FI953851L - Silybidut asetyylikoliiniesteraase-inhibiittorit - Google Patents

Silybidut asetyylikoliiniesteraase-inhibiittorit Download PDF

Info

Publication number: FI953851L
Authority: FI; Finland
Prior art keywords: silybid; acetylcholinesterase inhibitors; acetylcholinesterase; inhibitors; silybid acetylcholinesterase
Prior art date: 1993-02-16

Application number

FI953851A

Other languages

English (en)

Swedish (sv)

Other versions

FI953851A0 (fi

FI111461B (fi

Inventor

Jean-Noel Collard

Jean-Marie Hornsperger

Original Assignee

Merrell Dow Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-02-16

Filing date

1995-08-15

Publication date

1995-08-15

1995-08-15 Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma

1995-08-15 Publication of FI953851A0 publication Critical patent/FI953851A0/fi

1995-08-15 Publication of FI953851L publication Critical patent/FI953851L/fi

2003-07-31 Application granted granted Critical

2003-07-31 Publication of FI111461B publication Critical patent/FI111461B/fi

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/0803—Compounds with Si-C or Si-Si linkages
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Neurosurgery (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Hospice & Palliative Care (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Psychiatry (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Steroid Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Enzymes And Modification Thereof (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Polysaccharides And Polysaccharide Derivatives (AREA)

FI953851A 1993-02-16 1995-08-15 Menetelmä terapeuttisesti käyttökelpoisten silyloitujen asetyylikoliiniesteraasi-inhibiittorien valmistamiseksi FI111461B (fi)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
EP93400385		1993-02-16
EP93400385A EP0611769A1 (en)	1993-02-16	1993-02-16	Silylated acetylcholinesterase inhibitors
US9400720		1994-01-25
PCT/US1994/000720 WO1994019356A1 (en)	1993-02-16	1994-01-25	Silylated acetylcholinesterase inhibitors

Publications (3)

Publication Number	Publication Date
FI953851A0 FI953851A0 (fi)	1995-08-15
FI953851L true FI953851L (fi)	1995-08-15
FI111461B FI111461B (fi)	2003-07-31

Family

ID=8214682

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI953851A FI111461B (fi)	1993-02-16	1995-08-15	Menetelmä terapeuttisesti käyttökelpoisten silyloitujen asetyylikoliiniesteraasi-inhibiittorien valmistamiseksi

Country Status (19)

