FI924084L - Tramadol-n-oxidmaterial, enantiomerer och kompositioner daerav och deras anvaendning - Google Patents

Tramadol-n-oxidmaterial, enantiomerer och kompositioner daerav och deras anvaendning Download PDF

Info

Publication number: FI924084L
Authority: FI; Finland
Prior art keywords: och; oxidmaterial; enantiomerer; tramadol; kompositioner
Prior art date: 1991-09-13

Application number

FI924084A

Other languages

English (en)

Other versions

FI924084A0 (fi

FI111717B (fi

Inventor

Cynthia A Maryanoff

Robert B Raffa

Frank J Villani

Original Assignee

Mcneilab Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-09-13

Filing date

1992-09-11

Publication date

1993-03-14

1992-09-11 Application filed by Mcneilab Inc filed Critical Mcneilab Inc

1992-09-11 Publication of FI924084A0 publication Critical patent/FI924084A0/fi

1993-03-14 Publication of FI924084L publication Critical patent/FI924084L/fi

2003-09-15 Application granted granted Critical

2003-09-15 Publication of FI111717B publication Critical patent/FI111717B/fi

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C291/00—Compounds containing carbon and nitrogen and having functional groups not covered by groups C07C201/00 - C07C281/00
- C07C291/02—Compounds containing carbon and nitrogen and having functional groups not covered by groups C07C201/00 - C07C281/00 containing nitrogen-oxide bonds
- C07C291/04—Compounds containing carbon and nitrogen and having functional groups not covered by groups C07C201/00 - C07C281/00 containing nitrogen-oxide bonds containing amino-oxide bonds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/14—Antitussive agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Pulmonology (AREA)
Pain & Pain Management (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Cosmetics (AREA)
Catching Or Destruction (AREA)

FI924084A 1991-09-13 1992-09-11 Menetelmä terapeuttisesti käyttökelpoisen 2-[(dimetyyliamino)metyyli]-1-(3-metoksifenyyli)sykloheksanoli-N-oksidin valmistamiseksi FI111717B (fi)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US07/759,259 US5223541A (en)	1991-09-13	1991-09-13	Tramadol n-oxide material, enantiomers and compositions thereof, and their use
US75925991		1991-09-13

Publications (3)

Publication Number	Publication Date
FI924084A0 FI924084A0 (fi)	1992-09-11
FI924084L true FI924084L (fi)	1993-03-14
FI111717B FI111717B (fi)	2003-09-15

Family

ID=25054992

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI924084A FI111717B (fi)	1991-09-13	1992-09-11	Menetelmä terapeuttisesti käyttökelpoisen 2-[(dimetyyliamino)metyyli]-1-(3-metoksifenyyli)sykloheksanoli-N-oksidin valmistamiseksi

Country Status (23)

