | Merck & Co., Inc. | Fibrinogen receptor antagonist prodrugs |
US5932582A (en) * | 1996-06-28 | 1999-08-03 | Merck & Co., Inc. | Fibrinogen receptor antagonist prodrugs |
AU721130B2 (en) * | 1996-06-28 | 2000-06-22 | Merck & Co., Inc. | Fibrinogen receptor antagonists |
GB9821483D0 (en) | 1998-10-03 | 1998-11-25 | Glaxo Group Ltd | Chemical compounds |
UA56197C2 (uk) | 1996-11-08 | 2003-05-15 | Зенека Лімітед | Гетероциклічні похідні |
US5945545A (en) * | 1996-12-13 | 1999-08-31 | Merck & Co., Inc. | Fibrinogen receptor antagonists |
EP0966462B1 (en) | 1997-02-13 | 2003-06-11 | AstraZeneca AB | Heterocyclic compounds useful as oxido-squalene cyclase inhibitors |
EP0966460A1 (en) | 1997-02-13 | 1999-12-29 | Zeneca Limited | Heterocyclic compounds useful as oxido-squalene cyclase inhibitors |
GB9715895D0 (en) | 1997-07-29 | 1997-10-01 | Zeneca Ltd | Heterocyclic compounds |
US6166069A (en) | 1998-05-12 | 2000-12-26 | American Home Products Corporation | Phenyl oxo-acetic acids useful in the treatment of insulin resistance and hyperglycemia |
JP2002516305A (ja) | 1998-05-12 | 2002-06-04 | アメリカン・ホーム・プロダクツ・コーポレイション | インスリン抵抗性および高血糖症の治療に有用な2,3,5−置換ビフェニル |
US6232322B1 (en) | 1998-05-12 | 2001-05-15 | American Home Products Corporation | Biphenyl oxo-acetic acids useful in the treatment of insulin resistance and hyperglycemia |
US6110963A (en) * | 1998-05-12 | 2000-08-29 | American Home Products Corporation | Aryl-oxo-acetic acids useful in the treatment of insulin resistance and hyperglycemia |
US6699896B1 (en) | 1998-05-12 | 2004-03-02 | Wyeth | Oxazole-aryl-carboxylic acids useful in the treatment of insulin resistance and hyperglycemia |
US6451827B2 (en) | 1998-05-12 | 2002-09-17 | Wyeth | 2,3,5-substituted biphenyls useful in the treatment of insulin resistance and hyperglycemia |
US6221902B1 (en) | 1998-05-12 | 2001-04-24 | American Home Products Corporation | Biphenyl sulfonyl aryl carboxylic acids useful in the treatment of insulin resistance and hyperglycemia |
CA2338745A1 (en) | 1998-07-31 | 2000-02-10 | Hamideh Zarrinmayeh | Heterocyclyl sulphonamide derivatives |
GB9902989D0 (en) | 1999-02-11 | 1999-03-31 | Zeneca Ltd | Heterocyclic derivatives |
DE60021368T2 (de) * | 1999-04-19 | 2006-07-27 | Lexicon Pharmaceuticals (New Jersey), Inc. | Ppar-(gamma) agonisten zur behandlung von type ii diabetes |
US6310081B1 (en) | 1999-05-10 | 2001-10-30 | American Home Products Corporation | Biphenyl sulfonyl aryl carboxylic acids useful in the treatment of insulin resistance and hyperglycemia |
AU2002217999A1 (en) | 2000-11-01 | 2002-05-15 | Cor Therapeutics, Inc. | Process for the production of 4-quinazolinylpiperazin-1-carboxylic acid phenylamides |
DE202011000090U1 (de) | 2011-01-14 | 2011-04-21 | E-LEAD ELECTRONIC CO., LTD., Shengang Shiang | Fahrzeug-Audiosystem mit auswechselbarem Plug-In-Computer |
SG11202002032SA (en) | 2017-09-22 | 2020-04-29 | Jubilant Epipad LLC | Heterocyclic compounds as pad inhibitors |
MX2020003341A (es) | 2017-10-18 | 2020-09-17 | Jubilant Epipad LLC | Compuestos de imidazo-piridina como inhibidores de pad. |
EP3707135A1 (en) | 2017-11-06 | 2020-09-16 | Jubilant Prodel LLC | Pyrimidine derivatives as inhibitors of pd1/pd-l1 activation |
HRP20240736T1 (hr) | 2017-11-24 | 2024-11-08 | Jubilant Episcribe Llc | Heterociklički spojevi kao inhibitori prmt5 |
BR112020018610A2 (pt) | 2018-03-13 | 2020-12-29 | Jubilant Prodel LLC | Compostos de fórmula i, fórmula ii, fórmula iii, fórmula iv, fórmula v, fórmula vi, ou seus polimorfos, estereoisômeros, tautômeros, profármacos, solvatos e sais farmaceuticamente aceitáveis dos mesmos e uso dos mesmos; processo de preparação; composição farmacêutica; e método para o tratamento e/ou prevenção de várias doenças, que incluem câncer e doenças infecciosas |
