FI921456L - Substituerade 2',3'-didesoxi-5-trifluormetyluridiner, foerfaranden foer deras framstaellning och deras anvaendning i laekemedel - Google Patents

Substituerade 2',3'-didesoxi-5-trifluormetyluridiner, foerfaranden foer deras framstaellning och deras anvaendning i laekemedel Download PDF

Info

Publication number: FI921456L
Authority: FI; Finland
Prior art keywords: deras; trifluormethyluridiner; didesoxi; laekemedel; substituerade
Prior art date: 1991-04-05

Application number

FI921456A

Other languages

English (en)

Other versions

FI921456A7 (fi

FI921456A0 (fi

Inventor

Dieter Haebich

Rainer Neumann

Original Assignee

Bayer Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-04-05

Filing date

1992-04-02

Publication date

1992-10-06

1992-04-02 Application filed by Bayer Ag filed Critical Bayer Ag

1992-04-02 Publication of FI921456A0 publication Critical patent/FI921456A0/fi

1992-10-06 Publication of FI921456L publication Critical patent/FI921456L/fi

1992-10-06 Publication of FI921456A7 publication Critical patent/FI921456A7/fi

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
- A61K31/7072—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid having two oxo groups directly attached to the pyrimidine ring, e.g. uridine, uridylic acid, thymidine, zidovudine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
- C07H19/10—Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Biotechnology (AREA)
Biochemistry (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Epidemiology (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Gastroenterology & Hepatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Plural Heterocyclic Compounds (AREA)

FI921456A 1991-04-05 1992-04-02 Substituoituja 2',3'-didesoksi-5-trifluorimetyyliuridiineja, menetelmiä niiden valmistamiseksi ja niiden käyttö lääkeaineissa FI921456A7 (fi)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE4110977A DE4110977A1 (de)	1991-04-05	1991-04-05	Substituierte 2',3'-didesoxy-5-trifluormethyluridine, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln

Publications (3)

Publication Number	Publication Date
FI921456A0 FI921456A0 (fi)	1992-04-02
FI921456L true FI921456L (fi)	1992-10-06
FI921456A7 FI921456A7 (fi)	1992-10-06

Family

ID=6428857

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI921456A FI921456A7 (fi)	1991-04-05	1992-04-02	Substituoituja 2',3'-didesoksi-5-trifluorimetyyliuridiineja, menetelmiä niiden valmistamiseksi ja niiden käyttö lääkeaineissa

Country Status (15)

