FI924043L - Menetelmä valmistaa farmaseuttisesti aktiivista 1- tai 3-difenyylimetyyli-imidatsoindolitsiinijohdannaista - Google Patents

Menetelmä valmistaa farmaseuttisesti aktiivista 1- tai 3-difenyylimetyyli-imidatsoindolitsiinijohdannaista Download PDF

Info

Publication number: FI924043L
Authority: FI; Finland
Prior art keywords: diphenylmethylimidazoindolizine; derivative; preparing; pharmaceutically active; pharmaceutically
Prior art date: 1991-09-10

Application number

FI924043A

Other languages

English (en)

Swedish (sv)

Other versions

FI98369B (fi

FI98369C (fi

FI924043A0 (fi

Inventor

Yasushi Honma

Yasuo Sekine

Sumihiro Nomura

Kazuaki Naito

Hiroshi Narita

Original Assignee

Tanabe Seiyaku Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-09-10

Filing date

1992-09-10

Publication date

1993-03-11

1992-09-10 Application filed by Tanabe Seiyaku Co filed Critical Tanabe Seiyaku Co

1992-09-10 Publication of FI924043A0 publication Critical patent/FI924043A0/fi

1993-03-11 Publication of FI924043L publication Critical patent/FI924043L/fi

1997-02-28 Publication of FI98369B publication Critical patent/FI98369B/fi

1997-06-10 Application granted granted Critical

1997-06-10 Publication of FI98369C publication Critical patent/FI98369C/fi

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/14—Ortho-condensed systems

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)

FI924043A 1991-09-10 1992-09-10 Menetelmä valmistaa farmaseuttisesti aktiivista 1- tai 3-difenyylimetyyli-imidatsoindolitsiinijohdannaista FI98369C (fi)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
JP30856091		1991-09-10
JP30856091		1991-09-10
JP5304492		1992-01-27
JP5304492		1992-01-27

Publications (4)

Publication Number	Publication Date
FI924043A0 FI924043A0 (fi)	1992-09-10
FI924043L true FI924043L (fi)	1993-03-11
FI98369B FI98369B (fi)	1997-02-28
FI98369C FI98369C (fi)	1997-06-10

Family

ID=26393753

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI924043A FI98369C (fi)	1991-09-10	1992-09-10	Menetelmä valmistaa farmaseuttisesti aktiivista 1- tai 3-difenyylimetyyli-imidatsoindolitsiinijohdannaista

Country Status (16)

Country	Link
US (1)	US5268377A (fi)
EP (1)	EP0531876B1 (fi)
JP (1)	JP2590797B2 (fi)
KR (1)	KR0168457B1 (fi)
AT (1)	ATE146474T1 (fi)
AU (1)	AU644539B2 (fi)
CA (1)	CA2077420C (fi)
DE (1)	DE69216013T2 (fi)
DK (1)	DK0531876T3 (fi)
ES (1)	ES2098403T3 (fi)
FI (1)	FI98369C (fi)
GR (1)	GR3022106T3 (fi)
ID (1)	ID902B (fi)
IL (1)	IL103021A (fi)
MY (1)	MY129927A (fi)
SG (1)	SG42962A1 (fi)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPH06271576A (ja) *	1993-03-19	1994-09-27	Upjohn Co:The	イミダゾール誘導体の製法
FR2712592B1 (fr) *	1993-11-17	1995-12-22	Adir	Nouveaux dérivés tricycliques azotés, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent.
US8969514B2 (en)	2007-06-04	2015-03-03	Synergy Pharmaceuticals, Inc.	Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
CA2688161C (en)	2007-06-04	2020-10-20	Kunwar Shailubhai	Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
ES2522968T3 (es)	2008-06-04	2014-11-19	Synergy Pharmaceuticals Inc.	Agonistas de guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros trastornos
WO2010009319A2 (en)	2008-07-16	2010-01-21	Synergy Pharmaceuticals Inc.	Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders
US9616097B2 (en)	2010-09-15	2017-04-11	Synergy Pharmaceuticals, Inc.	Formulations of guanylate cyclase C agonists and methods of use
CA2905438A1 (en)	2013-03-15	2014-09-25	Synergy Pharmaceuticals Inc.	Agonists of guanylate cyclase and their uses
EP2968439A2 (en)	2013-03-15	2016-01-20	Synergy Pharmaceuticals Inc.	Compositions useful for the treatment of gastrointestinal disorders
KR102272746B1 (ko)	2013-06-05	2021-07-08	보슈 헬스 아일랜드 리미티드	구아닐레이트 사이클라제 c의 초순수 작용제, 및 이의 제조 및 사용 방법
CN109715615A (zh)	2016-06-29	2019-05-03	蒙特利尔大学	联芳甲基杂环