Country	Link
US (1)	US5223541A (fi)
EP (1)	EP0532348B1 (fi)
JP (1)	JP3115119B2 (fi)
KR (1)	KR100241859B1 (fi)
CN (1)	CN1032533C (fi)
AT (1)	ATE132852T1 (fi)
AU (1)	AU651000B2 (fi)
CA (1)	CA2078028C (fi)
DE (1)	DE69207526T2 (fi)
DK (1)	DK0532348T3 (fi)
ES (1)	ES2086079T3 (fi)
FI (1)	FI111717B (fi)
GR (1)	GR3019345T3 (fi)
HU (1)	HU214321B (fi)
IL (1)	IL103154A (fi)
MX (1)	MX9205219A (fi)
MY (1)	MY121910A (fi)
NO (1)	NO178105C (fi)
NZ (1)	NZ244309A (fi)
SG (1)	SG63550A1 (fi)
TW (1)	TW221968B (fi)
ZA (1)	ZA926968B (fi)
ZW (1)	ZW14592A1 (fi)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DK0566709T5 (da)	1991-09-06	2009-05-18	Ortho Mcneil Janssen Pharm	Præparat indeholdende et tramadolmateriale og acetaminophen og anvendelse deraf
US5968551A (en)	1991-12-24	1999-10-19	Purdue Pharma L.P.	Orally administrable opioid formulations having extended duration of effect
US5958459A (en) *	1991-12-24	1999-09-28	Purdue Pharma L.P.	Opioid formulations having extended controlled released
US5478577A (en) *	1993-11-23	1995-12-26	Euroceltique, S.A.	Method of treating pain by administering 24 hour oral opioid formulations exhibiting rapid rate of initial rise of plasma drug level
US7740881B1 (en)	1993-07-01	2010-06-22	Purdue Pharma Lp	Method of treating humans with opioid formulations having extended controlled release
IL110014A (en)	1993-07-01	1999-11-30	Euro Celtique Sa	Solid controlled-release oral dosage forms of opioid analgesics
US5879705A (en) *	1993-07-27	1999-03-09	Euro-Celtique S.A.	Sustained release compositions of morphine and a method of preparing pharmaceutical compositions
US6017963A (en) *	1995-11-14	2000-01-25	Euro-Celtique, S.A.	Formulation for intranasal administration
ATE226931T1 (de)	1997-07-15	2002-11-15	Russinsky Ltd	Verfahren zur herstellung von reinem cis-tramadol
US6156342A (en) *	1998-05-26	2000-12-05	Andex Pharmaceuticals, Inc.	Controlled release oral dosage form
US6806294B2 (en)	1998-10-15	2004-10-19	Euro-Celtique S.A.	Opioid analgesic
ES2374717T3 (es)	1999-10-29	2012-02-21	Euro-Celtique S.A.	Formulaciones de hidrocodona de liberación controlada.
US10179130B2 (en)	1999-10-29	2019-01-15	Purdue Pharma L.P.	Controlled release hydrocodone formulations
DE10000312A1 (de) *	2000-01-05	2001-07-12	Gruenenthal Gmbh	Substituierte Aminomethyl-Phenyl-Cyclohexanderivate
KR100968128B1 (ko)	2000-10-30	2010-07-06	유로-셀티크 소시에떼 아노뉨	서방성 하이드로코돈 제형
CA2758923A1 (en)	2001-03-16	2002-09-26	Dmi Biosciences, Inc.	Use of tramadol to delay ejaculation
US20110104214A1 (en)	2004-04-15	2011-05-05	Purdue Pharma L.P.	Once-a-day oxycodone formulations
UA81224C2 (uk)	2001-05-02	2007-12-25	Euro Celtic S A	Дозована форма оксикодону та її застосування
US6649783B2 (en) *	2001-10-03	2003-11-18	Euro-Celtique, S.A.	Synthesis of (+/-)-2-((dimethylamino)methyl)-1-(aryl)cyclohexanols
WO2003048113A1 (en)	2001-11-30	2003-06-12	Sepracor Inc.	Tramadol analogs and uses thereof
US9092841B2 (en)	2004-06-09	2015-07-28	Cognex Technology And Investment Llc	Method and apparatus for visual detection and inspection of objects
US7940687B2 (en)	2005-11-16	2011-05-10	Qualcomm Incorporated	Efficient partitioning of control and data fields
KR20090121315A (ko) *	2007-02-12	2009-11-25	디엠아이 바이오사이언시스 인코포레이티드	조루 및 발기부전을 동시에 치료하는 방법
DK2114147T3 (da) *	2007-02-12	2012-06-25	Dmi Biosciences Inc	Reduktion af bivirkninger af tramadol
KR20100040881A (ko) *	2007-06-26	2010-04-21	솔베이 파마슈티칼스 비. 브이	전구약물로서 벤라팍신 및 ｏ－데스메틸벤라팍신의 ｎ－옥사이드
US20100003322A1 (en) *	2008-07-03	2010-01-07	Lai Felix S	Enteric coated hydrophobic matrix formulation
US10475492B1 (en)	2018-07-27	2019-11-12	Macronix International Co., Ltd.	Circuit and method for read latency control

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3652589A (en) *	1967-07-27	1972-03-28	Gruenenthal Chemie	1-(m-substituted phenyl)-2-aminomethyl cyclohexanols
US4017637A (en) *	1973-03-26	1977-04-12	American Home Products Corporation	Benzylamine analgesics
DE3515349A1 (de) *	1985-04-27	1986-10-30	Messerschmitt-Bölkow-Blohm GmbH, 8012 Ottobrunn	Elektrischer geber zur messung mechanischer groessen