Country	Link
EP (2)	EP0611769A1 (fi)
JP (1)	JP3516955B2 (fi)
KR (1)	KR100336547B1 (fi)
CN (1)	CN1043575C (fi)
AT (1)	ATE152725T1 (fi)
AU (1)	AU672885B2 (fi)
CA (1)	CA2154870C (fi)
DE (1)	DE69403068T2 (fi)
DK (1)	DK0684951T3 (fi)
ES (1)	ES2104358T3 (fi)
FI (1)	FI111461B (fi)
GR (1)	GR3024151T3 (fi)
HU (1)	HUT72736A (fi)
IL (1)	IL108623A0 (fi)
MX (1)	MX9401175A (fi)
NO (1)	NO305517B1 (fi)
NZ (1)	NZ262247A (fi)
WO (1)	WO1994019356A1 (fi)
ZA (1)	ZA94925B (fi)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0627400A1 (en) *	1993-06-04	1994-12-07	Merrell Dow Pharmaceuticals Inc.	Aromatic acetylcholinesterase inhibitors
CN100431539C (zh) *	2004-01-12	2008-11-12	和泓生物技术（上海）有限公司	乙酰胆碱酯酶抑制剂在制备治疗帕金森病药物中的应用
JP5379692B2 (ja)	2006-11-09	2013-12-25	プロビオドルグエージー	潰瘍、癌及び他の疾患の治療のためのグルタミニルシクラーゼの阻害薬としての３−ヒドロキシ−１，５−ジヒドロ−ピロール−２−オン誘導体
EP2091948B1 (en)	2006-11-30	2012-04-18	Probiodrug AG	Novel inhibitors of glutaminyl cyclase
EP2481408A3 (en)	2007-03-01	2013-01-09	Probiodrug AG	New use of glutaminyl cyclase inhibitors
EP2142514B1 (en)	2007-04-18	2014-12-24	Probiodrug AG	Thiourea derivatives as glutaminyl cyclase inhibitors
AU2010294214B2 (en)	2009-09-11	2015-05-07	Vivoryon Therapeutics N.V.	Heterocylcic derivatives as inhibitors of glutaminyl cyclase
AU2011215870B2 (en)	2010-02-09	2016-01-28	The Johns Hopkins University	Methods and compositions for improving cognitive function
ES2586231T3 (es)	2010-03-03	2016-10-13	Probiodrug Ag	Inhibidores de glutaminil ciclasa
MX2012010470A (es)	2010-03-10	2012-10-09	Probiodrug Ag	Inhibidores heterociclicos d ciclasa de glutaminilo (qc, ec .3 2. 5).
EP2560953B1 (en)	2010-04-21	2016-01-06	Probiodrug AG	Inhibitors of glutaminyl cyclase
EP2686313B1 (en)	2011-03-16	2016-02-03	Probiodrug AG	Benzimidazole derivatives as inhibitors of glutaminyl cyclase
WO2014078568A1 (en)	2012-11-14	2014-05-22	The Johns Hopkins University	Methods and compositions for treating schizophrenia
EP2968237A4 (en)	2013-03-15	2016-08-31	Univ Johns Hopkins	METHOD AND COMPOSITIONS FOR IMPROVING COGNITIVE FUNCTION
US11160785B2 (en)	2013-03-15	2021-11-02	Agenebio Inc.	Methods and compositions for improving cognitive function
MX2017014774A (es)	2015-05-22	2018-02-15	Agenebio Inc	Composiciones farmaceuticas de levetiracetam de liberacion extendida.
PL3461819T3 (pl)	2017-09-29	2020-11-30	Probiodrug Ag	Inhibitory cyklazy glutaminylowej
CN112047973B (zh) *	2019-06-06	2022-11-18	上海科技大学	一种大麻素类化合物，其制备方法、组合物和用途

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0403713A1 (en) *	1989-06-22	1990-12-27	Merrell Dow Pharmaceuticals Inc.	Novel acetylcholinesterase inhibitors

1993
- 1993-02-16 EP EP93400385A patent/EP0611769A1/en not_active Withdrawn
1994
- 1994-01-25 NZ NZ262247A patent/NZ262247A/en unknown
- 1994-01-25 EP EP94908615A patent/EP0684951B1/en not_active Expired - Lifetime
- 1994-01-25 DK DK94908615.1T patent/DK0684951T3/da active
- 1994-01-25 CA CA002154870A patent/CA2154870C/en not_active Expired - Fee Related
- 1994-01-25 CN CN94191196A patent/CN1043575C/zh not_active Expired - Fee Related
- 1994-01-25 AT AT94908615T patent/ATE152725T1/de active
- 1994-01-25 KR KR1019950703485A patent/KR100336547B1/ko not_active Expired - Fee Related
- 1994-01-25 WO PCT/US1994/000720 patent/WO1994019356A1/en active IP Right Grant
- 1994-01-25 DE DE69403068T patent/DE69403068T2/de not_active Expired - Lifetime
- 1994-01-25 JP JP51897494A patent/JP3516955B2/ja not_active Expired - Fee Related
- 1994-01-25 AU AU61641/94A patent/AU672885B2/en not_active Ceased
- 1994-01-25 ES ES94908615T patent/ES2104358T3/es not_active Expired - Lifetime
- 1994-01-25 HU HU9502406A patent/HUT72736A/hu unknown
- 1994-02-10 ZA ZA94925A patent/ZA94925B/xx unknown
- 1994-02-11 IL IL10862394A patent/IL108623A0/xx unknown
- 1994-02-15 MX MX9401175A patent/MX9401175A/es not_active Application Discontinuation
1995
- 1995-08-15 NO NO953201A patent/NO305517B1/no unknown
- 1995-08-15 FI FI953851A patent/FI111461B/fi not_active IP Right Cessation
1997
- 1997-07-16 GR GR970401801T patent/GR3024151T3/el unknown

