FI921473L - Menetelmä terapeuttisesti käyttökelpoisten bentsimidatsolijohdannaisten valmistamiseksi - Google Patents

Menetelmä terapeuttisesti käyttökelpoisten bentsimidatsolijohdannaisten valmistamiseksi Download PDF

Info

Publication number: FI921473L
Authority: FI; Finland
Prior art keywords: preparation; therapeutically useful; benzimidazole derivatives; useful benzimidazole; derivatives
Prior art date: 1991-04-05

Application number

FI921473A

Other languages

English (en)

Swedish (sv)

Other versions

FI921473A0 (fi

FI99112B (fi

FI99112C (fi

Inventor

Maria Rosa Cuberes-Altisent

Constansa Jordi Frigola

Corominas Juan Pares

Original Assignee

Esteve Labor Dr

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-04-05

Filing date

1992-04-03

Publication date

1992-10-06

1992-04-03 Application filed by Esteve Labor Dr filed Critical Esteve Labor Dr

1992-04-03 Publication of FI921473A0 publication Critical patent/FI921473A0/fi

1992-10-06 Publication of FI921473L publication Critical patent/FI921473L/fi

1997-06-30 Publication of FI99112B publication Critical patent/FI99112B/fi

1997-10-10 Application granted granted Critical

1997-10-10 Publication of FI99112C publication Critical patent/FI99112C/fi

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Rheumatology (AREA)
Immunology (AREA)
Pain & Pain Management (AREA)
Pulmonology (AREA)
Anesthesiology (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

FI921473A 1991-04-05 1992-04-03 Menetelmä terapeuttisesti käyttökelpoisten bentsimidatsolijohdannaisten valmistamiseksi FI99112C (fi)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR9104171A FR2674856B1 (fr)	1991-04-05	1991-04-05	Nouveaux antihistaminiques non sedatifs, derives de benzimidazole, leur procede de preparation et leur utilisation en tant que medicaments.

Publications (4)

Publication Number	Publication Date
FI921473A0 FI921473A0 (fi)	1992-04-03
FI921473L true FI921473L (fi)	1992-10-06
FI99112B FI99112B (fi)	1997-06-30
FI99112C FI99112C (fi)	1997-10-10

Family

ID=9411523

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI921473A FI99112C (fi)	1991-04-05	1992-04-03	Menetelmä terapeuttisesti käyttökelpoisten bentsimidatsolijohdannaisten valmistamiseksi

Country Status (28)

