FI943234L - Ihmisen Kunitz-tyyppisen proteaasiestäjän muunnos - Google Patents

Ihmisen Kunitz-tyyppisen proteaasiestäjän muunnos Download PDF

Info

Publication number: FI943234L
Authority: FI; Finland
Prior art keywords: protease inhibitor; type protease; human kunitz; inhibitor variant; variant
Prior art date: 1992-01-07

Application number

FI943234A

Other languages

English (en)

Swedish (sv)

Other versions

FI943234A0 (fi

Inventor

Fanny Norris

Kjeld Norris

Soeren Erik Bjoern

Lars Christian Petersen

Ole Hvilsted Olsen

Original Assignee

Novo Nordisk As

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-01-07

Filing date

1994-07-06

Publication date

1994-07-06

1994-07-06 Application filed by Novo Nordisk As filed Critical Novo Nordisk As

1994-07-06 Publication of FI943234A0 publication Critical patent/FI943234A0/fi

1994-07-06 Publication of FI943234L publication Critical patent/FI943234L/fi

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/81—Protease inhibitors
- C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
- C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
- C07K14/8114—Kunitz type inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Gastroenterology & Hepatology (AREA)
Rheumatology (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pain & Pain Management (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Enzymes And Modification Thereof (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

FI943234A 1992-01-07 1994-07-06 Ihmisen Kunitz-tyyppisen proteaasiestäjän muunnos FI943234L (fi)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
DK9200002		1992-01-07
DK9200340		1992-11-16
PCT/DK1993/000005 WO1993014122A1 (en)	1992-01-07	1993-01-07	A human kunitz-type protease inhibitor variant

Publications (2)

Publication Number	Publication Date
FI943234A0 FI943234A0 (fi)	1994-07-06
FI943234L true FI943234L (fi)	1994-07-06

Family

ID=26068350

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI943234A FI943234L (fi)	1992-01-07	1994-07-06	Ihmisen Kunitz-tyyppisen proteaasiestäjän muunnos

Country Status (13)

Country	Link
EP (1)	EP0621872A1 (fi)
JP (1)	JPH07504891A (fi)
AU (1)	AU675926B2 (fi)
CA (1)	CA2127246A1 (fi)
CZ (1)	CZ164494A3 (fi)
FI (1)	FI943234L (fi)
HU (1)	HUT70293A (fi)
IL (1)	IL104324A0 (fi)
NO (1)	NO942549L (fi)
NZ (1)	NZ246570A (fi)
RU (1)	RU94036773A (fi)
WO (1)	WO1993014122A1 (fi)
ZA (1)	ZA9396B (fi)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5455338A (en) *	1993-11-05	1995-10-03	Zymogenetics, Inc.	DNA encoding novel human kunitz-type inhibitors and methods relating thereto
JP3805785B2 (ja) *	1994-01-11	2006-08-09	ダイアックスコープ．	カリクレイン阻害クニッツドメイン蛋白質およびその相同体
US6010880A (en)	1994-01-11	2000-01-04	Dyax Corp.	Inhibitors of human plasmin derived from the kunitz domains
US6057287A (en) *	1994-01-11	2000-05-02	Dyax Corp.	Kallikrein-binding "Kunitz domain" proteins and analogues thereof
US5795954A (en) *	1994-03-04	1998-08-18	Genentech, Inc.	Factor VIIa inhibitors from Kunitz domain proteins
JP3779728B2 (ja) *	1994-08-05	2006-05-31	カイロンコーポレイション	組織因子活性インヒビターの産生
US5589359A (en) *	1994-08-05	1996-12-31	Chiron Corporation	Chimeric proteins
US5780265A (en) *	1995-06-05	1998-07-14	Genentech, Inc.	Kunitz type plasma kallikrein inhibitors
US5786328A (en) *	1995-06-05	1998-07-28	Genentech, Inc.	Use of kunitz type plasma kallikrein inhibitors
US6242414B1 (en)	1995-06-07	2001-06-05	Chiron Corporation	Regulation of cytokine synthesis and release
JPH11507060A (ja) *	1995-06-07	1999-06-22	カイロンコーポレイション	サイトカイン合成および放出の調節
US6521410B1 (en) *	1998-08-25	2003-02-18	Knut Kleesiek	Mutant of tissue factor pathway inhibitor, DNA sequence and use for detecting thrombotic disorders
CN1325889A (zh) *	2000-05-26	2001-12-12	上海博德基因开发有限公司	一种新的多肽——人Kazal型抑制因子11和编码这种多肽的多核苷酸
ES2372978T3 (es)	2002-06-07	2012-01-30	Dyax Corp.	Polipéptido con dominio de kunitz modificado.
US7153829B2 (en)	2002-06-07	2006-12-26	Dyax Corp.	Kallikrein-inhibitor therapies
ES2395014T3 (es) *	2002-08-28	2013-02-07	Dyax Corp.	Métodos para conservar órganos y tejidos
US6989369B2 (en)	2003-02-07	2006-01-24	Dyax Corp.	Kunitz domain peptides
DK1663281T3 (en)	2003-08-29	2014-03-17	Dyax Corp	POLY-PEGYLED PROTEASE INHIBITORS
US7235530B2 (en)	2004-09-27	2007-06-26	Dyax Corporation	Kallikrein inhibitors and anti-thrombolytic agents and uses thereof
US7276480B1 (en)	2005-12-30	2007-10-02	Dyax Corp.	Prevention and reduction of blood loss
NZ593815A (en)	2008-12-19	2013-05-31		Tissue factor pathway inhibitor (tfpi) inhibitors and methods of use
WO2010080833A1 (en)	2009-01-06	2010-07-15	Dyax Corp.	Treatment of mucositis with kallikrein inhibitors
AU2011204349C1 (en)	2010-01-06	2017-02-16	Takeda Pharmaceutical Company Limited	Plasma kallikrein binding proteins
BR112012023559A2 (pt)	2010-03-19	2017-10-17	Baxter Healthcare Sa	inibidores tfpi e métodos de uso
KR102011156B1 (ko)	2011-01-06	2019-08-16	다이액스 코포레이션	혈장 칼리크레인 결합 단백질
BR112014022435B1 (pt)	2012-03-21	2023-02-14	Takeda Pharmaceutical Company Limited	Inibidores de tfpi e métodos de uso
CO2018007151A2 (es)	2015-12-11	2018-09-20	Dyax Corp	Inhibidores de calicreína plasmática y usos de los mismos para tratar ataque de angioedema hereditario