Country	Link
EP (1)	EP0507188A1 (fi)
JP (1)	JPH05148261A (fi)
KR (1)	KR920019813A (fi)
CN (1)	CN1065462A (fi)
AU (1)	AU640860B2 (fi)
CA (1)	CA2064916A1 (fi)
CS (1)	CS92092A3 (fi)
DE (1)	DE4110977A1 (fi)
FI (1)	FI921456A7 (fi)
HU (1)	HUT60748A (fi)
IE (1)	IE921083A1 (fi)
IL (1)	IL101482A0 (fi)
NO (1)	NO921086L (fi)
NZ (1)	NZ242205A (fi)
TW (1)	TW205043B (fi)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN1050846C (zh) *	1995-08-03	2000-03-29	中国医学科学院医药生物技术研究所	一种抗肿瘤抗生素云南霉素及其制备方法
AU2002257446A1 (en) *	2001-05-18	2002-12-03	Rakesh Kumar	Antiviral nucleosides
CN100334100C (zh) *	2004-01-17	2007-08-29	杭州富邦生物制药有限公司	5－三氟甲基－2’－脱氧尿苷的合成方法
JP4603274B2 (ja) *	2004-02-24	2010-12-22	三井化学株式会社	２’−デオキシ−５−トリフルオロメチルウリジンの製造方法
WO2009119785A1 (ja) *	2008-03-28	2009-10-01	浜理薬品工業株式会社	エチニルチミジン化合物の精製方法
WO2009125841A1 (ja) *	2008-04-10	2009-10-15	浜理薬品工業株式会社	５－メチルウリジンを出発原料とするエチニルチミジン化合物の製造方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3048877A1 (de) *	1980-12-23	1982-07-08	Kailash Kumar Prof. Dr. 2359 Lentföhrden Gauri	Pyrimidinnucleosid-phosphonate, verfahren zur herstellung und sie enthaltende mittel
FI87783C (fi) *	1985-05-15	1993-02-25	Wellcome Found	Foerfarande foer framstaellning av terapeutiskt anvaendbara 2',3'-dideoxinukleosider
DE3650741T2 (de) *	1985-09-17	2000-10-12	The Wellcome Foundation Ltd., Greenford	Kombination therapeutische Nukleoside mit weiteren therapeutisch wirksamen Komponenten.
CA1327000C (en) *	1987-08-07	1994-02-15	David L.J. Tyrrell	Antiviral therapy for hepatitis b
SE8704298D0 (sv) *	1987-11-03	1987-11-03	Astra Ab	Compounds for use in therapy
US4900828A (en) *	1988-05-12	1990-02-13	Hoffmann-Laroche Inc.	Intermediate compounds and an improved procedure for the synthesis of 2',3'-dideoxycytidine
SE8802173D0 (sv) *	1988-06-10	1988-06-10	Astra Ab	Pyrimidine derivatives
GB8823320D0 (en) *	1988-10-05	1988-11-09	Nycomed As	Chemical compounds
WO1990014079A1 (en) *	1989-05-15	1990-11-29	The United States Of America, Represented By The Secretary, United States Department Of Commerce	Method of treatment of hepatitis
NZ234534A (en) *	1989-07-17	1994-12-22	Univ Birmingham	Pyrimidine 4'-thionucleoside derivatives and their preparation; intermediates therefor

1991
- 1991-04-05 DE DE4110977A patent/DE4110977A1/de not_active Withdrawn
1992
- 1992-03-06 TW TW081101706A patent/TW205043B/zh active
- 1992-03-10 AU AU12190/92A patent/AU640860B2/en not_active Ceased
- 1992-03-19 NO NO92921086A patent/NO921086L/no unknown
- 1992-03-24 EP EP92105039A patent/EP0507188A1/de not_active Withdrawn
- 1992-03-26 CS CS92920A patent/CS92092A3/cs unknown
- 1992-04-02 FI FI921456A patent/FI921456A7/fi not_active Application Discontinuation
- 1992-04-02 CA CA002064916A patent/CA2064916A1/en not_active Abandoned
- 1992-04-02 NZ NZ242205A patent/NZ242205A/en unknown
- 1992-04-02 HU HU9201117A patent/HUT60748A/hu unknown
- 1992-04-03 IE IE108392A patent/IE921083A1/en unknown
- 1992-04-03 JP JP4112074A patent/JPH05148261A/ja active Pending
- 1992-04-03 IL IL101482A patent/IL101482A0/xx unknown
- 1992-04-04 CN CN92102448A patent/CN1065462A/zh active Pending
- 1992-04-04 KR KR1019920005650A patent/KR920019813A/ko not_active Withdrawn

Also Published As

Publication number	Publication date
AU1219092A (en)	1992-10-08
NO921086D0 (no)	1992-03-19
HUT60748A (en)	1992-10-28
NO921086L (no)	1992-10-06
DE4110977A1 (de)	1992-10-08
CA2064916A1 (en)	1992-10-06
IL101482A0 (en)	1992-12-30
JPH05148261A (ja)	1993-06-15
NZ242205A (en)	1993-04-28
CN1065462A (zh)	1992-10-21
CS92092A3 (en)	1992-12-16
FI921456A7 (fi)	1992-10-06
TW205043B (fi)	1993-05-01
FI921456A0 (fi)	1992-04-02
AU640860B2 (en)	1993-09-02
IE921083A1 (en)	1992-10-07
KR920019813A (ko)	1992-11-20
HU9201117D0 (en)	1992-06-29
EP0507188A1 (de)	1992-10-07

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Legal Events

Date	Code	Title	Description
1994-05-06	FD	Application lapsed