Country	Link
US (1)	US5214040A (fi)
EP (1)	EP0507696B1 (fi)
JP (1)	JP3060054B2 (fi)
KR (1)	KR970011298B1 (fi)
CN (1)	CN1028367C (fi)
AT (1)	ATE126228T1 (fi)
AU (1)	AU647904B2 (fi)
BG (1)	BG60678B1 (fi)
BR (1)	BR1100983A (fi)
CA (1)	CA2065061A1 (fi)
CZ (1)	CZ279506B6 (fi)
DE (1)	DE69203911T2 (fi)
DK (1)	DK0507696T3 (fi)
ES (1)	ES2046110B1 (fi)
FI (1)	FI99112C (fi)
FR (1)	FR2674856B1 (fi)
GR (1)	GR3017643T3 (fi)
HU (1)	HU214316B (fi)
IL (1)	IL101483A (fi)
IS (1)	IS1639B (fi)
MX (1)	MX9201556A (fi)
NO (1)	NO179552C (fi)
NZ (1)	NZ242208A (fi)
PL (1)	PL167720B1 (fi)
RO (1)	RO109198B1 (fi)
RU (1)	RU2099336C1 (fi)
TW (1)	TW208003B (fi)
YU (1)	YU48826B (fi)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IT1264456B1 (it) *	1993-05-14	1996-09-23	Dompe Farmaceutici Spa	Derivati del 2-(benzimidazol-2-il)-1,3-diaminopropano farmacologicamente attivi.
FR2727865B1 (fr) *	1994-12-08	1997-07-18	Esteve Labor Dr	Utilisation des derives de 2-(4-(azolybutyl)-piperazinyl- (methyl))-benzimidazole et analogues ainsi que de leurs sels, pour la preparation de medicaments destines au traitement ou a la prophylaxie de l'asthme
EP0809641A1 (en) *	1995-02-15	1997-12-03	Neurogen Corporation	Certain bridged 4-phenyl-2-aminomethylimidazoles; new dopamine receptor subtype specific ligands
US5773616A (en) *	1995-02-15	1998-06-30	Neurogen Corporation	Certain bridged 4-phenyl-2-aminomethylimidazoles; new dopamine receptor subtype specific ligands
FR2731618B1 (fr) *	1995-03-14	1997-08-01	Esteve Labor Dr	Composition ophtalmique topique comprenant un derive de 2-(4-(azolylbutyl)-piperazinyl-methyl)-benzimidazole, notamment pour le traitement de la conjonctivite allergique
US6211199B1 (en)	1995-11-17	2001-04-03	Aventis Pharmaceuticals Inc.	Substituted 4-(1H-benzimidazol-2-yl-amino)piperidines useful for the treatment of allergic diseases
US6194406B1 (en)	1995-12-20	2001-02-27	Aventis Pharmaceuticals Inc.	Substituted 4-(1H-benzimidazol-2-yl)[1,4]diazepanes useful for the treatment of allergic disease
US6423704B2 (en)	1995-12-20	2002-07-23	Aventis Pharmaceuticals Inc.	Substituted 4-(1H-benzimidazol-2-yl)[1,4]diazepanes useful for the treatment of allergic diseases
US5998439A (en) *	1996-02-21	1999-12-07	Hoescht Marion Roussel, Inc.	Substituted N-methyl-N-(4-(piperidin-1-yl)-2-(aryl)butyl)benzamides useful for the treatment of allergic diseases
US5922737A (en) *	1996-02-21	1999-07-13	Hoechst Marion Roussel, Inc.	Substituted N-methyl-N-(4-(4-(1H-Benzimidazol-2-YL-amino) piperidin-1-YL)-2-(arlyl) butyl) benzamides useful for the treatment of allergic diseases
US5932571A (en) *	1996-02-21	1999-08-03	Hoechst Marion Roussel, Inc.	Substituted N-methyl-N-(4-(4-(1H-benzimidazol-2-yl) {1,4}diazepan-1-yl)-2-(aryl) butyl) benzamides useful for the treatment of allergic diseases
TWI225488B (en) *	1999-12-21	2004-12-21	Janssen Pharmaceutica Nv	Derivatives of homopiperidinyl substituted benzimidazole analogues
WO2001053257A2 (en) *	2000-01-19	2001-07-26	Cadila Healthcare Ltd.	Compounds having hypolipedemic and hypocholesteremic activities, process for their preparation and pharmaceutical compositions containing them
HUP0301550A2 (hu) *	2000-10-31	2003-09-29	Basf Aktiengesellschaft	Hiper-elágazó poliuretánok alkalmazása nyomdafestékek elżállítására
US7160879B2 (en) *	2002-01-10	2007-01-09	Neurogen Corporation	Melanin concentrating hormone receptor ligands: substituted 2-(4-benzyl-piperazin-1-ylmethyl)- and 2-(4-benzyl-diazepan-1-ylmethyl)-1H-benzoimidazole analogues
CN101089000B (zh) *	2006-06-16	2011-01-05	北京大学	螺环哌嗪季铵盐类化合物及其制备方法和应用
AU2010257802A1 (en) *	2009-06-11	2012-01-12	Siena Biotech S.P.A.	Hedgehog pathway antagonists and therapeutic applications thereof
PL2938597T3 (pl) *	2012-12-27	2017-03-31	Alzprotect	Sole siarczanowe n-(3-(4-(3-(diizobutyloamino)propylo)piperazyn-1-ylo)propylo)-1h-benzo[d]imidazolo-2-aminy, ich wytwarzanie oraz ich zastosowanie
KR102057075B1 (ko) *	2018-11-30	2019-12-19	우승열	페트병에 장착되는 여과장치

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4200641A (en) *	1976-12-21	1980-04-29	Janssen Pharmaceutica, N.V.	1-[(Heterocyclyl)-alkyl]-4-diarylmethoxy piperidine derivatives
DE3336409A1 (de) *	1983-10-06	1985-04-18	Ludwig Heumann & Co GmbH, 8500 Nürnberg	Chinazolinderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
US5010075A (en) *	1987-04-24	1991-04-23	Syntex Pharmaceuticals Ltd.	Substituted imidazolyl-alkyl-piperazine and -diazepine derivatives
CA1317939C (en) *	1987-07-01	1993-05-18	Janssen Pharmaceutica Naamloze Vennootschap	¬(bicyclic heterocyclyl)methyl and -hetero\| substituted hexahydro-1h-azepines and pyrrolidines
FR2665161B1 (fr) *	1990-07-26	1992-11-27	Esteve Labor Dr	Nouveaux derives de benzimidazole, leur preparation et leur application en tant que medicaments.