Also Published As

Publication number	Publication date
CN1043575C (zh)	1999-06-09
FI953851A0 (fi)	1995-08-15
GR3024151T3 (en)	1997-10-31
CA2154870A1 (en)	1994-09-01
KR100336547B1 (ko)	2002-11-02
DE69403068T2 (de)	1997-12-11
NO305517B1 (no)	1999-06-14
DK0684951T3 (da)	1997-05-26
CA2154870C (en)	1998-10-27
AU672885B2 (en)	1996-10-17
IL108623A0 (en)	1994-05-30
NZ262247A (en)	1996-01-26
AU6164194A (en)	1994-09-14
HUT72736A (en)	1996-05-28
NO953201L (no)	1995-08-15
EP0684951A1 (en)	1995-12-06
ZA94925B (en)	1994-08-25
JPH08507059A (ja)	1996-07-30
MX9401175A (es)	1994-08-31
WO1994019356A1 (en)	1994-09-01
CN1117733A (zh)	1996-02-28
KR960701068A (ko)	1996-02-24
DE69403068D1 (en)	1997-06-12
ES2104358T3 (es)	1997-10-01
EP0684951B1 (en)	1997-05-07
EP0611769A1 (en)	1994-08-24
FI111461B (fi)	2003-07-31
JP3516955B2 (ja)	2004-04-05
ATE152725T1 (de)	1997-05-15
NO953201D0 (no)	1995-08-15

Publication	Publication Date	Title
NO942064D0 (no)	1994-06-03	yminhibitorer
FI963597L (fi)	1996-11-14	Isoprenyylitransferaasi-inhibiittoreita
NO972930D0 (no)	1997-06-23	Fibronectin-adhesjonsinhibitorer
BR9405832A (pt)	1995-12-26	Imidazoazinas
FI972160A0 (fi)	1997-05-21	Matriisimetalloproteaasi-inhibiittorit
FI953851L (fi)	1995-08-15	Silybidut asetyylikoliiniesteraase-inhibiittorit
NO305294B1 (no)	1999-05-03	R°rhenger
ATA146094A (de)	1996-04-15	Windsichter
DK0409676T3 (da)	1995-03-27	Acetylcholinesterase-inhibitorer
ATA212793A (de)	1996-01-15	Sportschuh
ATA194593A (de)	1996-01-15	Sportschuh
ATA179094A (de)	1997-07-15	Kettenschloss
DE69431454D1 (de)	2002-11-07	Amylase Inhibitoren
SE9302549D0 (sv)	1993-08-03	Time bloejan
SE9301252D0 (sv)	1993-04-16	Loestagbar traedurk foer baatar
SE9300970D0 (sv)	1993-03-24	Braensleinmatare foer fastbraenslepannor
FI934368A0 (fi)	1993-10-05	Dubbelregel foer foensterbaogar
CY2007006I2 (el)	2009-11-04	Αναστολεις συνθεσεις απολιποπρωτεϊνης-β
FI738U1 (fi)	1993-05-28	Form foer islykta
BR9301563A (pt)	1994-11-08	Generoso - bem bolado
FI932372A (fi)	1994-11-26	Toistin
FI787U1 (fi)	1993-07-06	Resultatblankett foer oevnings- och provskjutning
KR950002324U (ko)	1995-01-04	플리
ATE144907T1 (de)	1996-11-15	Rollbrett
BR9303364A (pt)	1994-04-19	Infratometro

Legal Events

Date	Code	Title	Description
2006-03-24	PC	Transfer of assignment of patent	Owner name: AVENTIS INC. Free format text: AVENTIS INC.
2010-06-09	PC	Transfer of assignment of patent	Owner name: AVENTISUB II INC. Free format text: AVENTISUB II INC.
2013-08-16	MM	Patent lapsed

Date

Code

Title

Description

2006-03-24

Transfer of assignment of patent

Owner name: AVENTIS INC.

Free format text: AVENTIS INC.

2010-06-09