1991
- 1991-09-13 US US07/759,259 patent/US5223541A/en not_active Expired - Lifetime
1992
- 1992-09-11 MX MX9205219A patent/MX9205219A/es unknown
- 1992-09-11 CA CA002078028A patent/CA2078028C/en not_active Expired - Lifetime
- 1992-09-11 CN CN92111582A patent/CN1032533C/zh not_active Expired - Lifetime
- 1992-09-11 DE DE69207526T patent/DE69207526T2/de not_active Expired - Lifetime
- 1992-09-11 FI FI924084A patent/FI111717B/fi not_active IP Right Cessation
- 1992-09-11 NZ NZ244309A patent/NZ244309A/en not_active IP Right Cessation
- 1992-09-11 ES ES92308298T patent/ES2086079T3/es not_active Expired - Lifetime
- 1992-09-11 HU HU9202918A patent/HU214321B/hu unknown
- 1992-09-11 AT AT92308298T patent/ATE132852T1/de active
- 1992-09-11 NO NO923530A patent/NO178105C/no not_active IP Right Cessation
- 1992-09-11 DK DK92308298.6T patent/DK0532348T3/da active
- 1992-09-11 AU AU23557/92A patent/AU651000B2/en not_active Expired
- 1992-09-11 EP EP92308298A patent/EP0532348B1/en not_active Expired - Lifetime
- 1992-09-11 SG SG1996001523A patent/SG63550A1/en unknown
- 1992-09-11 ZA ZA926968A patent/ZA926968B/xx unknown
- 1992-09-12 MY MYPI92001635A patent/MY121910A/en unknown
- 1992-09-13 IL IL10315492A patent/IL103154A/en not_active IP Right Cessation
- 1992-09-14 JP JP04269183A patent/JP3115119B2/ja not_active Expired - Lifetime
- 1992-09-14 ZW ZW14592A patent/ZW14592A1/xx unknown
- 1992-09-14 KR KR1019920016819A patent/KR100241859B1/ko not_active Expired - Lifetime
- 1992-11-10 TW TW081108968A patent/TW221968B/zh not_active IP Right Cessation
1996
- 1996-03-19 GR GR960400740T patent/GR3019345T3/el unknown

Also Published As

Publication number	Publication date
EP0532348A3 (en)	1993-05-26
NO923530L (no)	1993-03-15
HUT65476A (en)	1994-06-28
HU9202918D0 (en)	1992-11-30
AU651000B2 (en)	1994-07-07
FI924084A0 (fi)	1992-09-11
DK0532348T3 (da)	1996-02-05
HU214321B (hu)	1998-03-02
ZW14592A1 (en)	1994-05-11
KR100241859B1 (ko)	2000-02-01
KR930005969A (ko)	1993-04-20
JP3115119B2 (ja)	2000-12-04
GR3019345T3 (en)	1996-06-30
MX9205219A (es)	1994-02-28
EP0532348B1 (en)	1996-01-10
NO178105C (no)	1996-01-24
EP0532348A2 (en)	1993-03-17
AU2355792A (en)	1993-03-18
CA2078028A1 (en)	1993-03-14
SG63550A1 (en)	1999-03-30
MY121910A (en)	2006-03-31
JPH06122668A (ja)	1994-05-06
CA2078028C (en)	2003-04-29
ES2086079T3 (es)	1996-06-16
FI111717B (fi)	2003-09-15
CN1071913A (zh)	1993-05-12
NO923530D0 (no)	1992-09-11
NZ244309A (en)	1994-10-26
IL103154A (en)	1996-09-12
IL103154A0 (en)	1993-02-21
ATE132852T1 (de)	1996-01-15
US5223541A (en)	1993-06-29
DE69207526D1 (de)	1996-02-22
TW221968B (fi)	1994-04-01
NO178105B (no)	1995-10-16
ZA926968B (en)	1994-03-11
CN1032533C (zh)	1996-08-14
DE69207526T2 (de)	1996-07-04

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Legal Events

Date	Code	Title	Description
2012-11-01	MA	Patent expired