1991
- 1991-04-05 FR FR9104171A patent/FR2674856B1/fr not_active Expired - Fee Related
1992
- 1992-03-31 TW TW081102419A patent/TW208003B/zh active
- 1992-03-31 YU YU33692A patent/YU48826B/sh unknown
- 1992-04-01 RU SU925011426A patent/RU2099336C1/ru active
- 1992-04-02 NZ NZ242208A patent/NZ242208A/en unknown
- 1992-04-02 AU AU13979/92A patent/AU647904B2/en not_active Ceased
- 1992-04-02 IS IS3832A patent/IS1639B/is unknown
- 1992-04-02 RO RO92-200447A patent/RO109198B1/ro unknown
- 1992-04-03 PL PL92294101A patent/PL167720B1/pl unknown
- 1992-04-03 KR KR1019920005583A patent/KR970011298B1/ko not_active Expired - Fee Related
- 1992-04-03 FI FI921473A patent/FI99112C/fi active
- 1992-04-03 DK DK92400940.0T patent/DK0507696T3/da active
- 1992-04-03 MX MX9201556A patent/MX9201556A/es unknown
- 1992-04-03 CA CA002065061A patent/CA2065061A1/fr not_active Abandoned
- 1992-04-03 BG BG96180A patent/BG60678B1/bg unknown
- 1992-04-03 ES ES09200813A patent/ES2046110B1/es not_active Expired - Lifetime
- 1992-04-03 AT AT92400940T patent/ATE126228T1/de not_active IP Right Cessation
- 1992-04-03 DE DE69203911T patent/DE69203911T2/de not_active Expired - Fee Related
- 1992-04-03 CZ CS921017A patent/CZ279506B6/cs not_active IP Right Cessation
- 1992-04-03 HU HU9201145A patent/HU214316B/hu not_active IP Right Cessation
- 1992-04-03 NO NO921315A patent/NO179552C/no not_active IP Right Cessation
- 1992-04-03 IL IL10148392A patent/IL101483A/en not_active IP Right Cessation
- 1992-04-03 EP EP92400940A patent/EP0507696B1/fr not_active Expired - Lifetime
- 1992-04-03 US US07/863,208 patent/US5214040A/en not_active Expired - Fee Related
- 1992-04-04 CN CN92102353A patent/CN1028367C/zh not_active Expired - Fee Related
- 1992-04-06 JP JP4084230A patent/JP3060054B2/ja not_active Expired - Lifetime
1995
- 1995-10-04 GR GR950402756T patent/GR3017643T3/el unknown
1997
- 1997-05-14 BR BR1100983-7A patent/BR1100983A/pt active IP Right Grant

Also Published As

Publication number	Publication date
ATE126228T1 (de)	1995-08-15
CS101792A3 (en)	1992-10-14
HU9201145D0 (en)	1992-06-29
US5214040A (en)	1993-05-25
FR2674856A1 (fr)	1992-10-09
NO179552B (no)	1996-07-22
BG60678B1 (bg)	1995-12-29
EP0507696A1 (fr)	1992-10-07
TW208003B (fi)	1993-06-21
BR1100983A (pt)	1999-10-13
CN1065460A (zh)	1992-10-21
PL294101A1 (en)	1992-11-30
ES2046110A1 (es)	1994-01-16
FR2674856B1 (fr)	1993-07-30
ES2046110B1 (es)	1994-08-01
JP3060054B2 (ja)	2000-07-04
GR3017643T3 (en)	1996-01-31
DE69203911D1 (de)	1995-09-14
HUT60732A (en)	1992-10-28
IL101483A (en)	1995-12-08
DE69203911T2 (de)	1995-12-07
HU214316B (hu)	1998-03-02
FI921473A0 (fi)	1992-04-03
CA2065061A1 (fr)	1992-10-06
RO109198B1 (ro)	1994-12-30
RU2099336C1 (ru)	1997-12-20
AU647904B2 (en)	1994-03-31
KR970011298B1 (ko)	1997-07-09
JPH0597846A (ja)	1993-04-20
NZ242208A (en)	1993-10-26
YU33692A (sh)	1995-03-27
NO921315L (no)	1992-10-06
PL167720B1 (pl)	1995-10-31
FI99112B (fi)	1997-06-30
KR920019781A (ko)	1992-11-20
FI99112C (fi)	1997-10-10
CZ279506B6 (cs)	1995-05-17
DK0507696T3 (da)	1995-09-18
MX9201556A (es)	1992-10-01
AU1397992A (en)	1992-10-08
IL101483A0 (en)	1992-12-30
NO921315D0 (no)	1992-04-03
IS3832A (is)	1992-10-06
IS1639B (is)	1997-03-25
NO179552C (no)	1996-10-30
EP0507696B1 (fr)	1995-08-09
BG96180A (bg)	1993-12-24
CN1028367C (zh)	1995-05-10
YU48826B (sh)	2002-03-18