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UA39849C2 (uk) * | 1991-03-26 | 2001-07-16 | Ф.Хоффманн-Ля Рош Аг | ПОХІДНІ N-АЦИЛ-<font face="Symbol">a</font>-АМІНОКИСЛОТИ АБО ЇХ ФІЗІОЛОГІЧНО ПРИЙНЯТНІ СОЛІ, ПРОСТІ АБО СКЛАДНІ ЕФІРИ, АМІДИ АБО ЇХ ГІДРАТИ ЯК ФАРМАЦЕВТИЧНО АКТИВНІ РЕЧОВИНИ |
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DE4124942A1 (de) * | 1991-07-27 | 1993-01-28 | Thomae Gmbh Dr K | 5-gliedrige heterocyclen, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
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US5239113A (en) * | 1991-10-15 | 1993-08-24 | Monsanto Company | Substituted β-amino acid derivatives useful as platelet aggregation inhibitors and intermediates thereof |
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WO1993014077A1 (en) * | 1992-01-21 | 1993-07-22 | Glaxo Group Limited | Piperidineacetic acid derivatives as inhibitors of fibrinogen-dependent blood platelet aggregation |
US5264457A (en) * | 1992-02-14 | 1993-11-23 | G. D. Searle & Co. | Phenyl amidines sulfonamides useful as platelet aggregation inhibitors |
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DE4212304A1 (de) * | 1992-04-13 | 1993-10-14 | Cassella Ag | Asparaginsäurederivate, ihre Herstellung und Verwendung |
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DE4213634A1 (de) * | 1992-04-24 | 1993-10-28 | Cassella Ag | 2,4-Dioxo-imidazolidin-Derivate |
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TW301607B (fi) * | 1993-03-09 | 1997-04-01 | Takeda Pharm Industry Co Ltd |
-
1994
- 1994-03-28 DK DK97117909T patent/DK0825184T3/da active
- 1994-03-28 US US08/218,171 patent/US5556977A/en not_active Expired - Fee Related
- 1994-03-28 CZ CZ952509A patent/CZ250995A3/cs unknown
- 1994-03-28 DE DE69427548T patent/DE69427548T2/de not_active Expired - Fee Related
- 1994-03-28 JP JP6521810A patent/JPH08508291A/ja active Pending
- 1994-03-28 ES ES97117909T patent/ES2159798T3/es not_active Expired - Lifetime
- 1994-03-28 AT AT97117909T patent/ATE202345T1/de not_active IP Right Cessation
- 1994-03-28 CN CN94191664A patent/CN1120334A/zh active Pending
- 1994-03-28 AU AU62889/94A patent/AU692438B2/en not_active Ceased
- 1994-03-28 NZ NZ262941A patent/NZ262941A/en unknown
- 1994-03-28 EP EP94910494A patent/EP0691959B1/en not_active Expired - Lifetime
- 1994-03-28 PL PL94310889A patent/PL310889A1/xx unknown
- 1994-03-28 WO PCT/GB1994/000647 patent/WO1994022834A1/en not_active Application Discontinuation
- 1994-03-28 AT AT94910494T patent/ATE168678T1/de not_active IP Right Cessation
- 1994-03-28 ZW ZW4294A patent/ZW4294A1/xx unknown
- 1994-03-28 SK SK1208-95A patent/SK120895A3/sk unknown
- 1994-03-28 IL IL10914494A patent/IL109144A/xx not_active IP Right Cessation
- 1994-03-28 DK DK94910494T patent/DK0691959T3/da active
- 1994-03-28 GB GB9406143A patent/GB9406143D0/en active Pending
- 1994-03-28 HU HU9502290A patent/HUT72088A/hu unknown
- 1994-03-28 BR BR9406613A patent/BR9406613A/pt not_active Application Discontinuation
- 1994-03-28 TW TW083102802A patent/TW276254B/zh active
- 1994-03-28 KR KR1019950704314A patent/KR100231089B1/ko not_active Expired - Fee Related
- 1994-03-28 DE DE69411900T patent/DE69411900T2/de not_active Expired - Fee Related
- 1994-03-28 EP EP97117909A patent/EP0825184B1/en not_active Expired - Lifetime
- 1994-03-28 CA CA002156070A patent/CA2156070A1/en not_active Abandoned
- 1994-03-28 ES ES94910494T patent/ES2119184T3/es not_active Expired - Lifetime
- 1994-03-28 PT PT97117909T patent/PT825184E/pt unknown
-
1995
- 1995-06-13 HU HU95P/P00193P patent/HU211336A9/hu unknown
- 1995-09-28 NO NO953837A patent/NO305244B1/no not_active IP Right Cessation
- 1995-09-28 FI FI954616A patent/FI954616A0/fi unknown
-
1998
- 1998-08-27 GR GR980401930T patent/GR3027751T3/el unknown
-
2001
- 2001-09-18 GR GR20010401498T patent/GR3036640T3/el not_active IP Right Cessation
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