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5106833A (en) *	1987-07-23	1992-04-21	Washington University	Coagulation inhibitors
DK408089D0 (da) *	1989-08-18	1989-08-18	Novo Nordisk As	Proteiner

1993
- 1993-01-06 IL IL104324A patent/IL104324A0/xx unknown
- 1993-01-07 NZ NZ246570A patent/NZ246570A/en unknown
- 1993-01-07 EP EP93902106A patent/EP0621872A1/en not_active Withdrawn
- 1993-01-07 HU HU9401990A patent/HUT70293A/hu unknown
- 1993-01-07 AU AU33460/93A patent/AU675926B2/en not_active Ceased
- 1993-01-07 ZA ZA9396A patent/ZA9396B/xx unknown
- 1993-01-07 JP JP5511993A patent/JPH07504891A/ja active Pending
- 1993-01-07 CA CA002127246A patent/CA2127246A1/en not_active Abandoned
- 1993-01-07 RU RU94036773/13A patent/RU94036773A/ru unknown
- 1993-01-07 CZ CZ941644A patent/CZ164494A3/cs unknown
- 1993-01-07 WO PCT/DK1993/000005 patent/WO1993014122A1/en not_active Application Discontinuation
1994
- 1994-07-06 NO NO942549A patent/NO942549L/no unknown
- 1994-07-06 FI FI943234A patent/FI943234L/fi unknown

Also Published As

Publication number	Publication date
NO942549L (no)	1994-09-07
RU94036773A (ru)	1996-09-27
JPH07504891A (ja)	1995-06-01
HU9401990D0 (en)	1994-09-28
FI943234A0 (fi)	1994-07-06
WO1993014122A1 (en)	1993-07-22
NZ246570A (en)	1996-09-25
CA2127246A1 (en)	1993-07-22
HUT70293A (en)	1995-09-28
CZ164494A3 (en)	1994-12-15
NO942549D0 (no)	1994-07-06
AU675926B2 (en)	1997-02-27
AU3346093A (en)	1993-08-03
EP0621872A1 (en)	1994-11-02
ZA9396B (en)	1993-08-10
IL104324A0 (en)	1993-05-13

Publication	Publication Date	Title
FI943233L (fi)	1994-07-06	Ihmisen Kunitz-tyyppisen proteaasiestäjän muunnos
FI961886L (fi)	1996-07-03	Ihmisen Kunitz-tyyppiset proteaasi-inhibiittorit
FI943232L (fi)	1994-07-06	Ihmisen Kunitz-tyyppisen proteaasiestäjän muunnos
FI943234L (fi)	1994-07-06	Ihmisen Kunitz-tyyppisen proteaasiestäjän muunnos
NO932620D0 (no)	1993-07-20	Amindiol-proteaseinhibitorer
FI943231L (fi)	1994-07-06	Ihmisen Kunitz-tyyppisen proteaasiestäjän muunnoksia
FI944033L (fi)	1994-09-02	Uusia proteaaseja
FI954647L (fi)	1995-09-29	Proteaasimuunnokset
DK0889036T3 (da)	2005-02-28	HIV-proteaseinhibitorer
FI944804A0 (fi)	1994-10-12	Pyrimidinyyliasetamideja elastaasin estäjinä
DE69328369D1 (de)	2000-05-18	Abgabeventil
FI925787L (fi)	1993-06-20	Proteolytiska enzymers sackarinderivatinhibitorer
NO20006716D0 (no)	2000-12-29	Proteaseinhibitorer
FI972029L (fi)	1997-05-13	Multikatalyyttisen proteaasin inhibiittoreita
FI943235L (fi)	1994-07-06	Uusi ihmisen Kunitz-tyyppinen proteaasiestäjä ja sen muunnnoksia
FI962488L (fi)	1996-06-14	HIV:n proteaasin inhibiittoreita
ITMI931620A0 (it)	1993-07-21	Pressostato
DE69302549D1 (de)	1996-06-13	Verdichter
MX9100121A (es)	1992-02-28	Inhibidores de proteasas asparticas
DE69315245D1 (de)	1998-01-02	Druckschalter
DE59302073D1 (de)	1996-05-02	Verdichteraggregat
FI960333L (fi)	1996-01-24	Tryptaasi-inhibiittori
FI970565L (fi)	1997-02-10	HIV-proteaasia inhiboiva yhdistelmä
LV10034A (lv)	1994-05-10	Miksto audu proteze
SE9501466D0 (sv)	1995-04-20	Antiviral protease inhibition