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FI873205A0 (fi)	1987-07-21	Menetelmä terapeuttisesti aktiivisten bentsimidatsolijohdannaisten valmistamiseksi
FI103967B1 (fi)	1999-10-29	Menetelmä tetrahydrokarbatsonijohdannaisten valmistamiseksi
FI883050L (fi)	1988-12-25	Menetelmä terapeuttisesti aktiivisten pyranoindolitsinokinoliinijohdannaisten valmistamiseksi
FI921473L (fi)	1992-10-06	Menetelmä terapeuttisesti käyttökelpoisten bentsimidatsolijohdannaisten valmistamiseksi
NO180749C (no)	1997-06-11	Analogifremgangsmåte for fremstilling av terapeutisk aktive benzimidazolsubstituerte derivater
FI892182A (fi)	1989-11-07	Menetelmä terapeuttisesti käyttökelpoisten kromaanijohdannaisten valmistamiseksi
FI923527L (fi)	1992-08-05	Menetelmä terapeuttisesti käyttökelpoisten 3-piperidino-4-hydroksikromaanijohdannaisten valmistamiseksi
FI906408L (fi)	1991-06-29	Menetelmä terapeuttisesti käyttökelpoisten 2-aminopyrimidiini-4-karboksamidijohdannaisten valmistamiseksi
FI93215C (fi)	1995-03-10	Menetelmä terapeuttisesti käyttökelpoisten aminoalkoksifenyylijohdannaisten valmistamiseksi
FI104075B1 (fi)	1999-11-15	Menetelmä terapeuttisesti käyttökelpoisten 2-karboksitienyylikarbamoyylipyrrolidin-4-yylitiokarbapeneemi-3-karboksyylihappojohdannaisten valmistamiseksi
FI884910A (fi)	1989-04-28	Menetelmä terapeuttisesti käyttökelpoisten bentsopyraanijohdannaisten valmistamiseksi
FI924642L (fi)	1992-10-14	Menetelmä terapeuttisesti aktiivisten 3-indolyylitioasetaattijohdannaisten valmistamiseksi
FI893003L (fi)	1989-12-21	Menetelmä uusien terapeuttisesti käyttökelpoisten neplanosiinijohdannaisten valmistamiseksi
FI98461B (fi)	1997-03-14	Menetelmä terapeuttisesti käyttökelpoisten yhdisteiden valmistamiseksi
FI903077A0 (fi)	1990-06-19	Menetelmä valmistaa terapeuttisesti aktiivisia R(-)-3-kinuklidinolijohdannaisia
FI924043L (fi)	1993-03-11	Menetelmä valmistaa farmaseuttisesti aktiivista 1- tai 3-difenyylimetyyli-imidatsoindolitsiinijohdannaista
FI94351B (fi)	1995-05-15	Menetelmä terapeuttisesti käyttökelpoisten peptidijohdannaisten valmistamiseksi
FI883930L (fi)	1989-02-26	Analogiamenetelmä terapeuttisesti käyttökelpoisten bentsimidatsolijohdannaisten valmistamiseksi
FI92188C (fi)	1994-10-10	Menetelmä terapeuttisesti käyttökelpoisten fenoksialkyylipyrokatekolijohdannaisten valmistamiseksi
NO179517C (no)	1996-10-23	Fremgangsmåte for fremstilling av 8-klorkinolonderivater
FI922835L (fi)	1992-06-17	Menetelmä terapeuttisesti aktiivisten piperidiinijohdannaisten valmistamiseksi

Legal Events

Date	Code	Title	Description
1997-06-02	BB	Publication of examined application