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SU1047148A1 (ru) *	1981-03-30	1986-12-23	Институт физико-органической химии и углехимии АН УССР	Бензилиденпроизводные имидазо-[4,5-L]-индолизинов,обладающие бактериостатической и фунгистатической активностью
US4686226A (en) *	1985-09-03	1987-08-11	Merck & Co., Inc.	Substituted benzo[b]furo- and benzo[b]thieno quinolizines
US4816463A (en) *	1986-04-01	1989-03-28	Warner-Lambert Company	Substituted diimidazo [1,5-a: 4',5'-d]pyridines having antihypertensive activity
US4812462A (en) *	1986-04-01	1989-03-14	Warner-Lambert Company	4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine-6-carboxylic acid analogs having antihypertensive activity
CA1334092C (en) *	1986-07-11	1995-01-24	David John Carini	Angiotensin ii receptor blocking imidazoles
DE3928177A1 (de) *	1989-04-08	1991-02-28	Thomae Gmbh Dr K	Benzimidazole, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
IL96019A0 (en) *	1989-10-31	1991-07-18	Fujisawa Pharmaceutical Co	Imidazole derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same

1992
- 1992-09-02 DK DK92114987.8T patent/DK0531876T3/da active
- 1992-09-02 AU AU22056/92A patent/AU644539B2/en not_active Ceased
- 1992-09-02 ES ES92114987T patent/ES2098403T3/es not_active Expired - Lifetime
- 1992-09-02 IL IL10302192A patent/IL103021A/en not_active IP Right Cessation
- 1992-09-02 AT AT92114987T patent/ATE146474T1/de not_active IP Right Cessation
- 1992-09-02 DE DE69216013T patent/DE69216013T2/de not_active Expired - Fee Related
- 1992-09-02 EP EP92114987A patent/EP0531876B1/en not_active Expired - Lifetime
- 1992-09-02 CA CA002077420A patent/CA2077420C/en not_active Expired - Fee Related
- 1992-09-02 SG SG1996001486A patent/SG42962A1/en unknown
- 1992-09-03 US US07/939,652 patent/US5268377A/en not_active Expired - Fee Related
- 1992-09-07 MY MYPI92001597A patent/MY129927A/en unknown
- 1992-09-08 JP JP4239080A patent/JP2590797B2/ja not_active Expired - Lifetime
- 1992-09-08 KR KR1019920016409A patent/KR0168457B1/ko not_active Expired - Fee Related
- 1992-09-10 ID IDP469892A patent/ID902B/id unknown
- 1992-09-10 FI FI924043A patent/FI98369C/fi active
1996
- 1996-12-19 GR GR960403177T patent/GR3022106T3/el unknown

Also Published As

Publication number	Publication date
CA2077420C (en)	1998-08-25
IL103021A0 (en)	1993-02-21
KR930006024A (ko)	1993-04-20
ES2098403T3 (es)	1997-05-01
FI98369B (fi)	1997-02-28
GR3022106T3 (en)	1997-03-31
JP2590797B2 (ja)	1997-03-12
IL103021A (en)	1996-10-16
MY129927A (en)	2007-05-31
CA2077420A1 (en)	1993-03-11
KR0168457B1 (ko)	1999-01-15
DE69216013T2 (de)	1997-05-07
ID902B (id)	1996-09-09
EP0531876A3 (en)	1993-05-05
DK0531876T3 (fi)	1997-02-17
JPH05279365A (ja)	1993-10-26
AU2205692A (en)	1993-03-11
US5268377A (en)	1993-12-07
ATE146474T1 (de)	1997-01-15
SG42962A1 (en)	1997-10-17
EP0531876B1 (en)	1996-12-18
EP0531876A2 (en)	1993-03-17
FI98369C (fi)	1997-06-10
AU644539B2 (en)	1993-12-09
FI924043A0 (fi)	1992-09-10
DE69216013D1 (de)	1997-01-30

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Legal Events

Date	Code	Title	Description
1997-02-03	BB	Publication of examined application